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Journal Articles

Generation of Memory Stem T Cells Specific for Tumor Antigens and Resistant to Inhibitory Signals By Genome Editing

Beatrice Claudia Cianciotti, Alessia Potenza, Valentina Vavassori, Zulma Magnani, Luigi Naldini, MD PhD, Fabio Ciceri, MD, Pietro Genovese, PhD, Eliana Ruggiero, PhD, Chiara Bonini, MD

Blood (2018) 132 (Supplement 1): 2202.

https://doi.org/10.1182/blood-2018-99-118201

Published: 2018

Journal Articles

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

Blood (2017) 130 (5): 606–618.

https://doi.org/10.1182/blood-2016-08-732636

Published: 2017

Includes: Supplemental data

Journal Articles

NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD

Sara Mastaglio, MD, Pietro Genovese, PhD, Zulma Magnani, MSc, Elisa Landoni, Barbara Camisa, BSc, Giulia Schiroli, Elena Provasi, PhD, Angelo Lombardo, PhD, Andreas Reik, PhD, Nicoletta Cieri, MD PhD, Maurilio Ponzoni, Fabio Ciceri, MD, Claudio Bordignon, MD, Michael C. Holmes, PhD, Philip D Gregory, PhD, Luigi Naldini, MD PhD, Chiara Bonini, MD

Blood (2014) 124 (21): 308.

https://doi.org/10.1182/blood.V124.21.308.308

Published: 2014

Journal Articles

TCR Gene Editing Achieved In a Single Round Of T Cell Activation Is Sufficient To Redirect T Cell Specificity and Prevent GvHD

Sara Mastaglio, MD, Pietro Genovese, PhD, Zulma Magnani, MSc, Elena Provasi, PhD, Angelo Lombardo, PhD, Andreas Reik, Nicoletta Cieri, MD, Fabio Ciceri, Claudio Bordignon, MD, Michael C. Holmes, PhD, Philip D Gregory, PhD, Luigi Naldini, MD, PhD, Chiara Bonini, MD

Blood (2013) 122 (21): 2898.

https://doi.org/10.1182/blood.V122.21.2898.2898

Published: 2013

Journal Articles

Early Reconstitution of T-Cell Immunity to CMV After HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is a Strong Surrogate Biomarker for Lower Non-Relapse Mortality Rates

Maddalena Noviello, MSc, Alessandra Forcina, MD, Maria Teresa Lupo Stanghellini, MD, Matteo Carrabba, MD, Andrea Assanelli, MD, Maria Rosaria Carbone, MSc, Zulma Magnani, MSc, Consuelo Corti, MD, Massimo Bernardi, MD, Jacopo Peccatori, MD, Fabio Ciceri, MD, Chiara Bonini, MD, Attilio Bondanza, MD, PhD

Blood (2012) 120 (21): 4191.

https://doi.org/10.1182/blood.V120.21.4191.4191

Published: 2012

Journal Articles

TCR Gene Editing Results in Effective Immunotherapy of Leukemia without the Development of GvHD

Blood (2011) 118 (21): 667.

https://doi.org/10.1182/blood.V118.21.667.667

Published: 2011

Journal Articles

The Importance of Be(ginn)Ing Naïve: Implications for Cancer Immune-Gene Therapy

Nicoletta Cieri, MD, Barbara Camisa, Fabienne Cocchiarella, Elena Provasi, PhD, Zulma Magnani, Attilio Bondanza, MD, PhD, Anna Mondino, PhD, Fulvio Mavilio, PhD, Silvio Bicciato, PhD, Alessandra Recchia, PhD, Chiara Bonini

Blood (2011) 118 (21): 2052.

https://doi.org/10.1182/blood.V118.21.2052.2052

Published: 2011

Journal Articles

Memory T Cells Masquerading as Naïve Cells: Implications on Adoptive T Cell Immunotherapy.

Nicoletta Cieri, Elena Provasi, Barbara Camisa, Zulma Magnani, Attilio Bondanza, Chiara Bonini, MD

Blood (2010) 116 (21): 1471.

https://doi.org/10.1182/blood.V116.21.1471.1471

Published: 2010

Journal Articles

Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia.

Elena Provasi, PhD, Pietro Genovese, Angelo Lombardo, Zulma Magnani, Andreas Reik, Pei-Qi Liu, Victoria Chu, Jurgen Kuball, Attilio Bondanza, Giulia Casorati, Fabio Ciceri, Claudio Bordignon, MD, Philip D. Greenberg, Michael C. Holmes, Philip D. Gregory, Luigi Naldini, Chiara Bonini

Blood (2010) 116 (21): 3764.

https://doi.org/10.1182/blood.V116.21.3764.3764

Published: 2010

Journal Articles

From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia.

Elena Provasi, Pietro Genovese, Zulma Magnani, Oscar Muniz Pello, Jurgen Kuball, Angelo Lombardo, Attilio Bondanza, Philip D. Gregory, Claudio Bordignon, Michael C. Holmes, Philip D. Greenberg, Luigi Naldini, Chiara Bonini

Blood (2009) 114 (22): 374.

https://doi.org/10.1182/blood.V114.22.374.374

Published: 2009

Journal Articles

Leukemic Dendritic Cells Expand Central Memory T Lymphocytes From HCT Donors Able to React against the Original Leukemia in Vitro and In Vivo.

Monica Casucci, Serena Kimi Perna, Attilio Bondanza, Zulma Magnani, Massimo Bernardi, Alessandro Crotta, Cristina Tresoldi, Katharina Fleischhauer, Elena Provasi, Maurilio Ponzoni, Federico Caligaris-Cappio, Fabio Ciceri, Claudio Bordignon, Alessandro Cignetti, Chiara Bonini

Blood (2009) 114 (22): 4090.

https://doi.org/10.1182/blood.V114.22.4090.4090

Published: 2009

Journal Articles

T Cell Receptor Gene Transfer into Naive and Central Memory Lymphocytes by Lentiviral Vectors for a Safe and Effective Adoptive Immune Therapy of Leukemia

Elena Provasi, Oscar Muniz Pello, Zulma Magnani, Jurgen Kuball, Angelo Lombardo, Attilio Bondanza, Philip D. Gregory, Claudio Bordignon, Michael C. Holmes, Phil D. Greenberg, Luigi Naldini, Chiara Bonini

Blood (2008) 112 (11): 3529.

https://doi.org/10.1182/blood.V112.11.3529.3529

Published: 2008

Journal Articles

Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality

Blood (2008) 112 (11): 353.

https://doi.org/10.1182/blood.V112.11.353.353

Published: 2008

Journal Articles

Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans

Simona Piemontese, Zulma Magnani, Jacopo Peccatori, MD, Claudio Bordignon, Chiara Bonini, Fabio Ciceri, M.D., Attilio Bondanza

Blood (2008) 112 (11): 1180.

https://doi.org/10.1182/blood.V112.11.1180.1180

Published: 2008

Journal Articles

Leukemic Blasts Secondary to Myelodysplastic Syndromes Are Molecularly Programmed To Differentiate into Functionally Mature Dendritic Cells.

Serena K. Perna, MD, Monica Casucci, BSc, Attilio Bondanza, MD, PhD, Zulma Magnani, BSc, Massimo Bernardi, MD, Alessandro Crotta, MD, Alessandro Cignetti, MD, Ferderico Caligaris Cappio, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD

Blood (2007) 110 (11): 1801.

https://doi.org/10.1182/blood.V110.11.1801.1801

Published: 2007

Journal Articles

Antitumor effects of HSV-TK–engineered donor lymphocytes after allogeneic stem-cell transplantation

Fabio Ciceri, Chiara Bonini, Sarah Marktel, Elisabetta Zappone, Paolo Servida, Massimo Bernardi, Alessandra Pescarollo, Attilio Bondanza, Jacopo Peccatori, Silvano Rossini, Zulma Magnani, Monica Salomoni, Claudia Benati, Maurilio Ponzoni, Luciano Callegaro, Paolo Corradini, Marco Bregni, Catia Traversari, Claudio Bordignon

Blood (2007) 109 (11): 4698–4707.

https://doi.org/10.1182/blood-2006-05-023416

Published: 2007

Journal Articles

The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies

Catia Traversari, Sarah Marktel, Zulma Magnani, Patrizia Mangia, Vincenzo Russo, Fabio Ciceri, Chiara Bonini, Claudio Bordignon

Blood (2007) 109 (11): 4708–4715.

https://doi.org/10.1182/blood-2006-04-015230

Published: 2007

Journal Articles

Rapid and Wide Immunereconstitution Obtained with HSV-TK Engineered Donor Lymphocyte Add-Backs Permits Long-Term Survival after haplo-HSCT.

Blood (2006) 108 (11): 307.

https://doi.org/10.1182/blood.V108.11.307.307

Published: 2006

Journal Articles

Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes

Attilio Bondanza, Veronica Valtolina, Zulma Magnani, Maurilio Ponzoni, Katharina Fleischhauer, Mark Bonyhadi, Catia Traversari, Francesca Sanvito, Salvatore Toma, Marina Radrizzani, Simona La Seta-Catamancio, Fabio Ciceri, Claudio Bordignon, Chiara Bonini

Blood (2006) 107 (5): 1828–1836.

https://doi.org/10.1182/blood-2005-09-3716

Published: 2006

Journal Articles

Receptor Repertoire Reconstitution Suggests Acquisition of Patient-Specific Tolerance by Natural Killer Cells Arising from Hematopoietic Progenitor Stem Cells after Haploidentical Transplantation.

Luca Vago, MD, Simona Di Terlizzi, BS, Elisabetta Zino, BS, Chiara F. Magnani, BS, Maria T. Lupo Stanghellini, MD, Zulma Magnani, PhD, Benedetta Mazzi, BS, Daniela Clerici, MD, Attilio Bondanza, MD, Marco Bregni, MD, Silvano Rossini, MD, Jacopo Peccatori, MD, Chiara Bonini, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Katharina Fleischhauer, MD

Blood (2005) 106 (11): 2905.

https://doi.org/10.1182/blood.V106.11.2905.2905

Published: 2005

NARROW

Generation of Memory Stem T Cells Specific for Tumor Antigens and Resistant to Inhibitory Signals By Genome Editing

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD

TCR Gene Editing Achieved In a Single Round Of T Cell Activation Is Sufficient To Redirect T Cell Specificity and Prevent GvHD

Early Reconstitution of T-Cell Immunity to CMV After HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is a Strong Surrogate Biomarker for Lower Non-Relapse Mortality Rates

TCR Gene Editing Results in Effective Immunotherapy of Leukemia without the Development of GvHD

The Importance of Be(ginn)Ing Naïve: Implications for Cancer Immune-Gene Therapy

Memory T Cells Masquerading as Naïve Cells: Implications on Adoptive T Cell Immunotherapy.

Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia.

From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia.

Leukemic Dendritic Cells Expand Central Memory T Lymphocytes From HCT Donors Able to React against the Original Leukemia in Vitro and In Vivo.

T Cell Receptor Gene Transfer into Naive and Central Memory Lymphocytes by Lentiviral Vectors for a Safe and Effective Adoptive Immune Therapy of Leukemia

Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality

Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans

Leukemic Blasts Secondary to Myelodysplastic Syndromes Are Molecularly Programmed To Differentiate into Functionally Mature Dendritic Cells.

Antitumor effects of HSV-TK–engineered donor lymphocytes after allogeneic stem-cell transplantation

The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies

Rapid and Wide Immunereconstitution Obtained with HSV-TK Engineered Donor Lymphocyte Add-Backs Permits Long-Term Survival after haplo-HSCT.

Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes

Receptor Repertoire Reconstitution Suggests Acquisition of Patient-Specific Tolerance by Natural Killer Cells Arising from Hematopoietic Progenitor Stem Cells after Haploidentical Transplantation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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