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Melissa Rijken
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Journal Articles

DNMT3A Mutations Deregulate the DNA Demethylation Pathway in Acute Myeloid Leukemia

Sanne Massaar, Emma Boertjes, Annelieke Zeilemaker, Jolinda Konijnenburg, Francois Kavelaars, Melissa Rijken, Tim Grob, Jurjen Versluis, Bob Lowenberg, Peter J. M. Valk, Mathijs Arnoud Sanders
Journal: Blood
Blood (2024) 144 (Supplement 1): 2718.
https://doi.org/10.1182/blood-2024-209821
Published: 2024
Journal Articles

Feasibility and Relevance of Incorporating Genetic Testing By Next-Generation Sequencing for Acute Myeloid Leukemia Patients Treated in Low- and Middle-Income Countries

Fabiola Traina, Lorena Lobo Figueiredo-Pontes, Maria Isabel Ayrosa, Katia B Pagnano, Ana Beatriz F Gloria, Elvira Deolinda Rodrigues Pereira Velloso, Elenaide C. Nunes, Marcia Higashi, Bruno Kosa Lino Duarte, Evandro M Fagundes, Wellington F Silva, Brunno Gilberto Santos Macedo, Rita de Cássia Cavaglieri Medeiros, Ana Sílvia Gouvêa Lima Yamada, Patricia C Ruy, Melissa Rijken, Bob Lowenberg, Torsten Haferlach, Arnold Ganser, Richard Dillon, Nancy Berliner, Peter J. M. Valk, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 2929.
https://doi.org/10.1182/blood-2023-189806
Published: 2023
Journal Articles

High-Throughput Proteomics Identifies THEMIS2 As Biomarker of Inferior Treatment-Free Survival in Chronic Lymphocytic Leukemia

Paul Hengeveld, Pieter M. Kolijn, Jeroen A.A. Demmers, Wouter Doff, Julie M.N. Dubois, Melissa Rijken, Jorn Assmann, Lina Van Der Straten, Henk-Jan Boiten, Kirsten J. Gussinklo, Peter J.M. Valk, Peter E. Westerweel, Arnon P. Kater, Anton W. Langerak, Mark-David Levin
Journal: Blood
Blood (2022) 140 (Supplement 1): 9851–9852.
https://doi.org/10.1182/blood-2022-158881
Published: 2022
Journal Articles

Molecular characterization of mutant TP53 acute myeloid leukemia and high-risk myelodysplastic syndrome

Tim Grob, Adil S. A. Al Hinai, Mathijs A. Sanders, François G. Kavelaars, Melissa Rijken, Patrycja L. Gradowska, Bart J. Biemond, Dimitri A. Breems, Johan Maertens, Marinus van Marwijk Kooy, Thomas Pabst, Okke de Weerdt, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht, Gerwin A. Huls, Jan J. Cornelissen, H. Berna Beverloo, Bob Löwenberg, Mojca Jongen-Lavrencic, Peter J. M. Valk
Journal: Blood
Blood (2022) 139 (15): 2347–2354.
https://doi.org/10.1182/blood.2021014472
Published: 2022
Includes: Supplemental data
Journal Articles

Archived Bone Marrow Smears Are an Excellent Source for NGS-Based Mutation Detection in Acute Myeloid Leukemia

Adil S.A. Al Hinai, MSc, Francois G. Kavelaars, Melissa Rijken, Tim Grob, MD, Kirsten Gussinklo, Annelieke Zeilemaker, Claudia Erpelinck-Verschueren, B.Sc., Mathijs A. Sanders, PhD, Kirsten van Lom, Peter J.M. Valk, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2783.
https://doi.org/10.1182/blood-2018-99-118066
Published: 2018
Journal Articles

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Mathijs A. Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E. Miller, Adil S. al Hinai, Ashish Bajel, Bram Luiken, Melissa Rijken, Tamara Mclennan, Remco M. Hoogenboezem, François G. Kavelaars, Stefan Fröhling, Marnie E. Blewitt, Eric M. Bindels, Warren S. Alexander, Bob Löwenberg, Andrew W. Roberts, Peter J. M. Valk, Ian J. Majewski
Journal: Blood
Blood (2018) 132 (14): 1526–1534.
https://doi.org/10.1182/blood-2018-05-852566
Published: 2018
Includes: Supplemental data
Journal Articles

DNMT3A Mutations Enhance CpG Mutagenesis through Deregulation of the Active DNA Demethylation Pathway

Mathijs A. Sanders, PhD, Annelieke Zeilemaker, Adil al Hinai, Remco Hoogenboezem, François G. Kavelaars, BSc, Melissa Rijken, Eric M.J. Bindels, PhD, Bob Löwenberg, MD PhD, Peter J.M. Valk, PhD
Journal: Blood
Blood (2016) 128 (22): 1076.
https://doi.org/10.1182/blood.V128.22.1076.1076
Published: 2016