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Brenton G. Mar
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Journal Articles

Pure Pathologic Response Is Associated with Improved Overall Survival in Patients with Advanced Systemic Mastocytosis Receiving Avapritinib in the Phase I EXPLORER Study

Jason Gotlib, MD MS, Deepti H. Radia, MRCPI, FRCPath, Tracy I. George, MD, William A Robinson, MD PhD, Albert T. Quiery, MD, Mark W. Drummond, PhD FRCPath, Prithviraj Bose, MD, Elizabeth O. Hexner, MD, Elliott F. Winton, MD, Hans-Peter Horny, Prof, Dr, Meera Tugnait, PhD, Oleg Schmidt-Kittler, PhD, Erica K. Evans, PhD, Hui-Min Lin, PhD, Brenton G. Mar, MD PhD, Michael W. Deininger, MD PhD, Daniel J. DeAngelo, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-137413
Published: 2020
Journal Articles

Frequency and Prognostic Significance of Recurrent Gene Mutations in Pediatric B-ALL: Report from the DFCI ALL Consortium

Giacomo Gotti, MD, Maneka Puligandla, MS, Kristen E. Stevenson, MS, Brenton G. Mar, MD PhD, Barbara L Asselin, MD, Uma Athale, MD MBBS, MSc, Luis A. Clavell, MD, Peter D. Cole, MD, Lisa M. Gennarini, MD, Justine M. Kahn, MDMSc, Kara M. Kelly, MD, Caroline Laverdiere, MD FRCPC, Jean-Marie Leclerc, Bruno Michon, MD FRCPC, Marshall A. Schorin, MD, Maria L. Sulis, MD, Thai Hoa Tran, MD, Jennifer J.G. Welch, MD, Kimberly Stegmaier, MD, Marian H. Harris, MD PhD, Lewis B. Silverman, MD, Yana Pikman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-136190
Published: 2020
Journal Articles

SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia

Brenton G. Mar, S. Haihua Chu, Josephine D. Kahn, Andrei V. Krivtsov, Richard Koche, Cecilia A. Castellano, Jacob L. Kotlier, Rebecca L. Zon, Marie E. McConkey, Jonathan Chabon, Ryan Chappell, Peter V. Grauman, James J. Hsieh, Scott A. Armstrong, Benjamin L. Ebert
Journal: Blood
Blood (2017) 130 (24): 2631–2641.
https://doi.org/10.1182/blood-2017-03-775569
Published: 2017
Includes: Supplemental data
Journal Articles

The relative utilities of genome-wide, gene panel, and individual gene sequencing in clinical practice

Clinical Trials & Observations
Frank C. Kuo, Brenton G. Mar, R. Coleman Lindsley, Neal I. Lindeman
Journal: Blood
Blood (2017) 130 (4): 433–439.
https://doi.org/10.1182/blood-2017-03-734533
Published: 2017
Journal Articles

The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia

Hubo Li, Brenton G. Mar, Huadi Zhang, Rishi V. Puram, Francisca Vazquez, Barbara A. Weir, William C. Hahn, Benjamin Ebert, David Pellman
Journal: Blood
Blood (2017) 129 (4): 497–508.
https://doi.org/10.1182/blood-2016-05-714493
Published: 2017
Includes: Supplemental data
Journal Articles

Genetic Alterations Predict Outcomes in Patients with Myelodysplastic Syndrome Receiving Allogeneic Hematopoietic Stem Cell Transplantation

R. Coleman Lindsley, MD PhD, Wael Saber, MD MS, Brenton G. Mar, MD PhD, Robert A Redd, MS, Michael D Haagenson, MS, Peter V Grauman, BS, Stephen R. Spellman, MBS, Stephanie J. Lee, MD, Tao Wang, PhD, Michael R. Verneris, MD, Katharine C. Hsu, MD PhD, Katharina Fleischhauer, MD, Corey S. Cutler, MD MPH, Joseph H. Antin, MD, Donna S. Neuberg, ScD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2016) 128 (22): 69.
https://doi.org/10.1182/blood.V128.22.69.69
Published: 2016
Journal Articles

Clonal Hematopoiesis Associated with Adverse Outcomes Following Autologous Stem Cell Transplantation for Non-Hodgkin Lymphoma

Christopher J. Gibson, MD, R. Coleman Lindsley, MD PhD, Vatche Tchekmedyian, MD, Jiantao Shi, PhD, Brenton G. Mar, MD PhD, Siddhartha Jaiswal, MD PhD, Alysia Bosworth, Liton F. Francisco, BS, Jianbo He, MD, Elizabeth A. Morgan, MD, Ann S. LaCasce, MD, John Koreth, MD, Vincent T. Ho, MD, Jerome Ritz, MD, Sarah Nikiforow, MD PhD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Stephen J. Forman, MD, Franziska Michor, PhD, Donna S. Neuberg, ScD, Smita Bhatia, MD MPH, Ravi Bhatia, MD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2016) 128 (22): 986.
https://doi.org/10.1182/blood.V128.22.986.986
Published: 2016
Journal Articles

SETD2 Heterozygous Loss in Leukemia Leads to Chemotherapy Resistance through Attenuation of the DNA Damage Response

Brenton G. Mar, MDPhD, Josephine Kahn, MD MSc, Rebecca L Zon, BA, Peter V Grauman, BS, Kevin Boettger, BS, Scott Haihua Chu, PhD, Scott A. Armstrong, MD PhD, Benjamin L. Ebert, MD
Journal: Blood
Blood (2015) 126 (23): 2626.
https://doi.org/10.1182/blood.V126.23.2626.2626
Published: 2015
Journal Articles

Acute myeloid leukemia ontogeny is defined by distinct somatic mutations

R. Coleman Lindsley, Brenton G. Mar, Emanuele Mazzola, Peter V. Grauman, Sarah Shareef, Steven L. Allen, Arnaud Pigneux, Meir Wetzler, Robert K. Stuart, Harry P. Erba, Lloyd E. Damon, Bayard L. Powell, Neal Lindeman, David P. Steensma, Martha Wadleigh, Daniel J. DeAngelo, Donna Neuberg, Richard M. Stone, Benjamin L. Ebert
Journal: Blood
Blood (2015) 125 (9): 1367–1376.
https://doi.org/10.1182/blood-2014-11-610543
Published: 2015
Includes: Supplemental data
Journal Articles

Clonal Hematopoiesis with Somatic Mutations Is a Common, Age-Related Condition Associated with Adverse Outcomes

Siddhartha Jaiswal, MDPhD, Pierre Fontanillas, Jason Flannick, Alisa Manning, Peter Grauman, Brenton G. Mar, MDPhD, R. Coleman Lindsley, MDPhD, Craig Mermel, Noel Burtt, Alejandro Chavez, John M. Higgins, MD, Vladislav Moltchanov, Leena Kinnunen, Heikki Koistinen, Claes Ladenvall, Gad Getz, PhD, Adolfo Correa, Stacey Gabriel, PhD, Sekar Kathiresan, Heather Stringham, Michael Boehnke on behalf of GoT2D, Brian Henderson on behalf of SIGMA T2D, Mark McCarthy on behalf of T2D-GENES, Jaako Tuomilehto, Christopher A. Haiman, Sc.D., Leif Groop, Gil Atzmon, James Wilson, Donna S. Neuberg, ScD, David Altshuler, Benjamin L Ebert, MD PhD
Journal: Blood
Blood (2014) 124 (21): 840.
https://doi.org/10.1182/blood.V124.21.840.840
Published: 2014
Journal Articles

Ontogeny-Specific Patterns of Genetic Alterations in Acute Myeloid Leukemia

R. Coleman Lindsley, MDPhD, Brenton G. Mar, MDPhD, Emanuele Mazzola, PhD, Peter Grauman, Sarah Shareef, Daniel J. DeAngelo, MDPhD, Donna S. Neuberg, ScD, Richard M. Stone, MD, Benjamin L. Ebert, MD DPhil
Journal: Blood
Blood (2014) 124 (21): 18.
https://doi.org/10.1182/blood.V124.21.18.18
Published: 2014
Journal Articles

Knockdown of CCR7 or Its Ligands Causes a Loss of Central Nervous System Involvement in Notch1 Induced T-ALL

Silvia Buonamici, Thomas Trimarchi, Apostolos Klinakis, Linsey Reavie, Brenton G. Mar, Eric Gehrie, Emma L. Kuan, Gwendalyn J. Randolph, Jonathan Bromberg, Iannis Aifantis
Journal: Blood
Blood (2008) 112 (11): 199.
https://doi.org/10.1182/blood.V112.11.199.199
Published: 2008
Journal Articles

Novel transcription factors in human CD34 antigen–positive hematopoietic cells

Ignatius Gomes, Tiffany T. Sharma, Seby Edassery, Noreen Fulton, Brenton G. Mar, Carol A. Westbrook
Journal: Blood
Blood (2002) 100 (1): 107–119.
https://doi.org/10.1182/blood.V100.1.107
Published: 2002