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Journal Articles

Impact of Minimal Residual Disease Analysis in the Era of Rituximab Maintenance in Follicular Lymphoma: Data from “FOLL12” Phase III Trial of the Fondazione Italiana Linfomi

Simone Ferrero, Ilaria Del Giudice, Sara Galimberti, Valter Gattei, Luigi Marcheselli, Elisa Genuardi, Daniela Drandi, Mariapia Pironti, Irene Dogliotti, Aurora Maria Civita, Irene Della Starza, Giovanni Manfredi Assanto, Francesca Guerrini, Clara Bono, Riccardo Bomben, Carola Boccomini, Lucia Farina, Jacopo Olivieri, Luca Arcaini, Federica Cavallo, Filippo Ballerini, Gloria Margiotta Casaluci, Vittorio Ruggero Zilioli, Manuela Zanni, Gerardo Musuraca, Anna Merli, Benedetta Bianchi, Silvia Bolis, Vincenzo Pavone, Annalisa Chiarenza, Annalisa Arcari, Catello Califano, Samantha Pozzi, Massimo Massaia, Annarita Conconi, Tommasina Perrone, Donato Mannina, Alessandro Re, Maria Elena Nizzoli, Dimitri Dardanis, Stefano Luminari, Marco Ladetto
Journal: Blood
Blood (2024) 144 (Supplement 1): 339.
https://doi.org/10.1182/blood-2024-194832
Published: 2024
Journal Articles

Minimal Residual Disease Evaluation in the Context of V-Rbac, a Risk-Tailored Phase II Trial of the Fondazione Italiana Linfomi (FIL)

Riccardo Bomben, Daniela Drandi, Irene Della Starza, Clara Bono, Andrea Evangelista, Omar Perbellini, Tamara Bittolo, Elisa Genuardi, Massimo Degan, Simone Ragaini, Maria Chiara Tisi, Anna Merli, Francesca Quaglia, Alessandro Re, Claudia Castellino, Vittorio Ruggero Zilioli, Francesco Piazza, Paolo Corradini, Stefan Hohaus, Gerardo Musuraca, Francesca Gaia Rossi, Benedetta Puccini, Federica Cavallo, Filippo Ballerini, Luca Arcaini, Valter Gattei, Ilaria Del Giudice, Sara Galimberti, Carlo Visco, Simone Ferrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 4362.
https://doi.org/10.1182/blood-2024-203004
Published: 2024
Journal Articles

Exploring the Cell-Free Transcriptome As Biomarker Source in IgM Gammopathies: New Insights from the Fondazione Italiana Linfomi “BIO-WM” Trial

Philippe Decruyenaere, Daniela Drandi, Kimberly Verniers, Simone Ragaini, Jasper Anckaert, Veronica Peri, Elisa Genuardi, Federica Cavallo, Luigi Marcheselli, Irene Dogliotti, Emanuele Cencini, Dario Marino, Angela Ferrari, Simona Tomassetti, Luca Laurenti, Giacomo Loseto, Monia Marchetti, Annelien Morlion, Ramon García-Sanz, Fritz Offner, Benedetto Bruno, Marzia Varettoni, Jo Vandesompele, Simone Ferrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 3297.
https://doi.org/10.1182/blood-2024-198382
Published: 2024
Journal Articles

MRD Monitoring By Euroclonality IGH Based NGS Approach Predicts Outcome in Follicular Lymphoma Patients Lacking a Conventional BCL2::IGH Marker: A Substudy from the Fondazione Italiana Linfomi (FIL) FOLL12 Trial

Elisa Genuardi, Beatrice Alessandria, Irene Della Starza, Francesca Guerrini, Riccardo Bomben, Daniela Drandi, Martina Ferrante, Clara Bono, Roberta Soscia, Tamara Bittolo, Simone Ragaini, Salvatrice Mancuso, Emanuele Cencini, Nicola Di Renzo, Clara Mannarella, Marco Murineddu, Vittorio Stefoni, Riccardo Centurioni, Luca Baldini, Aurora Maria Civita, Valter Gattei, Sara Galimberti, Ilaria Del Giudice, Benedetto Bruno, Massimo Federico, Marco Ladetto, Christiane Pott, Stefano Luminari, Simone Ferrero
Journal: Blood
Blood (2023) 142 (Supplement 1): 4373.
https://doi.org/10.1182/blood-2023-181813
Published: 2023
Journal Articles

Looking for a needle in the haystack of CLL

Simone Ferrero, Elisa Genuardi
Journal: Blood
Blood (2023) 141 (5): 445–447.
https://doi.org/10.1182/blood.2022018077
Published: 2023
Journal Articles

Genotyping and Minimal Residual Disease (MRD) Assessment in cfDNA By the Euroclonality-NGS DNA Capture (EC-NDC) Panel in Mantle Cell Lymphoma (MCL)

Mouhamad Khouja, Elisa Genuardi, Simone Ferrero, Beatrice Alessandria, Onno Verhagen, Christa Homburg, Vincent H.J. van der Velden, Paula Gameiro, Ramón García-Sanz, Alejandro Medina, Eva Fronkova, Monika Brüggemann, Martin Dreyling, Eva Hoster, Anton Langerak, Nikos Darzentas, Karol Pal, Peter James Stewart, David Gonzalez, Christiane Pott
Journal: Blood
Blood (2022) 140 (Supplement 1): 3518–3520.
https://doi.org/10.1182/blood-2022-166043
Published: 2022
Journal Articles

Dissecting MRD Kinetics By Automated Computational Analysis to Improve Outcome Prediction in Mantle Cell Lymphoma: A Bioinformatic Substudy from the Fondazione Italiana Linfomi (FIL) MCL0208 Clinical Trial

Francesca Cordero, Simone Ferrero, Simone Pernice, Elisa Genuardi, Roberta Sirovich, Beatrice Alessandria, Andrea Evangelista, Simone Ragaini, Maurizio Martelli, Alice Di Rocco, Alessandro Re, Chiara Pagani, Vittorio Stefoni, Federica Cavallo, Carola Boccomini, Monica Balzarotti, Vittorio Ruggero Zilioli, Maria Gomes da Silva, Luca Arcaini, Melania Celli, Gian Maria Zaccaria, Dora Tortarolo, Sergio Cortelazzo, Marco Ladetto
Journal: Blood
Blood (2022) 140 (Supplement 1): 9375–9377.
https://doi.org/10.1182/blood-2022-159949
Published: 2022
Journal Articles

Punctual and kinetic MRD analysis from the Fondazione Italiana Linfomi MCL0208 phase 3 trial in mantle cell lymphoma

Clinical Trials & Observations
Simone Ferrero, Daniele Grimaldi, Elisa Genuardi, Daniela Drandi, Gian Maria Zaccaria, Beatrice Alessandria, Marco Ghislieri, Martina Ferrante, Andrea Evangelista, Barbara Mantoan, Gabriele De Luca, Piero Maria Stefani, Fabio Benedetti, Ivana Casaroli, Manuela Zanni, Claudia Castellino, Vincenzo Pavone, Mario Petrini, Francesca Re, Stefan Hohaus, Gerardo Musuraca, Nicola Cascavilla, Chiara Ghiggi, Anna Marina Liberati, Sergio Cortelazzo, Marco Ladetto
Journal: Blood
Blood (2022) 140 (12): 1378–1389.
https://doi.org/10.1182/blood.2021014270
Published: 2022
Includes: Supplemental data
Journal Articles

A Comprehensive and Systematic Analysis of Minimal Residual Disease (MRD) Monitoring in Follicular Lymphoma: Results from the Fondazione Italiana Linfomi (FIL) FOLL12 Trial

Marco Ladetto, Simone Ferrero, Ilaria Del Giudice, Sara Galimberti, Valter Gattei, Luigi Marcheselli, Barbara Mantoan, Elisa Genuardi, Beatrice Alessandria, Martina Ferrante, Irene Dogliotti, Irene Della Starza, Lucia Anna De Novi, Marzia Cavalli, Susanna Grassi, Elena Ciabatti, Francesca Guerrini, Riccardo Bomben, Massimo Degan, Eva Zaina, Tommasina Perrone, Mario Petrini, Francesca Re, Attilio Olivieri, Sara Veronica Usai, Donato Mannina, Brunangelo Falini, Delia Rota Scalabrini, Pietro Maria Stefani, Filippo Ballerini, Massimo Federico, Stefano Luminari
Journal: Blood
Blood (2021) 138 (Supplement 1): 41.
https://doi.org/10.1182/blood-2021-146773
Published: 2021
Journal Articles

Pharmacogenomics Drives Lenalidomide Efficacy and MRD Kinetics in Mantle Cell Lymphoma after Autologous Transplantation: Results from the MCL0208 Multicenter, Phase III, Randomized Clinical Trial from the Fondazione Italiana Linfomi (FIL)

Simone Ferrero, MD, Daniele Grimaldi, MD, Elena Arrigoni, Gian Maria Zaccaria, PhD, Beatrice Alessandria, Elisa Genuardi, Gabriele De Luca, Marco Ghislieri, Alice Di Rocco, Alessandro Re, MD, Vittorio Stefoni, MD PhD, Federica Cavallo, Carola Boccomini, MD, Monica Balzarotti, Vittorio Ruggero Zilioli, MD, Gomes da Silva Maria, MD PhD, Luca Arcaini, Anna Lia Molinari, MD, Filippo Ballerini, MD, Andres JM Ferreri, MD, Benedetta Puccini, Giuseppe A. Palumbo, MD PhD, Sara Galimberti, MD PhD, Sergio Cortelazzo, MD, Antonello Di Paolo, Marco Ladetto, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-134875
Published: 2020
Journal Articles

Impact of Minimal Residual Disease (MRD) By Multiparameter Flow Cytometry (MFC) and Next-Generation Sequencing (NGS) on Outcome: Results of Newly Diagnosed Transplant-Eligible Multiple Myeloma (MM) Patients Enrolled in the Forte Trial

Stefania Oliva, Elisa Genuardi, Maria Teresa Petrucci, Mattia D'Agostino, MD, Daniel Auclair, Antonio Spadano, Allison P. Jacob, Michele Cea, Luca De Rosa, Alessandro Gozzetti, Marina Ruggeri, Andrea Capra, Milena Gilestro, Norbert Pescosta, Angelo D. Palmas, Agostina Siniscalchi, Ilan R. Kirsch, Paolo Corradini, Pellegrino Musto, Mario Boccadoro, Elena Zamagni, Francesca Gay, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-137351
Published: 2020
Journal Articles

Euroclonality-NGS DNA Capture Panel for Integrated Analysis of IG/TR Rearrangements, Translocations, Copy Number and Sequence Variation in Lymphoproliferative Disorders

Peter Stewart, PhD, Jana Gazdova, MSc, Nikos Darzentas, PhD, Dorte Wren, PhDFRCPath, Paula Proszek, Grazia Fazio, Simona Songia, Miguel Alcoceba, Maria Eugenia Sarasquete, PhD, Patrick Villarese, PhD, Michèle Y van der Klift, Kim Heezen, Neil McCafferty, MSc, Karol Pal, MSc, Mark Catherwood, PhD, Chang Sik Kim, PhD, Shambhavi Srivastava, PhD, Elizabeth Hodges, PhD, Kostas Stamatopoulos, Wolfram Klapper, Simone Ferrero, MD, Michiel van den Brand, MD, Giovanni Cazzaniga, PhD, Frederic Davi, MD PhD, Ramon Garcia-Sanz, MD PhD, Patricia Groenen, Elizabeth Macintyre, PhDMD, Monika Brüggemann, Christiane Pott, MD PhD, Elisa Genuardi, Anton W Langerak, PhD, David Gonzalez, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 888.
https://doi.org/10.1182/blood-2019-127822
Published: 2019
Journal Articles

Minimal Residual Disease Evaluation By Multiparameter Flow Cytometry and Next Generation Sequencing in the Forte Trial for Newly Diagnosed Multiple Myeloma Patients

Stefania Oliva, Elisa Genuardi, Angelo Belotti, Pio Manlio Mirko Frascione, Monica Galli, Andrea Capra, Massimo Offidani, Federico Vozella, Renato Zambello, Daniel Auclair, Agostina Siniscalchi, Jennifer Yesil, Ombretta Annibali, Ilan M. Kirsch, Simona Caltagirone, Allison P. Jacob, Stelvio Ballanti, Angelo D. Palmas, Antonio Ledda, Paolo Corradini, Paola Omedé, Michele Cavo, Pellegrino Musto, Mario Boccadoro, Francesca Gay, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4322.
https://doi.org/10.1182/blood-2019-124645
Published: 2019
Journal Articles

Comprehensive Minimal Residual Disease (MRD) Analysis of the Fondazione Italiana Linfomi (FIL) MCL0208 Clinical Trial for Younger Patients with Mantle Cell Lymphoma: A Kinetic Model Ensures a More Refined Risk Stratification

Simone Ferrero, MD, Barbero Daniela, Mariella Lo Schirico, Andrea Evangelista, PhD, Annalisa Cifaratti, Daniela Drandi, PhD, Elisa Genuardi, PhD, Daniele Grimaldi, Luigia Monitillo, Gian Maria Zaccaria, PhD, Pietro Maria Stefani, Fabio Benedetti, Ivana Casaroli, Manuela Zanni, MD, Claudia Castellino, Vincenzo Pavone, Mario Petrini, PhD MD Prof, Francesca Re, MDPhD, Stefan Hohaus, Gerardo Musuraca, MD, Nicola Cascavilla, MD, Angela Giovanna Congiu, Anna Marina Liberati, MD, Giovannino Ciccone, MD, Umberto Vitolo, Sergio Cortelazzo, MD, Marco Ladetto, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 920.
https://doi.org/10.1182/blood-2018-99-114442
Published: 2018
Journal Articles

The Engineered MIPI (e-MIPI), a Candidate Data-Mining Based Mantle Cell Lymphoma Prognostic Index Developed from the Dataset of the Fondazione Italiana Linfomi (FIL) MCL0208 Phase III Trial

Gian Maria Zaccaria, PhD, Simone Ferrero, MD, Roberto Passera, PhD, Andrea Evangelista, PhD, Mariella Loschirico, MD, Irene Dogliotti, MD, Marco Ghislieri, Elisa Genuardi, PhD, Riccardo Bomben, PhD, Valter Gattei, MD, Giovannino Ciccone, Monica Tani, MD, Gianluca Gaidano, MD PhD, Stefano Volpetti, MD, Maria Giuseppina Cabras, MD, Nicola Di Renzo, MD, Francesco Merli, MD, Daniele Vallisa, MD, Michele Spina, MD, Anna Pascarella, MD, Giancarlo Latte, MD, Caterina Patti, Gabriele Pozzato, MD, Alberto Fabbri, MD, Sergio Cortelazzo, MD, Marco Ladetto
Journal: Blood
Blood (2018) 132 (Supplement 1): 2890.
https://doi.org/10.1182/blood-2018-99-114168
Published: 2018
Journal Articles

Delphi, a Data Warehouse to Discover Associations between Variables in Clinical Trials: Application to the Fondazione Italiana Linfomi (FIL) MCL0208 Phase III Trial

Gian Maria Zaccaria, MSc, Simone Ferrero, Andrea Evangelista, Samanta Rosati, Cristina Castagneri, Marco Ghislieri, Barbero Daniela, Elisa Genuardi, Mariella Lo Schirico, Alberto Zamò, Umberto Vitolo, Riccardo Bomben, Valter Gattei, MD, Sara Galimberti, PhD MD, Antonello Di Paolo, Davide Rossi, MD PhD, Gianluca Gaidano, MD PhD, Alice Di Rocco, Sergio Cortelazzo, Mario Boccadoro, Gabriella Balestra, Marco Ladetto
Journal: Blood
Blood (2017) 130 (Supplement 1): 3451.
https://doi.org/10.1182/blood.V130.Suppl_1.3451.3451
Published: 2017
Journal Articles

Targeted Locus Amplification (TLA): A Novel Next Generation Sequencing (NGS) Technology to Detect New Molecular Markers and Monitoring Minimal Residual Disease (MRD) in Mantle Cell and Follicular Lymphoma

Elisa Genuardi, Petra Klous, Daniela Drandi, Barbara Mantoan, Luigia Monitillo, Barbero Daniela, Mehmet Yilmaz, Fabio Cattellino, Marika Vasta, Federica Furia, Gian Maria Zaccaria, MSc, Federica Cavallo, Sergio Cortelazzo, Umberto Vitolo, MD, Stefano Luminari, Massimo Federico, Mario Boccadoro, Erik Splinter, Marco Ladetto, Simone Ferrero
Journal: Blood
Blood (2017) 130 (Supplement 1): 2742.
https://doi.org/10.1182/blood.V130.Suppl_1.2742.2742
Published: 2017
Journal Articles

Standardized IGH-Based Next-Generation Sequencing for MRD Detection in Follicular Lymphoma

Christiane Pott, MD, PhD, Henrik Knecht, PhD, Arved Herzog, Elisa Genuardi, Michael Unterhalt, MD PhD, Barbara Mantoan, Irene Dogliotti, Wolfgang Hiddemann, MD PhD, Mario Boccadoro, Dietrich Herrmann, Michael Kneba, MD, Anton W Langerak, Nikos Darzentas, Patricia Groenen, Monika Brüggemann, MD, Eva Hoster, Marco Ladetto, Simone Ferrero
Journal: Blood
Blood (2017) 130 (Supplement 1): 1491.
https://doi.org/10.1182/blood.V130.Suppl_1.1491.1491
Published: 2017
Journal Articles

Distinct Immunogenetic Signatures in IgA Versus IgG Multiple Myeloma

Katerina Gemenetzi, Andreas Agathangelidis, Apostolia Papalexandri, Alejandro Medina, Elisa Genuardi, Theodoros Moysiadis, Evdoxia Hatjiharissi, Maria Papaioannou, Evangelos Terpos, Cristina Jimenez, Chrysavgi Lalayanni, Achilles Anagnostopoulos, Simone Ferrero, Marco Ladetto, MD, Ramon Garcia Sanz, Chrysoula Belessi, Anastasia Hadzidimitriou, Kostas Stamatopoulos, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2062.
https://doi.org/10.1182/blood.V128.22.2062.2062
Published: 2016
Journal Articles

Highly Sensitive Droplet Digital PCR for MYD88 L265P Mutation Detection and Minimal Residual Disease Monitoring in Waldenström Macroglobulinemia

Daniela Drandi, Elisa Genuardi, Paola Ghione, Daniele Grimaldi, Barbara Mantoan, Marina Ruggeri, Daniela Barbero, Luigia Monitillo, Marika Vasta, Eleonora Marzanati, Giulia Verardo, Paola Omedè, Federica Cavallo, Mario Boccadoro, MD, Marco Ladetto, Simone Ferrero
Journal: Blood
Blood (2015) 126 (23): 2645.
https://doi.org/10.1182/blood.V126.23.2645.2645
Published: 2015