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Marie E McConkey
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Journal Articles

In Vivo barcoded CRISPR-Cas9 Screen Identifies Ncoa4- mediated Ferritinophagy As a Dependence in Tet2 -Deficient Haemopoiesis

Justin CT Loke, Geon Geon Kim, Meaghan Boileau, Thuy T.P. Nguyen, Marie E McConkey, Aidan P. Miller, Wesley Shin, Christopher B. Hergott, Maria Ericsson, Anja E.H. Nordstrom, Scott A Armstrong, Joseph D Mancias, Benjamin Levine Ebert
Journal: Blood
Blood (2024) 144 (Supplement 1): 188.
https://doi.org/10.1182/blood-2024-200955
Published: 2024
Journal Articles

Loss of Negative Metabolic Feedback Drives TET2 Mutant Inflammation

Geon Geon Kim, Christopher B. Hergott, Aidan P. Miller, Amy Deik, Meaghan Boileau, Kevin Bullock, Kerry Pierce, Angelina Choy, Wesley Shin, Marie E McConkey, Justin CT Loke, Birgitta Ryback, Michael N Trinh, Justine Rutter, Hong Yue, Paul Park, Shourya SR Burman, Eric Fischer, Scott A Armstrong, Clary Clish, Benjamin Levine Ebert
Journal: Blood
Blood (2024) 144 (Supplement 1): 4060.
https://doi.org/10.1182/blood-2024-208145
Published: 2024
Journal Articles

The Effect of TET2 Loss on Macrophage Phagocytosis

Aidan Patrick Miller, Wesley Shin, Marie E McConkey, Justin CT Loke, Geon Geon Kim, Benjamin L. Ebert
Journal: Blood
Blood (2024) 144 (Supplement 1): 1291.
https://doi.org/10.1182/blood-2024-208226
Published: 2024
Journal Articles

PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy

Peter G. Miller, Adam S. Sperling, Christina Mayerhofer, Marie E. McConkey, Jana M. Ellegast, Carmen Da Silva, Drew N. Cohen, Chuqi Wang, Azeem Sharda, Ni Yan, Subha Saha, Cameron Schluter, Ilexa Schechter, Mikołaj Słabicki, Brittany Sandoval, Josephine Kahn, Steffen Boettcher, Christopher J. Gibson, David T. Scadden, Kimberly Stegmaier, Shruti Bhatt, R. Coleman Lindsley, Benjamin L. Ebert
Journal: Blood
Blood (2023) 142 (24): 2079–2091.
https://doi.org/10.1182/blood.2023020331
Published: 2023
Includes: Supplemental data
Journal Articles

In Vivo CRISPR Screening Platform for Studying Myeloid Inflammation and Clonal Dynamics

Peter Geon Kim, Christopher B. Hergott, Justin CT Loke, Wesley Shin, Marie E McConkey, Benjamin L. Ebert
Journal: Blood
Blood (2023) 142 (Supplement 1): 2699.
https://doi.org/10.1182/blood-2023-188939
Published: 2023
Journal Articles

Lenalidomide promotes the development of TP53 -mutated therapy-related myeloid neoplasms

Clinical Trials & Observations
Adam S. Sperling, Veronica A. Guerra, James A. Kennedy, Yuanqing Yan, Joanne I. Hsu, Feng Wang, Andrew T. Nguyen, Peter G. Miller, Marie E. McConkey, Vanessa A. Quevedo Barrios, Ken Furudate, Linda Zhang, Rashmi Kanagal-Shamanna, Jianhua Zhang, Latasha Little, Curtis Gumbs, Naval Daver, Courtney D. DiNardo, Tapan Kadia, Farhad Ravandi, Hagop Kantarjian, Guillermo Garcia-Manero, P. Andrew Futreal, Benjamin L. Ebert, Koichi Takahashi
Journal: Blood
Blood (2022) 140 (16): 1753–1763.
https://doi.org/10.1182/blood.2021014956
Published: 2022
Includes: Supplemental data
Journal Articles

Association of clonal hematopoiesis with chronic obstructive pulmonary disease

Peter G. Miller, Dandi Qiao, Joselyn Rojas-Quintero, Michael C. Honigberg, Adam S. Sperling, Christopher J. Gibson, Alexander G. Bick, Abhishek Niroula, Marie E. McConkey, Brittany Sandoval, Brian C. Miller, Weiwei Shi, Kaushik Viswanathan, Matthew Leventhal, Lillian Werner, Matthew Moll, Brian E. Cade, R. Graham Barr, Adolfo Correa, L. Adrienne Cupples, Sina A. Gharib, Deepti Jain, Stephanie M. Gogarten, Leslie A. Lange, Stephanie J. London, Ani Manichaikul, George T. O’Connor, Elizabeth C. Oelsner, Susan Redline, Stephen S. Rich, Jerome I. Rotter, Vasan Ramachandran, Bing Yu, Lynette Sholl, Donna Neuberg, Siddhartha Jaiswal, Bruce D. Levy, Caroline A. Owen, Pradeep Natarajan, Edwin K. Silverman, Peter van Galen, Yohannes Tesfaigzi, Michael H. Cho, Benjamin L. Ebert, for the COPDGene Study Investigators, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium
Journal: Blood
Blood (2022) 139 (3): 357–368.
https://doi.org/10.1182/blood.2021013531
Published: 2022
Includes: Supplemental data
Journal Articles

SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia

Brenton G. Mar, S. Haihua Chu, Josephine D. Kahn, Andrei V. Krivtsov, Richard Koche, Cecilia A. Castellano, Jacob L. Kotlier, Rebecca L. Zon, Marie E. McConkey, Jonathan Chabon, Ryan Chappell, Peter V. Grauman, James J. Hsieh, Scott A. Armstrong, Benjamin L. Ebert
Journal: Blood
Blood (2017) 130 (24): 2631–2641.
https://doi.org/10.1182/blood-2017-03-775569
Published: 2017
Includes: Supplemental data
Journal Articles

Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation

Ofir Wolach, MD, Rob S Sellar, MD, Kimberly Martinod, PhD, Marie E. McConkey, PhD, Alexander J. Silver, B.S., Ryan Chappell, Richard M. Stone, MD, Martha Wadleigh, MD, David P Steensma, MD, Daniel J. DeAngelo, MD PhD, Ilene Galinsky, MSN, ANPc, Rebekka K. Schneider, MD, Robert F. Padera, MD PhD, Ann Mullally, MD, Denisa D. Wagner, PhD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2016) 128 (22): 633.
https://doi.org/10.1182/blood.V128.22.633.633
Published: 2016
Journal Articles

Cooperating Effect of Rps14 , Csnk1a1 and miRNA145/miRNA146a Haploinsufficiency in the Activation of the Innate Immune System in Del(5q) MDS

Schneider K. Rebekka, MD, Monica Schenone, PhD, Monica Ferreira Ventura, PhD, Fabian Beier, MD, Tim H. Bruemmendorf, MD, Ulrich Germing, MD, Uwe Platzbecker, MD, Guntram Büsche, MD, Marie E. McConkey, PhD, Christopher S Waters, R. Coleman Lindsley, MDPhD, Benjamin L. Ebert, MD
Journal: Blood
Blood (2015) 126 (23): 356.
https://doi.org/10.1182/blood.V126.23.356.356
Published: 2015
Journal Articles

Reduced Protein Synthesis and p53 Activation in Late-Stage Erythroblasts Mediate the Erythroid Differentiation Defect in Mice with Ribosomal Protein S14 Haploinsufficiency

Rebekka K. Schneider, MD, Marie E. McConkey, PhD, Lisa P. Chu, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1892.
https://doi.org/10.1182/blood.V124.21.1892.1892
Published: 2014
Journal Articles

Mutant Splicing Factor 3b Subunit 1 (SF3B1) Causes Dysregulated Erythropoiesis and a Stem Cell Disadvantage

Esther A. Obeng, MDPhD, Marie E. McConkey, PhD, Dean Campagna, Rebekka K. Schneider, MD, Michelle C. Chen, Paul J Schmidt, PhD, Ann Mullally, MD, Mark D. Fleming, MD DPhil, Benjamin L. Ebert, MD DPhil
Journal: Blood
Blood (2014) 124 (21): 828.
https://doi.org/10.1182/blood.V124.21.828.828
Published: 2014
Journal Articles

Lenalidomide Induces Ubiquitination and Degradation of CSNK1A1 in MDS with Del(5q)

Emma C. Fink, Jan Krönke, MD, Slater N. Hurst, Namrata D. Udeshi, PhD, Tanya Svinkina, Rebekka K. Schneider, MD, Marie E. McConkey, PhD, Marcus Järås, PhD, Lars Bullinger, MD PhD, Steven A. Carr, PhD, Benjamin L. Ebert, MD DPhil
Journal: Blood
Blood (2014) 124 (21): 4.
https://doi.org/10.1182/blood.V124.21.4.4
Published: 2014