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Journal Articles

A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens

Blood (2018) 132 (18): 1911–1921.

https://doi.org/10.1182/blood-2018-04-843763

Published: 2018

Includes: Supplemental data

Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Harbors Frequent Splicesosome Mutations That Cause Aberrant RNA Splicing Affecting Genes Critical in pDC Differentiation and Function

Blood (2016) 128 (22): 738.

https://doi.org/10.1182/blood.V128.22.738.738

Published: 2016

Journal Articles

Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program

Sun Mi Park, PhD, Mithat Gönen, PhD, Ly P. Vu, PhD, Gerard Minuesa, PhD, Patrick Tivnan, Trevor Barlowe, James Taggart, Yuheng Lu, Raquel P Deering, PhD, Nir Hacohen, PhD, Maria Figueroa, MD, Elisabeth M. Paietta, PhD, Martin S. Tallman, MD, Ari M. Melnick, MD, Ross L. Levine, MD, Christina Leslie, PhD, Christopher J Lengner, PhD, Michael G Kharas, PhD

Blood (2014) 124 (21): 836.

https://doi.org/10.1182/blood.V124.21.836.836

Published: 2014

Journal Articles

Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

Blood (2014) 124 (7): 1089–1098.

https://doi.org/10.1182/blood-2014-01-552067

Published: 2014

Includes: Supplemental data

Journal Articles

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Mohini Rajasagi, Sachet A. Shukla, Edward F. Fritsch, Derin B. Keskin, David DeLuca, Ellese Carmona, Wandi Zhang, Carrie Sougnez, Kristian Cibulskis, John Sidney, Kristen Stevenson, Jerome Ritz, Donna Neuberg, Vladimir Brusic, Stacey Gabriel, Eric S. Lander, Gad Getz, Nir Hacohen, Catherine J. Wu

Blood (2014) 124 (3): 453–462.

https://doi.org/10.1182/blood-2014-04-567933

Published: 2014

Includes: Supplemental data

Journal Articles

Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion

Pavan Bachireddy, Ursula Hainz, Michael Rooney, Olga Pozdnyakova, Julie Aldridge, Wandi Zhang, Xiaoyun Liao, F. Stephen Hodi, Karyn O’Connell, W. Nicholas Haining, Natalie R. Goldstein, Christine M. Canning, Robert J. Soiffer, Jerome Ritz, Nir Hacohen, Edwin P. Alyea, III, Haesook T. Kim, Catherine J. Wu

Blood (2014) 123 (9): 1412–1421.

https://doi.org/10.1182/blood-2013-08-523001

Published: 2014

Includes: Supplemental data

Journal Articles

Tumor Neoantigens Are Abundant Across Cancers

Mohini Rajasagi, PhD, Sachet A. Shukla, Edward F. Fritsch, David DeLuca, PhD, Gad Getz, Ph.D., Nir Hacohen, PhD, Catherine J. Wu, MD

Blood (2013) 122 (21): 3265.

https://doi.org/10.1182/blood.V122.21.3265.3265

Published: 2013

Journal Articles

Reconstructing a Genotype-Phenotype Map In Chronic Lymphocytic Leukemia

Dylan Kotliar, BA, Dan-Avi Landau, MD, PhD, Oren Litvin, BA, Petar Stojanov, Carrie Sougnez, Gordon Saksena, M. Eng, Donna S. Neuberg, ScD, Gad Getz, Jennifer R Brown, MD, PhD, Dana Pe'er, Ph.D., Nir Hacohen, PhD, Catherine J. Wu, MD

Blood (2013) 122 (21): 2857.

https://doi.org/10.1182/blood.V122.21.2857.2857

Published: 2013

Journal Articles

Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution

Blood (2013) 122 (21): 596.

https://doi.org/10.1182/blood.V122.21.596.596

Published: 2013

Journal Articles

Reversal of T Cell Exhaustion in Pre-Treatment Marrow T Cells Is Associated with Effective Graft-Versus-Leukemia Responses to Donor Lymphocyte Infusion

Pavan Bachireddy, MD, Ursula Hainz, PhD, Michael Rooney, BSc, Olga Pozdnyakova, MD, PhD, Julie Aldridge, MS, W. Nicholas Haining, B.M., B.Ch., Natalie R. Goldstein, Christine M Canning, Robert J. Soiffer, MD, Jerome Ritz, MD, Nir Hacohen, PhD, Haesook T Kim, PhD, Edwin P Alyea, III, MD, Catherine J Wu, MD

Blood (2012) 120 (21): 1903.

https://doi.org/10.1182/blood.V120.21.1903.1903

Published: 2012

Journal Articles

Somatic Mutation As a Mechanism of Wnt/β-Catenin Pathway Activation in CLL

Lili Wang, M.D., Ph.D., Alex K Shalek, Ph.D., Jellert Gaublomme, Michael Lawrence, Ph.D., Kristen E. Stevenson, MS, Donna S. Neuberg, ScD, Nir Hacohen, PhD, Gad Getz, Ph.D., Jennifer R. Brown, MD, PhD, Hongkun Park, Ph.D., Catherine J. Wu, MD

Blood (2012) 120 (21): 559.

https://doi.org/10.1182/blood.V120.21.559.559

Published: 2012

Journal Articles

Systematic Identification of Personal Mutated Tumor-Specific Neoantigens in CLL

Mohini Rajasagi, PhD, Derin Keskin, MD PhD, Jintaek Kim, PhD, Wandi Zhang, Sachet Shukla, David DeLuca, PhD, John Sidney, PhD, Vladimir Brusic, PhD, Donna S. Neuberg, ScD, Gad Getz, PhD, Eric S. Lander, PhD, Nir Hacohen, PhD, Catherine J. Wu, MD

Blood (2012) 120 (21): 954.

https://doi.org/10.1182/blood.V120.21.954.954

Published: 2012

Journal Articles

Shifts in Intra-Clonal Dynamics Rather Than Novel Mutations Are the Main Engine Driving Tumor Evolution in Relapsed CLL

Dan-Avi Landau, MD, Petar Stojanov, Michael S Lawrence, Carrie Sougnez, Aaron McKeena, Scott Carter, Stacey Gabriel, Donna Neuberg, ScD, Nir Hacohen, Eric S Lander, Jennifer R. Brown, MD, PhD, Gad Getz, Cathy Wu

Blood (2011) 118 (21): 284.

https://doi.org/10.1182/blood.V118.21.284.284

Published: 2011

Journal Articles

Sensitivity to Wnt Pathway Inhibition in CLL Is Associated with Specific Gene Expression Signatures

Lili Wang, Alex K Shalek, Jellert Gaublomme, Nir Yosef, Jennifer R Brown, MD, PhD, Donna Neuberg, ScD, Nir Hacohen, Hongkun Park, Catherine J Wu, MD

Blood (2011) 118 (21): 801.

https://doi.org/10.1182/blood.V118.21.801.801

Published: 2011

Journal Articles

Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1

Blood (2011) 118 (21): 463.

https://doi.org/10.1182/blood.V118.21.463.463

Published: 2011

Journal Articles

Whole Genome Sequencing Identifies Functional Mutations In the Wnt Pathway In CLL

Lili Wang, Nathalie Pochet, Kristian Cibulskis, Wandi Zhang, Mike Lawrence, Quinlan L. Sievers, Erica Shefler, Donna Neuberg, ScD, Stacey Gabriel, Carrie Sougnez, Aviv Regev, Gad Getz, Nir Hacohen, Jennifer R Brown, MD, PhD, Catherine J Wu, MD

Blood (2010) 116 (21): 693.

https://doi.org/10.1182/blood.V116.21.693.693

Published: 2010

Journal Articles

Forward RNAi screens in primary human hematopoietic stem/progenitor cells

Nicole Ali, Christine Karlsson, Marie Aspling, Guang Hu, Nir Hacohen, David T. Scadden, Jonas Larsson

Blood (2009) 113 (16): 3690–3695.

https://doi.org/10.1182/blood-2008-10-176396

Published: 2009

Includes: Supplemental data

NARROW

A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Harbors Frequent Splicesosome Mutations That Cause Aberrant RNA Splicing Affecting Genes Critical in pDC Differentiation and Function

Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program

Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion

Tumor Neoantigens Are Abundant Across Cancers

Reconstructing a Genotype-Phenotype Map In Chronic Lymphocytic Leukemia

Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution

Reversal of T Cell Exhaustion in Pre-Treatment Marrow T Cells Is Associated with Effective Graft-Versus-Leukemia Responses to Donor Lymphocyte Infusion

Somatic Mutation As a Mechanism of Wnt/β-Catenin Pathway Activation in CLL

Systematic Identification of Personal Mutated Tumor-Specific Neoantigens in CLL

Shifts in Intra-Clonal Dynamics Rather Than Novel Mutations Are the Main Engine Driving Tumor Evolution in Relapsed CLL

Sensitivity to Wnt Pathway Inhibition in CLL Is Associated with Specific Gene Expression Signatures

Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1

Whole Genome Sequencing Identifies Functional Mutations In the Wnt Pathway In CLL

Forward RNAi screens in primary human hematopoietic stem/progenitor cells

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American Society of Hematology

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American Society of Hematology

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