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Molecular monitoring during dose reduction predicts recurrence after TKI cessation in CML

Clinical Trials & Observations
Andrea Gottschalk, Ingmar Glauche, Silvia Cicconi, Richard E. Clark, Ingo Roeder
Journal: Blood
Blood (2020) 135 (10): 766–769.
https://doi.org/10.1182/blood.2019003395
Published: 2020
Includes: Supplemental data
Journal Articles

Response to Front-Line Imatinib Treatment in Children and Adolescents with CML - Data from a Large Pediatric Cohort

Meinolf Suttorp, MD PhD, Philipp Schulze, Ingmar Glauche, PhD, Gudrun Göhring, MD, Nils Von Neuhoff, PhD, Markus Metzler, MD, Petr Sedlacek, MD, Eveline S. de Bont, MD, Adriana Balduzzi, MD, Birgitte Lausen, MD, Olga Aleinikova, MD PhD, Sabina Sufliarska, MD, Guenter Henze, MD PhD, Gabriele Strauss, MD, Angelika Eggert, MD PhD, Bernhard Kremens, MD PhD, Andreas H Groll, MD PhD, Frank Berthold, MD PhD, Christoph Klein, MD PhD, Ute Gross-Wieltsch, MD, Karl-Walter Sykora, MD, Arndt Borkhardt, Prof MD, Andreas E. Kulozik, MD PhD, Martin Schrappe, MD PhD, Christina Nowasz, Manuela Krumbholz, PhD, Josephine Tabea Tauer, PhD, Alexander Claviez, MD, Jochen Harbott, PhD, Hans H Kreipe, MD PhD, Brigitte Schlegelberger, Prof. Dr., Christian Thiede, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 898.
https://doi.org/10.1182/blood.V130.Suppl_1.898.898
Published: 2017
Journal Articles

A New Computational Method to Predict Long-Term Minimal Residual Disease and Molecular Relapse after TKI-Cessation in CML

Ingmar Glauche, PhD, Hendrik Liebscher, Christoph Baldow, Matthias Kuhn, Philipp Schulze, Tom Haehnel, Astghik Voskanyan, PhD, Joelle Guilhot, PhD, Stéphanie Dulucq, PhD, Nikolas von Bubnoff, MD, Susanne Saussele, MD, Satu Mustjoki, MD PhD, Philipp J. Jost, MD, Francois Guilhot, MD PhD, François-Xavier Mahon, MD PhD, Ingo Roeder, PhD
Journal: Blood
Blood (2016) 128 (22): 3099.
https://doi.org/10.1182/blood.V128.22.3099.3099
Published: 2016
Journal Articles

Impact of Long-Term Tyrosine Kinase Inhibitor Exposure on Spermatogenesis in Juvenile Rats

Vera Girke, Josephine Tabea Tauer, PhD, Ingmar Glauche, PhD, Lorenz Hofbauer, MD PhD, Meinolf Suttorp, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1884.
https://doi.org/10.1182/blood.V128.22.1884.1884
Published: 2016
Journal Articles

Changes in Bone Metabolic Parameters Under Imatinib Treatment in Children with Chronic Myeloid Leukemia (CML)

Josephine Tabea Tauer, PhD, Ingmar Glauche, PhD, Meinolf Suttorp, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1574.
https://doi.org/10.1182/blood.V126.23.1574.1574
Published: 2015
Journal Articles

Model-Based Characterization of the Molecular Response Dynamics of Tyrosine Kinase Inhibitor (TKI)-Treated CML Patients – a Comparison of Imatinib and Dasatinib First-Line Therapy

Ingmar Glauche, Christoph Baldow, Sabine Fröhlich, Philipp Schulze, Amit Roy, Milayna Subar, Xiaoning Wang, Ingo Roeder, MD
Journal: Blood
Blood (2014) 124 (21): 4562.
https://doi.org/10.1182/blood.V124.21.4562.4562
Published: 2014
Journal Articles

Mathematical Modelling Of The Molecular BCR-ABL1 Transcript Response In Chronic Myeloid Leukemia: A Comparison Of Adult and Pediatric Patients

Rick Proschmann, Meinolf Suttorp, Andreas Hochhaus, MD, Christian Thiede, MD, Ingo Roeder, Ingmar Glauche
Journal: Blood
Blood (2013) 122 (21): 2709.
https://doi.org/10.1182/blood.V122.21.2709.2709
Published: 2013
Journal Articles

Scoring Systems For Predicting Outcome Of Chronic Myeloid Leukemia In Adults Are Poorly Informative In Pediatric Patients Treated With Imatinib

Meinolf Suttorp, Ingmar Glauche, David Gurrea Salas, Josephine Tabea Tauer, Christina Nowasz, Christian Thiede, MD
Journal: Blood
Blood (2013) 122 (21): 2725.
https://doi.org/10.1182/blood.V122.21.2725.2725
Published: 2013
Journal Articles

Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia

Clinical Trials & Observations
Matthias Horn, Ingmar Glauche, Martin C. Müller, Rüdiger Hehlmann, Andreas Hochhaus, Markus Loeffler, Ingo Roeder
Journal: Blood
Blood (2013) 121 (2): 378–384.
https://doi.org/10.1182/blood-2012-07-441956
Published: 2013
Includes: Supplemental data
Journal Articles

Modeling BCR-ABL Transcript Dynamics in CML Patients under Imatinib Treatment.

Ingo Roeder, PhD, Matthias Horn, Ingmar Glauche, Andreas Hochhaus, MD, Martin C. Mueller, MD, Markus Loeffler, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 2155.
https://doi.org/10.1182/blood.V108.11.2155.2155
Published: 2006