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Azeem Sharda
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Journal Articles

PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy

Peter G. Miller, Adam S. Sperling, Christina Mayerhofer, Marie E. McConkey, Jana M. Ellegast, Carmen Da Silva, Drew N. Cohen, Chuqi Wang, Azeem Sharda, Ni Yan, Subha Saha, Cameron Schluter, Ilexa Schechter, Mikołaj Słabicki, Brittany Sandoval, Josephine Kahn, Steffen Boettcher, Christopher J. Gibson, David T. Scadden, Kimberly Stegmaier, Shruti Bhatt, R. Coleman Lindsley, Benjamin L. Ebert
Journal: Blood
Blood (2023) 142 (24): 2079–2091.
https://doi.org/10.1182/blood.2023020331
Published: 2023
Includes: Supplemental data
Journal Articles

Cap-Independent Protein Translation in Hematopoiesis

Michael Mazzola, Ting Zhao, Karin Gustafsson, Trine Kristiansen, Giulia Schiroli, Jelena Milosevic, Youmna Kfoury, Tsuyoshi Fukushima, Anna Kiem, Azeem Sharda, Hiroki Kato, David Sykes, Pavel Ivanov, Vijay G. Sankaran, David T. Scadden
Journal: Blood
Blood (2022) 140 (Supplement 1): 1983–1984.
https://doi.org/10.1182/blood-2022-170506
Published: 2022
Journal Articles

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers

Rushdia Zareen Yusuf, Borja Saez, Azeem Sharda, Nick van Gastel, Vionnie W. C. Yu, Ninib Baryawno, Elizabeth W. Scadden, Sanket Acharya, Shrikanta Chattophadhyay, Cherrie Huang, Vasanthi Viswanathan, Dana S'aulis, Julien Cobert, David B. Sykes, Mark A. Keibler, Sudeshna Das, John N. Hutchinson, Michael Churchill, Siddhartha Mukherjee, Dongjun Lee, Francois Mercier, John Doench, Lars Bullinger, David J. Logan, Stuart Schreiber, Gregory Stephanopoulos, William B. Rizzo, David T. Scadden
Journal: Blood
Blood (2020) 136 (11): 1303–1316.
https://doi.org/10.1182/blood.2019001808
Published: 2020
Includes: Supplemental data
Journal Articles

The Distinctive Metabolic Environment of the Bone Marrow Niche Drives Leukemia Chemoresistance

Nick van Gastel, PhD, Jessica B. Spinelli, PhD, Azeem Sharda, MS, Amir Schajnovitz, PhD, Ninib Baryawno, PhD, Catherine S Rhee, PhD, Toshihiko Oki, MD PhD, Eliane Grace, Heather J. Soled, Charles Vidoudez, PhD, Sunia A. Trauger, PhD, Marcia C. Haigis, PhD, David T. Scadden, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3725.
https://doi.org/10.1182/blood-2019-124789
Published: 2019
Journal Articles

Untargeted Metabolomics Identifies Glutamine Metabolism As a Driver of Chemoresistance in Acute Myeloid Leukemia

Nick van Gastel, PhD, Amir Schajnovitz, PhD, Charles Vidoudez, PhD, Toshihiko Oki, MD PhD, Azeem Sharda, MS, Sunia A. Trauger, PhD, David T. Scadden, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2523.
https://doi.org/10.1182/blood.V130.Suppl_1.2523.2523
Published: 2017