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Journal Articles

Responses to Combination Chemotherapy with MAPK Pathway Inhibition in Relapsed and Refractory LCH

Vivekanudeep Karri, Nader Kim El-Mallawany, Howard Lin, Harshal A Abhyankar, Jennifer Elise Agrusa, Jessica Velazquez, Olive S. Eckstein, Nitya Gulati, Carl E Allen, Kenneth L. McClain

Blood (2023) 142 (Supplement 1): 6349.

https://doi.org/10.1182/blood-2023-190403

Published: 2023

Journal Articles

Retrospective Analysis of Clofarabine Salvage Therapy in Refractory Multifocal Langerhans Cell Histiocytosis (LCH)

Deevyashali Parekh, Howard Lin, Kenneth L. McClain, Nitya Gulati, Olive S. Eckstein, Nader Kim El-Mallawany, Jennifer Elise Agrusa, Carl E Allen

Blood (2023) 142 (Supplement 1): 4574.

https://doi.org/10.1182/blood-2023-184714

Published: 2023

Journal Articles

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

Amel Sengal, Jessica Velazquez, Meryl Hahne, Thomas M. Burke, Harshal Abhyankar, Robert Reyes, Walter Olea, Brooks Scull, Olive S. Eckstein, Camille Bigenwald, Catherine M. Bollard, Wendong Yu, Miriam Merad, Kenneth L. McClain, Carl E. Allen, Rikhia Chakraborty

Blood (2021) 137 (13): 1777–1791.

https://doi.org/10.1182/blood.2020005867

Published: 2021

Includes: Supplemental data

Journal Articles

Incorporation of Thiotepa in a Reduced Intensity Conditioning Regimen Leads to Improved Engraftment after Stem Cell Transplant for Patients with Hemophagocytic Lymphohistiocytosis

Swati Naik, MBBS, Olive S. Eckstein, MD, Ghadir Sasa, MD, Robert A. Krance, MD, Carl E. Allen, MD PhD, Helen E. Heslop, MD DSc, Caridad A. Martinez, MD

Blood (2019) 134 (Supplement_1): 3273.

https://doi.org/10.1182/blood-2019-132120

Published: 2019

Journal Articles

Genomic Characterization of a Pediatric Cohort with Non-Malignant Lymphoproliferative Disorders

Blood (2019) 134 (Supplement_1): 83.

https://doi.org/10.1182/blood-2019-131884

Published: 2019

Journal Articles

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Jennifer Agrusa, MD, Elmoataz A Abdel Fattah, MBBCh, Howard Lin, BS, Rikhia Chakraborty, PhD, Brooks Scull, MS, Harshal Abhyankar, MS, Nmazuo Wudo Ozuah, MBBS, Olive S. Eckstein, MD, Terzah M Horton, MD PhD, Kala Kamdar, MD, Kenneth L. McClain, MD PhD, Chris Tsz-Kwong Man, PhD, Carl E. Allen, MD PhD

Blood (2019) 134 (Supplement_1): 2773.

https://doi.org/10.1182/blood-2019-125982

Published: 2019

Journal Articles

Clinical responses and persistent BRAF V600E + blood cells in children with LCH treated with MAPK pathway inhibition

Olive S. Eckstein, Johannes Visser, Carlos Rodriguez-Galindo, Carl E. Allen, the NACHO-LIBRE Study Group

Blood (2019) 133 (15): 1691–1694.

https://doi.org/10.1182/blood-2018-10-878363

Published: 2019

Includes: Supplemental data

Journal Articles

Clinical Outcomes and Molecular Responses in Children with Langerhans Cell Histiocytosis Treated with MAPK Pathway Inhibitors

Olive S. Eckstein, MD, Daniel Zinn, MD, Carolyn Fein Levy, MD, Michael M. Henry, MD, Patrick Campbell, MD, Michael B. Jordan, MD, Ashish R Kumar, MD PhD, Carlos Rodriguez-Galindo, MD PhD, Nobuko Hijiya, MD, Oussama Abla, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD

Blood (2018) 132 (Supplement 1): 3684.

https://doi.org/10.1182/blood-2018-99-120393

Published: 2018

Journal Articles

Evaluating Anti-TNF-Alpha Therapy in Patients with Relapsed and Refractory Langerhans Cell Histiocytosis

Thomas Burke, BS, Alejandra Legarreta, MD, Howard Lin, Brooks Scull, Olive S. Eckstein, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD

Blood (2018) 132 (Supplement 1): 4941.

https://doi.org/10.1182/blood-2018-99-114295

Published: 2018

Journal Articles

Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis

Blood (2018) 132 (1): 89–100.

https://doi.org/10.1182/blood-2017-11-814244

Published: 2018

Includes: Supplemental data

Journal Articles

Plasma Inflammatory Protein Profiles Distinguish Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS

Harshal Abhyankar, MS, Carl E. Allen, MD PhD, Howard Lin, Baruch Goldberg, Brooks Scull, Kenneth L. McClain, MD PhD, Jordana Goldman, Trung Nguyen, Michael B. Jordan, MD, Tsz-kwong Man, Olive S. Eckstein, MD, Joseph Lubega, Dalia Bashir, Rikhia Chakraborty, PhD BSc, MSc, Hector Wong, Eyal Muscal, Daniel Zinn, MD

Blood (2017) 130 (Supplement 1): 1011.

https://doi.org/10.1182/blood.V130.Suppl_1.1011.1011

Published: 2017

Journal Articles

Immune Checkpoint Inhibitors Restore Function of Lesion Infiltrating T Lymphocytes in Langerhans Cell Histiocytosis

Rikhia Chakraborty, PhD BSc, MSc, Carl E. Allen, MD PhD, Amel Sengal, BS, Amos S. Gaikwad, PhD, Harshal Abhyankar, MS, Brooks Scull, Olive S. Eckstein, MD, Miriam Merad, MD, Kenneth L. McClain, MD PhD

Blood (2017) 130 (Supplement 1): 2280.

https://doi.org/10.1182/blood.V130.Suppl_1.2280.2280

Published: 2017

Journal Articles

BRAF-V600E in Peripheral Mononuclear Cells and Microglia-like Brain Cells Suggest Hematopoietic Origin of Langerhans Cell Histiocytosis-Associated Neurodegeneration

Blood (2017) 130 (Supplement 1): 2930.

https://doi.org/10.1182/blood.V130.Suppl_1.2930.2930

Published: 2017

Journal Articles

Transcriptional Profiles, Lineage Tracing with BRAF-V600E and HLA-DQB2 Expression Support a Model of Blood CD1c+ Cells As Precursors to LCH Lesion CD207+ Cells

Karen Phaik Har Lim, Paul Milne, PhD BSc, Michael Poidinger, PhD, Kaibo Duan, PhD, Howard Lin, Harshal Abhyankar, MS, Daniel Zinn, MD, Olive S. Eckstein, MD, Rikhia Chakraborty, PhD BSc, MSc, Evan Newell, PhD, Miriam Merad, MD, Kenneth L. McClain, MD PhD, Chris Tsz-Kwong Man, PhD, Florent Ginhoux, PhD, Matthew P. Collin, MD PhD, Carl E. Allen, MD PhD

Blood (2017) 130 (Supplement 1): 4218.

https://doi.org/10.1182/blood.V130.Suppl_1.4218.4218

Published: 2017

Journal Articles

Efficacy and Toxicity Profile of Clofarabine in Patients with Recurrent/Refractory Langerhans Cell Histiocytosis and Other Histiocytic Disorders

Olive S. Eckstein, MD, Racheal Bingham, CPNP, Erin Christine Peckham, PhD MPH, Austin Brown, MPH, PhD, Carl E. Allen, MD PhD, Kenneth L. McClain, MD PhD

Blood (2016) 128 (22): 1329.

https://doi.org/10.1182/blood.V128.22.1329.1329

Published: 2016

Journal Articles

Hydroxyurea for the Treatment of Relapsed/Refractory Langerhans Cell Histiocytosis

Amanda Bell Grimes, MD, Daniel Zinn, MD, Olive S. Eckstein, MD, Carl Allen, MD PhD, Kenneth McClain, MD PhD

Blood (2015) 126 (23): 1624.

https://doi.org/10.1182/blood.V126.23.1624.1624

Published: 2015

Journal Articles

Mixed Phenotype Acute Leukemia (MPAL) Has a High Frequency of Mutations in Epigenetic Regulatory Genes: Results from Whole Exome Sequencing

Olive S. Eckstein, MD, Linghua Wang, MD PhD, Jyotinder N. Punia, MD, Steven M. Kornblau, MD, Michael Andreef, MD PhD, David A. Wheeler, PhD, Margaret A. Goodell, PhD

Blood (2014) 124 (21): 3560.

https://doi.org/10.1182/blood.V124.21.3560.3560

Published: 2014

NARROW

Responses to Combination Chemotherapy with MAPK Pathway Inhibition in Relapsed and Refractory LCH

Retrospective Analysis of Clofarabine Salvage Therapy in Refractory Multifocal Langerhans Cell Histiocytosis (LCH)

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

Incorporation of Thiotepa in a Reduced Intensity Conditioning Regimen Leads to Improved Engraftment after Stem Cell Transplant for Patients with Hemophagocytic Lymphohistiocytosis

Genomic Characterization of a Pediatric Cohort with Non-Malignant Lymphoproliferative Disorders

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Clinical responses and persistent BRAF V600E + blood cells in children with LCH treated with MAPK pathway inhibition

Clinical Outcomes and Molecular Responses in Children with Langerhans Cell Histiocytosis Treated with MAPK Pathway Inhibitors

Evaluating Anti-TNF-Alpha Therapy in Patients with Relapsed and Refractory Langerhans Cell Histiocytosis

Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis

Plasma Inflammatory Protein Profiles Distinguish Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS

Immune Checkpoint Inhibitors Restore Function of Lesion Infiltrating T Lymphocytes in Langerhans Cell Histiocytosis

BRAF-V600E in Peripheral Mononuclear Cells and Microglia-like Brain Cells Suggest Hematopoietic Origin of Langerhans Cell Histiocytosis-Associated Neurodegeneration

Transcriptional Profiles, Lineage Tracing with BRAF-V600E and HLA-DQB2 Expression Support a Model of Blood CD1c+ Cells As Precursors to LCH Lesion CD207+ Cells

Efficacy and Toxicity Profile of Clofarabine in Patients with Recurrent/Refractory Langerhans Cell Histiocytosis and Other Histiocytic Disorders

Hydroxyurea for the Treatment of Relapsed/Refractory Langerhans Cell Histiocytosis

Mixed Phenotype Acute Leukemia (MPAL) Has a High Frequency of Mutations in Epigenetic Regulatory Genes: Results from Whole Exome Sequencing

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American Society of Hematology

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American Society of Hematology

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