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Journal Articles

High Leukemic Stem Cell Frequency in FLT3-Mutated Acute Myeloid Leukemia Patients with Normal Karyotype: Implications for Prognosis

Camila Araújo Bernardino Garcia, Leticia Olops Marini, Mariana Medeiros, Amanda Fernandes Oliveira Costa, Maria Isabel Ayrosa, Katia B Pagnano, Elenaide Nunes, Ana Beatriz F Gloria, Priscila Santos Scheucher, Josiane Lillian Schiavinato, Eduardo M. Rego, Fabiola Traina, Lorena Lobo Figueiredo-Pontes

Blood (2024) 144 (Supplement 1): 6147.

https://doi.org/10.1182/blood-2024-209775

Published: 2024

Journal Articles

Synergistic Effect of Tamoxifen and Ruxolitinib Combination in Reducing Disease Burden in Myeloproliferative Neoplasms

Diego A Pereira-Martins, Antonio Bruno Alves-Silva, Manuela Albuquerque De Melo, Natasha Peixoto Fonseca, Isabel Weinhäuser, Fabio Augusto Bueno Perez, Artur Bernardo Ribeiro Bellomi, Lorena Lobo Figueiredo-Pontes, João Agostinho Machado-Neto, Lynn Quek, Prodromos Chatzikyriakou, Gerwin A. Huls, Emanuele Ammatuna, Jan Jacob Schuringa, Fabiola Traina

Blood (2024) 144 (Supplement 1): 4518.

https://doi.org/10.1182/blood-2024-209823

Published: 2024

Journal Articles

Molecular Mechanisms Associated with Autophagy Inhibition to Overcome Resistance to FLT3 Inhibitors

Manuela Albuquerque De Melo, Diego A. Pereira-Martins, Brunno Gilberto Santos Macedo, Livia Bassani Lins de Miranda, Priscila Santos Scheucher, Isabel Weinhäuser, Gerwin Huls, Jan Jacob Schuringa, João Agostinho Machado-Neto, Fabiola Traina

Blood (2024) 144 (Supplement 1): 2752.

https://doi.org/10.1182/blood-2024-203390

Published: 2024

Journal Articles

Clinical networking results in continuous improvement of the outcome of patients with acute promyelocytic leukemia

Blood (2024) 144 (12): 1257–1270.

https://doi.org/10.1182/blood.2024023890

Published: 2024

Includes: Supplemental data

Journal Articles

Autophagy Induction Constitutes a Targetable Vulnerability in FLT3-Mutant Acute Myeloid Leukemia Cells Treated with FLT3-Inhibitors

Manuela Albuquerque de Melo, Brunno Gilberto Santos Macedo, Natasha Peixoto Fonseca, Priscila Santos Scheucher, Diego A Pereira-Martins, João Agostinho Machado-Neto, Fabiola Traina

Blood (2023) 142 (Supplement 1): 5752.

https://doi.org/10.1182/blood-2023-190724

Published: 2023

Journal Articles

Microcosting Analysis of Hematopoietic Stem Cell Transplantation and Chemotherapy with Intermediate Doses of Cytarabine in the Treatment of Acute Myeloid Leukemia

Sitania Chiesa, Maria Isabel Ayrosa, Lorena Lobo Figueiredo-Pontes, Fabiola Traina, Leticia Olops Marani, Vanessa Teich, Eduardo Magalhães Rego

Blood (2023) 142 (Supplement 1): 7286.

https://doi.org/10.1182/blood-2023-181852

Published: 2023

Journal Articles

Metabolism-Related Features Identify the Combination Metformin Plus NAMPT Inhibitors As a Selective Treatment Strategy in Acute Myeloid Leukemia

Isabel Weinhaeuser, Diego Pereira-Martins, Dominique Sternadt, Emmanuel F Griessinger, Douglas RA Silveira, Juan L Coelho-Silva, Antonio Bruno Alves-Silva, Ayşegül Erdem, Bruno Koza Lino Duarte, Lynn Quek, Fabiola Traina, Sara Teresinha Olalla Saad, Jacobien R Hilberink, Emanuele Ammatuna, Eduardo Magalhães Rego, Geert A. Huls, Antonio R Lucena-Araujo, Jan Jacob Schuringa

Blood (2023) 142 (Supplement 1): 294.

https://doi.org/10.1182/blood-2023-186061

Published: 2023

Journal Articles

External Validation of the Advanced-Stage Hodgkin Lymphoma International Prognostic Index (A-HIPI): Strong Calibration in the Brazilian Prospective Hodgkin Lymphoma Registry

Blood (2023) 142 (Supplement 1): 6200.

https://doi.org/10.1182/blood-2023-173318

Published: 2023

Journal Articles

Real-World Data for FLT3-Mutated Acute Myeloid Leukemia Patients Treated in Resource-Constrained Settings

Wellington F Silva, Fernanda Rodrigues Mendes, Marco Sartori, Maria Isabel A Madeira, Katia B Pagnano, Ana Beatriz F Gloria, Elenaide C. Nunes, Luciana Nardinelli, Rita De Cássia Cavaglieri Medeiros, Israel Bendit, Fabiola Traina, Bruno Kosa Lino Duarte, Lorena Lobo Figueiredo-Pontes, Vanderson Rocha, Elvira Deolinda Rodrigues Pereira Velloso, Eduardo Magalhães Rego

Blood (2023) 142 (Supplement 1): 5839.

https://doi.org/10.1182/blood-2023-187902

Published: 2023

Journal Articles

Feasibility and Relevance of Incorporating Genetic Testing By Next-Generation Sequencing for Acute Myeloid Leukemia Patients Treated in Low- and Middle-Income Countries

Blood (2023) 142 (Supplement 1): 2929.

https://doi.org/10.1182/blood-2023-189806

Published: 2023

Journal Articles

High MN1 Expression Is Associated with an Lspc-Enriched Phenotype and Glycolysis Representing a New Vulnerability in Acute Myeloid Leukemia

Diego Pereira-Martins, Noortje van Dijk, Isabel Weinhaeuser, Douglas RA Silveira, Juan Coelho Da Silva, Thiago M Bianco, César Alexander Ortiz, Fabiola Traina, Lorena L Figueiredo-Pontes, Emanuele Ammatuna, Lynn Quek, Gerwin A. Huls, Antonio R. Lucena-Araujo, Eduardo M Rego, Jan Jacob Schuringa

Blood (2022) 140 (Supplement 1): 6265–6266.

https://doi.org/10.1182/blood-2022-165151

Published: 2022

Journal Articles

Dysregulated Activating and Inhibitory Receptors on Natural Killer Cells Predicts Immune Escape and Poor Outcomes in Acute Myeloid Leukemia

Amanda F O Costa, Valeriya Kuznetsova, Leticia O Marani, Izabela A Lopes, Larissa S Binelli, Priscila S Scheucher, Josiane L Schiavinato, Joana T B Faria, Maria Isabel A Madeira, Katia B Pagnano, Bruno K Duarte, Ana Beatriz F Gloria, Eduardo M Rego, Fabiola Traina, Robert Welner, Lorena L Figueiredo-Pontes

Blood (2022) 140 (Supplement 1): 9113–9114.

https://doi.org/10.1182/blood-2022-168178

Published: 2022

Journal Articles

Metformin Inhibits STAT3 and MAPK Signaling through AMPK Activation in CSF3R T618I Cells

Natasha Peixoto Fonseca, Bruna Alves Fenerich, Diego A Pereira-Martins, Pedro Manoel Marques Garibaldi, Juan L Coelho-Silva, Antonio Bruno Alves Silva, Jaqueline Cristina Fernandes, Cleide Lucia Silva, Eduardo M Rego, João Agostinho Machado-Neto, Fabiola Traina

Blood (2022) 140 (Supplement 1): 12153–12154.

https://doi.org/10.1182/blood-2022-167392

Published: 2022

Journal Articles

Final Results of the Fibromet Trial: An Open Label Phase II Study to Evaluate Metformin Effects on Bone Marrow Fibrosis and Disease Progression in Primary Myelofibrosis Patients

Paula De Melo Campos, Katia B Pagnano, Rubia Isler Mancuso, Fernanda Isabel Della Via, Ângela Condotta Tinoco, Guilherme Rossi Assis-Mendonça, Leandro Luiz Lopes Freitas, Fabiola Traina, Sara T Olalla Saad

Blood (2021) 138 (Supplement 1): 2584.

https://doi.org/10.1182/blood-2021-151077

Published: 2021

Journal Articles

IGF1R-IRS1/2 Pharmacological Inhibitors Act By Distinct Cellular and Molecular Mechanisms and Reveals Vulnerabilities for Treatment of Acute Myeloid Leukemia

Juan L Coelho-Silva, Diego A Pereira-Martins, Virginia Campos Silvestrini, João Agostinho Machado-Neto, Eduardo M Rego, Marcus Smolka, Vitor Marcel Faca, Fabiola Traina

Blood (2021) 138 (Supplement 1): 1869.

https://doi.org/10.1182/blood-2021-153105

Published: 2021

Journal Articles

Irs1 S57X Heterozygous Mutant Mice Display Normal Hematopoiesis and Phenotypic Features, While Homozygous Knockout Exhibit High Fetal or Postnatal Lethality

Bruna Alves Fenerich, BSc, Jaqueline Cristina Fernandes, BSc, MSc, Cleide Lúcia Araújo Silva, MSc, Juan L Coelho-Silva, BSc, MSc, Antonio Bruno Alves Silva, BSc, MSc, Natasha Peixoto Fonseca, B.Sc., M.Sc., João Agostinho Machado-Neto, PhD, Fabiola Traina, MD PhD

Blood (2020) 136 (Supplement 1): 33–34.

https://doi.org/10.1182/blood-2020-139422

Published: 2020

Journal Articles

Cytopenia Management in Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Venetoclax Plus Azacitidine in the VIALE-A Study

Blood (2020) 136 (Supplement 1): 51–53.

https://doi.org/10.1182/blood-2020-134832

Published: 2020

Journal Articles

Co-occurrence of DNMT3A , NPM1 , FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis

Blood (2020) 135 (11): 870–875.

https://doi.org/10.1182/blood.2019003339

Published: 2020

Includes: Supplemental data

Journal Articles

Analysis of Metformin Effects on Bone Marrow Fibrosis and Disease Progression in Primary Myelofibrosis Patients: Preliminary Results of an Open Label Phase II Trial (FIBROMET)

Paula De Melo Campos, MD, Katia B Pagnano, MD PhD, Rubia Mancuso, Francisco Breno S. Teófilo, Juan L Coelho-Silva, BSc, MSc, Fernanda I Della Via, MSc, Leandro Luiz Lopes Freitas, MD PhD, Hernandes F. Carvalho, PhD, Fernando Ferreira Costa, MD PhD, Fabiola Traina, MD PhD, Sara T Olalla Saad, PhD

Blood (2019) 134 (Supplement_1): 554.

https://doi.org/10.1182/blood-2019-130648

Published: 2019

Journal Articles

Molecular-Based Score Inspired on Metabolic Signature Improves Prognostic Stratification for Myelodysplastic Syndrome

Juan L Coelho-Silva, BSc, MSc, Douglas R. A. Silveira, Diego A Pereira-Martins, MSc, César Alexander Ortiz Rojas, BSc, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD, João Agostinho Machado-Neto, PhD, Israel Bendit, MD PhD, Vanderson Rocha, MD PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 4257.

https://doi.org/10.1182/blood-2019-132141

Published: 2019

NARROW

High Leukemic Stem Cell Frequency in FLT3-Mutated Acute Myeloid Leukemia Patients with Normal Karyotype: Implications for Prognosis

Synergistic Effect of Tamoxifen and Ruxolitinib Combination in Reducing Disease Burden in Myeloproliferative Neoplasms

Molecular Mechanisms Associated with Autophagy Inhibition to Overcome Resistance to FLT3 Inhibitors

Clinical networking results in continuous improvement of the outcome of patients with acute promyelocytic leukemia

Autophagy Induction Constitutes a Targetable Vulnerability in FLT3-Mutant Acute Myeloid Leukemia Cells Treated with FLT3-Inhibitors

Microcosting Analysis of Hematopoietic Stem Cell Transplantation and Chemotherapy with Intermediate Doses of Cytarabine in the Treatment of Acute Myeloid Leukemia

Metabolism-Related Features Identify the Combination Metformin Plus NAMPT Inhibitors As a Selective Treatment Strategy in Acute Myeloid Leukemia

External Validation of the Advanced-Stage Hodgkin Lymphoma International Prognostic Index (A-HIPI): Strong Calibration in the Brazilian Prospective Hodgkin Lymphoma Registry

Real-World Data for FLT3-Mutated Acute Myeloid Leukemia Patients Treated in Resource-Constrained Settings

Feasibility and Relevance of Incorporating Genetic Testing By Next-Generation Sequencing for Acute Myeloid Leukemia Patients Treated in Low- and Middle-Income Countries

High MN1 Expression Is Associated with an Lspc-Enriched Phenotype and Glycolysis Representing a New Vulnerability in Acute Myeloid Leukemia

Dysregulated Activating and Inhibitory Receptors on Natural Killer Cells Predicts Immune Escape and Poor Outcomes in Acute Myeloid Leukemia

Metformin Inhibits STAT3 and MAPK Signaling through AMPK Activation in CSF3R T618I Cells

Final Results of the Fibromet Trial: An Open Label Phase II Study to Evaluate Metformin Effects on Bone Marrow Fibrosis and Disease Progression in Primary Myelofibrosis Patients

IGF1R-IRS1/2 Pharmacological Inhibitors Act By Distinct Cellular and Molecular Mechanisms and Reveals Vulnerabilities for Treatment of Acute Myeloid Leukemia

Irs1 S57X Heterozygous Mutant Mice Display Normal Hematopoiesis and Phenotypic Features, While Homozygous Knockout Exhibit High Fetal or Postnatal Lethality

Cytopenia Management in Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Venetoclax Plus Azacitidine in the VIALE-A Study

Co-occurrence of DNMT3A , NPM1 , FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis

Analysis of Metformin Effects on Bone Marrow Fibrosis and Disease Progression in Primary Myelofibrosis Patients: Preliminary Results of an Open Label Phase II Trial (FIBROMET)

Molecular-Based Score Inspired on Metabolic Signature Improves Prognostic Stratification for Myelodysplastic Syndrome

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American Society of Hematology

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American Society of Hematology

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