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Journal Articles

High-Throughput Identification of Graft-Vs-Leukemia TCRs in AML Patient Samples after Allogeneic Stem Cell Transplantation

Noah J Tubo, Duncheng Wang, Qiuming He, Yibin Chen, Ho Ngai, Yanqing Huang, Celine Kerros, Xizeng Mao, Shoudan Liang, Sachet Shukla, Arnau Peris Cuesta, Pavan Bachireddy, Julio Alcantara Montiel, Gheath Alatrash, Priya Koppikar, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 7168.
https://doi.org/10.1182/blood-2023-190330
Published: 2023
Journal Articles

Phase I Study of the T-Cell Receptor-like Antibody, Hu8F4 in Patients with Relapsed and Refractory Myeloid Malignancies

Tapan M. Kadia, Hagop Kantarjian, Gheath Alatrash, Anna Sergeeva, Hong He, Lisa St. John, Priya Koppikar, Celine Kerros, Karen Clise-Dwyer, Kathryn Ruissard, Abhishek Maiti, Courtney D. DiNardo, Elias Jabbour, Srdan Verstovsek, Naveen Pemmaraju, Nitin Jain, Ghayas C. Issa, Guillermo Garcia-Manero, Guillermo Montalban-Bravo, Aditi Shastri, Daniel R. Couriel, Maria Rhona Pinsoy, Sapna Parshottham, Richard E. Champlin, Jorge Cortes, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 1545.
https://doi.org/10.1182/blood-2023-189966
Published: 2023
Journal Articles

A Public Neoantigen Produced By the SF3B1 K700E Mutation Is a Bona Fide T Cell Target in AML/MDS

Noah J Tubo, Duncheng Wang, Qiuming He, Yibin Chen, Ho Ngai, Yanqing Huang, Celine Kerros, Xizeng Mao, Shoudan Liang, Hong He, Gheath Alatrash, Priya Koppikar, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 6816.
https://doi.org/10.1182/blood-2023-190199
Published: 2023
Journal Articles

CD47 Blockade Enhances Phagocytic Activity of the TCR-Mimic Antibody Hu8F4 Against HLA-A2+ AML

Anna Sergeeva, Hong He, Lisa St. John, Ling Yu, Rong Cai, Kathryn Ruissard, Karen Clise-Dwyer, Rolando Vedia, Dan Li, Qing Ma, Celine Kerros, Mithil Chokshi, Vanshika Jhonsa, Gang Bao, Gheath Alatrash, Jeffrey J. Molldrem
Journal: Blood
Blood (2023) 142 (Supplement 1): 4176.
https://doi.org/10.1182/blood-2023-190099
Published: 2023
Journal Articles

Humanized T Cell Receptor-like Antibody Hu8F4 Reduces Leukemia By Fc-Mediated Mechanism

Anna Sergeeva, Hong He, Lisa St John, Celine Kerros, Ling Yu, Rolando A. Vedia, Valeria Rodriguez Gonzalez, Sijie Lu, Gheath Alatrash, Kathryn Cox, Karen Clise-Dwyer, Shao-Ping Yang, Gregory Lizee, Long Vien, Laura Bover, Qing Ma, Mithil Chokshi, Gang Bao, M. James You, Jeffrey J. Molldrem
Journal: Blood
Blood (2022) 140 (Supplement 1): 9061–9062.
https://doi.org/10.1182/blood-2022-162593
Published: 2022
Journal Articles

Pembrolizumab in Combination with Antigen-Specific Cytotoxic T Lymphocytes Enhances Killing of Acute Myeloid Leukemia

Amber Gibson, Mao Zhang, Pariya Sukhumalchandra, Anne V. Philips, Na Qiao, Alexander A. Perakis, Celine Kerros, Lisa St. John, Karen Clise-Dwyer, Sijie Lu, Qing Ma, Jeffrey J. Molldrem, Gheath Alatrash
Journal: Blood
Blood (2021) 138 (Supplement 1): 2775.
https://doi.org/10.1182/blood-2021-149318
Published: 2021
Journal Articles

Characterization of Changes in the T-Cell Receptor Repertoire in Patients with Acute Myeloid Leukemia with Durable Remission Following Allogeneic Stem Cell Transplant

Ronald M. Paranal, MD, Hagop M. Kantarjian, MD, Alexandre Reuben, PhD, Celine Kerros, PhD, Priya Koppikar, PhD, Latasha Little, BS, Curtis Gumbs, Nicholas J. Short, MD, Jorge E. Cortes, MD, Elias Jabbour, MD, Jeffrey J. Molldrem, P. Andrew Futreal, PhD, Ghayas C. Issa, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5186.
https://doi.org/10.1182/blood-2019-129911
Published: 2019
Journal Articles

Pembrolizumab Enhances the Anti-Leukemia Activity of Antigen Specific Cytotoxic T Lymphocytes

Mao Zhang, MPH, Pariya Sukhumalchandra, BS, Anne V. Philips, PhD, Na Qiao, PhD, Celine Kerros, PhD, Lisa St. John, PhD, Alexander A. Perakis, BS, Karen Clise-Dwyer, PhD, Elizabeth Mittendorf, MD PhD, Naval G. Daver, MD, Jeffrey J. Molldrem, MD, Qing Ma, PhD, Gheath Alatrash, DO, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4542.
https://doi.org/10.1182/blood-2018-99-114864
Published: 2018
Journal Articles

Characterizing the Mechanism of NE and P3 Cross-Presentation in B Cell-Acute Lymphoblastic Leukemia

Selena Carmona, MS, Celine Kerros, PhD, Alexander Perakis, Anne Philip, Pariya Sukhumalchandra, Anna Sergeeva, PhD, Lisa St. John, Mao Zhang, MPH, Na Qiao, Elizabeth Mittendorf, Gheath Alatrash, DO, PhD, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3596.
https://doi.org/10.1182/blood.V130.Suppl_1.3596.3596
Published: 2017
Journal Articles

Cross-Presentation Is a Source of Tumor Antigens for Multiple Myeloma Immunotherapy

Alexander A. Perakis, BA, Haley L. Peters, PhD, Jason Roszik, PhD, Mao Zhang, MPH, Anna Sergeeva, PhD, Celine Kerros, PhD, Pariya Sukhumalchandra, BS, Anne V. Philips, PhD, Maria R. Khouri, Rahul U. Popat, Lisa St. John, PhD, Amjad Talukder, PhD, David H. Hawke, PhD, Greg Lizee, PhD, Elizabeth A. Mittendorf, MD PhD, Jeffrey J. Molldrem, MD, Gheath Alatrash, DO, PhD
Journal: Blood
Blood (2016) 128 (22): 2104.
https://doi.org/10.1182/blood.V128.22.2104.2104
Published: 2016
Journal Articles

Humanized Anti-PR1/HLA-A2 T Cell Receptor-like Monoclonal Antibody, h8F4, Has Multiple Effector Mechanisms

Anna Sergeeva, PhD, Hong He, MD, Kathryn Cox, Lisa St John, PhD, Mei Sang, Celine Kerros, PhD, Qiaochuan Li, PhD MD, Amanda Herrmann, Karen Clise-Dwyer, PhD, Qing Ma, PhD, Gregory Lizee, PhD, Gheath Alatrash, DO, PhD, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2016) 128 (22): 4061.
https://doi.org/10.1182/blood.V128.22.4061.4061
Published: 2016
Journal Articles

PR1 Is Cross-Presented By Multiple Myeloma Cells in Patients and Renders Multiple Myeloma Susceptible to PR1-CTL and Anti-PR1/HLA-A2 Antibody

Gheath Alatrash, DO, PhD, Pariya Sukhumalchandra, BS, Mao Zhang, MPH, Celine Kerros, PhD, Anna Sergeeva, PhD, Amanda Cernosek, BS, Haroon Jakher, BS, Madhushree Zope, Rebecca Patenia, MS, Lisa St John, PhD, Alexander Perakis, BA, Karen Dwyer, PhD, Ken H. Young, MD PhD, Jinsheng Weng, PhD, Sijie Lu, PhD, Elizabeth A. Mittendorf, MD PhD, Larry W Kwak, MD PhD, Qing Ma, PhD, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2014) 124 (21): 2133.
https://doi.org/10.1182/blood.V124.21.2133.2133
Published: 2014
Journal Articles

PML and PMLRARα Interact with Fas to Regulate Fas-Mediated Apoptosis In Vivo

Felipe Samaniego, MD, Zuzana Berkova, PhD, Jillian F Wise, BS, Celine Kerros, PhD, David H Hawke, PhD, Judith E. Karp, MD, Hui-Kuan Lin, PhD, Jeffrey J. Molldrem, MD, Rong-Hua Tao, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2451.
https://doi.org/10.1182/blood.V118.21.2451.2451
Published: 2011