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Journal Articles

Association of Neighbourhood-Level Socioeconomic Deprivation with Mortality Among Patients with Sickle Cell Disease

Suma Vupputuri, Seohyun Kim, Celeena Jefferson, Bogdan Dumitriu, Penelope Howards

Blood (2024) 144 (Supplement 1): 393.

https://doi.org/10.1182/blood-2024-199804

Published: 2024

Journal Articles

A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study of Mitapivat in Patients with Sickle Cell Disease: RISE UP Phase 2 Results

Blood (2023) 142 (Supplement 1): 271.

https://doi.org/10.1182/blood-2023-187033

Published: 2023

Journal Articles

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Xing Fan, MD, Thomas Winkler, MD, Ronan Desmond, MD, Bogdan Dumitriu, MD, Danielle M. Townsley, MD MSc, Maria del Pilar Fernandez Ibanez, Fernanda Gutierrez-Rodrigues, PhD, Sophia Grasmeder, RN, Ma Evette Barranta, Diane Madey, Jennifer Lotter, Janet Valdez, Katherine R. Calvo, MD PhD, Colin Wu, PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 538.

https://doi.org/10.1182/blood-2018-99-112994

Published: 2018

Journal Articles

Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag

Thomas Winkler, MD, Danielle Townsley, MD, Ronan Desmond, MD FRCPath, Bogdan Dumitriu, MD, Sophia Grasmeder, RN, BSN, OCN, Neal S. Young, Cynthia E. Dunbar, MD

Blood (2016) 128 (22): 2682.

https://doi.org/10.1182/blood.V128.22.2682.2682

Published: 2016

Journal Articles

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Kohei Hosokawa, MDPhD, Pawel Muranski, MD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Baoying Liu, PhD, Jared Knickelbein, MD, Keyvan Keyvanfar, BS, Bogdan Dumitriu, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Mariana J. Kaplan, MD, Robert B. Nussenblatt, MD, Austin John Barrett, MDFRCP,FRCPath, John O'Shea, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3613.

https://doi.org/10.1182/blood.V126.23.3613.3613

Published: 2015

Journal Articles

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

Kohei Hosokawa, MDPhD, Sachiko Kajigaya, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Marie Desierto, Olga Rios, Barbara Weinstein, Xingmin Feng, PhD, Neal S. Young, MD

Blood (2015) 126 (23): 3608.

https://doi.org/10.1182/blood.V126.23.3608.3608

Published: 2015

Journal Articles

Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery

Xin Zhao, MD PhD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Thomas Winkler, MD, Ronan Desmond, MD, Matthew J. Olnes, MD PhD, Harshraj Leuva, Bogdan Dumitriu, MD, Cynthia E. Dunbar, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3609.

https://doi.org/10.1182/blood.V126.23.3609.3609

Published: 2015

Journal Articles

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates

Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Phillip Scheinberg, MD, Ronan Desmond, MD, FRCPath, Xingmin Feng, PhD, Olga Rios, RN, Barbara Weinstein, RN, Janet Valdez, PA-C, Thomas Winkler, MD, Marie Desierto, BS, Harshraj Leuva, MBBS, Colin Wu, PhD, Katherine R. Calvo, MD, PhD, Andre Larochelle, MD, PhD, Cynthia E. Dunbar, MD, Neal S. Young, MD

Blood (2015) 126 (23): LBA-2.

https://doi.org/10.1182/blood.V126.23.LBA-2.LBA-2

Published: 2015

Journal Articles

Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders

Arun Balakumaran, Prasun J. Mishra, Edyta Pawelczyk, Sayuri Yoshizawa, Brian J. Sworder, Natasha Cherman, Sergei A. Kuznetsov, Paolo Bianco, Neelam Giri, Sharon A. Savage, Glenn Merlino, Bogdan Dumitriu, Cynthia E. Dunbar, Neal S. Young, Blanche P. Alter, Pamela G. Robey

Blood (2015) 125 (5): 793–802.

https://doi.org/10.1182/blood-2014-06-566810

Published: 2015

Includes: Supplemental data

Journal Articles

Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia

Bogdan Dumitriu, Xingmin Feng, Danielle M. Townsley, Yasutaka Ueda, Tetsuichi Yoshizato, Rodrigo T. Calado, Yanqin Yang, Yoshiyuki Wakabayashi, Sachiko Kajigaya, Seishi Ogawa, Jun Zhu, Neal S. Young

Blood (2015) 125 (4): 706–709.

https://doi.org/10.1182/blood-2014-10-607572

Published: 2015

Includes: Supplemental data

Journal Articles

Telomere Length Recovery Strongly Predicts Overall Survival in Acute Promyelocytic Leukemia

Muhamed Baljevic, MD, Bogdan Dumitriu, MD, Ju-Whei Lee, PhD, Elisabeth Paietta, PhD, Janis Racevskis, Christina Chen, BS, Eytan M. Stein, Robert E Gallagher, MD, Jacob M. Rowe, MD, Frederick R. Appelbaum, MD, Bayard L. Powell, MD, Richard A. Larson, Neal S. Young, MD, Martin S. Tallman, MD

Blood (2014) 124 (21): 2375.

https://doi.org/10.1182/blood.V124.21.2375.2375

Published: 2014

Journal Articles

Acquired Aplastic Anemia: New Genetics, New Genomics

Neal S. Young, MD, Bogdan Dumitriu, MD, Seishi Ogawa, MD PhD

Blood (2014) 124 (21): SCI-21.

https://doi.org/10.1182/blood.V124.21.SCI-21.SCI-21

Published: 2014

Journal Articles

Telomere Length Is Associated with Specific Mutations and Mutation Classes in Patients with Acute Myeloid Leukemia

Justin M. Watts, MD, Bogdan Dumitriu, MD, Patrick Hilden, MS, Christina Chen, BS, Franck Rapaport, PhD, Ashwin Kishtagari, MD, Jihae Ahn, BS, Sean M. Devlin, PhD, Raajit K. Rampal, MD PhD, Ross L. Levine, MD, Neal S. Young, MD, Martin S. Tallman, MD

Blood (2014) 124 (21): 2280.

https://doi.org/10.1182/blood.V124.21.2280.2280

Published: 2014

Journal Articles

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Pawel Muranski, MD, Xingmin Feng, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Christopher S. Hourigan, MD PhD, John Barrett, MD, Neal S. Young, MD

Blood (2014) 124 (21): 2940.

https://doi.org/10.1182/blood.V124.21.2940.2940

Published: 2014

Journal Articles

Chronological Analysis of Clonal Evolution in Acquired Aplastic Anemia

Blood (2014) 124 (21): 253.

https://doi.org/10.1182/blood.V124.21.253.253

Published: 2014

Journal Articles

Telomere Elongation and Hematologic Improvement in Humans Treated with Androgens: A Prospective Clinical Trial of Danazol in Telomeropathies

Bogdan Dumitriu, MD, Danielle M. Townsley, MD, Christina Chen, BS, Rodrigo T. Calado, MD PhD, Phillip Scheinberg, MD, Neal S. Young, MD

Blood (2014) 124 (21): 258.

https://doi.org/10.1182/blood.V124.21.258.258

Published: 2014

Journal Articles

Moderate-dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution

Phillip Scheinberg, Danielle Townsley, Bogdan Dumitriu, Priscila Scheinberg, Barbara Weinstein, Maithili Daphtary, Olga Rios, Colin O. Wu, Neal S. Young

Blood (2014) 124 (18): 2820–2823.

https://doi.org/10.1182/blood-2014-05-573642

Published: 2014

Includes: Supplemental data

Journal Articles

Bone marrow failure and the telomeropathies

Danielle M. Townsley, Bogdan Dumitriu, Neal S. Young

Blood (2014) 124 (18): 2775–2783.

https://doi.org/10.1182/blood-2014-05-526285

Published: 2014

Journal Articles

Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug

Ronan Desmond, Danielle M. Townsley, Bogdan Dumitriu, Matthew J. Olnes, Phillip Scheinberg, Margaret Bevans, Ankur R. Parikh, Kinneret Broder, Katherine R. Calvo, Colin O. Wu, Neal S. Young, Cynthia E. Dunbar

Blood (2014) 123 (12): 1818–1825.

https://doi.org/10.1182/blood-2013-10-534743

Published: 2014

Includes: Supplemental data

Journal Articles

Very Short Telomeres As a Novel Mechanism Of Donor-Cell Derived Leukemia After Cord Blood Transplantation

Bogdan Dumitriu, MD, Yasutaka Ueda, MD, PhD, Sachiko Kajigaya, PhD, Danielle Townsley, MD, Jennifer Cuellar Rodriguez, MD, Dennis D. Hickstein, M.D., Neal S. Young, MD

Blood (2013) 122 (21): 1245.

https://doi.org/10.1182/blood.V122.21.1245.1245

Published: 2013

NARROW

Association of Neighbourhood-Level Socioeconomic Deprivation with Mortality Among Patients with Sickle Cell Disease

A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study of Mitapivat in Patients with Sickle Cell Disease: RISE UP Phase 2 Results

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates

Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders

Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia

Telomere Length Recovery Strongly Predicts Overall Survival in Acute Promyelocytic Leukemia

Acquired Aplastic Anemia: New Genetics, New Genomics

Telomere Length Is Associated with Specific Mutations and Mutation Classes in Patients with Acute Myeloid Leukemia

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

Chronological Analysis of Clonal Evolution in Acquired Aplastic Anemia

Telomere Elongation and Hematologic Improvement in Humans Treated with Androgens: A Prospective Clinical Trial of Danazol in Telomeropathies

Moderate-dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution

Bone marrow failure and the telomeropathies

Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug

Very Short Telomeres As a Novel Mechanism Of Donor-Cell Derived Leukemia After Cord Blood Transplantation

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American Society of Hematology

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American Society of Hematology

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