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Journal Articles

PIM447, a Pan-PIM Kinase Inhibitor, in Combination with Venetoclax Exerts a Potent Anti-Tumor Activity in the Bone Marrow Niche

Fernanda Marconi Roversi, Maura Lima Pereira Bueno, Samara de Sousa Mariano, Fernanda Soares Niemann, Adriana da Silva Santos Duarte, Audrey Bastos, Nádia Ghinelli Amôr, Irene Santos, Jose Andres Yunes, Sandra Pinho, Sara Teresinha Olalla Saad

Blood (2024) 144 (Supplement 1): 3589.

https://doi.org/10.1182/blood-2024-201572

Published: 2024

Journal Articles

Extracellular Vesicles from Sickle Cell Disease Patients with Acute Chest Syndrome Suggest Activation of Endothelial Cells and Coagulation

Cristiane Maria Souza, Irene Pereira dos Santos, Carolina Lanaro, Renata Sesti-Costa, Sara Teresinha Olalla Saad, Bruno D Benites, Fernando Ferreira Costa

Blood (2024) 144 (Supplement 1): 5284.

https://doi.org/10.1182/blood-2024-210018

Published: 2024

Journal Articles

Novel MET Inhibitors Provide a Therapeutic Opportunity for AML By Overcoming the Protective Action of the Bone Marrow Niche

Maura Lima Pereira Bueno, Charles Ayemoba, Anna M Di Staulo, Sen Zhang, Fernanda Soares Niemann, Nádia Ghinelli Amôr, Irene Santos, Adriana da Silva Santos Duarte, Audrey Bastos, Sara Teresinha Olalla Saad, Sandra Pinho, Fernanda Marconi Roversi

Blood (2024) 144 (Supplement 1): 4968.

https://doi.org/10.1182/blood-2024-201077

Published: 2024

Journal Articles

Knockout of the Beta-2 Microglobulin Gene in Adipose Tissue-Derived Cells Using CRISPR/CAS9 System for the Generation of Universal HLA Class I Platelets

Lucas Ferioli Catelli, Marcus Alexandre Finzi Corat, Nádia Ghinelli Amôr, Irene Santos, Fernanda Soares Niemann, Adriana da Silva Santos Duarte, Sara Teresinha Olalla Saad

Blood (2024) 144 (Supplement 1): 1266.

https://doi.org/10.1182/blood-2024-205233

Published: 2024

Journal Articles

Impact and Aggravating Factors of Chronic Pain in Sickle Cell Disease: Results of the Analysis of Promis® Questionnaires and the Metabolomic Profile of Brazilian Adult Patients

Lucas Bibiano Oliveira Souza, Thaís Olalla Bonon Assis, Rogerio Olalla Torres Seber, Adriana da Silva Santos Duarte, Audrey Bastos, Bruno D Benites, Fernando Ferreira Costa, Sara Teresinha Olalla Saad

Blood (2024) 144 (Supplement 1): 3692.

https://doi.org/10.1182/blood-2024-205228

Published: 2024

Journal Articles

Inhibition of MET Tyrosine Kinase Provides a Strategy for Targeting the Inflammatory Tumor Microenvironment

Maura Lima Pereira Bueno, Irene Santos, Nádia Ghinelli Amôr, Adriana Duarte da Silva Santos, Audrey Bastos, Karla Priscila Ferro, Sara Teresinha Olalla Saad, Fernanda Marconi Roversi

Blood (2023) 142 (Supplement 1): 2264.

https://doi.org/10.1182/blood-2023-185204

Published: 2023

Journal Articles

The Proteomic Signature of Extracellular Vesicles from Sickle Cell Anemia Patients Provides Insights into Their Possible Role in the Pathophysiology of the Disease

Cristiane Maria de Souza, Sami Yokoo, Ana Carolina Lima Camargo, Romenia Ramos Domingues, Carolina Lanaro, Marina Dorigatti Borges, Renata Sesti-Costa, Sara Teresinha Olalla Saad, Adriana Franco Paes Leme, Fernando Ferreira Costa

Blood (2023) 142 (Supplement 1): 1120.

https://doi.org/10.1182/blood-2023-189371

Published: 2023

Journal Articles

Effects of Diaphragmatic Breathing in Sickle Cell Disease Patients: Preliminary Data

Fábio Galvão, Marcos Mello Moreira, Mônica Corso Pereira, Sara Teresinha Olalla Saad

Blood (2023) 142 (Supplement 1): 2375.

https://doi.org/10.1182/blood-2023-186756

Published: 2023

Journal Articles

Erythrophagocytosis Mediated By Circulating Monocytes Is Induced By Distinct Mechanisms Depending on the Disease

Marina Dorigatti Borges, Dulcineia Albuquerque, Carolina Lanaro, Sara Teresinha Olalla Saad, Katia B Pagnano, Renata Sesti-Costa, Fernando Ferreira Costa

Blood (2023) 142 (Supplement 1): 2454.

https://doi.org/10.1182/blood-2023-189370

Published: 2023

Journal Articles

HGF Regulation in the Tumor-Supportive Microenvironment Combined with Pan-PIM Kinases Inhibition in Malignant Cells As a Multi-Target Approach for Acute Myeloid Leukemia

Fernanda Marconi Roversi, Maura Lima Pereira Bueno, Fernanda Soares Niemann, Irene Santos, Nádia Ghinelli Amôr, Adriana Duarte da Silva Santos, Audrey Bastos, Sara Teresinha Olalla Saad

Blood (2023) 142 (Supplement 1): 3641.

https://doi.org/10.1182/blood-2023-185179

Published: 2023

Journal Articles

Epigallocatechin-3-Gallate (EGCG) Ameliorates Ineffective Hematopoiesis of Myelodysplasia Syndrome (MDS)

Fernanda Isabel Della Via, Karla Priscila Ferro, Guilherme Rossi Assis-Mendonça, Irene Santos, Nádia Ghinelli Amôr, Fernando Vieira Pericole, Marisa Claudia De Prax, Sara Teresinha Olalla Saad

Blood (2023) 142 (Supplement 1): 6459.

https://doi.org/10.1182/blood-2023-186607

Published: 2023

Journal Articles

A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study of Mitapivat in Patients with Sickle Cell Disease: RISE UP Phase 2 Results

Blood (2023) 142 (Supplement 1): 271.

https://doi.org/10.1182/blood-2023-187033

Published: 2023

Journal Articles

Metabolism-Related Features Identify the Combination Metformin Plus NAMPT Inhibitors As a Selective Treatment Strategy in Acute Myeloid Leukemia

Isabel Weinhaeuser, Diego Pereira-Martins, Dominique Sternadt, Emmanuel F Griessinger, Douglas RA Silveira, Juan L Coelho-Silva, Antonio Bruno Alves-Silva, Ayşegül Erdem, Bruno Koza Lino Duarte, Lynn Quek, Fabiola Traina, Sara Teresinha Olalla Saad, Jacobien R Hilberink, Emanuele Ammatuna, Eduardo Magalhães Rego, Geert A. Huls, Antonio R Lucena-Araujo, Jan Jacob Schuringa

Blood (2023) 142 (Supplement 1): 294.

https://doi.org/10.1182/blood-2023-186061

Published: 2023

Journal Articles

A Landscape of Dendritic Cells Development, Activation and Migration in Mouse Model of Sickle Cell Anemia

Matheus Ajeje Souza, Izabela Felice Paes, Sara Teresinha Olalla Saad, Fernando Ferreira Costa, Renata Sesti-Costa

Blood (2023) 142 (Supplement 1): 3856.

https://doi.org/10.1182/blood-2023-186181

Published: 2023

Journal Articles

Podoplanin Expression Measured By Flow Cytometry Accurately Identifies Patients with Acute Promyelocytic Leukemia at Diagnosis

Camilla Maria de Alencar Saraiva, Carla Roberta Peachazepi Moraes, Bruno Kosa Lino Duarte, Paula de Melo Campos, Gislaine Borba Oliveira, Sara Teresinha Olalla Saad, Erich Vinicius De Paula

Blood (2023) 142 (Supplement 1): 6009.

https://doi.org/10.1182/blood-2023-188321

Published: 2023

Journal Articles

Red Blood Cells Microparticles Are Associated with Hemolysis Markers and Leg Ulceration in Patients with Sickle Cell Disease

Oladele Olatunya, MD, Carolina Lanaro, PhD, Ana Leda Figueiredo Longhini, PhD, Carla Fernanda Franco-Penteado, BSc, PhD, Sara Teresinha Olalla Saad, MD PhD, Kleber Yotsumoto Fertrin, MD PhD, Adekunle Adekile, MBBS, PhD FMCPaed, FWACP, FRCPCH, FRCP, Fernando Ferreira Costa, MD PhD

Blood (2017) 130 (Supplement 1): 3510.

https://doi.org/10.1182/blood.V130.Suppl_1.3510.3510

Published: 2017

Journal Articles

LRP1 Expression in Sickle Cell Disorders: Insights into the Heterogeneity of Monocytic Response to Heme

Leticia Marani, BS, Felipe Vendrame, BS, MSc, Marina Dorigatti Borges, BS, Sara Teresinha Olalla Saad, MD PhD, Fernando Ferreira Costa, MD PhD, Kleber Yotsumoto Fertrin, MD PhD

Blood (2017) 130 (Supplement 1): 3515.

https://doi.org/10.1182/blood.V130.Suppl_1.3515.3515

Published: 2017

Journal Articles

Optimizing the Management of Iron Overload in Patients with Hemoglobin Disorders in Centers with Limited Access to Magnetic Resonance Imaging

Alvaro Henrique Junqueira Tavares, BS, Otavio Rizzi Coelho-Filho, MD PhD, Sara Teresinha Olalla Saad, MD PhD, Fernando Ferreira Costa, MD PhD, Kleber Yotsumoto Fertrin, MD PhD

Blood (2017) 130 (Supplement 1): 5575.

https://doi.org/10.1182/blood.V130.Suppl_1.5575.5575

Published: 2017

Journal Articles

Long Non-Coding Transcript in LEF1 Locus Is a Novel Regulator of Cell Cycle and Apoptotic Pathways in Myeloid Leukemic Cells

Ada Congrains, PhD, Fernanda Niemann, MSc, João Agostinho Machado-Neto, BSc, Sara Teresinha Olalla Saad, MD PhD

Blood (2017) 130 (Supplement 1): 2480.

https://doi.org/10.1182/blood.V130.Suppl_1.2480.2480

Published: 2017

Journal Articles

Screening of Mutations Related to Hereditary Anemias Using NGS-Targeted Sequencing Panel

Maria Carolina Costa Melo Svidnicki, PhD, Fernando Ferreira Costa, MD PhD, Sara Teresinha Olalla Saad, MD PhD

Blood (2017) 130 (Supplement 1): 2209.

https://doi.org/10.1182/blood.V130.Suppl_1.2209.2209

Published: 2017

NARROW

PIM447, a Pan-PIM Kinase Inhibitor, in Combination with Venetoclax Exerts a Potent Anti-Tumor Activity in the Bone Marrow Niche

Extracellular Vesicles from Sickle Cell Disease Patients with Acute Chest Syndrome Suggest Activation of Endothelial Cells and Coagulation

Novel MET Inhibitors Provide a Therapeutic Opportunity for AML By Overcoming the Protective Action of the Bone Marrow Niche

Knockout of the Beta-2 Microglobulin Gene in Adipose Tissue-Derived Cells Using CRISPR/CAS9 System for the Generation of Universal HLA Class I Platelets

Impact and Aggravating Factors of Chronic Pain in Sickle Cell Disease: Results of the Analysis of Promis® Questionnaires and the Metabolomic Profile of Brazilian Adult Patients

Inhibition of MET Tyrosine Kinase Provides a Strategy for Targeting the Inflammatory Tumor Microenvironment

The Proteomic Signature of Extracellular Vesicles from Sickle Cell Anemia Patients Provides Insights into Their Possible Role in the Pathophysiology of the Disease

Effects of Diaphragmatic Breathing in Sickle Cell Disease Patients: Preliminary Data

Erythrophagocytosis Mediated By Circulating Monocytes Is Induced By Distinct Mechanisms Depending on the Disease

HGF Regulation in the Tumor-Supportive Microenvironment Combined with Pan-PIM Kinases Inhibition in Malignant Cells As a Multi-Target Approach for Acute Myeloid Leukemia

Epigallocatechin-3-Gallate (EGCG) Ameliorates Ineffective Hematopoiesis of Myelodysplasia Syndrome (MDS)

A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study of Mitapivat in Patients with Sickle Cell Disease: RISE UP Phase 2 Results

Metabolism-Related Features Identify the Combination Metformin Plus NAMPT Inhibitors As a Selective Treatment Strategy in Acute Myeloid Leukemia

A Landscape of Dendritic Cells Development, Activation and Migration in Mouse Model of Sickle Cell Anemia

Podoplanin Expression Measured By Flow Cytometry Accurately Identifies Patients with Acute Promyelocytic Leukemia at Diagnosis

Red Blood Cells Microparticles Are Associated with Hemolysis Markers and Leg Ulceration in Patients with Sickle Cell Disease

LRP1 Expression in Sickle Cell Disorders: Insights into the Heterogeneity of Monocytic Response to Heme

Optimizing the Management of Iron Overload in Patients with Hemoglobin Disorders in Centers with Limited Access to Magnetic Resonance Imaging

Long Non-Coding Transcript in LEF1 Locus Is a Novel Regulator of Cell Cycle and Apoptotic Pathways in Myeloid Leukemic Cells

Screening of Mutations Related to Hereditary Anemias Using NGS-Targeted Sequencing Panel

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American Society of Hematology

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