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Journal Articles

Single Cell Transcriptomics to Characterize the Features of Bone Marrow Natural Killer Cells in Different Relapse Modalities

Pier Rovatti, Marco Punta, Giorgio Orofino, Matteo Maria Naldini, Matteo Giovanni Carrabba, Massimo Bernardi, Jacopo Peccatori, Bernhard Gentner, Fabio Ciceri, Luca Vago, Cristina Toffalori

Blood (2024) 144 (Supplement 1): 929.

https://doi.org/10.1182/blood-2024-205896

Published: 2024

Journal Articles

Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis

Blood (2024) 143 (19): 1937–1952.

https://doi.org/10.1182/blood.2023022666

Published: 2024

Includes: Supplemental data

Journal Articles

Inflammation Shapes the Transcriptional Landscape of the Bone Marrow Microenvironment in Post-Transplantation Leukemia Relapses

Pier Rovatti, Marco Punta, Giorgio Orofino, Matteo Maria Naldini, Matteo Giovanni Carrabba, Massimo Bernardi, Jacopo Peccatori, Bernhard Gentner, Fabio Ciceri, Luca Vago, Cristina Toffalori

Blood (2023) 142 (Supplement 1): 3578.

https://doi.org/10.1182/blood-2023-189715

Published: 2023

Journal Articles

Genetic Engineering of Hematopoietic Progenitor Stem Cells for Targeted IFN-α Immunotherapy Reprogramming the Solid Tumor Microenvironment: A First-in-Man Study in Glioblastoma Multiforme (NCT03866109)

Blood (2023) 142 (Supplement 1): 4850.

https://doi.org/10.1182/blood-2023-178212

Published: 2023

Journal Articles

Unveiling the Biological Role of Peripheral Blood Human Circulating Hematopoietic Stem and Progenitor Cells

Blood (2022) 140 (Supplement 1): 1977–1978.

https://doi.org/10.1182/blood-2022-163251

Published: 2022

Journal Articles

Adaptive Routes of Hematopoietic Stem Cell Differentiation to Disease Conditions and Age in Gene Therapy Patients

Blood (2022) 140 (Supplement 1): 1904–1905.

https://doi.org/10.1182/blood-2022-162195

Published: 2022

Journal Articles

Reprogramming Macrophages Using Autologous Hematopoietic Stem Cells As Immunotherapy for Glioblastoma: TEM-GBM Study (NCT03866109)

Blood (2022) 140 (Supplement 1): 4575–4576.

https://doi.org/10.1182/blood-2022-165975

Published: 2022

Journal Articles

TEM-GBM: An Open-Label, Phase I/IIa Dose-Escalation Study Evaluating the Safety and Efficacy of Genetically Modified Tie-2 Expressing Monocytes to Deliver IFN-α within Glioblastoma Tumor Microenvironment

Blood (2021) 138 (Supplement 1): 2844.

https://doi.org/10.1182/blood-2021-150230

Published: 2021

Journal Articles

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Elisa Sala, MD, Francesca Biavasco, MD, Gabriele Bucci, PhD, Cristina Toffalori, PhD, Donatella Biancolini, PhD, Elena Antonini, MSc, Matteo Giovanni Carrabba, MD, Bernhard Gentner, MD, Cristina Tresoldi, MSc, Massimo Bernardi, MD, Dejan Lazarevic, MD, Giovanni Tonon, MD, Fabio Ciceri, MD, Luca Vago, MD PhD

Blood (2019) 134 (Supplement_1): 511.

https://doi.org/10.1182/blood-2019-124725

Published: 2019

Journal Articles

Extensive Metabolic Correction of Hurler Disease By Hematopoietic Stem Cell-Based Gene Therapy: Preliminary Results from a Phase I/II Trial

Bernhard Gentner, MD, Maria Ester Bernardo, MD PhD, Francesca Tucci, MD, Erika Zonari, PhD, Francesca Fumagalli, MD, Silvia Pontesilli, MD, Serena Acquati, PhD, Paolo Silvani, MD, Fabio Ciceri, MD, Attilio Rovelli, MD, Giancarlo La Marca, PhD, Rossella Parini, MD, Silvia Gregori, PhD, Eugenio Montini, PhD, Luigi Naldini, MD PhD, Alessandro Aiuti, MD PhD

Blood (2019) 134 (Supplement_1): 607.

https://doi.org/10.1182/blood-2019-128805

Published: 2019

Journal Articles

TEM-MM-101: A Phase I/IIa Dose Escalation Study Evaluating the Safety and Activity of Autologous CD34+ Enriched Hematopoietic Progenitor Cells Genetically Modified for Human Interferon-α2 in Multiple Myeloma Patients with Early Relapse after Intensive Front Line Therapy

Bernhard Gentner, MD, Francesca Farina, MD, Matteo Giovanni Carrabba, MD, Magda Marcatti, MD, Stefania Girlanda, MD, Gabriele Antonarelli, MD, Capotondo Alessia, PhD, Stefania Mazzoleni, PhD, Carlo Russo, MD, Luigi Naldini, MD PhD, Fabio Ciceri, MD

Blood (2019) 134 (Supplement_1): 2064.

https://doi.org/10.1182/blood-2019-123749

Published: 2019

Journal Articles

Longitudinal Tracking of Acute Myeloid Leukemia Stem Cells in Xenografts and Patients By microRNA Reporters and Single Cell RNA Sequencing

Matteo Maria Naldini, Gabriele Casirati, MD, Matteo Barcella, PhD, Stefano Beretta, PhD, Ivan Merelli, PhD, Carolina Caserta, Giacomo Desantis, PhD, Francesca Pavesi, MD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2019) 134 (Supplement_1): 916.

https://doi.org/10.1182/blood-2019-131167

Published: 2019

Journal Articles

Dissecting Ex Vivo Expansion of Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells By Single Cell RNA Sequencing

Matteo Maria Naldini, Gabriele Casirati, MD, Erika Zonari, PhD, Giacomo Desantis, PhD, Andrea Cammarata, PhD, Stefano Beretta, PhD, Ivan Merelli, PhD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 3343.

https://doi.org/10.1182/blood-2018-99-111879

Published: 2018

Journal Articles

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Nadia Foligno, Giacomo Desantis, PhD, Fabio Ciceri, MD, Davide Cittaro, PhD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 2834.

https://doi.org/10.1182/blood-2018-99-115101

Published: 2018

Journal Articles

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

Blood (2018) 131 (5): 533–545.

https://doi.org/10.1182/blood-2017-10-812859

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Distinct MiR-126 Expression Describes a Non-Genetic but Functional Intra-Tumoral Heterogeneity in Primary Human B-ALL and Can be Prospectively Used to Identify Aggressive Subclones in NSG Mice

Carolina Caserta, MS, Matteo Maria Naldini, MD, Silvia Nucera, MD, Davide Cittaro, Giacomo Desantis, Francesca Pavesi, MD, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2017) 130 (Supplement 1): 35.

https://doi.org/10.1182/blood.V130.Suppl_1.35.35

Published: 2017

Journal Articles

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

Blood (2017) 130 (5): 606–618.

https://doi.org/10.1182/blood-2016-08-732636

Published: 2017

Includes: Supplemental data

Journal Articles

microRNA-126 Orchestrates a Stem Cell-like Program in AML and B-ALL and Can be Exploited to Dissect Disease Heterogeneity

Francesca Pavesi, MD, Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Andrea Cosentino, Giacomo Desantis, PhD, Jose Garcia-Manteiga, PhD, Matteo Carrabba, MD, Massimo Bernardi, MD, Luca Vago, MD PhD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2016) 128 (22): 736.

https://doi.org/10.1182/blood.V128.22.736.736

Published: 2016

Journal Articles

Incremental Innovation of Ex Vivo Hematopoietic Stem Cell Engineering to Expand Clinical Gene Therapy Applications

Erika Zonari, PhD, Giacomo Desantis, PhD, Carolina Petrillo, Oriana Meo, Samantha Scaramuzza, PhD, Maria Rosa Lidonnici, PhD, Anna Kajaste-Rudnitski, PhD, Fabio Ciceri, MD, Sarah Marktel, Alessandro Aiuti, MD PhD, Giuliana Ferrari, PhD, Luigi Naldini, MD PhD, Bernhard Gentner, MD

Blood (2016) 128 (22): 4707.

https://doi.org/10.1182/blood.V128.22.4707.4707

Published: 2016

Journal Articles

Human CD34 + Cells from Different Sources Disclose a Specific Stemness Signature

Maria Rosa Lidonnici, PhD, Annamaria Aprile, PhD, Marta Frittoli, MD, Giacomo Mandelli, PhD, Ylenia Paleari, PhD, Antonello Spinelli, Bernhard Gentner, MD, Matilde Zambelli, Cristina Parisi, Laura Bellio, MD, Elena Cassinerio, MD, Laura Zanaboni, MD, Maria Domenica Cappellini, Fabio Ciceri, MD, Sarah Marktel, MD, Giuliana Ferrari, PhD

Blood (2016) 128 (22): 4709.

https://doi.org/10.1182/blood.V128.22.4709.4709

Published: 2016

NARROW

Single Cell Transcriptomics to Characterize the Features of Bone Marrow Natural Killer Cells in Different Relapse Modalities

Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis

Inflammation Shapes the Transcriptional Landscape of the Bone Marrow Microenvironment in Post-Transplantation Leukemia Relapses

Genetic Engineering of Hematopoietic Progenitor Stem Cells for Targeted IFN-α Immunotherapy Reprogramming the Solid Tumor Microenvironment: A First-in-Man Study in Glioblastoma Multiforme (NCT03866109)

Unveiling the Biological Role of Peripheral Blood Human Circulating Hematopoietic Stem and Progenitor Cells

Adaptive Routes of Hematopoietic Stem Cell Differentiation to Disease Conditions and Age in Gene Therapy Patients

Reprogramming Macrophages Using Autologous Hematopoietic Stem Cells As Immunotherapy for Glioblastoma: TEM-GBM Study (NCT03866109)

TEM-GBM: An Open-Label, Phase I/IIa Dose-Escalation Study Evaluating the Safety and Efficacy of Genetically Modified Tie-2 Expressing Monocytes to Deliver IFN-α within Glioblastoma Tumor Microenvironment

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Extensive Metabolic Correction of Hurler Disease By Hematopoietic Stem Cell-Based Gene Therapy: Preliminary Results from a Phase I/II Trial

TEM-MM-101: A Phase I/IIa Dose Escalation Study Evaluating the Safety and Activity of Autologous CD34+ Enriched Hematopoietic Progenitor Cells Genetically Modified for Human Interferon-α2 in Multiple Myeloma Patients with Early Relapse after Intensive Front Line Therapy

Longitudinal Tracking of Acute Myeloid Leukemia Stem Cells in Xenografts and Patients By microRNA Reporters and Single Cell RNA Sequencing

Dissecting Ex Vivo Expansion of Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells By Single Cell RNA Sequencing

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

Distinct MiR-126 Expression Describes a Non-Genetic but Functional Intra-Tumoral Heterogeneity in Primary Human B-ALL and Can be Prospectively Used to Identify Aggressive Subclones in NSG Mice

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease

microRNA-126 Orchestrates a Stem Cell-like Program in AML and B-ALL and Can be Exploited to Dissect Disease Heterogeneity

Incremental Innovation of Ex Vivo Hematopoietic Stem Cell Engineering to Expand Clinical Gene Therapy Applications

Human CD34 + Cells from Different Sources Disclose a Specific Stemness Signature

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American Society of Hematology

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ASH Publications

American Society of Hematology

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