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Lorena Lobo Figueiredo-Pontes
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Journal Articles

T-Cell Memory Compartment Downregulation and NK Cell Activation Are Associated with Myelofibrosis Progression

Mariana Medeiros, Camila Araújo Bernardino Garcia, Larissa Sarri Binelli, Allana Guimarães de Carvalho, Leticia Olops Marani, Priscila Santos Scheucher, Josiane Lillian Schiavinato, Leonardo Carvalho Palma, Pedro Manoel Marques Garibaldi, Robert Welner, Lorena Lobo Figueiredo-Pontes
Journal: Blood
Blood (2024) 144 (Supplement 1): 6582.
https://doi.org/10.1182/blood-2024-207246
Published: 2024
Journal Articles

High Leukemic Stem Cell Frequency in FLT3-Mutated Acute Myeloid Leukemia Patients with Normal Karyotype: Implications for Prognosis

Camila Araújo Bernardino Garcia, Leticia Olops Marini, Mariana Medeiros, Amanda Fernandes Oliveira Costa, Maria Isabel Ayrosa, Katia B Pagnano, Elenaide Nunes, Ana Beatriz F Gloria, Priscila Santos Scheucher, Josiane Lillian Schiavinato, Eduardo M. Rego, Fabiola Traina, Lorena Lobo Figueiredo-Pontes
Journal: Blood
Blood (2024) 144 (Supplement 1): 6147.
https://doi.org/10.1182/blood-2024-209775
Published: 2024
Journal Articles

Synergistic Effect of Tamoxifen and Ruxolitinib Combination in Reducing Disease Burden in Myeloproliferative Neoplasms

Diego A Pereira-Martins, Antonio Bruno Alves-Silva, Manuela Albuquerque De Melo, Natasha Peixoto Fonseca, Isabel Weinhäuser, Fabio Augusto Bueno Perez, Artur Bernardo Ribeiro Bellomi, Lorena Lobo Figueiredo-Pontes, João Agostinho Machado-Neto, Lynn Quek, Prodromos Chatzikyriakou, Gerwin A. Huls, Emanuele Ammatuna, Jan Jacob Schuringa, Fabiola Traina
Journal: Blood
Blood (2024) 144 (Supplement 1): 4518.
https://doi.org/10.1182/blood-2024-209823
Published: 2024
Journal Articles

Immune Content of Mature and Licensed Cytotoxic Cells Is Associated with Treatment-Free Remission in Chronic Myeloid Leukemia

Camila Araújo Bernardino Garcia, Larissa Sarri Binelli, Leonardo Carvalho Palma, Leticia Olops Marani, Mariana Medeiros, Allana Guimarães de Carvalho, Priscila Santos Scheucher, Josiane Lillian Schiavinato, Pedro Manoel Marques Garibaldi, Robert Welner, Fabíola Attié de Castro, Katia B Pagnano, Lorena Lobo Figueiredo-Pontes
Journal: Blood
Blood (2024) 144 (Supplement 1): 1756.
https://doi.org/10.1182/blood-2024-208109
Published: 2024
Journal Articles

Microcosting Analysis of Hematopoietic Stem Cell Transplantation and Chemotherapy with Intermediate Doses of Cytarabine in the Treatment of Acute Myeloid Leukemia

Sitania Chiesa, Maria Isabel Ayrosa, Lorena Lobo Figueiredo-Pontes, Fabiola Traina, Leticia Olops Marani, Vanessa Teich, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 7286.
https://doi.org/10.1182/blood-2023-181852
Published: 2023
Journal Articles

Jak2V617F Bone Marrow Exposure Leads to Dysfunction of Normal NK Cells

Izabela Aparecida Lopes, Camila Araújo Bernardino Garcia, Leticia Olops Marini, Amanda Fernandes Oliveira Costa, Larissa Sarri Binelli, Mariana Medeiros, Josiane Lillian Schiavinato, Priscila Santos Scheucher, Cleide Lúcia Araújo Silva, Lorena Lobo Figueiredo-Pontes
Journal: Blood
Blood (2023) 142 (Supplement 1): 3153.
https://doi.org/10.1182/blood-2023-189920
Published: 2023
Journal Articles

Real-World Data for FLT3-Mutated Acute Myeloid Leukemia Patients Treated in Resource-Constrained Settings

Wellington F Silva, Fernanda Rodrigues Mendes, Marco Sartori, Maria Isabel A Madeira, Katia B Pagnano, Ana Beatriz F Gloria, Elenaide C. Nunes, Luciana Nardinelli, Rita De Cássia Cavaglieri Medeiros, Israel Bendit, Fabiola Traina, Bruno Kosa Lino Duarte, Lorena Lobo Figueiredo-Pontes, Vanderson Rocha, Elvira Deolinda Rodrigues Pereira Velloso, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 5839.
https://doi.org/10.1182/blood-2023-187902
Published: 2023
Journal Articles

Feasibility and Relevance of Incorporating Genetic Testing By Next-Generation Sequencing for Acute Myeloid Leukemia Patients Treated in Low- and Middle-Income Countries

Fabiola Traina, Lorena Lobo Figueiredo-Pontes, Maria Isabel Ayrosa, Katia B Pagnano, Ana Beatriz F Gloria, Elvira Deolinda Rodrigues Pereira Velloso, Elenaide C. Nunes, Marcia Higashi, Bruno Kosa Lino Duarte, Evandro M Fagundes, Wellington F Silva, Brunno Gilberto Santos Macedo, Rita de Cássia Cavaglieri Medeiros, Ana Sílvia Gouvêa Lima Yamada, Patricia C Ruy, Melissa Rijken, Bob Lowenberg, Torsten Haferlach, Arnold Ganser, Richard Dillon, Nancy Berliner, Peter J. M. Valk, Eduardo Magalhães Rego
Journal: Blood
Blood (2023) 142 (Supplement 1): 2929.
https://doi.org/10.1182/blood-2023-189806
Published: 2023
Journal Articles

Reduced SLIT2 Are Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in APL Cells

Isabel Weinhäuser, MSc, Diego A Pereira-Martins, MSc, Luíse A A Simões, BSc, César Alexander Ortiz Rojas, BSc, Thiago Mantello Bianco, MSc, Cleide Lucia Silva, MSc, Mariane Cristina Do Nascimento, BSc, Lorena Lobo Figueiredo-Pontes, MD PhD, Antonio R. Lucena-Araujo, PhD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5165.
https://doi.org/10.1182/blood-2019-131496
Published: 2019
Journal Articles

The Scenario of Myelofibrosis in Brazil in the View of a Panel of Experts: Challenges and Proposals

Laura Maria Fogliatto, MD PhD, Cristiana Solza, MD PhD, Alexandre Gustavo Apa, MD, Gustavo HR Magalhaes, MD MSc, Marcia Torresan Delamain, MD, Renato Tavares, MD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5851.
https://doi.org/10.1182/blood-2019-121960
Published: 2019
Journal Articles

Experience of Generic Imatinib As a First Line Therapy for Patients with Chronic Myeloid Leukemia in a Single Reference Institution

Gabriel Carvalho Pereira, MD, Fernanda B da Silva, BSc and MSc, Luisa Espirito Santo Oliveira, Pedro Marques Garibaldi, MD, Lorena Lobo Figueiredo-Pontes, MD PhD, Belinda Pinto Simões, MD PhD, Leonardo Carvalho Palma, MD PhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5916.
https://doi.org/10.1182/blood-2019-132045
Published: 2019
Journal Articles

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

Thiago Mantello Bianco, MSc, Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Priscila Santos Scheucher, PhD, Isabel Weinhäuser, MSc, Antonio Bruno Alves Silva, BSc, Cleide Lucia Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo M Rego, MD PhD, Fabiola Traina, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2977.
https://doi.org/10.1182/blood-2019-131023
Published: 2019
Journal Articles

Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia

César Alexander Ortiz Rojas, BSc, Diego A Pereira-Martins, MSc, Isabel Weinhäuser, MSc, Luciana Yamamoto Almeida, PhD, Thiago Mantello Bianco, MSc, Lorena Lobo Figueiredo-Pontes, MD PhD, Luisa C A Koury, MD, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, Katia B Pagnano, MD PhD, Ricardo Pasquini, MD, Elenaide C. Nunes, MD, Evandro Maranhão Fagundes, MD, Ana Beatriz F. Gloria, MD, Fabio R. Kerbauy, MD, Armand Keating, MD, Martin S. Tallman, MD, Raul Ribeiro, MD, Richard Dillon, MA, PhD MRCP, FRCPath, Arnold Ganser, MD, Bob Löwenberg, MD PhD, Peter Valk, PhD, Miguel A. Sanz, Nancy Berliner, MD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2719.
https://doi.org/10.1182/blood-2019-131211
Published: 2019
Journal Articles

Metformin Suppress Cellular and Molecular Processes Related to Maintenance and Proliferation of Myeloproliferative Neoplasm Stem Cell

Juan L Coelho-Silva, BSc, MSc, Thiago Mantello Bianco, MSc, Antonio Bruno Alves Silva, BSc, Diego Antonio Pereira-Martins, M.Sc., Natasha Peixoto Fonseca, B.Sc., M.Sc., Isabel Weinhäuser, MSc, Eduardo M Rego, MD PhD, Fernando Chahud, MD PhD, João Agostinho Machado-Neto, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1682.
https://doi.org/10.1182/blood-2019-132115
Published: 2019
Journal Articles

Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Diego Antonio Pereira-Martins, MSc, Patrícia Vianna Bonini Palma, BSc, Josiane Lilian Schiavinato, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4335.
https://doi.org/10.1182/blood-2018-99-115006
Published: 2018
Journal Articles

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Izabela Aparecida Lopes, MSc, Miroslava Kardosova, MSc, Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Cleide Araújo Silva, MSc, Priscila Santos Scheucher, PhD, Daniel G. Tenen, MD, Sanghoon Lee, PhD, Eduardo Magalhães Rego, MD PhD, Robert S. Welner, PhD, Meritxell Alberich-Jorda, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3721.
https://doi.org/10.1182/blood-2018-99-119389
Published: 2018
Journal Articles

NSD1 and NSD2 Transcriptional Levels Might Predict Clinical Outcome in AML Patients

Virginia Mara De Deus Wagatsuma, PhD, Diego Antonio Pereira-Martins, MSc, Mariane Cristina Do Nascimento, BSc, Silvia Elena Sanchez Mendoza, Antonio R. Lucena-Araujo, PhD, Aleide Lima, MSc, Felipe Saldanha-Araujo, PhD, Fabio Pitella, PhD, Fabiola Traina, MD PhD, Maria Isabel A Madeira, MSc, MD, Lorena Lobo Figueiredo-Pontes, MD PhD, Eduardo Magalhães Rego, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5257.
https://doi.org/10.1182/blood-2018-99-119411
Published: 2018
Journal Articles

The Pharmacological IGF1R-IRS1/2 Inhibitor NT157 Presents Multiple Anti-Neoplastic Effects in Myeloproliferative Neoplasms

Bruna Alves Fenerich, BSc, João Agostinho Machado-Neto, BSc, Ana Paula Nunes Rodrigues Alves, MSc, Paula De Melo Campos, MD PhD, Jaqueline Cristina Fernandes, BSc, MSc, Juan Luiz Coelho-Silva, BSc, MSc, Renata Scopim Ribeiro, BSc, MSc, Fernanda B da Silva, BSc and MSc, Priscila Santos Scheucher, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1253.
https://doi.org/10.1182/blood.V130.Suppl_1.1253.1253
Published: 2017
Journal Articles

Imbalance between Tolerant and Cytotoxic Functional Subsets of NK Cells in a JAK2 V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Izabela Aparecida Lopes, MSc, Priscila Santos Scheucher, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MDPhD, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4221.
https://doi.org/10.1182/blood.V130.Suppl_1.4221.4221
Published: 2017
Journal Articles

Metformin Reduces Tumor Burden and Splenomegaly in JAK2 V617F Murine Models

João Agostinho Machado-Neto, BSc, Renata Scopim Ribeiro, BSc, MSc, Juan Luiz Coelho-Silva, BSc, MSc, Christopher A. Eide, Bruna Alves Fenerich, BSc, Jaqueline Cristina Fernandes, BSc, MSc, Ana Paula Nunes Rodrigues Alves, MSc, Priscila S Scheucher, PhD, Cristina E. Tognon, PhD, Lorena Lobo Figueiredo-Pontes, MD PhD, Brian J. Druker, MD, Eduardo Magalhães Rego, MDPhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4222.
https://doi.org/10.1182/blood.V130.Suppl_1.4222.4222
Published: 2017