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Nicolas Papadopoulos
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Journal Articles

Modulation of human thrombopoietin receptor conformations uncouples JAK2 V617F-driven activation from cytokine-induced stimulation

Nicolas Papadopoulos, Ajda Pristavec, Audrey Nédélec, Gabriel Levy, Judith Staerk, Stefan N. Constantinescu
Journal: Blood
Blood (2023) 142 (21): 1818–1830.
https://doi.org/10.1182/blood.2022019580
Published: 2023
Includes: Supplemental data
Journal Articles

GATA1 Target Gene CSF2RB Is Functionally Coupled to MPL and Marks a TPO-Dependent Preleukemic TAM Cell Population Sustained By the Fetal Liver but Not Bone Marrow

David Cruz Hernandez, Nicolas Papadopoulos, Elise Sepulchre, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Leila Varghese, Gabriel Levy, Irene Roberts, Stefan N Constantinescu, Paresh Vyas
Journal: Blood
Blood (2023) 142 (Supplement 1): 404.
https://doi.org/10.1182/blood-2023-174449
Published: 2023
Journal Articles

An Atypical Somatic Calr Variant Acquired in Cis to a Germline Calr variant Induces Constitutive Signaling of the Thrombopoietin Receptor and Results in Essential Thrombocythemia

Laetitia Borderon, Jihyun Song, Soo Jin Kim, Christophe Marzac, Christine Bellanné-Chantelot, Nicolas Papadopoulos, Stefan N. Constantinescu, William Vainchenker, Isabelle Plo, Josef T. Prchal, Caroline Marty
Journal: Blood
Blood (2023) 142 (Supplement 1): 3161.
https://doi.org/10.1182/blood-2023-179381
Published: 2023
Journal Articles

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms

Christian Pecquet, Nicolas Papadopoulos, Thomas Balligand, Ilyas Chachoua, Amandine Tisserand, Gaëlle Vertenoeil, Audrey Nédélec, Didier Vertommen, Anita Roy, Caroline Marty, Harini Nivarthi, Jean-Philippe Defour, Mira El-Khoury, Eva Hug, Andrea Majoros, Erica Xu, Oleh Zagrijtschuk, Tudor E. Fertig, Daciana S. Marta, Heinz Gisslinger, Bettina Gisslinger, Martin Schalling, Ilaria Casetti, Elisa Rumi, Daniela Pietra, Chiara Cavalloni, Luca Arcaini, Mario Cazzola, Norio Komatsu, Yoshihiko Kihara, Yoshitaka Sunami, Yoko Edahiro, Marito Araki, Roman Lesyk, Veronika Buxhofer-Ausch, Sonja Heibl, Florence Pasquier, Violaine Havelange, Isabelle Plo, William Vainchenker, Robert Kralovics, Stefan N. Constantinescu
Journal: Blood
Blood (2023) 141 (8): 917–929.
https://doi.org/10.1182/blood.2022016846
Published: 2023
Includes: Supplemental data
Journal Articles

A Novel Autosomal Dominant JAK2 R715T Mutation Causes Polycythemia Vera in 3 Generations

Soo Jin Kim, Jihyun Song, Nicolas Papadopoulos, Jessica Meznarich, Grace Min, Stefan N. Constantinescu, Josef T. Prchal
Journal: Blood
Blood (2022) 140 (Supplement 1): 6742–6743.
https://doi.org/10.1182/blood-2022-170075
Published: 2022
Journal Articles

Modulation of the Human Thrombopoietin Receptor Conformation Uncouples JAK2 V617F-Driven from Cytokine-Induced Activation

Nicolas Papadopoulos, Ajda Pristavec, Gabriel Levy, Audrey Nédélec, Judith Staerk, Stefan N. Constantinescu
Journal: Blood
Blood (2022) 140 (Supplement 1): 3878–3879.
https://doi.org/10.1182/blood-2022-166405
Published: 2022
Journal Articles

Canonical Thrombopoietin Receptor Mutants in Myeloproliferative Neoplasms Rely Differently on the Extracellular Domain of the Receptor but Share Similar Mechanisms of Inactivation: An Open Field for the Development of New Therapies

Gabriel Levy, Nicolas Papadopoulos, Christian Pecquet, Jean-Philippe Defour, Emilie Leroy, Nabih Maslah, Bruno Cassinat, Steven Smith, Stefan N Constantinescu
Journal: Blood
Blood (2022) 140 (Supplement 1): 8736–8737.
https://doi.org/10.1182/blood-2022-168663
Published: 2022