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Sandra Cantilena
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Journal Articles

A human genome editing–based MLL :: AF4 ALL model recapitulates key cellular and molecular leukemogenic features

Clara Bueno, Raul Torres-Ruiz, Talia Velasco-Hernandez, Oscar Molina, Paolo Petazzi, Alba Martinez, Virginia Rodriguez, Meritxell Vinyoles, Sandra Cantilena, Owen Williams, Nerea Vega-Garcia, Sandra Rodriguez-Perales, Jose C. Segovia, Oscar Quintana-Bustamante, Anindita Roy, Claus Meyer, Rolf Marschalek, Alastair L. Smith, Thomas A. Milne, Mario F. Fraga, Juan Ramón Tejedor, Pablo Menéndez
Journal: Blood
Blood (2023) 142 (20): 1752–1756.
https://doi.org/10.1182/blood.2023020858
Published: 2023
Includes: Supplemental data
Journal Articles

Interaction with the DNA Binding Domain of MLL and a Small Molecular Drug Induces Proteolysis of MLL-Fusion Proteins and Ablates Leukemic Stem Cell Activity

Jasper de Boer, PhD, Sandra Cantilena, MPhil
Journal: Blood
Blood (2016) 128 (22): 1549.
https://doi.org/10.1182/blood.V128.22.1549.1549
Published: 2016
Journal Articles

Drug Induced MLL Fusion Degradation Via Hsp90 Inhibition

Sandra Cantilena, MPhil, Nicholas Goulden, MD PhD, Owen Williams, PhD, Jasper de Boer, PhD
Journal: Blood
Blood (2015) 126 (23): 4850.
https://doi.org/10.1182/blood.V126.23.4850.4850
Published: 2015