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Yaser Heshmati
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Journal Articles

In Vivo correction of the sickle cell disease mutation in hematopoietic stem cells using RNA gene writers

Free
Yaser Heshmati, Giulia Schiroli, Lorenzo Tozzi, Michael Monte, Nouhaila Beytour, Apiwat Wangweerawong, James Rottman, William E. Salomon, Rahul Palchaudhuri, Z. Jane Wang, Anne Bothmer, Kim Vanuytsel, John Manis, Lev Gorfinkel, Francesca Alvarez Calderon, Ulrike Gerdemann, Leslie Kean, Hari Pujar, Cecilia Cotta-Ramusino, Raja Prince-Eladnani, Michael C Holmes
Journal: Blood
Blood (2025) 146 (Supplement 1): 2536.
https://doi.org/10.1182/blood-2025-2536
Published: 2025
Journal Articles

In Vivo RNA delivery by targeted lipid nanoparticles enable gene editing in hematopoietic stem cells and T cells

Free
Rahul Palchaudhuri, Michael Monte, Mohit Gupta, Giulia Schiroli, Lorenzo Tozzi, Lei Liu, Han Gu, Rebecca Goldman, Apiwat Wangweerawong, Aaron Zannini, Yaser Heshmati, Christina Ferren, Alyssa Sanfilippo, Tiffany Morales, Jessica Desmond, Kartika Venugopal, Jason Rodriguez, Albert De Iaco, Cecilia Cotta-Ramusino, William E. Salomon, James Rottman, William Querbes, Hari Pujar, Michael C Holmes, Z. Jane Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 4318.
https://doi.org/10.1182/blood-2025-4318
Published: 2025
Journal Articles

Delivery of Gene Writers In Vivo to Hematopoietic Stem Cells and T Cells Using Targeted and Untargeted Lipid Nanoparticles (LNP)

Free
Michael T. Monte, Lorenzo Tozzi, Rahul Palchaudhuri, Apiwat Wangweerawong, Yaser Heshmati, Giulia Schiroli, Han Gu, Yu Cao, William E. Salomon, Anne Bothmer, Jason Rodriguez, Mohit Gupta, James B. Rottman, William Querbes, Cecilia Cotta-Ramusino, Michael C Holmes, Hari Pujar, Z. Jane Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2197.
https://doi.org/10.1182/blood-2024-208968
Published: 2024
Journal Articles

In Vivo HSC Gene Editing for Correction of the Sickle Cell Mutation Using RNA Gene Writers

Free
Lorenzo Tozzi, Giulia Schiroli, Yaser Heshmati, Yu Cao, Michael T. Monte, Apiwat Wangweerawong, James B. Rottman, Rahul Palchaudhuri, Jean-Antoine Ribeil, John Manis, Hari Pujar, William Querbes, Anne Bothmer, Cecilia Cotta-Ramusino, Z. Jane Wang, William E. Salomon, Michael C Holmes
Journal: Blood
Blood (2024) 144 (Supplement 1): 515.
https://doi.org/10.1182/blood-2024-208626
Published: 2024
Journal Articles

Transcriptional Immunoediting of AML Cells after Allogeneic Hematopoietic Stem Cell Transplantation

Free
Kenneth Eagle, Taku Harada, Jeremie Kalfon, Monika Perez, Yaser Heshmati, Jazmin Ewers, Kimberly Stegmaier, Stuart H. Orkin, Maxim Pimkin
Journal: Blood
Blood (2021) 138 (Supplement 1): 647.
https://doi.org/10.1182/blood-2021-151180
Published: 2021
Journal Articles

Identification of CHD4 As a Potential Therapeutic Target of Acute Myeloid Leukemia

Free
Yaser Heshmati, Gözde Turköz, Aditya Harisankar, Sten Linnarsson, Marios Dimitriou, Indranil Sinha, Sören Lehmann, Hong Qian, PhD, Julian Walfridsson
Journal: Blood
Blood (2016) 128 (22): 1648.
https://doi.org/10.1182/blood.V128.22.1648.1648
Published: 2016
Journal Articles

Mesenchymal Stromal Cells, Instigator or Suppressor for the Development of MLL-AF9 Induced Acute Myeloid Leukemia?

Free
Pingnan Xiao, MD, Yaser Heshmati, Thibault Bouderlique, PhD, Makoto Kondo, PhD, Monika Dolinska, MSc, Lakshmi Sandhow, MSc, Anne-Sofie Johansson, PhD, Julian Walfridsson, Hong Qian, PhD
Journal: Blood
Blood (2016) 128 (22): 1488.
https://doi.org/10.1182/blood.V128.22.1488.1488
Published: 2016