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Journal Articles

Serum free light chains in a racially diverse population including African Americans and populations from South Africa

Luca Bertamini, Jean-Baptiste Alberge, David Jungpa Lee, Habib El-Khoury, Sungjae Kim, Grace Fleming, Ciara Suen Marie Murphy, Julia Colchie, Maya I Davis, Jacqueline Perry, Elizabeth D Lightbody, Sabine Allam, Lindokuhle N Goqwana, Vinitha Philip, Natalie Anne Smyth, NA, Dhananjay Sakrikar, Mark C Perkins, Stephen Harding, Derek Troske, Gad Getz, Elizabeth W Karlson, Nikhil C. Munshi, Kenneth C. Anderson, Lorenzo Trippa, Catherine R Marinac, Wenlong Carl Chen, Maureen Joffe, Irene M Ghobrial
Journal: Blood
Blood blood.2024026078.
https://doi.org/10.1182/blood.2024026078
Published: 2024
Includes: Supplemental data
Journal Articles

Deep Learning Unveils Characteristics of Immune B Cell Aging in >17,000 Samples and Identifies Changes in the Immunoglobulin Repertoire Distribution and the Development of Monoclonal Gammopathy

Floris Chabrun, Jean-Baptiste Alberge, Sabine Allam, Jacqueline F Perry, Habib El-Khoury, David J Lee, Michael Timonian, Luca Bertamini, Hadley Barr, Grace Fleming, Joseph Casey Flinn, Ciara Murphy, Sofia Wallin, Hiba Hussain, Elizabeth D. Lightbody, Sungjae Kim, Mark C Perkins, Stephen J. Harding, Dhananjay Sakrikar, Romanos Sklavenitis Pistofidis, Kenneth C. Anderson, Omar Nadeem, Elizabeth K. O'Donnell, Yuxin Liu, Wenlong Chen, Maureen Joffe, Benjamin Levine Ebert, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 4984.
https://doi.org/10.1182/blood-2024-194368
Published: 2024
Journal Articles

Comprehensive Characterization of the Plasma Proteome of Multiple Myeloma and Its Precursor Conditions and Identification of a Proteomic Signature to Improve Risk Prediction of Disease Progression

Elizabeth D. Lightbody, D. R. Mani, Hasmik Keshishian, Namrata Udeshi, Romanos Sklavenitis-Pistofidis, Ankit K. Dutta, Ting Wu, Junko Tsuji, Habib El-Khoury, Hadley Barr, Sarah Nersesian, Nang Kham Su, Cody J. Boehner, Michael P. Agius, Michelle P. Aranha, Laura Hevenor, Katherine Towle, Grace Fleming, Christian Cea-Curry, Daniel Heilpern-Mallory, Erica M. Horowitz, Jacqueline F Perry, Maya Davis, Kelly Walsh, Annie Cowan, John E. Ready, Catherine R. Marinac, Gad Getz, Michael Gillette, Steven A. Carr, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1903.
https://doi.org/10.1182/blood-2024-209286
Published: 2024
Journal Articles

Early Serum Protein Clonal Dynamics Preceding Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma Years before Diagnosis

Sabine Allam, Floris Chabrun, Jean-Baptiste Alberge, Grace Fleming, Sungjae Kim, Yoshinobu Konishi, Habib El-Khoury, Luca Bertamini, Sofia Wallin, Joseph Casey Flinn, Dhananjay Sakrikar, Derek Troske, David Barnidge, Mark C Perkins, Stephen J. Harding, Romanos Sklavenitis-Pistofidis, Paolo Ghia, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3279.
https://doi.org/10.1182/blood-2024-203937
Published: 2024
Journal Articles

Multi-Center Clinical Validation of a Mass Spectrometry Immunoassay for the Diagnosis and Monitoring of Multiple Myeloma and Associated Disorders

Oscar Berlanga, Jane Birtwistle, Syreeta Allen, Gemma Malin, Cristina Simion, Habib El-Khoury, Julia Colchie, Luca Bertamini, Grace Fleming, Erica M. Horowitz, Irene M. Ghobrial, Kaleb B McLendon, John Roback, Andrew S Neish, Sarah K Grewal, Gabriella Lakos
Journal: Blood
Blood (2023) 142 (Supplement 1): 3667.
https://doi.org/10.1182/blood-2023-189050
Published: 2023
Journal Articles

Single-Cell RNA Sequencing of Circulating Tumor Cells in Precursor Myeloma Patients Reveals Mechanisms of Disease Dissemination

Elizabeth D. Lightbody, Romanos Sklavenitis-Pistofidis, Danielle T. Firer, Junko Tsuji, Mike P. Agius, Ankit K. Dutta, Ting Wu, Hadley Barr, Sungjae Kim, Tim Coorens, Jean-Baptiste Alberge, Michelle P. Aranha, Nicholas J Haradhvala, Nang Kham Su, Cody J. Boehner, Kelly Walsh, Mahshid Rahmat, Yoshinobu Konishi, Laura Hevenor, Katherine Towle, Erica M. Horowitz, Jacqueline Perry, Grace Fleming, Habib El-Khoury, Michael Vinyard, Annie Cowan, Daniel Auclair, John E. Ready, Catherine R. Marinac, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 872.
https://doi.org/10.1182/blood-2023-189760
Published: 2023
Journal Articles

High-Throughput Plasma Proteomics to Define the Precursor Multiple Myeloma Proteome and Identify Candidate High-Risk Disease Biomarkers of Progression

Elizabeth D. Lightbody, D. R. Mani, Hasmik Keshishian, Habib El-Khoury, Ankit K. Dutta, Hadley Barr, Namrata Udeshi, Luca Bertamini, Nang Kham Su, Cody J. Boehner, Laura Hevenor, Katherine Towle, Grace Fleming, Christian Cea-Curry, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Annie Cowan, Catherine R. Marinac, Michael Gillette, Steven A. Carr, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 334.
https://doi.org/10.1182/blood-2023-189091
Published: 2023
Journal Articles

Persistence of Monoclonal Gammopathies in Serial Samples from a US Population-Based Screening Study

Habib El-Khoury, Luca Bertamini, Jean-Baptiste Alberge, David J. Lee, Ciara Murphy, Grace Fleming, Christian J. Cea-Curry, Maya I. Davis, Jacqueline Perry, Elizabeth D. Lightbody, Dhananjay Sakrikar, Derek Troske, David Barnidge, Mark C. Perkins, Stephen Harding, Gad Getz, Catherine R. Marinac, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 10101–10103.
https://doi.org/10.1182/blood-2022-169380
Published: 2022
Journal Articles

Abnormal Free Light Chains in Individuals with African Ancestry Screened for Monoclonal Gammopathy: Definition of New Reference Range Accounting for Renal Function and Race

Luca Bertamini, Jean-Baptiste Alberge, Habib El-Khoury, David J. Lee, Ciara Murphy, Grace Fleming, Maya I. Davis, Jacqueline Perry, Christian J. Cea-Curry, Audrey Pentz, Thulisile Hlubi, Natalie Smyth, D.J. Sakrikar, Mark C. Perkins, Stephen Harding, Derek Troske, Gad Getz, Timothy R. Rebbeck, Maureen Joffe, Catherine R. Marinac, Nelson Leung, Carl Wenlong Chen, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 10005–10006.
https://doi.org/10.1182/blood-2022-164436
Published: 2022