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Eric Fischer
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Journal Articles

Loss of Negative Metabolic Feedback Drives TET2 Mutant Inflammation

Geon Geon Kim, Christopher B. Hergott, Aidan P. Miller, Amy Deik, Meaghan Boileau, Kevin Bullock, Kerry Pierce, Angelina Choy, Wesley Shin, Marie E McConkey, Justin CT Loke, Birgitta Ryback, Michael N Trinh, Justine Rutter, Hong Yue, Paul Park, Shourya SR Burman, Eric Fischer, Scott A Armstrong, Clary Clish, Benjamin Levine Ebert
Journal: Blood
Blood (2024) 144 (Supplement 1): 4060.
https://doi.org/10.1182/blood-2024-208145
Published: 2024
Journal Articles

Menin Inhibitor Induced Menin Protein Degradation Contributes to Menin Inhibitor Efficacy

Jevon Cutler, Jonathan Tsai, Brandon Regalado, Wallace Bourgeois, Daniela Wenge, Jeonghyeon Kim, Radoslaw Nowak, Elizabeth Ener, Katherine Donovan, Sarah Naomi Olsen, Eric Fischer, Benjamin L. Ebert, Scott A Armstrong
Journal: Blood
Blood (2023) 142 (Supplement 1): 2788.
https://doi.org/10.1182/blood-2023-184931
Published: 2023
Journal Articles

Prediction of PP2A Holoenzymes Guided By the Structural Characterization of Methylation Independent PP2A Assembly

Franziska Wachter, Radoslaw Nowak, Eric Fischer
Journal: Blood
Blood (2023) 142 (Supplement 1): 2802.
https://doi.org/10.1182/blood-2023-172895
Published: 2023
Journal Articles

Large-Scale Characterization and Functional Assessment of Adaptive Immunity in Patients with MGUS and SMM Reveals Significant Defects

Michelle P. Aranha, Romanos Sklavenitis-Pistofidis, Yoshinobu Konishi, Ting Wu, Hong Yue, Elizabeth D. Lightbody, Mahshid Rahmat, Michael Timonian, Daniel L. Mallory, Michael P. Agius, Shohreh Varmeh, Nang Kham Su, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Anna Justis, Radosław P. Nowak, Mark Hamilton, Daniel Auclair, Catherine R. Marinac, Eric Fischer, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 2548.
https://doi.org/10.1182/blood-2023-178062
Published: 2023
Journal Articles

Functional Characterization of E3 Ligases and Their Regulators: Therapeutic Implications for Development of New Proteolysis-Targeting Chimeric Degraders of Oncoproteins

Ryosuke Shirasaki, MD PhD, Sara Gandolfi, MD, Ricardo De Matos Simoes, PhD, Geoffrey M Matthews, PhD, Dennis Buckley, Joseline Raja, Quinlan L Sievers, PhD, Olga Dashevsky, PhD, Haley Poarch, Huihui Tang, PhD, Megan Bariteau, BSc, Michal Sheffer, PhD, Sondra L. Downey-Kopyscinski, PhD, Paul Hengeveld, Brian Glassner, PhD, Eugen Dhimolea, PhD, Christopher J. Ott, PhD, Tinghu Zhang, PhD, Nicholas P Kwiatkowski, PhD, Jacob P. Laubach, MD, Robert L. Schlossman, MD, Paul G. Richardson, MD, Aedin Culhane, PhD, Richard W.J. Groen, PhD, Eric Fischer, Benjamin L. Ebert, MD PhD, Francisca Vazquez, PhD, Aviad Tsherniak, PhD, William C. Hahn, MD PhD, Joan Levy, PhD, Daniel Auclair, Jonathan D. Licht, MD, Jonathan J Keats, PhD, Lawrence H. Boise, PhD, James Bradner, MD, Nathanael Gray, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 318.
https://doi.org/10.1182/blood-2019-130549
Published: 2019
Journal Articles

Triple Degradation of BTK, IKZF1 and IKZF3 in B-Cell Malignancies

Sara Morrow, BA, Dennis Dobrovolsky, PhD, Eric Wang, PhD, Radosław P. Nowak, PhD, Katherine Donovan, PhD, Tyler Faust, PhD, Guang Yang, PhD, Zhengnian Li, PhD, Eric Fischer, Steven P Treon, MD PhD FRCP, David M Weinstock, MD, Nathanael S. Gray, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 263.
https://doi.org/10.1182/blood-2018-99-116895
Published: 2018
Journal Articles

Genome-Scale Screen Reveals Genes Required for Lenalidomide-Mediated Degradation of Aiolos By CRL4-CRBN

Quinlan Sievers, BA, Jessica Gasser, PhD, Glenn Cowley, PhD, John G Doench, PhD, Eric Fischer, PhD, Benjamin L Ebert, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5139.
https://doi.org/10.1182/blood.V128.22.5139.5139
Published: 2016