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Vicki Plaks
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Journal Articles

Single-cell immune profiling reveals enhanced immune fitness of endogenous and engineered T cells in patients with high-risk smoldering myeloma compared to Relapsed/Refractory myeloma following bispecific antibodies or CAR-T cell therapies.

Free
Francesco Corrado, Nayda Bidikian, Anna Bosch-Vilaseca, Yoshinobu Konishi, Rosa Toenges, Jean-Baptiste Alberge, Ting Wu, Sophie Magidson, Lorena Pantano, Michelle Aranha, Elizabeth Lightbody, Joseph Flinn, Michael Timonian, David Cordas Dos Santos, Rocio Montes De Oca, Tamar Lengil, Diego Vieyra, Mark Wildgust, Vicki Plaks, Denise De Wiest, Kevin De Braganca, Shonali Midha, Elizabeth O'Donnell, Yuxin Liu, Ashlee Sturtevant, Kenneth Anderson, Nikhil Munshi, Jerome Ritz, Omar Nadeem, Gad Getz, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 921.
https://doi.org/10.1182/blood-2025-921
Published: 2025
Journal Articles

Biomarker correlates of clinical outcomes from a global Phase 1b study of JNJ-90014496, CD20/CD19 bi-specific chimeric antigen receptor (CAR) T-cell therapy for patients with large B-cell lymphoma (LBCL)

Free
Mahipal Suraneni, Da Yin, Dianna Wu, Daksh Thaper, Shajo Kunnath-Velayudhan, Jianmei Wu, Alfredo Perales Puchalt, Melissa Beelen, Julie Larsen, Leen Slaets, Arnob Banerjee, Donne Bennett Caces, Jacqueline Bussolari, Luke Mountjoy, Joanna Rhodes, Jacob Christensen, Martin Hutchings, Matthew Ku, Krish Patel, Vicki Plaks
Journal: Blood
Blood (2025) 146 (Supplement 1): 568.
https://doi.org/10.1182/blood-2025-568
Published: 2025
Journal Articles

Earlier use of ciltacabtagene autoleucel (cilta-cel) is associated with better immune fitness and stronger immune effects as shown by correlative analysis of peripheral blood and the bone marrow tumor microenvironment (TME) from the CARTITUDE-4 study

Free
Samir Parekh, Katherine Li, Niels W.C.J. Van De Donk, Yi Lin, Thomas Martin, Siyu Han, Rocio Montes De Oca, Mahipal Suraneni, Michael Gormley, Brendan Hodkinson, Jinzhou Yuan, Feng Wang, Ashwini Kumar, Da Yin, Denis Smirnov, Jaymala Patel, Nikoletta Lendvai, Deepu Madduri, Jieqing Zhu, Mythili Koneru, Nitin Patel, Dong Geng, Vicki Plaks, Simon Harrison
Journal: Blood
Blood (2025) 146 (Supplement 1): 92.
https://doi.org/10.1182/blood-2025-92
Published: 2025
Journal Articles

Ciltacabtagene autoleucel out-of-specification manufacturing outcomes improve with earlier lines of therapy

Free
Robert Bowden, Juan Araque, Gourav Choudhary, Lisa Kallenbach, Victoria Alegria, Octavio Costa, Matthew Perciavalle, James Salmon, Jay Kang, Michael Mondon, Jill Vanak, Daniel Ciccone, Peter Millili, Monica Onorata, Hannelore Van Eeckhoutte, Vicki Plaks, Maximillian Merz
Journal: Blood
Blood (2025) 146 (Supplement 1): 2411.
https://doi.org/10.1182/blood-2025-2411
Published: 2025
Journal Articles

Preclinical Analysis of Ciltacabtagene Autoleucel Combination Strategies with T Cell Bispecifics and Daratumumab to Support Optimization of Clinical Benefit in Myeloma Patients

Free
Douglas Marvel, Gourav Choudhary, Qingxuan Song, Raj Kurupati, Joseph Portale, Mahipal Suraneni, Deeksha Vishwamitra, Jason Brayer, Nicholas Hein, Xuechen Wang, Nikoletta Lendvai, Jordan M. Schecter, J Blake Bartlett, Vicki Plaks
Journal: Blood
Blood (2024) 144 (Supplement 1): 7167.
https://doi.org/10.1182/blood-2024-211334
Published: 2024
Journal Articles

Combination of Ibrutinib with CD19 Chimeric Antigen Receptor (CAR) T Cells Suggests Greater Contribution to CAR T-Cell Efficacy Than Other Approved BTK Inhibitors in the Preclinical Setting

Free
Vicki Plaks, Vidusha Cyril, Peter A Riedell, Qianqian Zhao, Jason Hall, Joel Tan, Diala Harb, Matthew S Davids
Journal: Blood
Blood (2023) 142 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2023-181805
Published: 2023
Journal Articles

CD19 target evasion as a mechanism of relapse in large B-cell lymphoma treated with axicabtagene ciloleucel

Free
Clinical Trials & Observations Brief Report
Vicki Plaks, John M. Rossi, Justin Chou, Linghua Wang, Soumya Poddar, Guangchun Han, Zixing Wang, Shao-Qing Kuang, Fuliang Chu, Richard E. Davis, Francisco Vega, Zahid Bashir, Caron A. Jacobson, Frederick L. Locke, Patrick M. Reagan, Scott J. Rodig, Lazaros J. Lekakis, Ian W. Flinn, David B. Miklos, Adrian Bot, Sattva S. Neelapu
Journal: Blood
Blood (2021) 138 (12): 1081–1085.
https://doi.org/10.1182/blood.2021010930
Published: 2021
Includes: Supplemental data
Journal Articles

Retreatment With Axicabtagene Ciloleucel (Axi-Cel) in Patients With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma in ZUMA-5

Free
Julio C. Chavez, MD, Caron A. Jacobson, MD, Alison R. Sehgal, MD, Sattva S. Neelapu, MD, David G. Maloney, MD PhD, Gilles Salles, MD PhD, Basem M. William, MDMRCP, Yin Yang, MS, Lovely Goyal, PhD, Justin Chou, PhD, Vicki Plaks, LLB, PhD, Mauro P. Avanzi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-135871
Published: 2020
Journal Articles

Primary Analysis of Zuma-5: A Phase 2 Study of Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory (R/R) Indolent Non-Hodgkin Lymphoma (iNHL)

Free
Caron Jacobson, MD MMSc, Julio C. Chavez, MD, Alison R. Sehgal, MD, Basem M. William, MDMRCP, Javier Munoz, MD, Gilles Salles, MDPhD, Pashna N. Munshi, MD, Carla Casulo, MD, David Maloney, MD PhD, Sven de Vos, MD PhD, Ran Reshef, MD, Lori A. Leslie, MD, Ibrahim Yakoub-Agha, Olalekan O. Oluwole, MBBS, MPH, Henry C.H. Fung, MD, Joseph D. Rosenblatt, MD, John M. Rossi, MS, Lovely Goyal, PhD, Vicki Plaks, LLB, PhD, Yin Yang, MS, Jennifer Lee, BS, Wayne Godfrey, MD, Remus Vezan, MD PhD, Mauro P. Avanzi, MD PhD, Sattva S. Neelapu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-136834
Published: 2020
Journal Articles

CD19-Loss with Preservation of Other B Cell Lineage Features in Patients with Large B Cell Lymphoma Who Relapsed Post-Axi-Cel

Free
Sattva S Neelapu, MD, John M. Rossi, MS, Caron A. Jacobson, MD, Frederick L. Locke, MD, David B. Miklos, MD PhD, Patrick M Reagan, MD, Scott J Rodig, MD PhD, Lazaros J. Lekakis, MD, Ian W. Flinn, MD PhD, Lianqing Zheng, PhD, Francesca Milletti, PhD, Edmund Chang, PhD, Allen Xue, PhD, Vicki Plaks, PhD, Jenny J. Kim, MD MS, Adrian Bot, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 203.
https://doi.org/10.1182/blood-2019-126218
Published: 2019
Journal Articles

Earlier Steroid Use with Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Large B Cell Lymphoma

Free
Max Topp, MD, Tom Van Meerten, MD PhD, Roch Houot, MD PhD, Monique C. Minnema, Noel Milpied, MD, Pieternella J. Lugtenburg, MD PhD, Catherine Thieblemont, MD PhD, Martin Wermke, MD, Kevin Song, MD, Irit Avivi, MD, John Kuruvilla, MD, Ulrich Dührsen, Prof, MD PhD, Rachel Chu, PhD, Lianqing Zheng, PhD, Vicki Plaks, PhD, Anne Kerber, MD, Marie Jose' Kersten, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 243.
https://doi.org/10.1182/blood-2019-126081
Published: 2019