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Journal Articles

Epitope Editing Combined with Extended Schedule Anti-KIT Antibody Treatment Allows Immune-Based In Vivo Selection of Multiplex Genome-Engineered Cells

Gabriele Casirati, Adele Mucci, Marta Freschi, Andrea Cosentino, Mohammed S Mahmoud, Jing Zeng, Nola Neri, Christian Brendel, Daniel Bauer, Pietro Genovese

Blood (2024) 144 (Supplement 1): 4767.

https://doi.org/10.1182/blood-2024-202480

Published: 2024

Journal Articles

The Association of SEPTIN6 Mutations with Pediatric Myelodysplasia

Safa F Mohamad, Meaghan McGuinness, Gabriele Casirati, Chad Everett Harris, Raffaele Renella, Pietro Genovese, Eric Allenspach, David A. Williams

Blood (2023) 142 (Supplement 1): 1846.

https://doi.org/10.1182/blood-2023-182069

Published: 2023

Journal Articles

Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia

Gabriele Casirati, Andrea Cosentino, Adele Mucci, Mohammed S Mahmoud, Iratxe Ugarte Zabala, Jing Zeng, Scott Ficarro, Denise Klatt, Christian Brendel, Alessandro Rambaldi, Jerome Ritz, Jarrod Marto, Danilo Pellin, Daniel E. Bauer, Scott A Armstrong, Pietro Genovese

Blood (2023) 142 (Supplement 1): 7130.

https://doi.org/10.1182/blood-2023-189980

Published: 2023

Journal Articles

Epitope Edited Hematopoietic Stem Cells Allow Immune-Based In Vivo Selection of Genome-Engineered Cells

Gabriele Casirati, Andrea Cosentino, Adele Mucci, Mohammed S Mahmoud, Marta Freschi, Jing Zeng, Christian Brendel, Daniel E. Bauer, Pietro Genovese

Blood (2023) 142 (Supplement 1): 7127.

https://doi.org/10.1182/blood-2023-177772

Published: 2023

Journal Articles

Epitope Engineered Hematopoietic Stem and Progenitor Cells to Enable CAR-T Cell Immunotherapy for Acute Myeloid Leukemia

Gabriele Casirati, Andrea Cosentino, Adele Mucci, Iraxte Ugarte Zabala, Mohammed S. Mahmoud, Christian Brendel, Alessandro Rambaldi, Jerome Ritz, Scott A. Armstrong, Pietro Genovese

Blood (2022) 140 (Supplement 1): 303–304.

https://doi.org/10.1182/blood-2022-167285

Published: 2022

Journal Articles

Septin-6 Regulates Murine and Human Hematopoiesis, and Its Dysregulation Is Associated with Pediatric Myelodysplasia

Safa F Mohamad, Meaghan McGuinness, Gabriele Casirati, Alejo E Rodriguez-Fraticelli, Chad E. Harris, Fernando D. Camargo, Pietro Genovese, Eric J Allenspach, David A. Williams

Blood (2022) 140 (Supplement 1): 8588–8589.

https://doi.org/10.1182/blood-2022-163606

Published: 2022

Journal Articles

Towards Clinical Translation of Hematopoietic Cell Gene Editing for Treating Hyper-IgM Type 1

Valentina Vavassori, Elisabetta Mercuri, Genni Marcovecchio, Maria Carmina Castiello, Daniele Canarutto, Claudia Asperti, Aurelien Jacob, Luisa Albano, Elena Fontana, Eugenio Scanziani, Marina Radrizzani, Anna Villa, Pietro Genovese, Luigi Naldini

Blood (2021) 138 (Supplement 1): 3978.

https://doi.org/10.1182/blood-2021-148572

Published: 2021

Journal Articles

Generation of Memory Stem T Cells Specific for Tumor Antigens and Resistant to Inhibitory Signals By Genome Editing

Beatrice Claudia Cianciotti, Alessia Potenza, Valentina Vavassori, Zulma Magnani, Luigi Naldini, MD PhD, Fabio Ciceri, MD, Pietro Genovese, PhD, Eliana Ruggiero, PhD, Chiara Bonini, MD

Blood (2018) 132 (Supplement 1): 2202.

https://doi.org/10.1182/blood-2018-99-118201

Published: 2018

Journal Articles

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

Blood (2017) 130 (5): 606–618.

https://doi.org/10.1182/blood-2016-08-732636

Published: 2017

Includes: Supplemental data

Journal Articles

NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD

Sara Mastaglio, MD, Pietro Genovese, PhD, Zulma Magnani, MSc, Elisa Landoni, Barbara Camisa, BSc, Giulia Schiroli, Elena Provasi, PhD, Angelo Lombardo, PhD, Andreas Reik, PhD, Nicoletta Cieri, MD PhD, Maurilio Ponzoni, Fabio Ciceri, MD, Claudio Bordignon, MD, Michael C. Holmes, PhD, Philip D Gregory, PhD, Luigi Naldini, MD PhD, Chiara Bonini, MD

Blood (2014) 124 (21): 308.

https://doi.org/10.1182/blood.V124.21.308.308

Published: 2014

Journal Articles

TCR Gene Editing Achieved In a Single Round Of T Cell Activation Is Sufficient To Redirect T Cell Specificity and Prevent GvHD

Sara Mastaglio, MD, Pietro Genovese, PhD, Zulma Magnani, MSc, Elena Provasi, PhD, Angelo Lombardo, PhD, Andreas Reik, Nicoletta Cieri, MD, Fabio Ciceri, Claudio Bordignon, MD, Michael C. Holmes, PhD, Philip D Gregory, PhD, Luigi Naldini, MD, PhD, Chiara Bonini, MD

Blood (2013) 122 (21): 2898.

https://doi.org/10.1182/blood.V122.21.2898.2898

Published: 2013

Journal Articles

Off-Tumor Target Expression Levels Do Not Predict CAR-T Cell Killing: A Foundation For The Safety Of CD44v6-Targeted T Cells

Monica Casucci, PhD, Benedetta Nicolis di Robilant, MSc, Laura Falcone, MSc, Barbara Camisa, BSc, Margherita Norelli, Bsc, Bernhard Gentner, MD, Pietro Genovese, PhD, Maurilio Ponzoni, MD, Aurore Saudemont, PhD, Claudio Bordignon, MD, Luigi Naldini, MD, PhD, Fabio Ciceri, MD, Gianpietro Dotti, MD, Chiara Bonini, MD, Attilio Bondanza, MD, PhD

Blood (2013) 122 (21): 142.

https://doi.org/10.1182/blood.V122.21.142.142

Published: 2013

Journal Articles

CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma

Monica Casucci, Benedetta Nicolis di Robilant, Laura Falcone, Barbara Camisa, Margherita Norelli, Pietro Genovese, Bernhard Gentner, Fabiana Gullotta, Maurilio Ponzoni, Massimo Bernardi, Magda Marcatti, Aurore Saudemont, Claudio Bordignon, Barbara Savoldo, Fabio Ciceri, Luigi Naldini, Gianpietro Dotti, Chiara Bonini, Attilio Bondanza

Blood (2013) 122 (20): 3461–3472.

https://doi.org/10.1182/blood-2013-04-493361

Published: 2013

Includes: Supplemental data

Journal Articles

Co-Expression of a Suicide Gene in CAR-Redirected T Cells Enables the Safe Targeting of CD44v6 for Leukemia and Myeloma Eradication

Monica Casucci, PhD, Benedetta Nicolis di Robilant, MSc, Laura Falcone, MSc, Barbara Camisa, BSc, Pietro Genovese, PhD, Bernhard Gentner, MD $, Luigi Naldini, MD, PhD, Barbara Savoldo, MD, PhD, Fabio Ciceri, MD, Claudio Bordignon, MD, Gianpietro Dotti, MD, Chiara Bonini, MD, Attilio Bondanza, MD, PhD

Blood (2012) 120 (21): 949.

https://doi.org/10.1182/blood.V120.21.949.949

Published: 2012

Journal Articles

TCR Gene Editing Results in Effective Immunotherapy of Leukemia without the Development of GvHD

Blood (2011) 118 (21): 667.

https://doi.org/10.1182/blood.V118.21.667.667

Published: 2011

Journal Articles

Dual Transgenesis of T Cells with a Novel CD44v6-Specific Chimeric Antigen Receptor and a Suicide Gene for Safe and Effective Targeting of Chemoresistance in Hematopoietic Tumors

Monica Casucci, Laura Falcone, Benedetta Nicolis di Robilant, Barbara Camisa, BSc, Pietro Genovese, Bernhard Gentner, MD, Luigi Naldini, MD, PhD, Barbara Savoldo, Fabio Ciceri, M.D., Claudio Bordignon, MD, Gianpietro Dotti, MD, Chiara Bonini, Attilio Bondanza, MD, PhD

Blood (2011) 118 (21): 3125.

https://doi.org/10.1182/blood.V118.21.3125.3125

Published: 2011

Journal Articles

Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia.

Elena Provasi, PhD, Pietro Genovese, Angelo Lombardo, Zulma Magnani, Andreas Reik, Pei-Qi Liu, Victoria Chu, Jurgen Kuball, Attilio Bondanza, Giulia Casorati, Fabio Ciceri, Claudio Bordignon, MD, Philip D. Greenberg, Michael C. Holmes, Philip D. Gregory, Luigi Naldini, Chiara Bonini

Blood (2010) 116 (21): 3764.

https://doi.org/10.1182/blood.V116.21.3764.3764

Published: 2010

Journal Articles

From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia.

Elena Provasi, Pietro Genovese, Zulma Magnani, Oscar Muniz Pello, Jurgen Kuball, Angelo Lombardo, Attilio Bondanza, Philip D. Gregory, Claudio Bordignon, Michael C. Holmes, Philip D. Greenberg, Luigi Naldini, Chiara Bonini

Blood (2009) 114 (22): 374.

https://doi.org/10.1182/blood.V114.22.374.374

Published: 2009

NARROW

Epitope Editing Combined with Extended Schedule Anti-KIT Antibody Treatment Allows Immune-Based In Vivo Selection of Multiplex Genome-Engineered Cells

The Association of SEPTIN6 Mutations with Pediatric Myelodysplasia

Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia

Epitope Edited Hematopoietic Stem Cells Allow Immune-Based In Vivo Selection of Genome-Engineered Cells

Epitope Engineered Hematopoietic Stem and Progenitor Cells to Enable CAR-T Cell Immunotherapy for Acute Myeloid Leukemia

Septin-6 Regulates Murine and Human Hematopoiesis, and Its Dysregulation Is Associated with Pediatric Myelodysplasia

Towards Clinical Translation of Hematopoietic Cell Gene Editing for Treating Hyper-IgM Type 1

Generation of Memory Stem T Cells Specific for Tumor Antigens and Resistant to Inhibitory Signals By Genome Editing

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD

TCR Gene Editing Achieved In a Single Round Of T Cell Activation Is Sufficient To Redirect T Cell Specificity and Prevent GvHD

Off-Tumor Target Expression Levels Do Not Predict CAR-T Cell Killing: A Foundation For The Safety Of CD44v6-Targeted T Cells

CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma

Co-Expression of a Suicide Gene in CAR-Redirected T Cells Enables the Safe Targeting of CD44v6 for Leukemia and Myeloma Eradication

TCR Gene Editing Results in Effective Immunotherapy of Leukemia without the Development of GvHD

Dual Transgenesis of T Cells with a Novel CD44v6-Specific Chimeric Antigen Receptor and a Suicide Gene for Safe and Effective Targeting of Chemoresistance in Hematopoietic Tumors

Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia.

From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia.

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American Society of Hematology

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American Society of Hematology

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