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Journal Articles

Expanded Assessments of Germline Genetic Variants Identify Additional Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya Bhatia Shetty, Erik Stricker, Danielle Mitchell, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer
Journal: Blood
Blood (2023) 142 (Supplement 1): 3193.
https://doi.org/10.1182/blood-2023-189670
Published: 2023
Journal Articles

Retrospective Analysis of Clofarabine Salvage Therapy in Refractory Multifocal Langerhans Cell Histiocytosis (LCH)

Deevyashali Parekh, Howard Lin, Kenneth L. McClain, Nitya Gulati, Olive S. Eckstein, Nader Kim El-Mallawany, Jennifer Elise Agrusa, Carl E Allen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4574.
https://doi.org/10.1182/blood-2023-184714
Published: 2023
Journal Articles

Identification of Germline, Ancestry-Specific Variants for Langerhans Cell Histiocytosis in Hispanic Patients

Priya Bhatia Shetty, Erin Peckham-Gregory, Erik Stricker, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer
Journal: Blood
Blood (2023) 142 (Supplement 1): 4581.
https://doi.org/10.1182/blood-2023-191003
Published: 2023
Journal Articles

First Blood : Pre-Therapy BRAF V600E+ PBMC Identifies a Novel Clinical Risk Category for Patients with LCH

Howard Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1791.
https://doi.org/10.1182/blood-2023-180415
Published: 2023
Journal Articles

Responses to Combination Chemotherapy with MAPK Pathway Inhibition in Relapsed and Refractory LCH

Vivekanudeep Karri, Nader Kim El-Mallawany, Howard Lin, Harshal A Abhyankar, Jennifer Elise Agrusa, Jessica Velazquez, Olive S. Eckstein, Nitya Gulati, Carl E Allen, Kenneth L. McClain
Journal: Blood
Blood (2023) 142 (Supplement 1): 6349.
https://doi.org/10.1182/blood-2023-190403
Published: 2023
Journal Articles

Fine-Mapping of SMAD6 Sequence Data Identifies Additional Putative Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya B Shetty, Howard Lin, Brooks Scull, Erik Ehli, Kenneth L. McClain, Philip J. Lupo, Carl E. Allen, Michael E. Scheurer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3953–3954.
https://doi.org/10.1182/blood-2022-170418
Published: 2022
Journal Articles

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Jennifer Agrusa, MD, Elmoataz A Abdel Fattah, MBBCh, Howard Lin, BS, Rikhia Chakraborty, PhD, Brooks Scull, MS, Harshal Abhyankar, MS, Nmazuo Wudo Ozuah, MBBS, Olive S. Eckstein, MD, Terzah M Horton, MD PhD, Kala Kamdar, MD, Kenneth L. McClain, MD PhD, Chris Tsz-Kwong Man, PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2773.
https://doi.org/10.1182/blood-2019-125982
Published: 2019
Journal Articles

Evaluating Anti-TNF-Alpha Therapy in Patients with Relapsed and Refractory Langerhans Cell Histiocytosis

Thomas Burke, BS, Alejandra Legarreta, MD, Howard Lin, Brooks Scull, Olive S. Eckstein, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4941.
https://doi.org/10.1182/blood-2018-99-114295
Published: 2018
Journal Articles

BRAF-V600E in Peripheral Mononuclear Cells and Microglia-like Brain Cells Suggest Hematopoietic Origin of Langerhans Cell Histiocytosis-Associated Neurodegeneration

Daniel Zinn, MD, Jennifer Picarsic, Rikhia Chakraborty, PhD BSc, MSc, Howard Lin, Harshal Abhyankar, MS, Brooks Scull, Albert Shih, Karen Phaik Har Lim, Olive S. Eckstein, MD, Tricia L. Peters, MD, Walter Olea, Thomas Burke, Nabil Ahmed, MD, John Hicks, Brandon Tran, Jeremy Jones, Robert Dauser, Michael R. Jeng, MD, Robert A Baiocchi, MD PhD, Deborah E. Schiff, MD, Stanton Goldman, MD, Kenneth Matthew Heym, MD, Harry Wilson, Benjamin Carcamo, Ashish Kumar, MBBS, Carlos Rodriguez-Galindo, MD, Nicholas Whipple, Patrick Campbell, MD PhD, Geoffrey Murdoch, Simon Heales, Marian Malone, Randy Woltjer, Joseph Quinn, Paul Orchard, MD, Michael Kruer, Ronald Jaffe, Markus G Manz, MD, Sergio Lira, Donald Will Parsons, MD PhD, Miriam Merad, MD, Tsz-kwong Man, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2930.
https://doi.org/10.1182/blood.V130.Suppl_1.2930.2930
Published: 2017
Journal Articles

Transcriptional Profiles, Lineage Tracing with BRAF-V600E and HLA-DQB2 Expression Support a Model of Blood CD1c+ Cells As Precursors to LCH Lesion CD207+ Cells

Karen Phaik Har Lim, Paul Milne, PhD BSc, Michael Poidinger, PhD, Kaibo Duan, PhD, Howard Lin, Harshal Abhyankar, MS, Daniel Zinn, MD, Olive S. Eckstein, MD, Rikhia Chakraborty, PhD BSc, MSc, Evan Newell, PhD, Miriam Merad, MD, Kenneth L. McClain, MD PhD, Chris Tsz-Kwong Man, PhD, Florent Ginhoux, PhD, Matthew P. Collin, MD PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4218.
https://doi.org/10.1182/blood.V130.Suppl_1.4218.4218
Published: 2017
Journal Articles

Plasma Inflammatory Protein Profiles Distinguish Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS

Harshal Abhyankar, MS, Carl E. Allen, MD PhD, Howard Lin, Baruch Goldberg, Brooks Scull, Kenneth L. McClain, MD PhD, Jordana Goldman, Trung Nguyen, Michael B. Jordan, MD, Tsz-kwong Man, Olive S. Eckstein, MD, Joseph Lubega, Dalia Bashir, Rikhia Chakraborty, PhD BSc, MSc, Hector Wong, Eyal Muscal, Daniel Zinn, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1011.
https://doi.org/10.1182/blood.V130.Suppl_1.1011.1011
Published: 2017
Journal Articles

Hydroxyurea: a new old therapy for Langerhans cell histiocytosis

Clinical Trials & Observations
Daniel J. Zinn, Amanda B. Grimes, Howard Lin, Olive Eckstein, Carl E. Allen, Kenneth L. McClain
Journal: Blood
Blood (2016) 128 (20): 2462–2465.
https://doi.org/10.1182/blood-2016-06-721993
Published: 2016
Journal Articles

Inflammatory Plasma Proteins Predict Disease Severity and Response to Therapy in Patients with LCH

Daniel Zinn, MD, Howard Lin, Albert Shih, BS, Brooks Scull, MS, Miguel Dario Cantu, Harshal Abhyankar, MS, Rikhia Chakraborty, PhD BSc, MSc, Karen Phaik Har Lim, Tricia L. Peters, MD, Sergio Lira, MD PhD, Chris Tsz-Kwong, PhD, Kenneth McClain, MD PhD, Miriam Merad, MD PhD, Carl Allen, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4072.
https://doi.org/10.1182/blood.V126.23.4072.4072
Published: 2015