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Irene Santos
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Journal Articles

PIM447, a Pan-PIM Kinase Inhibitor, in Combination with Venetoclax Exerts a Potent Anti-Tumor Activity in the Bone Marrow Niche

Fernanda Marconi Roversi, Maura Lima Pereira Bueno, Samara de Sousa Mariano, Fernanda Soares Niemann, Adriana da Silva Santos Duarte, Audrey Bastos, Nádia Ghinelli Amôr, Irene Santos, Jose Andres Yunes, Sandra Pinho, Sara Teresinha Olalla Saad
Journal: Blood
Blood (2024) 144 (Supplement 1): 3589.
https://doi.org/10.1182/blood-2024-201572
Published: 2024
Journal Articles

Novel MET Inhibitors Provide a Therapeutic Opportunity for AML By Overcoming the Protective Action of the Bone Marrow Niche

Maura Lima Pereira Bueno, Charles Ayemoba, Anna M Di Staulo, Sen Zhang, Fernanda Soares Niemann, Nádia Ghinelli Amôr, Irene Santos, Adriana da Silva Santos Duarte, Audrey Bastos, Sara Teresinha Olalla Saad, Sandra Pinho, Fernanda Marconi Roversi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4968.
https://doi.org/10.1182/blood-2024-201077
Published: 2024
Journal Articles

Knockout of the Beta-2 Microglobulin Gene in Adipose Tissue-Derived Cells Using CRISPR/CAS9 System for the Generation of Universal HLA Class I Platelets

Lucas Ferioli Catelli, Marcus Alexandre Finzi Corat, Nádia Ghinelli Amôr, Irene Santos, Fernanda Soares Niemann, Adriana da Silva Santos Duarte, Sara Teresinha Olalla Saad
Journal: Blood
Blood (2024) 144 (Supplement 1): 1266.
https://doi.org/10.1182/blood-2024-205233
Published: 2024
Journal Articles

Inhibition of MET Tyrosine Kinase Provides a Strategy for Targeting the Inflammatory Tumor Microenvironment

Maura Lima Pereira Bueno, Irene Santos, Nádia Ghinelli Amôr, Adriana Duarte da Silva Santos, Audrey Bastos, Karla Priscila Ferro, Sara Teresinha Olalla Saad, Fernanda Marconi Roversi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2264.
https://doi.org/10.1182/blood-2023-185204
Published: 2023
Journal Articles

HGF Regulation in the Tumor-Supportive Microenvironment Combined with Pan-PIM Kinases Inhibition in Malignant Cells As a Multi-Target Approach for Acute Myeloid Leukemia

Fernanda Marconi Roversi, Maura Lima Pereira Bueno, Fernanda Soares Niemann, Irene Santos, Nádia Ghinelli Amôr, Adriana Duarte da Silva Santos, Audrey Bastos, Sara Teresinha Olalla Saad
Journal: Blood
Blood (2023) 142 (Supplement 1): 3641.
https://doi.org/10.1182/blood-2023-185179
Published: 2023
Journal Articles

Epigallocatechin-3-Gallate (EGCG) Ameliorates Ineffective Hematopoiesis of Myelodysplasia Syndrome (MDS)

Fernanda Isabel Della Via, Karla Priscila Ferro, Guilherme Rossi Assis-Mendonça, Irene Santos, Nádia Ghinelli Amôr, Fernando Vieira Pericole, Marisa Claudia De Prax, Sara Teresinha Olalla Saad
Journal: Blood
Blood (2023) 142 (Supplement 1): 6459.
https://doi.org/10.1182/blood-2023-186607
Published: 2023
Journal Articles

NRF2 Is Targeted By the Polyphenol Quercetin and Induces Apoptosis, in Part, through up Regulation of Pro Apoptotic Mirs

Marisa Claudia Alvarez De Prax, PhD, Karla P.V Ferro, PhD, Irene Santos, Cristiane Okuda Torello, PhD, Myriam Salazar-Terreros, PhDMSc, Sara T Olalla Saad, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2529.
https://doi.org/10.1182/blood-2019-130982
Published: 2019