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Journal Articles

Serum free light chains in a racially diverse population including African Americans and populations from South Africa

Luca Bertamini, Jean-Baptiste Alberge, David Jungpa Lee, Habib El-Khoury, Sungjae Kim, Grace Fleming, Ciara Suen Marie Murphy, Julia Colchie, Maya I Davis, Jacqueline Perry, Elizabeth D Lightbody, Sabine Allam, Lindokuhle N Goqwana, Vinitha Philip, Natalie Anne Smyth, NA, Dhananjay Sakrikar, Mark C Perkins, Stephen Harding, Derek Troske, Gad Getz, Elizabeth W Karlson, Nikhil C. Munshi, Kenneth C. Anderson, Lorenzo Trippa, Catherine R Marinac, Wenlong Carl Chen, Maureen Joffe, Irene M Ghobrial
Journal: Blood
Blood blood.2024026078.
https://doi.org/10.1182/blood.2024026078
Published: 2024
Includes: Supplemental data
Journal Articles

Early Serum Protein Clonal Dynamics Preceding Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma Years before Diagnosis

Sabine Allam, Floris Chabrun, Jean-Baptiste Alberge, Grace Fleming, Sungjae Kim, Yoshinobu Konishi, Habib El-Khoury, Luca Bertamini, Sofia Wallin, Joseph Casey Flinn, Dhananjay Sakrikar, Derek Troske, David Barnidge, Mark C Perkins, Stephen J. Harding, Romanos Sklavenitis-Pistofidis, Paolo Ghia, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3279.
https://doi.org/10.1182/blood-2024-203937
Published: 2024
Journal Articles

Single-Cell Profiling of ~1.7 Million Plasma Cells across >250 Individuals Reveals Transcriptional Signatures of Progression and Clonal Expansion in Multiple Myeloma and Its Precursor Stages

Junko Tsuji, Elizabeth D. Lightbody, Romanos Sklavenitis-Pistofidis, Ting Wu, Michael P. Agius, Danielle T. Firer, Mahshid Rahmat, Hadley Barr, Yoshinobu Konishi, Ankit K. Dutta, Jean-Baptiste Alberge, Nang Kham Su, Cody J. Boehner, Michelle P. Aranha, Laura Hevenor, Katherine Towle, Erica M. Horowitz, Maya Davis, Jacqueline F Perry, Francois Aguet, Ruitong Li, Sungjae Kim, Nicholas J. Haradhvala, Rebecca Boiarsky, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 4637.
https://doi.org/10.1182/blood-2024-206540
Published: 2024
Journal Articles

Deep Learning Unveils Characteristics of Immune B Cell Aging in >17,000 Samples and Identifies Changes in the Immunoglobulin Repertoire Distribution and the Development of Monoclonal Gammopathy

Floris Chabrun, Jean-Baptiste Alberge, Sabine Allam, Jacqueline F Perry, Habib El-Khoury, David J Lee, Michael Timonian, Luca Bertamini, Hadley Barr, Grace Fleming, Joseph Casey Flinn, Ciara Murphy, Sofia Wallin, Hiba Hussain, Elizabeth D. Lightbody, Sungjae Kim, Mark C Perkins, Stephen J. Harding, Dhananjay Sakrikar, Romanos Sklavenitis Pistofidis, Kenneth C. Anderson, Omar Nadeem, Elizabeth K. O'Donnell, Yuxin Liu, Wenlong Chen, Maureen Joffe, Benjamin Levine Ebert, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 4984.
https://doi.org/10.1182/blood-2024-194368
Published: 2024
Journal Articles

Single-Cell RNA Sequencing of Circulating Tumor Cells in Precursor Myeloma Patients Reveals Mechanisms of Disease Dissemination

Elizabeth D. Lightbody, Romanos Sklavenitis-Pistofidis, Danielle T. Firer, Junko Tsuji, Mike P. Agius, Ankit K. Dutta, Ting Wu, Hadley Barr, Sungjae Kim, Tim Coorens, Jean-Baptiste Alberge, Michelle P. Aranha, Nicholas J Haradhvala, Nang Kham Su, Cody J. Boehner, Kelly Walsh, Mahshid Rahmat, Yoshinobu Konishi, Laura Hevenor, Katherine Towle, Erica M. Horowitz, Jacqueline Perry, Grace Fleming, Habib El-Khoury, Michael Vinyard, Annie Cowan, Daniel Auclair, John E. Ready, Catherine R. Marinac, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 872.
https://doi.org/10.1182/blood-2023-189760
Published: 2023