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Journal Articles

Application of Next-Generation Cytogenetics in a Clinical Laboratory for Diagnostic Work-up of Myelodysplastic Syndromes/Neoplasms (MDS)

Anindita Ghosh, Guilin Tang, Hui Yang, Koji Sasaki, Gokce A. Toruner, Juan Jose Rodriguez-Sevilla, Raja Luthra, Danielle Hammond, L. Jeffrey Medeiros, Carlos E. Bueso-Ramos, Guillermo Montalban-Bravo, Kelly S. Chien, Guillermo Garcia-Manero, Rashmi Kanagal-Shamanna

Blood (2024) 144 (Supplement 1): 7519.

https://doi.org/10.1182/blood-2024-211967

Published: 2024

Journal Articles

An Integrated Spatial, Codex, and Genomic Analysis Predicts Responsiveness and Survival in the Phase II Combination of Pembrolizumab and Romidepsin in PTCL

Ranjit Nair, Daniela E. Duenas, Jingjing Liu, Rishab Prakash, Chen Zhou, Ayse A Koksoy, Jie Xu, Salome A McAllen, Luis Malpica, Raja Luthra, Francisco Vega, Roberto N. Miranda, Jianhua Zhang, L. Jeffrey Medeiros, Cara L Haymaker, Christopher R. Flowers, Sattva S. Neelapu, Swami P. Iyer

Blood (2024) 144 (Supplement 1): 455.

https://doi.org/10.1182/blood-2024-211900

Published: 2024

Journal Articles

Genomic Profiling of T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) for Identification of Driver Aberrations Using Combined Next Generation Sequencing and Optical Genome Mapping in Clinical Diagnostic Laboratory

Iman Sarami, Ruchi Singhal, Mark Routbort, Koji Sasaki, Daniel Domogala III, Gokce A. Toruner, Shibu Ninan, Nitin Jain, Keyur P. Patel, Elias Jabbour, Hagop M. Kantarjian, Carlos E. Bueso-Ramos, L. Jeffrey Medeiros, Raja Luthra, Guilin Tang, Rashmi Kanagal-Shamanna

Blood (2024) 144 (Supplement 1): 4224.

https://doi.org/10.1182/blood-2024-211561

Published: 2024

Journal Articles

Clinical and Prognostic Implications of WT1 Mutations in De Novo and Relapsed Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 959.

https://doi.org/10.1182/blood-2023-188319

Published: 2023

Journal Articles

RAS and TP53 , Not NOTCH1 , Can Predict Survival in Adults with Acute T-Cell Lymphoblastic Leukemia Treated with Hypercvad

Ali Sakhdari, MD MSc, Sanam Loghavi, MD, Rashmi Kanagal-Shamanna, MD, C. Cameron Yin, MD PhD, Zhuang Zuo, MD, Mark Routbort, MD PhD, Keyur P. Patel, MBBS, PhD, Raja Luthra, PhD, L. Jeffrey Medeiros, MD, Chi Young Ok, MD

Blood (2018) 132 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2018-99-119017

Published: 2018

Journal Articles

Correlation of Mutational Profile and Response in Patients with Polycythemia Vera and Essential Thrombocythemia Treated with Pegylated Interferon Alfa 2a As Part of a Prospective Phase II Study

Lucia Masarova, MD, Keyur Patel, MD PhD, Saradhi Mallampathi, PhD, Yawa Dzifa Duose, PhD, Kate J Newberry, PhD, Jorge E. Cortes, MD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Raja Luthra, Srdan Verstovsek, MD PhD

Blood (2017) 130 (Supplement 1): 1640.

https://doi.org/10.1182/blood.V130.Suppl_1.1640.1640

Published: 2017

Journal Articles

Early Maintenance with Tyrosine Kinase Inhibitors Post Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Improves Survival in Ph+ Acute Lymphoblastic Leukemia (ALL) Patients

Blood (2017) 130 (Supplement 1): 1992.

https://doi.org/10.1182/blood.V130.Suppl_1.1992.1992

Published: 2017

Journal Articles

Standardized Targeted Sequencing of 29 Genes with Recurrent Mutations in Chronic Lymphocytic Leukemia (CLL) Helps to Better Define Clinical Correlates and Genomic Hotspots

Blood (2017) 130 (Supplement 1): 4304.

https://doi.org/10.1182/blood.V130.Suppl_1.4304.4304

Published: 2017

Journal Articles

Clonal chromosomal abnormalities appearing in Philadelphia chromosome–negative metaphases during CML treatment

Ghayas C. Issa, Hagop M. Kantarjian, Graciela Nogueras Gonzalez, Gautam Borthakur, Guilin Tang, William Wierda, Koji Sasaki, Nicholas J. Short, Farhad Ravandi, Tapan Kadia, Keyur Patel, Raja Luthra, Alessandra Ferrajoli, Guillermo Garcia-Manero, Mary Beth Rios, Sara Dellasala, Elias Jabbour, Jorge E. Cortes

Blood (2017) 130 (19): 2084–2091.

https://doi.org/10.1182/blood-2017-07-792143

Published: 2017

Includes: Supplemental data

Journal Articles

Validation of the 2016 Revision to the World Health Organization (WHO) Classification of Myelodysplastic Syndromes with Diploid Karyotype

Rashmi Kanagal-Shamanna, MD, Juliana E. Hidalgo Lopez, MD, Hye Ryoun Kim, MD PhD, Zhuang Zuo, MD PhD, Michelle Janania Martinez, Chong Zhao, MD PhD MS, Denái R. Milton, Francesco Stingo, PhD, John Lee, MD PhD, Raja Luthra, PhD, Keyur P. Patel, MD PhD, Elias J. Jabbour, MD, Guillermo Garcia-Manero, MD, L. Jeffrey Medeiros, MD, Carlos E Bueso-Ramos, MD PhD

Blood (2016) 128 (22): 4319.

https://doi.org/10.1182/blood.V128.22.4319.4319

Published: 2016

Journal Articles

Value of Immunohistochemistry-Based Direct Visualization for Localization, Lineage Determination and Monitoring of IDH1 p.R132H Mutant Clones in AML

Habibe Kurt, MD, Carlos E. Bueso-Ramos, MD PhD, Joseph D Khoury, MD, Mark Routbort, MD PhD, Rashmi Kanagal-Shamanna, MD, Jeffrey L. Jorgensen, MD PhD, Courtney D DiNardo, MD, Farhad Ravandi, MD, Hagop M. Kantarjian, MD, Raja Luthra, PhD, Jeffrey Medeiros, MD, Keyur Patel, MD

Blood (2016) 128 (22): 1726.

https://doi.org/10.1182/blood.V128.22.1726.1726

Published: 2016

Journal Articles

Routine Clinical Testing for Actionable Mutations in CLL Using Endcll Assay V1: The Initial MD Anderson Experience

Keyur P. Patel, MD PhD, Rajesh Singh, PhD, Mark Routbort, MD PhD, C. Cameron Yin, MD PhD, Rashmi Kanagal Shamanna, PhD, Nitin Jain, MD, Xinyan Lu, MD, Sherry Pierce, BSN, BA, Michael Keating, MBBS, Hagop M. Kantarjian, MD, L. Jeffrey Medeiros, MD, Raja Luthra, PhD, William G. Wierda, MD PhD

Blood (2016) 128 (22): 3196.

https://doi.org/10.1182/blood.V128.22.3196.3196

Published: 2016

Journal Articles

Clinical Implications of TP53 Mutations in Adult Patients with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) Treated with the Hypercvad-Based Regimens

Blood (2016) 128 (22): 2917.

https://doi.org/10.1182/blood.V128.22.2917.2917

Published: 2016

Journal Articles

Mutation Analysis in 276 Cases of Newly Diagnosed Acute Myeloid Leukemia By Next Generation Sequencing: Association with Established Prognostic Variables and MRC Risk Groups

Parsa Hodjat, MD, Kankana Ghosh, B. Pharm, Priyanka Priyanka, MPH, Beenu Thakral, MBBS,MD, Keyur P. Patel, MD PhD, Mark Routbort, MD PhD, Rashmi Kanagal-Shamana, MD, C. Cameron Yin, MDPhD, Zhuang Zuo, MD PhD, Raja Luthra, PhD, Tariq Muzzafar, MD

Blood (2015) 126 (23): 1392.

https://doi.org/10.1182/blood.V126.23.1392.1392

Published: 2015

Journal Articles

Impact of the Type of BCR-ABL Fusion Transcripts on Response and Survival in Patients with Chronic Phase CML Treated with Four Frontline TKI Modalities

Preetesh Jain, MBBS,MDDM,PhD, Hagop M. Kantarjian, MD, Raja Luthra, PhD, Graciela Nogueras Gonzalez, Elias Jabbour, Koji Sasaki, MD, Carlos Guillermo Romo, MD, Keyur P. Patel, MD PhD, Tapan Kadia, MD, Gautam Borthakur, MD, Zeev Estrov, MD, Farhad Ravandi, MD, Susan O'Brien, MD, Jorge E. Cortes, MD

Blood (2015) 126 (23): 598.

https://doi.org/10.1182/blood.V126.23.598.598

Published: 2015

Journal Articles

RAS/RAF Pathway Mutations Define a Distinct Subset of Chronic Lymphocytic Leukemia

Rashmi Kanagal-Shamanna, MD, Raja Luthra, PhD, Madan Luthra, PhD, Xinyan Lu, MD, Mark Routbort, MD PhD, Nitin Jain, MD, Michael Keating, MBBS, L Jeffrey Medeiros, MD, William Wierda, MD PhD, Keyur P. Patel, MD PhD

Blood (2015) 126 (23): 1730.

https://doi.org/10.1182/blood.V126.23.1730.1730

Published: 2015

Journal Articles

Qualitative and Quantitative Correlation of PML-Rara Fusion Transcript from Peripheral Blood and Bone Marrow Samples By Quantitative Real-Time PCR in Patients with Acute Promyelocytic Leukemia

Koji Sasaki, MD, Hagop M. Kantarjian, MD, Raja Luthra, PhD, Keyur P. Patel, MD PhD, Guillermo Garcia-Manero, MD, Srdan Verstovsek, MD PhD, Elihu H. Estey, MD, Tapan Kadia, MD, Mark Brandt, BS, Sherry Pierce, BSN, BA, Zeev Estrov, MD, Alessandra Ferrajoli, MD, Gautam Borthakur, MD, Jorge E. Cortes, MD, Farhad Ravandi, MD

Blood (2015) 126 (23): 3756.

https://doi.org/10.1182/blood.V126.23.3756.3756

Published: 2015

Journal Articles

Mutation Analysis in 200 Cases of Newly Diagnosed Myelodysplastic Syndrome By Next Generation Sequencing: Association with Established Prognostic Variables and IPSS-R

Kankana Ghosh, B. Pharm, Parsa Hodjat, MD, Priyanka Priyanka, MPH, Beenu Thakral, MBBS,MD, Keyur P. Patel, MD PhD, Mark Routbort, MD PhD, Rashmi Kanagal-Shamana, MD, C. Cameron Yin, MDPhD, Zhuang Zuo, MD PhD, Raja Luthra, PhD, Tariq Muzzafar, MD

Blood (2015) 126 (23): 1703.

https://doi.org/10.1182/blood.V126.23.1703.1703

Published: 2015

Journal Articles

Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with CALR mutation and BCR-ABL1

Sanam Loghavi, Naveen Pemmaraju, Rashmi Kanagal-Shamanna, Meenakshi Mehrotra, L. Jeffrey Medeiros, Raja Luthra, Pei Lin, Yang Huh, Hagop M. Kantarjian, Jorge E. Cortes, Srdan Verstovsek, Keyur P. Patel

Blood (2015) 125 (21): 3360–3363.

https://doi.org/10.1182/blood-2015-03-632893

Published: 2015

Journal Articles

Multigene Mutational Clinical Profiling Using Next Generation Sequencing in a Cohort of 451 Patients with MDS: Impact on Clinical Outcomes

Blood (2014) 124 (21): 4658.

https://doi.org/10.1182/blood.V124.21.4658.4658

Published: 2014

NARROW

Application of Next-Generation Cytogenetics in a Clinical Laboratory for Diagnostic Work-up of Myelodysplastic Syndromes/Neoplasms (MDS)

An Integrated Spatial, Codex, and Genomic Analysis Predicts Responsiveness and Survival in the Phase II Combination of Pembrolizumab and Romidepsin in PTCL

Genomic Profiling of T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) for Identification of Driver Aberrations Using Combined Next Generation Sequencing and Optical Genome Mapping in Clinical Diagnostic Laboratory

Clinical and Prognostic Implications of WT1 Mutations in De Novo and Relapsed Acute Myeloid Leukemia

RAS and TP53 , Not NOTCH1 , Can Predict Survival in Adults with Acute T-Cell Lymphoblastic Leukemia Treated with Hypercvad

Correlation of Mutational Profile and Response in Patients with Polycythemia Vera and Essential Thrombocythemia Treated with Pegylated Interferon Alfa 2a As Part of a Prospective Phase II Study

Early Maintenance with Tyrosine Kinase Inhibitors Post Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Improves Survival in Ph+ Acute Lymphoblastic Leukemia (ALL) Patients

Standardized Targeted Sequencing of 29 Genes with Recurrent Mutations in Chronic Lymphocytic Leukemia (CLL) Helps to Better Define Clinical Correlates and Genomic Hotspots

Clonal chromosomal abnormalities appearing in Philadelphia chromosome–negative metaphases during CML treatment

Validation of the 2016 Revision to the World Health Organization (WHO) Classification of Myelodysplastic Syndromes with Diploid Karyotype

Value of Immunohistochemistry-Based Direct Visualization for Localization, Lineage Determination and Monitoring of IDH1 p.R132H Mutant Clones in AML

Routine Clinical Testing for Actionable Mutations in CLL Using Endcll Assay V1: The Initial MD Anderson Experience

Clinical Implications of TP53 Mutations in Adult Patients with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) Treated with the Hypercvad-Based Regimens

Mutation Analysis in 276 Cases of Newly Diagnosed Acute Myeloid Leukemia By Next Generation Sequencing: Association with Established Prognostic Variables and MRC Risk Groups

Impact of the Type of BCR-ABL Fusion Transcripts on Response and Survival in Patients with Chronic Phase CML Treated with Four Frontline TKI Modalities

RAS/RAF Pathway Mutations Define a Distinct Subset of Chronic Lymphocytic Leukemia

Qualitative and Quantitative Correlation of PML-Rara Fusion Transcript from Peripheral Blood and Bone Marrow Samples By Quantitative Real-Time PCR in Patients with Acute Promyelocytic Leukemia

Mutation Analysis in 200 Cases of Newly Diagnosed Myelodysplastic Syndrome By Next Generation Sequencing: Association with Established Prognostic Variables and IPSS-R

Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with CALR mutation and BCR-ABL1

Multigene Mutational Clinical Profiling Using Next Generation Sequencing in a Cohort of 451 Patients with MDS: Impact on Clinical Outcomes

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American Society of Hematology

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American Society of Hematology

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