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Journal Articles

The Association of SEPTIN6 Mutations with Pediatric Myelodysplasia

Safa F Mohamad, Meaghan McGuinness, Gabriele Casirati, Chad Everett Harris, Raffaele Renella, Pietro Genovese, Eric Allenspach, David A. Williams

Blood (2023) 142 (Supplement 1): 1846.

https://doi.org/10.1182/blood-2023-182069

Published: 2023

Journal Articles

Septin11 and Septin 8 Play Critical and Overlapping Roles Murine Stem Cell Function

Safa F Mohamad, Meaghan McGuinness, Chad Everett Harris, David A. Williams

Blood (2023) 142 (Supplement 1): 5583.

https://doi.org/10.1182/blood-2023-181991

Published: 2023

Journal Articles

Septin-6 Regulates Murine and Human Hematopoiesis, and Its Dysregulation Is Associated with Pediatric Myelodysplasia

Safa F Mohamad, Meaghan McGuinness, Gabriele Casirati, Alejo E Rodriguez-Fraticelli, Chad E. Harris, Fernando D. Camargo, Pietro Genovese, Eric J Allenspach, David A. Williams

Blood (2022) 140 (Supplement 1): 8588–8589.

https://doi.org/10.1182/blood-2022-163606

Published: 2022

Journal Articles

Small Molecule Inhibition of PDE6D-RAS Interaction Suppresses the Growth of Acute Lymphoblastic Leukemia Cell Lines

Sara Canovas Nunes, Haiming Xu, Serena De Vita, Andrew Anighoro, Francois Autelitano, Edward Beaumont, Pamela Klingbeil, Meaghan McGuinness, Beatrice Duvert, Chad E. Harris, Lu Yang, Sheela Pangeni Pokharel, Chun-Wei David Chen, Monika Ermann, David A. Williams

Blood (2021) 138 (Supplement 1): 1199.

https://doi.org/10.1182/blood-2021-147009

Published: 2021

Journal Articles

Fetal Erythropoiesis Is Defective in Rpl11 Heterozygous Mice and Increases in Severity in Young Animals

Dolly Thomas, PhD, Cailin Joyce, PhD, Robert A. Redd, MS, Bertil Glader, MD, Steven Ellis, PhD, Donna S. Neuberg, ScD, Meaghan McGuinness, BS, Colin A. Sieff, MB, BCh, Carl D. Novina, MD PhD

Blood (2017) 130 (Supplement 1): 872.

https://doi.org/10.1182/blood.V130.Suppl_1.872.872

Published: 2017

Journal Articles

Vav1, a Rho GTPase Guanine Exchange Factor (GEF) Is Required to Integrate gp130 Cytokine Signaling for Successful Engraftment of Murine Hematopoietic Stem Cells Following Irradiation

Serena De Vita, MD PhD, Yanhua Li, MD PhD, Chad Everett Harris, MS, Meaghan McGuinness, BS, David A. Williams, MD

Blood (2016) 128 (22): 2149.

https://doi.org/10.1182/blood.V128.22.2149.2149

Published: 2016

Journal Articles

A Novel Conditional Knockout of the Diamond Blackfan Anemia Gene Rpl11 Shows Failure of Erythropoiesis, a Marked Increase in BFU-E Progenitors By Phenotype That Proliferate Poorly in Culture, and Activation of p53 Target Genes

Cailin E Joyce, PhD, Meaghan McGuinness, BS, Rebekka K Schneider, MD, Mark D. Fleming, MD DPhil, Dean R Campagna, BS, Paul J Schmidt, PhD, Benjamin L Ebert, MD PhD, Carl D. Novina, MDPhD, Colin A. Sieff, MB.BCh

Blood (2015) 126 (23): 1205.

https://doi.org/10.1182/blood.V126.23.1205.1205

Published: 2015

Journal Articles

Kinase Activity Of Pak2, An Effector Of Rac/CDC42 and Its Interaction With β-PIX Is Required For Murine Hematopoietic Stem Cell Shape, F-Actin Formation, Directional Migration In Vitro and For HSPC Homing To Bone Marrow In Vivo

Pavankumar N.G. Reddy, PhD, Jenna Wood, Chad E Harris, Ke Xu, Meaghan McGuinness, Maria Radu, MD PhD, Rachelle Kosoff, Jonathan Chernoff, MD, PhD, David A. Williams, MD

Blood (2013) 122 (21): 2419.

https://doi.org/10.1182/blood.V122.21.2419.2419

Published: 2013

Journal Articles

Vav1 Deficiency Differentially Affects Engraftment of Fetal Hematopoietic Organs During Development Compared with Adult Marrow After Transplantation

Serena De Vita, MD, PhD, Chad E Harris, Raffaele Renella, MD, PhD, Ronald Mathieu, Meaghan McGuinness, David A. Williams, MD

Blood (2012) 120 (21): 1212.

https://doi.org/10.1182/blood.V120.21.1212.1212

Published: 2012

Journal Articles

Pak A Proteins Are Essential for Hematopoietic Stem/Progenitor Cell (HSC/P) Engraftment Through Regulation of Signaling Pathways Controlling HSC/P Proliferation, Survival, Migration, and the Actin Cytoskeleton

Adrienne M. Dorrance, PhD, Rachelle Kosoff, Meaghan McGuinness, Chad Harris, Serena De Vita, MD, PhD, Ronald Mathieu, Steven W. Lane, MD, Michael D. Milsom, PhD, Jonathan Chernoff, MD, PhD, David A. Williams, MD

Blood (2011) 118 (21): 917.

https://doi.org/10.1182/blood.V118.21.917.917

Published: 2011

NARROW

The Association of SEPTIN6 Mutations with Pediatric Myelodysplasia

Septin11 and Septin 8 Play Critical and Overlapping Roles Murine Stem Cell Function

Septin-6 Regulates Murine and Human Hematopoiesis, and Its Dysregulation Is Associated with Pediatric Myelodysplasia

Small Molecule Inhibition of PDE6D-RAS Interaction Suppresses the Growth of Acute Lymphoblastic Leukemia Cell Lines

Fetal Erythropoiesis Is Defective in Rpl11 Heterozygous Mice and Increases in Severity in Young Animals

Vav1, a Rho GTPase Guanine Exchange Factor (GEF) Is Required to Integrate gp130 Cytokine Signaling for Successful Engraftment of Murine Hematopoietic Stem Cells Following Irradiation

A Novel Conditional Knockout of the Diamond Blackfan Anemia Gene Rpl11 Shows Failure of Erythropoiesis, a Marked Increase in BFU-E Progenitors By Phenotype That Proliferate Poorly in Culture, and Activation of p53 Target Genes

Kinase Activity Of Pak2, An Effector Of Rac/CDC42 and Its Interaction With β-PIX Is Required For Murine Hematopoietic Stem Cell Shape, F-Actin Formation, Directional Migration In Vitro and For HSPC Homing To Bone Marrow In Vivo

Vav1 Deficiency Differentially Affects Engraftment of Fetal Hematopoietic Organs During Development Compared with Adult Marrow After Transplantation

Pak A Proteins Are Essential for Hematopoietic Stem/Progenitor Cell (HSC/P) Engraftment Through Regulation of Signaling Pathways Controlling HSC/P Proliferation, Survival, Migration, and the Actin Cytoskeleton

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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