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Amel Sengal
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Journal Articles

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

Amel Sengal, Jessica Velazquez, Meryl Hahne, Thomas M. Burke, Harshal Abhyankar, Robert Reyes, Walter Olea, Brooks Scull, Olive S. Eckstein, Camille Bigenwald, Catherine M. Bollard, Wendong Yu, Miriam Merad, Kenneth L. McClain, Carl E. Allen, Rikhia Chakraborty
Journal: Blood
Blood (2021) 137 (13): 1777–1791.
https://doi.org/10.1182/blood.2020005867
Published: 2021
Includes: Supplemental data
Journal Articles

TCR Repertoire Clonality Analysis and Transcriptome Analyses of Immune Infiltrates in Patients with Langerhans Cell Histiocytosis Can Define Prognostic Biomarkers for Future Therapeutic Development

Rikhia Chakraborty, PhD, Jessica Velasquez, Amel Sengal, BS, Ankita Das, Vasumathi Kode, Nitin Mandloi, Miriam Merad, MD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3601.
https://doi.org/10.1182/blood-2019-129013
Published: 2019
Journal Articles

Blocking MAPK Activation and Immune Checkpoints Reverse Immune Dysfunction and Reduce Disease in a Mouse Model of LCH

Amel Sengal, BS, Meryl Hahne, Jessica Velasquez, Harshal Abhyankar, MS, Thomas Burke, BS, Walter Olea, Robert Reyes, Brooks Scull, MS, Camille Bigenwald, Catherine M. Bollard, MD, Wendong Yu, Miriam Merad, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD, Rikhia Chakraborty, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3602.
https://doi.org/10.1182/blood-2019-128253
Published: 2019
Journal Articles

Creating and Testing a CD207+ Langerhans Cell Histiocytosis-like Cell Line

Jessica Velazquez, BS, Amel Sengal, BS, Carl E. Allen, MD PhD, Rikhia Chakraborty, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5399.
https://doi.org/10.1182/blood-2019-130588
Published: 2019
Journal Articles

Immune Checkpoint Inhibitors Restore Function of Lesion Infiltrating T Lymphocytes in Langerhans Cell Histiocytosis

Rikhia Chakraborty, PhD BSc, MSc, Carl E. Allen, MD PhD, Amel Sengal, BS, Amos S. Gaikwad, PhD, Harshal Abhyankar, MS, Brooks Scull, Olive S. Eckstein, MD, Miriam Merad, MD, Kenneth L. McClain, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2280.
https://doi.org/10.1182/blood.V130.Suppl_1.2280.2280
Published: 2017