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Sergio Cortelazzo
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Journal Articles

Dissecting MRD Kinetics By Automated Computational Analysis to Improve Outcome Prediction in Mantle Cell Lymphoma: A Bioinformatic Substudy from the Fondazione Italiana Linfomi (FIL) MCL0208 Clinical Trial

Francesca Cordero, Simone Ferrero, Simone Pernice, Elisa Genuardi, Roberta Sirovich, Beatrice Alessandria, Andrea Evangelista, Simone Ragaini, Maurizio Martelli, Alice Di Rocco, Alessandro Re, Chiara Pagani, Vittorio Stefoni, Federica Cavallo, Carola Boccomini, Monica Balzarotti, Vittorio Ruggero Zilioli, Maria Gomes da Silva, Luca Arcaini, Melania Celli, Gian Maria Zaccaria, Dora Tortarolo, Sergio Cortelazzo, Marco Ladetto
Journal: Blood
Blood (2022) 140 (Supplement 1): 9375–9377.
https://doi.org/10.1182/blood-2022-159949
Published: 2022
Journal Articles

Punctual and kinetic MRD analysis from the Fondazione Italiana Linfomi MCL0208 phase 3 trial in mantle cell lymphoma

Clinical Trials & Observations
Simone Ferrero, Daniele Grimaldi, Elisa Genuardi, Daniela Drandi, Gian Maria Zaccaria, Beatrice Alessandria, Marco Ghislieri, Martina Ferrante, Andrea Evangelista, Barbara Mantoan, Gabriele De Luca, Piero Maria Stefani, Fabio Benedetti, Ivana Casaroli, Manuela Zanni, Claudia Castellino, Vincenzo Pavone, Mario Petrini, Francesca Re, Stefan Hohaus, Gerardo Musuraca, Nicola Cascavilla, Chiara Ghiggi, Anna Marina Liberati, Sergio Cortelazzo, Marco Ladetto
Journal: Blood
Blood (2022) 140 (12): 1378–1389.
https://doi.org/10.1182/blood.2021014270
Published: 2022
Includes: Supplemental data
Journal Articles

Pharmacogenomics Drives Lenalidomide Efficacy and MRD Kinetics in Mantle Cell Lymphoma after Autologous Transplantation: Results from the MCL0208 Multicenter, Phase III, Randomized Clinical Trial from the Fondazione Italiana Linfomi (FIL)

Simone Ferrero, MD, Daniele Grimaldi, MD, Elena Arrigoni, Gian Maria Zaccaria, PhD, Beatrice Alessandria, Elisa Genuardi, Gabriele De Luca, Marco Ghislieri, Alice Di Rocco, Alessandro Re, MD, Vittorio Stefoni, MD PhD, Federica Cavallo, Carola Boccomini, MD, Monica Balzarotti, Vittorio Ruggero Zilioli, MD, Gomes da Silva Maria, MD PhD, Luca Arcaini, Anna Lia Molinari, MD, Filippo Ballerini, MD, Andres JM Ferreri, MD, Benedetta Puccini, Giuseppe A. Palumbo, MD PhD, Sara Galimberti, MD PhD, Sergio Cortelazzo, MD, Antonello Di Paolo, Marco Ladetto, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-134875
Published: 2020
Journal Articles

Identification of a Chromatin-Splicing Mutational Signature to Define Secondary Acute Myeloid Leukemia: A Report from the Northern Italy Leukemia Group (NILG) Prospective Trial 02/06

Chiara Caprioli, MD, Federico Lussana, MD, Silvia Salmoiraghi, BioSc, Roberta Cavagna, BioSc, Ksenija Buklijas, BioSc, Lara Elidi, BioSc, Pamela Zanghì, BioSc, Anna Michelato, PhD, Federica Delaini, MSc, Elena Oldani, MSc, Dario Ferrero, MD, Ernesta Audisio, MD, Filippo Marmont, MD, Elisabetta Terruzzi, MD, Lorella De Paoli, MD, Chiara Cattaneo, MD, Erika Borlenghi, MD, Irene Cavattoni, MD, Monica Tajana, MD, Anna Maria Scattolin, MD, Daniele Giovanni Mattei, MD, Paolo Corradini, Leonardo Campiotti, MD, Fabio Ciceri, MD, Massimo Bernardi, MD, Elisabetta Todisco, MD PhD, Agostino Cortelezzi, MD, Sergio Cortelazzo, MD, Giacomo Gianfaldoni, MD, Alberto Bosi, MD, Brunangelo Falini, MD PhD, Tamara Intermesoli, MD, Chiara Pavoni, Statistician, Renato Bassan, MD, Orietta Spinelli, PhD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1443.
https://doi.org/10.1182/blood-2019-124497
Published: 2019
Journal Articles

Clinical Impact of an Accurate Genetic Characterization of Older Acute Myeloid Leukemia Patients: A Report from the Northern Italy Leukemia Group (NILG) Randomized Trial 02/06

Chiara Caprioli, MD, Tamara Intermesoli, MD, Orietta Spinelli, PhD, Silvia Salmoiraghi, MSc, Pamela Zanghì, MSc, Roberta Cavagna, MSc, Anna Michelato, PhD, Ksenija Buklijas, MSc, Federica Delaini, MSc, Elena Oldani, MSc, Giacomo Gianfaldoni, MD, Dario Ferrero, MD, Elisabetta Terruzzi, MD, Lorella De Paoli, MD, Chiara Cattaneo, MD, Erika Borlenghi, MD, Irene Cavattoni, MD, Monica Tajana, MD, Anna Maria Scattolin, MD, Daniele Giovanni Mattei, MD, Paolo Corradini, MD, Leonardo Campiotti, MD, Fabio Ciceri, MD, Massimo Bernardi, MD, Elisabetta Todisco, MD, Agostino Cortelezzi, MD, Sergio Cortelazzo, MD, Ernesta Audisio, MD, Filippo Marmont, MD, Alberto Bosi, MD, Brunangelo Falini, MD PhD, Chiara Pavoni, Statistician, Renato Bassan, MD, Alessandro Rambaldi, MD, Federico Lussana, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 434.
https://doi.org/10.1182/blood-2018-99-113869
Published: 2018
Journal Articles

Comprehensive Minimal Residual Disease (MRD) Analysis of the Fondazione Italiana Linfomi (FIL) MCL0208 Clinical Trial for Younger Patients with Mantle Cell Lymphoma: A Kinetic Model Ensures a More Refined Risk Stratification

Simone Ferrero, MD, Barbero Daniela, Mariella Lo Schirico, Andrea Evangelista, PhD, Annalisa Cifaratti, Daniela Drandi, PhD, Elisa Genuardi, PhD, Daniele Grimaldi, Luigia Monitillo, Gian Maria Zaccaria, PhD, Pietro Maria Stefani, Fabio Benedetti, Ivana Casaroli, Manuela Zanni, MD, Claudia Castellino, Vincenzo Pavone, Mario Petrini, PhD MD Prof, Francesca Re, MDPhD, Stefan Hohaus, Gerardo Musuraca, MD, Nicola Cascavilla, MD, Angela Giovanna Congiu, Anna Marina Liberati, MD, Giovannino Ciccone, MD, Umberto Vitolo, Sergio Cortelazzo, MD, Marco Ladetto, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 920.
https://doi.org/10.1182/blood-2018-99-114442
Published: 2018
Journal Articles

Lenalidomide Maintenance after Autologous Transplantation Prolongs PFS in Young MCL Patients: Results of the Randomized Phase III MCL 0208 Trial from Fondazione Italiana Linfomi (FIL)

Marco Ladetto, Simone Ferrero, MD, Andrea Evangelista, PhD, Michael Mian, MD, Alice Di Rocco, Angela Coggi, Giuseppe Rossi, MD, Alessandro Re, MD, Vittorio Stefoni, Federica Cavallo, MD PhD, Annalisa Chiappella, MD, Armando Santoro, MD, Chiara Rusconi, Maria Gomes da Silva, MD, Manuel Gotti, MD, Anna Lia Molinari, MD, Filippo Ballerini, MD, Andres J M Ferreri, MD, Alberto Bosi, MD, Franco Narni, MD, Caterina Stelitano, MD, Alberto Zamò, MD, Gianni Ciccone, Umberto Vitolo, Maurizio Martelli, Sergio Cortelazzo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 401.
https://doi.org/10.1182/blood-2018-99-110289
Published: 2018
Journal Articles

The Engineered MIPI (e-MIPI), a Candidate Data-Mining Based Mantle Cell Lymphoma Prognostic Index Developed from the Dataset of the Fondazione Italiana Linfomi (FIL) MCL0208 Phase III Trial

Gian Maria Zaccaria, PhD, Simone Ferrero, MD, Roberto Passera, PhD, Andrea Evangelista, PhD, Mariella Loschirico, MD, Irene Dogliotti, MD, Marco Ghislieri, Elisa Genuardi, PhD, Riccardo Bomben, PhD, Valter Gattei, MD, Giovannino Ciccone, Monica Tani, MD, Gianluca Gaidano, MD PhD, Stefano Volpetti, MD, Maria Giuseppina Cabras, MD, Nicola Di Renzo, MD, Francesco Merli, MD, Daniele Vallisa, MD, Michele Spina, MD, Anna Pascarella, MD, Giancarlo Latte, MD, Caterina Patti, Gabriele Pozzato, MD, Alberto Fabbri, MD, Sergio Cortelazzo, MD, Marco Ladetto
Journal: Blood
Blood (2018) 132 (Supplement 1): 2890.
https://doi.org/10.1182/blood-2018-99-114168
Published: 2018
Journal Articles

Delphi, a Data Warehouse to Discover Associations between Variables in Clinical Trials: Application to the Fondazione Italiana Linfomi (FIL) MCL0208 Phase III Trial

Gian Maria Zaccaria, MSc, Simone Ferrero, Andrea Evangelista, Samanta Rosati, Cristina Castagneri, Marco Ghislieri, Barbero Daniela, Elisa Genuardi, Mariella Lo Schirico, Alberto Zamò, Umberto Vitolo, Riccardo Bomben, Valter Gattei, MD, Sara Galimberti, PhD MD, Antonello Di Paolo, Davide Rossi, MD PhD, Gianluca Gaidano, MD PhD, Alice Di Rocco, Sergio Cortelazzo, Mario Boccadoro, Gabriella Balestra, Marco Ladetto
Journal: Blood
Blood (2017) 130 (Supplement 1): 3451.
https://doi.org/10.1182/blood.V130.Suppl_1.3451.3451
Published: 2017
Journal Articles

Targeted Locus Amplification (TLA): A Novel Next Generation Sequencing (NGS) Technology to Detect New Molecular Markers and Monitoring Minimal Residual Disease (MRD) in Mantle Cell and Follicular Lymphoma

Elisa Genuardi, Petra Klous, Daniela Drandi, Barbara Mantoan, Luigia Monitillo, Barbero Daniela, Mehmet Yilmaz, Fabio Cattellino, Marika Vasta, Federica Furia, Gian Maria Zaccaria, MSc, Federica Cavallo, Sergio Cortelazzo, Umberto Vitolo, MD, Stefano Luminari, Massimo Federico, Mario Boccadoro, Erik Splinter, Marco Ladetto, Simone Ferrero
Journal: Blood
Blood (2017) 130 (Supplement 1): 2742.
https://doi.org/10.1182/blood.V130.Suppl_1.2742.2742
Published: 2017
Journal Articles

Final Results of Northern Italy Leukemia Group (NILG) Trial 10/07 Combining Pediatric-Type Therapy with Minimal Residual Disease Study and Risk-Oriented Hematopoietic Cell Transplantation in Adult Acute Lymphoblastic Leukemia (ALL)

Renato Bassan, MD, Arianna Masciulli, PharmD, Tamara Intermesoli, MD, Orietta Spinelli, PhD, Manuela Tosi, PhD, Chiara Pavoni, MSc, Ernesta Audisio, MD, Giuseppe Rossi, MD, Monica Fumagalli, MD, Vincenzo Cassibba, MD, Daniele Mattei, MD, Claudio Romani, MD, Agostino Cortelezzi, MD, Fabio Ciceri, MD, Anna Maria Scattolin, MD, Umberto Vitolo, MD, Erika Borlenghi, MD, Sergio Cortelazzo, MD, Andrea Gallamini, MD, Lorella Depaoli, MD, Leonardo Campiotti, MD, Monica Tajana, MD, Monica Bocchia, MD, Antonella Vitale, MD, Marco Ladetto, MD, Eros Di Bona, MD, Elena Oldani, BiolSc, Alessandro Rambaldi, MD
Journal: Blood
Blood (2016) 128 (22): 176.
https://doi.org/10.1182/blood.V128.22.176.176
Published: 2016
Journal Articles

Identification of DNA Copy Number Variations Associated with the Clinical Outcome in Young Mantle Cell Lymphoma Patients Treated with Cytarabine-Based High Dose Sequential Chemotherapy and Autologous Stem Cell Transplantation in the Prospective from the MCL0208 Phase III Trial from Fondazione Italiana Linfomi (FIL)

Andrea Rinaldi, PhD, Simone Ferrero, Ivo Kwee, PhD, Davide Rossi, MD PhD, Alessio Bruscaggin, Valeria Spina, Fary Diop, Filippo Ballerini, MD, Filippo Gherlinzoni, MD, Fabio Benedetti, Michael Mian, MD, Caterina Stelitano, MD, Elisa Doni, MD, Alessandra Flavia Salvi, Sergio Cortelazzo, Marco Ladetto, MD, Gianluca Gaidano, MD PhD, Francesco Bertoni, MD
Journal: Blood
Blood (2016) 128 (22): 4099.
https://doi.org/10.1182/blood.V128.22.4099.4099
Published: 2016
Journal Articles

Khorana Score and Histotype Predict the Incidence of Early Venous Thromboembolism (VTE) in Non Hodgkin Lymphoma (NHL). a Pooled Data Analysis of Twelve Clinical Trials of Fondazione Italiana Linfomi (FIL)

Roberto Mario Santi, Manuela Ceccarelli, Gioacchino Catania, Chiara Monagheddu, Andrea Evangelista, Elisa Bernocco, Federico Monaco, Massimo Federico, Umberto Vitolo, MD, Sergio Cortelazzo, Maria Giuseppina Cabras, Michele Spina, Luca Baldini, Carola Boccomini, Annalisa Chiappella, MD, Alessia Bari, Stefano Luminari, MD, Marco Calabrese, Alessandro Levis, MD, Laura Contino, Giovannino Ciccone, Marco Ladetto
Journal: Blood
Blood (2015) 126 (23): 3934.
https://doi.org/10.1182/blood.V126.23.3934.3934
Published: 2015
Journal Articles

Identification of a Novel Gene Expression Signature in Mantle Cell Lymphoma from the Fondazione Italiana Linfomi (FIL)-MCL-0208 Trial: A Focus on the B Cell Receptor Pathway

Riccardo Bomben, Simone Ferrero, Michele Dal Bo, Tiziana D'Agaro, Alessandro Re, Andrea Evangelista, Angelo Michele Carella, Alberto Zamò, Umberto Vitolo, MD, Paola Omedè, Chiara Rusconi, Luca Arcaini, Luigi Rigacci, Stefano Luminari, MD, Sergio Cortelazzo, Marco Ladetto, Valter Gattei, MD
Journal: Blood
Blood (2015) 126 (23): 701.
https://doi.org/10.1182/blood.V126.23.701.701
Published: 2015
Journal Articles

A Molecular Model for the Prediction of Progression Free Survival in Young Mantle Cell Lymphoma Patients Treated with Cytarabine-Based High Dose Sequential Chemotherapy and Autologous Stem Cell Transplantation: Results from the MCL0208 Phase III Trial from Fondazione Italiana Linfomi (FIL)

Davide Rossi, MD PhD, Simone Ferrero, Alessio Bruscaggin, Paola Ghione, Alice Di Rocco, Valeria Spina, Vittorio Stefoni, Giovannino Ciccone, Daniela Barbero, Luigia Monitillo, Maria Gomes Da Silva, Armando Santoro, MD, Annalia Molinari, Andres J.M. Ferreri, Sergio Cortelazzo, Marco Ladetto, Gianluca Gaidano
Journal: Blood
Blood (2015) 126 (23): 336.
https://doi.org/10.1182/blood.V126.23.336.336
Published: 2015
Journal Articles

The Long-Term Outcome Of Adult Patients With Acute Myeloid Leukemia NPM+ and FLT3/ITD- Is Not Significantly Improved By The Application Of An Allogeneic Stem Cell Transplantation

Tamara Intermesoli, MD, Marco Frigeni, MD, Elena Oldani, BiolSC, Pamela Zanghì, BiolSC, Orietta Spinelli, BiolSC, Alberto Bosi, MD, Filippo Marmont, MD, Giuseppe Rossi, Sergio Cortelazzo, MD, Alessandro Levis, Daniele Mattei, MD, Maria Pogliani Enrico Maria, MD, Anna Maria Scattolin, MD, Massimo Bernardi, MD, Giacomo Gianfaldoni, MD, Ernesta Audisio, MD, Arianna Masciulli, BiolSc, Renato Bassan, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2013) 122 (21): 2648.
https://doi.org/10.1182/blood.V122.21.2648.2648
Published: 2013
Journal Articles

Phase II Randomized Trial Of Radiation-Free Central Nervous System (CNS) Prophylaxis Comparing Intrathecal Triple Therapy With Liposomal Cytarabine (DepoCyte ® ) In Adult Acute Lymphoblastic Leukemia (ALL)

Renato Bassan, MD, Arianna Masciulli, BiolSc, Tamara Intermesoli, MD, Ernesta Audisio, MD, Chiara Cattaneo, MD, Enrico Maria Pogliani, MD, Vincenzo Cassibba, MD, Daniele Mattei, MD, Claudio Romani, MD, Agostino Cortelezzi, MD, Consuelo Corti, MD, Anna Maria Scattolin, MD, Orietta Spinelli, BiolSC, Manuela Tosi, BiolSC, Margherita Parolini, MD, Filippo Marmont, MD, Erika Borlenghi, MD, Monica Fumagalli, MD, Sergio Cortelazzo, MD, Andrea Gallamini, MD, Rosa Maria Marfisi, Elena Oldani, BiolSC, Roberto Marchioli, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2013) 122 (21): 3901.
https://doi.org/10.1182/blood.V122.21.3901.3901
Published: 2013
Journal Articles

Improved Igh-Based MRD Detection By Using Droplet Digital PCR: a Comparison With Real Time Quantitative PCR In MCL and MM

Daniela Drandi, Lenka Kubiczkovà, Nadia Dani, Simone Ferrero, Luigia Monitillo, Barbara Mantoan, Elisa Genuardi, Daniela Barbero, Manuela Gambella, Davide Barberio, Paola Ghione, Guglielmo Guarona, Elona Saraci, Paola Omedè, Roberto Passera, Roman Hajek, Sergio Cortelazzo, MD, Antonio Palumbo, Mario Boccadoro, MD, Giorgio Inghirami, Marco Ladetto
Journal: Blood
Blood (2013) 122 (21): 4290.
https://doi.org/10.1182/blood.V122.21.4290.4290
Published: 2013
Journal Articles

Blood Cells Dynamic and Thrombo-Haemorragic Events in Low Risk Essential Thrombocytosis Patients. A North Italian and Austrian Study.

Andrea Piccin, MD, PhD, Michael Steurer, MD, Manfred Mitterer, Elisabeth Blöchl, Luigi Marcheselli, Irene Pusceddu, Alessandra Marabese, Irene Bertozzi, Maria Luigia Randi, Elena Elli, Enrico Maria Pogliani, MD, Dino Veneri, Omar Perbellini, Enrica Pacquola, Michele Gottardi, Mario Tiribelli, Anna Guella, Barbara Inella, Paolo Vivaldi, Ercole De Biasi, Rosaria Sancetta, Renato Bassan, MD, Filippo Gherlinzoni, MD, Giovanni Pizzolo, MD, Gunther Gastl, Sergio Cortelazzo, MD
Journal: Blood
Blood (2012) 120 (21): 2839.
https://doi.org/10.1182/blood.V120.21.2839.2839
Published: 2012
Journal Articles

Validation of the Cibmtr Score in Predicting the Outcome of Hematopoietic Stem-Cell Transplantation in AML Patients Not in Complete Remission At the Time of Conditioning: A Retrospective Analysis On Behalf of the Gruppo Italiano Trapianto Di Midollo Osseo (GITMO)

Elisabetta Todisco, MD, Fabio Ciceri, MD, Elena Oldani, BiolSC, Maria Teresa Van Lint, MD, Irene Donnini, MD, Francesca Patriarca, MD, Emilio Paolo Alessandrino, MD, Francesca Bonifazi, MD, William Arcese, MD, Anna Paola Iori, Paola Marenco, MD, Elisabetta Terruzzi, MD, Sergio Cortelazzo, MD, Stella Santarone, MD, Anna Proia, MD, Paolo Corradini, MD, Elena Tagliaferri, MD, Sadia Falcioni, MD, Giuseppe Irrera, MD, Laura Dallanegra, MD, Luca Castagna, MD, Agnese Camboni, Alberto Bosi, MD, Andrea Bacigalupo, MD, Alessandro Rambaldi, MD
Journal: Blood
Blood (2012) 120 (21): 2005.
https://doi.org/10.1182/blood.V120.21.2005.2005
Published: 2012