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Philip J. Lupo
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Journal Articles

Genome-Wide Association Study of Acute Lymphoblastic Leukemia in Hispanic/Latino Children Identifies a Putatively Novel Risk Locus at Chromosome 5q31.1

Tanxin Liu, Jalen Langie, Wenjian Yang, Libby Morimoto, Xiaomei Ma, Catherine Metayer, Philip J Lupo, Michael E. Scheurer, Jun J. Yang, Joseph L. Wiemels, Charleston W.K. Chiang, Adam J. de Smith
Journal: Blood
Blood (2024) 144 (Supplement 1): 317.
https://doi.org/10.1182/blood-2024-208796
Published: 2024
Journal Articles

A Children's Oncology Group Clinical Trial of Long-Term Outcomes in Survivors of Down Syndrome-Associated Acute Leukemia (ALTE22C1): Clinical Trial in Progress

Maria Monica Gramatges, Lauren N Sanclemente, Lacey Hall, Danielle L Mitchell, Olga A Taylor, Tanya Shannon, Tyler Brown, Michelle M Nuño, Smita Bhatia, Eric J. Chow, Kelly D. Getz, Johann K. Hitzler, Amanda M Li, Kaitlin McCloskey, Paul C Nathan, Maureen M. O'Brien, Serina Patel, Anupam Verma, Angela R Yarbrough, Geraldine Aubert, Tracie C Rosser, Lisa M Jacola, Philip J Lupo, Karen R Rabin
Journal: Blood
Blood (2024) 144 (Supplement 1): 2808.1.
https://doi.org/10.1182/blood-2024-203724
Published: 2024
Journal Articles

Evaluation of Methotrexate Pharmacogenomic Variants to Predict Acute Neurotoxicity in Children with Acute Lymphoblastic Leukemia

Austin L Brown, Rachel Harris, Olga A Taylor, Mark Zobeck, Melanie Brooke Bernhardt, Maria Monica Monica Gramatges, Ashley Chavana, Alanna Morrison, Kathleen Ludwig, Laura J. Klesse, Kenneth Matthew Heym, Timothy Griffin, Rodrigo Erana, Juan C. Bernini, Han Chen, Bing Yu, Melissa A. Richard, Philip J Lupo, Karen R Rabin, Michael E. Scheurer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4190.
https://doi.org/10.1182/blood-2024-200891
Published: 2024
Journal Articles

Identification of Germline, Ancestry-Specific Variants for Langerhans Cell Histiocytosis in Hispanic Patients

Priya Bhatia Shetty, Erin Peckham-Gregory, Erik Stricker, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer
Journal: Blood
Blood (2023) 142 (Supplement 1): 4581.
https://doi.org/10.1182/blood-2023-191003
Published: 2023
Journal Articles

Expanded Assessments of Germline Genetic Variants Identify Additional Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya Bhatia Shetty, Erik Stricker, Danielle Mitchell, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer
Journal: Blood
Blood (2023) 142 (Supplement 1): 3193.
https://doi.org/10.1182/blood-2023-189670
Published: 2023
Journal Articles

Association of Latino Ethnicity with Cytogenetic Subtypes in Pediatric Acute Myeloid Leukemia

Kevin Wells Tien, Jennifer M. Geris, Chi-Fan Lin, Charles Cook, Olga Taylor, Maria Isabel Castellanos, Van Thu Huynh, Kathleen Ludwig, Laura J. Klesse, Sandi Pruitt, Amy Hughes, Kenneth Matthew Heym, Timothy Griffin, Rodrigo Erana, Juan C. Bernini, Karen R. Rabin, Michael E. Scheurer, Philip J. Lupo, Maria Monica Gramatges
Journal: Blood
Blood (2023) 142 (Supplement 1): 4313.
https://doi.org/10.1182/blood-2023-186968
Published: 2023
Journal Articles

Development of a Novel Methotrexate-Related Neurotoxicity Risk Score in Pediatric Acute Leukemia: A Report from the Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Consortium

Rachel Harris, Olga Taylor, Melanie Brooke Bernhardt, Ashley Chavana, Mark Zobeck, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L Brown
Journal: Blood
Blood (2023) 142 (Supplement 1): 2828.
https://doi.org/10.1182/blood-2023-189986
Published: 2023
Journal Articles

Distance to Care Predicts Clinical Trial Enrollment on COG ALL Clinical Trials: A Report from the Children's Oncology Group

Lena E Winestone, Sumit Gupta, Jeannette Sample, David Van Riper, Katherine Knowles, Zhiguo (Bruce) Chen, Bo Jiang, Maria C Velez, Mignon L. Loh, Philip J. Lupo, Naomi J Winick, Erin Marcotte
Journal: Blood
Blood (2023) 142 (Supplement 1): 2392.
https://doi.org/10.1182/blood-2023-182477
Published: 2023
Journal Articles

Heritable Variation in Lymphocyte-Related Traits and Risk of Down Syndrome Acute Lymphoblastic Leukemia: A Mendelian Randomization Study

Yunqi Li, Melissa A. Richard, Linda Kachuri, Yao Yu, Ching-Ju Ruu Hsu, Tracie C. Rosser, Elizabeth J. Leslie, Meenakshi Devidas, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Neetha Paul Eduthan, Matthew D. Galbraith, Joaquin Espinosa, Jun J. Yang, Stephanie L. Sherman, Chad D. Huff, Karen R. Rabin, Philip J. Lupo, Adam J. de Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2023-188434
Published: 2023
Journal Articles

Association of Latino Ethnicity with Cytogenetic Subtype in Pediatric Acute Lymphoblastic Leukemia: A Report from the Reducing Ethnic Disparities in Acute Leukemia Consortium

Maria D. Leon-Camarena, Jennifer M. Geris, Maria Isabel Castellanos, Olga Taylor, Veronica Garcia-Morales, Austin L Brown, Pagna Sok, Van Thu Huynh, Kathleen Ludwig, Laura J. Klesse, Sandi Pruitt, Amy Hughes, Kevin Wells Tien, Kenneth Matthew Heym, Timothy Griffin, Rodrigo Erana, Juan C. Bernini, Philip J. Lupo, M. Monica Gramatges, Michael E. Scheurer, Karen R. Rabin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4206.
https://doi.org/10.1182/blood-2023-188022
Published: 2023
Journal Articles

Genomic landscape of Down syndrome–associated acute lymphoblastic leukemia

Zhenhua Li, Ti-Cheng Chang, Jacob J. Junco, Meenakshi Devidas, Yizhen Li, Wenjian Yang, Xin Huang, Dale J. Hedges, Zhongshan Cheng, Mary Shago, Andrew J. Carroll, Nyla A. Heerema, Julie Gastier-Foster, Brent L. Wood, Michael J. Borowitz, Lauren Sanclemente, Elizabeth A. Raetz, Stephen P. Hunger, Eleanor Feingold, Tracie C. Rosser, Stephanie L. Sherman, Mignon L. Loh, Charles G. Mullighan, Jiyang Yu, Gang Wu, Philip J. Lupo, Karen R. Rabin, Jun J. Yang
Journal: Blood
Blood (2023) 142 (2): 172–184.
https://doi.org/10.1182/blood.2023019765
Published: 2023
Includes: Supplemental data
Journal Articles

Epigenetic Age Acceleration and Risk for Chronic Health Conditions in a Diverse Cohort of Survivors of Childhood Acute Lymphoblastic Leukemia

Melissa A Richard, Rachel M Harris, Philip J. Lupo, Austin L Brown, Maria Monica Monica Gramatges
Journal: Blood
Blood (2022) 140 (Supplement 1): 6028–6029.
https://doi.org/10.1182/blood-2022-169730
Published: 2022
Journal Articles

Fine-Mapping of SMAD6 Sequence Data Identifies Additional Putative Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya B Shetty, Howard Lin, Brooks Scull, Erik Ehli, Kenneth L. McClain, Philip J. Lupo, Carl E. Allen, Michael E. Scheurer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3953–3954.
https://doi.org/10.1182/blood-2022-170418
Published: 2022
Journal Articles

Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome

Shaobo Li, Pagna Sok, Keren Xu, Ivo S Muskens, Natalina Elliott, Swe Swe Myint, Priyatama Pandey, Helen M Hansen, Libby M Morimoto, Alice Y Kang, Catherine Metayer, Xiaomei Ma, Beth A Mueller, Anindita Roy, Irene Roberts, Karen R Rabin, Austin L Brown, Philip J. Lupo, Joseph L. Wiemels, Adam J. de Smith
Journal: Blood
Blood (2021) 138 (Supplement 1): 214.
https://doi.org/10.1182/blood-2021-151454
Published: 2021
Journal Articles

Splenic Complications in Sickle Cell Disease: A Retrospective Cohort Review

Alex George, Shannon E. Conneely, Ross Mangum, Philip J. Lupo, Michael E. Scheurer
Journal: Blood
Blood (2021) 138 (Supplement 1): 766.
https://doi.org/10.1182/blood-2021-148027
Published: 2021
Journal Articles

Rates of Laboratory Adverse Events By Chemotherapy Course for Pediatric Acute Leukemia Patients within the Leukemia Electronic Abstraction of Records Network (LEARN)

Tamara P. Miller, MD MSc, Kelly D Getz, Biniyam Demissei, MD PhD, Karen R. Rabin, MD PhD, Marla Daves, MD, Philip J. Lupo, PhD MPH, Michael E. Scheurer, PhD MPH, Evanette Burrows, MPH, Brian T. Fisher, DO, MSCE, Robert W. Grundmeier, MD, Judy Lee, Jennifer J. Wilkes, MDMSCE, Lena E. Winestone, MD, Maria Monica J. Gramatges, MD PhD, Richard Aplenc, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 333.
https://doi.org/10.1182/blood-2019-130656
Published: 2019
Journal Articles

Hispanic Ethnicity Is Associated with Low End of Induction Absolute Lymphocyte Count in Pediatric Acute Lymphoblastic Leukemia

Adriana Saavedra-Simmons, Wanda LeJeune, M.Sc., Geraldine Aubert, PhD, Kellen Gandy, PhD, Lisa R. Hartman, MD, Jill Hartley, MSN, RN, Rodrigo Erana, MD, Juan C. Bernini, MD, Olga Taylor, MPH, Philip J. Lupo, PhD MPH, Michael E. Scheurer, PhD MPH, Karen R. Rabin, MD PhD, Maria Monica Monica Gramatges, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5197.
https://doi.org/10.1182/blood-2019-131222
Published: 2019
Journal Articles

Transient Elevations in Markers of Hepatic Function during Pediatric Acute Lymphoblastic Leukemia Treatment Are Common but Do Not Influence Outcomes: A Study of 805 Patients from the Learn Consortium

Joanna S. Yi, MD, Tiffany Chambers, MPH, Kelly D Getz, Tamara P. Miller, MDMSc, Evanette Burrows, MPH, Marla Daves, MD, Philip J. Lupo, PhD MPH, Michael E. Scheurer, PhD MPH, Richard Aplenc, MD PhD, Karen R. Rabin, MD PhD, Maria Monica J. Gramatges, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3814.
https://doi.org/10.1182/blood-2019-123992
Published: 2019
Journal Articles

Delays in Therapy Do Not Impact Survival in Childhood Acute Lymphoblastic Leukemia: A Report from the Learn Consortium

Ross Mangum, MD, Tiffany M. Chambers, MPH, Andria Stevens, MPH, Robert C. Lynch, MD, Evanette Burrows, MPH, Tamara P. Miller, MDMSc, Kelly D Getz, Richard Aplenc, MD PhD, Philip J. Lupo, PhD MPH, Maria Monica J. Gramatges, MD PhD, Michael E. Scheurer, PhD MPH, Karen R. Rabin, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1304.
https://doi.org/10.1182/blood-2019-130351
Published: 2019
Journal Articles

Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome

Austin L. Brown, Adam J. de Smith, Vincent U. Gant, Wenjian Yang, Michael E. Scheurer, Kyle M. Walsh, Jonathan M. Chernus, Noah A. Kallsen, Shanna A. Peyton, Gareth E. Davies, Erik A. Ehli, Naomi Winick, Nyla A. Heerema, Andrew J. Carroll, Michael J. Borowitz, Brent L. Wood, William L. Carroll, Elizabeth A. Raetz, Eleanor Feingold, Meenakshi Devidas, Lisa F. Barcellos, Helen M. Hansen, Libby Morimoto, Alice Y. Kang, Ivan Smirnov, Jasmine Healy, Caroline Laverdière, Daniel Sinnett, Jeffrey W. Taub, Jillian M. Birch, Pamela Thompson, Logan G. Spector, Maria S. Pombo-de-Oliveira, Andrew T. DeWan, Charles G. Mullighan, Stephen P. Hunger, Ching-Hon Pui, Mignon L. Loh, Michael E. Zwick, Catherine Metayer, Xiaomei Ma, Beth A. Mueller, Stephanie L. Sherman, Joseph L. Wiemels, Mary V. Relling, Jun J. Yang, Philip J. Lupo, Karen R. Rabin
Journal: Blood
Blood (2019) 134 (15): 1227–1237.
https://doi.org/10.1182/blood.2018890764
Published: 2019
Includes: Supplemental data