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Giulia Schiroli
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Journal Articles

Delivery of Gene Writers In Vivo to Hematopoietic Stem Cells and T Cells Using Targeted and Untargeted Lipid Nanoparticles (LNP)

Michael T. Monte, Lorenzo Tozzi, Rahul Palchaudhuri, Apiwat Wangweerawong, Yaser Heshmati, Giulia Schiroli, Han Gu, Yu Cao, William E. Salomon, Anne Bothmer, Jason Rodriguez, Mohit Gupta, James B. Rottman, William Querbes, Cecilia Cotta-Ramusino, Michael C Holmes, Hari Pujar, Z. Jane Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2197.
https://doi.org/10.1182/blood-2024-208968
Published: 2024
Journal Articles

In Vivo HSC Gene Editing for Correction of the Sickle Cell Mutation Using RNA Gene Writers

Lorenzo Tozzi, Giulia Schiroli, Yaser Heshmati, Yu Cao, Michael T. Monte, Apiwat Wangweerawong, James B. Rottman, Rahul Palchaudhuri, Jean-Antoine Ribeil, John Manis, Hari Pujar, William Querbes, Anne Bothmer, Cecilia Cotta-Ramusino, Z. Jane Wang, William E. Salomon, Michael C Holmes
Journal: Blood
Blood (2024) 144 (Supplement 1): 515.
https://doi.org/10.1182/blood-2024-208626
Published: 2024
Journal Articles

Modulating mRNA Translation Fidelity As a Novel Mechanism for AML Chemoresistance

Christina Mayerhofer, Dan Li, Trine A. Kristiansen, Ernst Mayerhofer, Azeem Sharda, Lingli He, Michael Mazzola, Giulia Schiroli, Karin Gustafsson, Sam Keyes, Anna Kiem, Eve Crompton, Yanxin Xu, Zhixun Dou, Charles Vidoudez, Peter G. Miller, Nick Van Gastel, David Scadden
Journal: Blood
Blood (2024) 144 (Supplement 1): 2727.
https://doi.org/10.1182/blood-2024-205125
Published: 2024
Journal Articles

In Vivo Delivery of RNA By Lipid Nanoparticles (LNP) to Hematopoietic Stem Cells and T Cells in Humanized Mice and Non-Human Primates

Michael T. Monte, Han Gu, Laura Saunders, Mohit Gupta, Lei Liu, Apiwat Wangweerawong, Thomas V. Colace, Aaron Zannini, Lorenzo Tozzi, Yu Cao, Giulia Schiroli, William E. Salomon, James B. Rottman, Rahul Palchaudhuri, Ulrike Gerdemann, Lev Gorfinkel, Francesca Alvarez Calderon, Leslie Kean, Hari Pujar, Z. Jane Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4818.
https://doi.org/10.1182/blood-2023-187271
Published: 2023
Journal Articles

Deploying an RNA-Based Gene Writer System and Lipid Nanoparticle (LNP) Delivery to Generate Functional Chimeric Antigen Receptor (CAR) T Cells with in Vitro and In Vivo Anti-Tumor Activity

Michael S Magee, Alberto De Iaco, Jason Rodriguez, James B. Rottman, Donghui Liu, Giulia Schiroli, Pooja Sabhachandani, Yu Cao, Rebecca Levy, Mohit Gupta, Michael T. Monte, Jane Wang, Bill Querbes, Cecilia Cotta-Ramusino, Madhusudan V Peshwa, Michael C Holmes
Journal: Blood
Blood (2023) 142 (Supplement 1): 2073.
https://doi.org/10.1182/blood-2023-184755
Published: 2023
Journal Articles

Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors

Catherine Rhee, Elizabeth W. Scadden, Lai Ping Wong, Giulia Schiroli, Michael C. Mazzola, Phillip L. Chea, Hiroki Kato, Friedrich F. Hoyer, Meeta Mistry, Bum-Kyu Lee, Jonghwan Kim, Matthias Nahrendorf, Michael K. Mansour, David B. Sykes, Ruslan I. Sadreyev, David T. Scadden
Journal: Blood
Blood (2023) 142 (7): 658–674.
https://doi.org/10.1182/blood.2023020257
Published: 2023
Includes: Supplemental data
Journal Articles

Cap-Independent Protein Translation in Hematopoiesis

Michael Mazzola, Ting Zhao, Karin Gustafsson, Trine Kristiansen, Giulia Schiroli, Jelena Milosevic, Youmna Kfoury, Tsuyoshi Fukushima, Anna Kiem, Azeem Sharda, Hiroki Kato, David Sykes, Pavel Ivanov, Vijay G. Sankaran, David T. Scadden
Journal: Blood
Blood (2022) 140 (Supplement 1): 1983–1984.
https://doi.org/10.1182/blood-2022-170506
Published: 2022
Journal Articles

Rigidity of Cell Fate and Function Among Monocytes

Catherine Rhee, Elizabeth W Scadden, Lai Ping Wong, Giulia Schiroli, Michael Mazzola, Phillip Chea, Hiroki Kato, Friedrich F Hoyer, Meeta Mistry, Bum-Kyu Lee, Jonghwan Kim, Matthias Nahrendorf, Michael K Mansour, David Sykes, Ruslan I Sadreyev, David T. Scadden
Journal: Blood
Blood (2021) 138 (Supplement 1): 2057.
https://doi.org/10.1182/blood-2021-151110
Published: 2021
Journal Articles

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

Sara Mastaglio, Pietro Genovese, Zulma Magnani, Eliana Ruggiero, Elisa Landoni, Barbara Camisa, Giulia Schiroli, Elena Provasi, Angelo Lombardo, Andreas Reik, Nicoletta Cieri, Martina Rocchi, Giacomo Oliveira, Giulia Escobar, Monica Casucci, Bernhard Gentner, Antonello Spinelli, Anna Mondino, Attilio Bondanza, Luca Vago, Maurilio Ponzoni, Fabio Ciceri, Michael C. Holmes, Luigi Naldini, Chiara Bonini
Journal: Blood
Blood (2017) 130 (5): 606–618.
https://doi.org/10.1182/blood-2016-08-732636
Published: 2017
Includes: Supplemental data
Journal Articles

NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD

Sara Mastaglio, MD, Pietro Genovese, PhD, Zulma Magnani, MSc, Elisa Landoni, Barbara Camisa, BSc, Giulia Schiroli, Elena Provasi, PhD, Angelo Lombardo, PhD, Andreas Reik, PhD, Nicoletta Cieri, MD PhD, Maurilio Ponzoni, Fabio Ciceri, MD, Claudio Bordignon, MD, Michael C. Holmes, PhD, Philip D Gregory, PhD, Luigi Naldini, MD PhD, Chiara Bonini, MD
Journal: Blood
Blood (2014) 124 (21): 308.
https://doi.org/10.1182/blood.V124.21.308.308
Published: 2014