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Talia Velasco-Hernandez
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Journal Articles

NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression

Belén Lopez-Millan, Alba Rubio-Gayarre, Meritxell Vinyoles, Juan L. Trincado, Mario F. Fraga, Narcís Fernandez-Fuentes, Mercedes Guerrero-Murillo, Alba Martinez, Talia Velasco-Hernandez, Aïda Falgàs, Carla Panisello, Gemma Valcarcel, José Luis Sardina, Paula López-Martí, Biola M. Javierre, Beatriz Del Valle-Pérez, Antonio García de Herreros, Franco Locatelli, Rob Pieters, Michela Bardini, Giovanni Cazzaniga, Juan Carlos Rodríguez-Manzaneque, Thomas Hanewald, Rolf Marschalek, Thomas A. Milne, Ronald W. Stam, Juan Ramón Tejedor, Pablo Menendez, Clara Bueno
Journal: Blood
Blood (2024) 144 (19): 2002–2017.
https://doi.org/10.1182/blood.2023022050
Published: 2024
Includes: Supplemental data
Journal Articles

Serially Transplantable, Genetically Modified Patient Derived Xenograft Models of Acute Myeloid Leukemia Represent Primary Patients' Cells and Enable Reliable and Reproducible Preclinical Therapy Trials

Binje Vick, Vindi Jurinovic, Lena Lagally, Kristina Kuhbandner, Lisa Latzko, Chiara Arnreich, Maja Rothenberg-Thurley, Gerulf Hänel, Amelie Muth, Annika Maria Dufour, Stephanie Schneider, Maya C. Andre, Claudia D Baldus, Martin P Carroll, Martin Ebinger, Katharina S. S. Götze, Pablo Menéndez, Jean-Emmanuel Sarry, Talía Velasco-Hernández, Michael von Bergwelt-Baildon, Klaus H Metzeler, Philipp A. Greif, Marion Subklewe, Sebastian Vosberg, Tobias Herold, Karsten Spiekermann, Irmela Jeremias
Journal: Blood
Blood (2024) 144 (Supplement 1): 6085.
https://doi.org/10.1182/blood-2024-198652
Published: 2024
Journal Articles

A human genome editing–based MLL :: AF4 ALL model recapitulates key cellular and molecular leukemogenic features

Clara Bueno, Raul Torres-Ruiz, Talia Velasco-Hernandez, Oscar Molina, Paolo Petazzi, Alba Martinez, Virginia Rodriguez, Meritxell Vinyoles, Sandra Cantilena, Owen Williams, Nerea Vega-Garcia, Sandra Rodriguez-Perales, Jose C. Segovia, Oscar Quintana-Bustamante, Anindita Roy, Claus Meyer, Rolf Marschalek, Alastair L. Smith, Thomas A. Milne, Mario F. Fraga, Juan Ramón Tejedor, Pablo Menéndez
Journal: Blood
Blood (2023) 142 (20): 1752–1756.
https://doi.org/10.1182/blood.2023020858
Published: 2023
Includes: Supplemental data
Journal Articles

Distinct roles for PARP-1 and PARP-2 in c-Myc–driven B-cell lymphoma in mice

Miguel A. Galindo-Campos, Nura Lutfi, Sarah Bonnin, Carlos Martínez, Talia Velasco-Hernandez, Violeta García-Hernández, Juan Martín-Caballero, Coral Ampurdanés, Ramón Gimeno, Lluis Colomo, Gaël Roué, Guillaume Guilbaud, Françoise Dantzer, Pilar Navarro, Matilde Murga, Oscar Fernández-Capetillo, Anna Bigas, Pablo Menéndez, Julian E. Sale, José Yélamos
Journal: Blood
Blood (2022) 139 (2): 228–239.
https://doi.org/10.1182/blood.2021012805
Published: 2022
Includes: Supplemental data
Journal Articles

Design and in Vitro Evaluation of a CAR-T Prototype (ARI-0003) Targeting CD123 for Acute Myeloid Leukemia

Alex Bataller Torralba, Néstor Tirado, Diego Sánchez-Martínez, Talía Velasco-Hernández, Aina Oliver-Caldés, Sandra Castaño-Díez, Francesca Guijarro, Marina Diaz-Beyá, Manel Juan, Pablo Engel, Clara Bueno, Pablo Menendez, Álvaro Urbano-Ispizua, Jordi Esteve
Journal: Blood
Blood (2021) 138 (Supplement 1): 4799.
https://doi.org/10.1182/blood-2021-153356
Published: 2021
Journal Articles

Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia

Clinical Trials & Observations
Diego Sánchez-Martínez, Matteo L. Baroni, Francisco Gutierrez-Agüera, Heleia Roca-Ho, Oscar Blanch-Lombarte, Sara González-García, Montserrat Torrebadell, Jordi Junca, Manuel Ramírez-Orellana, Talía Velasco-Hernández, Clara Bueno, José Luís Fuster, Julia G. Prado, Julien Calvo, Benjamin Uzan, Jan Cools, Mireia Camos, Françoise Pflumio, María Luisa Toribio, Pablo Menéndez
Journal: Blood
Blood (2019) 133 (21): 2291–2304.
https://doi.org/10.1182/blood-2018-10-882944
Published: 2019
Includes: Supplemental data
Journal Articles

HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia

Talia Velasco-Hernandez, Axel Hyrenius-Wittsten, Matilda Rehn, David Bryder, Jörg Cammenga
Journal: Blood
Blood (2014) 124 (24): 3597–3607.
https://doi.org/10.1182/blood-2014-04-567065
Published: 2014
Includes: Supplemental data