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Journal Articles

Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

Megan D. Hoban, Gregory J. Cost, Matthew C. Mendel, Zulema Romero, Michael L. Kaufman, Alok V. Joglekar, Michelle Ho, Dianne Lumaquin, David Gray, Georgia R. Lill, Aaron R. Cooper, Fabrizia Urbinati, Shantha Senadheera, Allen Zhu, Pei-Qi Liu, David E. Paschon, Lei Zhang, Edward J. Rebar, Andrew Wilber, Xiaoyan Wang, Philip D. Gregory, Michael C. Holmes, Andreas Reik, Roger P. Hollis, Donald B. Kohn
Journal: Blood
Blood (2015) 125 (17): 2597–2604.
https://doi.org/10.1182/blood-2014-12-615948
Published: 2015
Includes: Supplemental data
Journal Articles

Targeted Gene Modification In Hematopoietic Stem Cells: A Potential Treatment For Thalassemia and Sickle Cell Anemia

Andreas Reik, PhD, Kai-Hsin Chang, PhD, Sandra Stehling-Sun, PhD, Yuanyue Zhou, Gary K Lee, PhD, Lynn Truong, Travis Wood, Ziying Zhang, Albert Luong, Andy Chan, Pei-Qi Liu, PhD, Jeffrey C Miller, PhD, David E Paschon, PhD, Dmitry Y Guschin, PhD, Lei Zhang, PhD, Evangelia Yannaki, MD, Martin A Giedlin, PhD, Edward J Rebar, PhD, Philip D Gregory, PhD, Fyodor D Urnov, PHD, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD, DSci
Journal: Blood
Blood (2013) 122 (21): 434.
https://doi.org/10.1182/blood.V122.21.434.434
Published: 2013
Journal Articles

A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR

Hiroki Torikai, Andreas Reik, Pei-Qi Liu, Yuanyue Zhou, Ling Zhang, Sourindra Maiti, Helen Huls, Jeffrey C. Miller, Partow Kebriaei, Brian Rabinovitch, Dean A. Lee, Richard E. Champlin, Chiara Bonini, Luigi Naldini, Edward J. Rebar, Philip D. Gregory, Michael C. Holmes, Laurence J. N. Cooper
Journal: Blood
Blood (2012) 119 (24): 5697–5705.
https://doi.org/10.1182/blood-2012-01-405365
Published: 2012
Includes: Supplemental data
Journal Articles

TCR Gene Editing Results in Effective Immunotherapy of Leukemia without the Development of GvHD

Elena Provasi, PhD, Pietro Genovese, Angelo Lombardo, PhD, Zulma Magnani, Pei-Qi Liu, Andreas Reik, Victoria Chu, David E Paschon, Lei Zhang, Jurgen Kuball, MD, PhD, Barbara Camisa, Attilio Bondanza, MD, PhD, Giulia Casorati, PhD, Maurilio Ponzoni, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Philip D. Greenberg, MD, Michael C. Holmes, PhD, Philip D. Gregory, PhD, Luigi Naldini, MD, PhD, Chiara Bonini, MD
Journal: Blood
Blood (2011) 118 (21): 667.
https://doi.org/10.1182/blood.V118.21.667.667
Published: 2011
Journal Articles

Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia.

Elena Provasi, PhD, Pietro Genovese, Angelo Lombardo, Zulma Magnani, Andreas Reik, Pei-Qi Liu, Victoria Chu, Jurgen Kuball, Attilio Bondanza, Giulia Casorati, Fabio Ciceri, Claudio Bordignon, MD, Philip D. Greenberg, Michael C. Holmes, Philip D. Gregory, Luigi Naldini, Chiara Bonini
Journal: Blood
Blood (2010) 116 (21): 3764.
https://doi.org/10.1182/blood.V116.21.3764.3764
Published: 2010
Journal Articles

Targeted Killing of Glioblastoma Multiforme In Vivo by IL-13 Zetakine Redirected CTLs Made Glucocorticoid Resistant with Zinc Finger Nucleases.

Andreas Reik, PhD, Michael C. Holmes, PhD, Yuanyue Zhou, Matthew Mendel, Pei-Qi Liu, PhD, Gary Lee, PhD, David Paschon, PhD, Edward Rebar, PhD, Dale Ando, MD, David DiGiusto, PhD, Philip D. Gregory, PhD, Michael C. Jensen, MD
Journal: Blood
Blood (2007) 110 (11): 2597.
https://doi.org/10.1182/blood.V110.11.2597.2597
Published: 2007
Journal Articles

“Designer” Cells for Cellular Immunotherapy: Zinc Finger Nuclease (ZFN) Stimulated Targeted Recombination for the Simultaneous Disruption of the Endogenous Glucocorticoid Receptor and Site-Specific Addition of the IL13-Zetakine.

Andreas Reik, PhD, Michael C. Holmes, Ph.D., Fyodor D. Urnov, Ph.D., Yuanyue Zhou, Matthew Mendel, Pei-Qi Liu, Ph.D., Erica Moehle, Edward J. Rebar, Ph.D., Jeffrey C. Miller, Ph.D., Dale Ando, M.D., Philip D. Gregory, Ph.D., Michael Jensen, M.D.
Journal: Blood
Blood (2006) 108 (11): 3705.
https://doi.org/10.1182/blood.V108.11.3705.3705
Published: 2006