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Journal Articles

Efficacy and Toxicity of Frontline Ponatinib Plus Blinatumomab for Adult Ph+ ALL Patients of All Ages. Intermediate Analysis of the Gimema ALL2820

Sabina Chiaretti, Matteo Leoncin, Loredana Elia, Stefano Soddu, Alfonso Piciocchi, Mabel Matarazzo, Mariangela Di Trani, Maurizio Martelli, Erika Borlenghi, Marina Parisi, Valentina Mancini, Caterina Alati, Daniele G. Mattei, Maria Paola Martelli, Prassede Salutari, Patrizia Chiusolo, Ernesta Audisio, Mario Luppi, Lara Pochintesta, Crescenza Pasciolla, Bianca Serio, Barbara Scappini, Antonella Cucca, Martina Chiarucci, Massimiliano Bonifacio, Nicola Fracchiolla, Silvia Imbergamo, Lucia Ammirati, Federico Mosna, Patrizia Zappasodi, Sara Mastaglio, Daniela Pietrasanta, Monica Bocchia, Monia Lunghi, Elisabetta Todisco, Paola Fazi, Alessandro Rambaldi, Robin Foà
Journal: Blood
Blood (2024) 144 (Supplement 1): 835.
https://doi.org/10.1182/blood-2024-207892
Published: 2024
Journal Articles

The Prognostic Value for Survival of Self-Reported Fatigue in Patients with Newly Diagnosed Myelodysplastic Syndromes: An International Prospective Observational Study By the Gimema

Fabio Efficace, Wael Al Essa, Uwe Platzbecker, Pasquale Niscola, Giuseppe A Palumbo, Giovanni Caocci, Serena Puglia, Francesco Sparano, Massimo Breccia, Mario Luppi, Reinhard Stauder, Alessandra Ricco, Duska Petranovic, Frederic Baron, Maria Teresa Voso, Chiara Frairia, Isabella Capodanno, Chiara Sarlo, Rosangela Invernizzi, Claudio Fozza, Maribel Doro, Marco Vignetti
Journal: Blood
Blood (2024) 144 (Supplement 1): 404.
https://doi.org/10.1182/blood-2024-204633
Published: 2024
Journal Articles

Measurable Residual Disease Monitoring for Philadelphia Positive Acute Lymphoblastic Leukemia (Ph+ALL) in the Setting of the Gimema ALL2820 Trial

Marco Beldinanzi, Vittorio Bellomarino, Deborah Cardinali, Irene Della Starza, Mabel Matarazzo, Mariangela Di Trani, Matteo Leoncin, Clara Minotti, Lara Pochintesta, Erika Borlenghi, Caterina Alati, Simona Sica, Valentina Mancini, Barbara Scappini, Bianca Serio, Marina Parisi, Lucia Ammirati, Antonella Cucca, Federico Lussana, Ernesta Audisio, Federico Mosna, Patrizia Zappasodi, Monica Bocchia, Silvia Imbergamo, Mario Luppi, Valeria Cardinali, Crescenza Pasciolla, Claudio Romani, Albana Lico, Benedetta Cambò, Massimiliano Bonifacio, Monica Messina, Daniele G. Mattei, Sara Mastaglio, Lara Aprile, Monia Lunghi, Anna Guarini, Robin Foà, Sabina Chiaretti
Journal: Blood
Blood (2024) 144 (Supplement 1): 2836.
https://doi.org/10.1182/blood-2024-210731
Published: 2024
Journal Articles

Decitabine in older patients with AML: quality of life results of the EORTC-GIMEMA-GMDS-SG randomized phase 3 trial

Clinical Trials & Observations
Fabio Efficace, Michal Kicinski, Corneel Coens, Stefan Suciu, Walter J. F. M. van der Velden, Richard Noppeney, Sylvain Chantepie, Laimonas Griskevicius, Andreas Neubauer, Ernesta Audisio, Mario Luppi, Stephan Fuhrmann, Robin Foà, Martina Crysandt, Gianluca Gaidano, Radovan Vrhovac, Adriano Venditti, Eduardus F. M. Posthuma, Anna Candoni, Frédéric Baron, Olivier Legrand, Andrea Mengarelli, Paola Fazi, Marco Vignetti, Anne Giraut, Pierre W. Wijermans, Gerwin Huls, Michael Lübbert
Journal: Blood
Blood (2024) 144 (5): 541–551.
https://doi.org/10.1182/blood.2023023625
Published: 2024
Includes: Supplemental data
Journal Articles

Chromosome 9p Duplication Promotes T-Cell Exhaustion and Enhances Stem Cell Clonogenic Potential in JAK2-Mutant Myeloproliferative Neoplasms

Ruggiero Norfo, Chiara Carretta, Sandra Parenti, Filippo Badii, Matteo Bertesi, Sebastiano Rontauroli, Lara Tavernari, Elena Genovese, Samantha Sperduti, Elena Enzo, Margherita Mirabile, Francesca Pedrazzi, Chiara Pessina, Ilaria Colugnat, Barbara Mora, Monica Maccaferri, Elena Tenedini, Silvia Martinelli, Elisa Bianchi, Livio Casarini, Leonardo Potenza, Mario Luppi, Enrico Tagliafico, Paola Guglielmelli, Manuela Simoni, Francesco Passamonti, Alessandro Maria Vannucchi, Rossella Manfredini
Journal: Blood
Blood (2023) 142 (Supplement 1): 1780.
https://doi.org/10.1182/blood-2023-182420
Published: 2023
Journal Articles

Comparison between Dasatinib-Blinatumomab Vs Ponatinib-Blinatumomab Chemo-Free Strategy for Newly Diagnosed Ph+ Acute Lymphoblastic Leukemia Patients. Preliminary Results of the Gimema ALLL2820 Trial

Sabina Chiaretti, Matteo Leoncin, Loredana Elia, Alfonso Piciocchi, Mabel Matarazzo, Mariangela Di Trani, Simona Sica, Mario Luppi, Valentina Mancini, Erika Borlenghi, Silvia Imbergamo, Carmine Selleri, Giuseppe Visani, Bruno Martino, Daniele Vallisa, Calogero Vetro, Stefano Soddu, Monica Messina, Paola Fazi, Alessandro Rambaldi, Robin Foà
Journal: Blood
Blood (2023) 142 (Supplement 1): 4249.
https://doi.org/10.1182/blood-2023-189632
Published: 2023
Journal Articles

Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Aged ≥60 Years Treated with a 10-Day Decitabine Schedule Versus Intensive Chemotherapy in the AML21 Study (NCT02172872)

Adriano Venditti, Michal Kicinski, Ernesta Audisio, Mario Luppi, Gianluca Gaidano, Robin Foà, Anna Candoni, Andrea Mengarelli, Attilio Olivieri, Annalisa Imovilli, Maurizio Musso, Paolo De Fabritiis, Eliana Zuffa, Nicola Cascavilla, Agostino Tafuri, Maria Ilaria Del Principe, Stefan Suciu, Anne Giraut, Stéphanie Antunes, Pierre W. Wijermans, Michael Lübbert, Geert A. Huls, Marco Vignetti, Francesco Buccisano
Journal: Blood
Blood (2023) 142 (Supplement 1): 2948.
https://doi.org/10.1182/blood-2023-184851
Published: 2023
Journal Articles

The Unique BCR Inhibiting Properties of BMS-986205 in Chronic Lymphocytic Cells

Claudio Giacinto Atene, Stefania Fiorcari, Nicolò Mesini, Rossana Maffei, Silvia Martinelli, Flora Pilato, Monica Maccaferri, Leonardo Potenza, Mario Luppi, Roberto Marasca
Journal: Blood
Blood (2023) 142 (Supplement 1): 6516.
https://doi.org/10.1182/blood-2023-189127
Published: 2023
Journal Articles

Health-Related Quality of Life and Symptom Burden Profile of Patients with Pre-Fibrotic and Overt Myelofibrosis: A Preliminary Report from the Gimema-Prophecy Observational Study

Giovanni Caocci, Francesca Palandri, Giuseppe Gaetano Loscocco, Alessia Tieghi, Andrea Patriarca, Alessandra Iurlo, Elisabetta Abruzzese, Elena Rossi, Thomas Baldi, Carmen Fava, Eloise Beggiato, Simona Tomasetti, Monia Marchetti, Daniele Vanni, Claudio Fozza, Mario Luppi, Giorgio La Nasa, Paola Fazi, Marco Vignetti, Alessandro Maria Vannucchi, Fabio Efficace
Journal: Blood
Blood (2023) 142 (Supplement 1): 2441.
https://doi.org/10.1182/blood-2023-186429
Published: 2023
Journal Articles

Patients' Perception of Usability and Utility of a Digital Health Tool for Electronic Patient-Reported Outcomes Monitoring in Real-Life Hematology Practice: Evidence from the Gimema-Alliance Platform

Fabio Efficace, Mario Luppi, Leonardo Potenza, Francesco Sparano, Giovanni Caocci, Francesca Fazio, Massimo Breccia, Maria Teresa Petrucci, Andrea Patriarca, Thomas Baldi, Michelina Santopietro, Roberta Battistini, Agostino Tafuri, Gloria Margiotta Casaluci, Elisabetta Colaci, Davide Giusti, Valeria Pioli, Paolo De Fabritiis, Nicolina Rita Ardu, Pasquale Niscola, Olga Mulas, Claudio Fozza, Sergio Siragusa, Salvatrice Mancuso, Paola Boggione, Lorenzo De Paoli, Anna Paola Leporace, Maria Paola Bianchi, Ida Carmosino, Claudio Cartoni, Alice Di Rocco, Isabella Capodanno, Massimo Pini, Alessandra Romano, Paola Fazi, Marco Vignetti
Journal: Blood
Blood (2023) 142 (Supplement 1): 3714.
https://doi.org/10.1182/blood-2023-180574
Published: 2023
Journal Articles

10-Day Decitabine Versus Intensive Chemotherapy Followed By Transplantation in Fit AML Patients Aged ≥60 Years: Health-Related Quality of Life Outcomes of the Randomized Phase III Trial AML21 of the EORTC Leukemia Group, Gimema, Celg, and Gmds-SG

Fabio Efficace, Gerwin A. Huls, Michal Kicinski, Walter JFM Van Der Velden, Richard Noppeney, Sylvain Chantepie, Laimonas Griskevicius, Andreas Neubauer, Ernesta Audisio, Mario Luppi, Stephan Fuhrmann, Robin Foà, Martina Crysandt, Gianluca Gaidano, Radovan Vrhovac, Adriano Venditti, Eduardus F.M. Posthuma, Anna Candoni, Frederic Baron, Olivier Legrand, Andrea Mengarelli, Marco Vignetti, Anne Giraut, Corneel Coens, Stefan Suciu, P.W. Wijermans, Michael Luebbert
Journal: Blood
Blood (2022) 140 (Supplement 1): 1281–1283.
https://doi.org/10.1182/blood-2022-166544
Published: 2022
Journal Articles

Training and Validation Cohorts for Predicting the Impact of High Molecular Risk Mutations after Allogeneic Stem Cell Transplantation in Myelofibrosis

Maria Chiara Finazzi, Alessia Civini, Chiara Pavoni, Anna Grassi, Maria Caterina Mico', Alessandra Algarotti, Marta Bellini, Francesca Patriarca, Paola Guglielmelli, Mario Luppi, Elisa Rumi, Nicola Polverelli, Giuseppe Messina, Stefania Bregante, Giuseppe Milone, Annalisa Imovilli, Benedetto Bruno, Maurizio Musso, Stella Santarone, Massimo Pini, Martina Pennisi, Orietta Spinelli, Francesca Bonifazi, Alessandro Rambaldi, Silvia Salmoiraghi
Journal: Blood
Blood (2022) 140 (Supplement 1): 10622–10623.
https://doi.org/10.1182/blood-2022-162298
Published: 2022
Journal Articles

Peripheral Blood Cytotoxic T Cells from Myelofibrosis Patients Show Early Exhausted Features Targetable By CTLA-4 Inhibition

Lara Tavernari, Sebastiano Rontauroli, Monica Maccaferri, Barbara Mora, Elia Venturelli, Elisa Bianchi, Sandra Parenti, Elena Genovese, Paola Guglielmelli, Chiara Carretta, Margherita Mirabile, Stefano Sartini, Corrado Colasante, Leonardo Potenza, Francesco Passamonti, Enrico Tagliafico, Mario Luppi, Alessandro M. Vannucchi, Rossella Manfredini
Journal: Blood
Blood (2022) 140 (Supplement 1): 9600–9601.
https://doi.org/10.1182/blood-2022-167161
Published: 2022
Journal Articles

Health-Related Quality of Life of Patients with Philadelphia-Negative Myeloproliferative Neoplasms Compared with the General Population: A Preliminary Report from the Gimema Prophecy Study

Giovanni Caocci, Francesca Palandri, Giuseppe Gaetano Loscocco, Alfonso Piciocchi, Alessandra Iurlo, Alessia Tieghi, Andrea Patriarca, Elisabetta Abruzzese, Simona Tomassetti, Monia Marchetti, Daniele Vanni, Mario Luppi, Fabrizio Pane, Massimo Breccia, Sergio Siragusa, Elena Maria Elli, Alessandra Ricco, Claudio Fozza, Maria Teresa Corsetti, Carmen Fava, Camilla Mazzoni, Paola Fazi, Giorgio La Nasa, Marco Vignetti, Alessandro M. Vannucchi, Fabio Efficace
Journal: Blood
Blood (2022) 140 (Supplement 1): 8119–8121.
https://doi.org/10.1182/blood-2022-166039
Published: 2022
Journal Articles

Clinical Utility and Physician Perceptions of a Digital Platform for Electronic Patient-Reported Outcomes Monitoring in Patients with Hematologic Malignancies in Real-World Practice

Fabio Efficace, Massimo Breccia, Giovanni Caocci, Leonardo Potenza, Ida Carmosino, Francesca Fazio, Maria Teresa Petrucci, Isabella Capodanno, Francesco Cottone, Alice Di Rocco, Caterina Patti, Valeria Pioli, Elisabetta Colaci, Davide Giusti, Elisabetta Lugli, Luigi Rigacci, Michelina Santopietro, Fulvia Fanelli, Agostino Tafuri, Maria Paola Bianchi, Claudio Cartoni, Giusy Antolino, Esmeralda Conte, Edoardo La Sala, Massimo Pini, Claudio Fozza, Sergio Siragusa, Marco Santoro, Salvatrice Mancuso, Paolo De Fabritiis, Nicolina Rita Ardu, Pasquale Niscola, Andrea Patriarca, Ombretta Annibali, Mario Luppi, Paola Fazi, Marco Vignetti
Journal: Blood
Blood (2021) 138 (Supplement 1): 4017.
https://doi.org/10.1182/blood-2021-146508
Published: 2021
Journal Articles

Overall Survival Improvement Following ALLO-SCT in Patients Older THAN 60 YEARS: A Gruppo Italiano Trapianto DI Midollo Osseo (GITMO) Registry Study

Michele Malagola, Nicola Polverelli, Massimo Martino, Vicky Rubini, Maria Teresa Lupo Stanghellini, Francesca Patriarca, Renato Fanin, Benedetto Bruno, Luisa Giaccone, Danilo Giuseppe Faraci, Giovanni Grillo, Stefania Bramanti, Luca Castagna, Paolo Bernasconi, Anna Amelia Colombo, Marco De Gobbi, Paolo Nicoli, Annalisa Natale, Stella Santarone, Elisabetta Terruzzi, Attilio Olivieri, Ilaria Scortechini, Patrizia Chiusolo, Elisabetta Metafuni, Angelo Michele Carella, Emanuela Merla, Marco Casini, Irene M Cavattoni, Mario Arpinati, Chiara Nozzoli, Ilaria Cutini, Patrizio Mazza, Annamaria Mazzone, Simona Bassi, Francesco Onida, Giorgia Saporiti, Filippo Antonio Canale, Adriana Vacca, Eugenia Piras, Piero Galieni, Sadia Falcioni, Mario Luppi, Giulia Debbia, Anna Paola Iori, Ursula La Rocca, Vincenzo Pavone, Anna Mele, Cristina Skert, Francesca Carobolante, Paola Carluccio, Carlo Borghero, Francesca Elice, Anna Proia, Fulvia Fanelli, Carmine Selleri, Nicoletta Sacchi, Sonia Mammoliti, Elena Oldani, Fabio Ciceri, Francesca Bonifazi, Domenico Russo
Journal: Blood
Blood (2021) 138 (Supplement 1): 1786.
https://doi.org/10.1182/blood-2021-145970
Published: 2021
Journal Articles

INO-CD22: A Multi-Center, Real-Life Study on Inotuzumab-Ozogamicin Safety and Effectiveness in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Cristina Papayannidis, Patrizia Zappasodi, Nicola S Fracchiolla, Francesco Di Raimondo, Daniele Giovanni Mattei, Francesco Lanza, Endri Mauro, Maria Ilaria Del Principe, Erika Borlenghi, Monica Fumagalli, Elisabetta Todisco, Simona Sica, Nicola Di Renzo, Paolo De Fabritiis, Paolo Corradini, Daniele Vallisa, Fara Petruzziello, Mario Luppi, Fabrizio Pane, Felicetto Ferrara, Francesco Passamonti, Antonino Mulè, Chiara Zingaretti, Giovanni Marconi, Irene Valli, Elisabetta Petracci, Alberto Clemente, Giuseppe Nicola Saglio, Fabio Ciceri, Giovanni Martinelli
Journal: Blood
Blood (2021) 138 (Supplement 1): 4391.
https://doi.org/10.1182/blood-2021-149157
Published: 2021
Journal Articles

Results of the 6-Year Follow-up of the Gimema AML1310 Trial: A Risk-Adapted, MRD-Directed Therapy for Young Adults with Newly Diagnosed Acute Myeloid Leukemia

Adriano Venditti, Alfonso Piciocchi, Raffaele Palmieri, Valentina Arena, Anna Candoni, Valeria Calafiore, Lorella MA Melillo, Roberto Cairoli, Paolo De Fabritiis, Gabriella Storti, Prassede Salutari, Francesco Lanza, Giovanni Martinelli, Mario Luppi, Saveria Capria, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Elisa Buzzatti, Maria Teresa Voso, Tiziana Ottone, Maria irno Consalvo, Paola Fazi, Marco Vignetti, William Arcese, Sergio Amadori, Francesco Buccisano
Journal: Blood
Blood (2021) 138 (Supplement 1): 2359.
https://doi.org/10.1182/blood-2021-147200
Published: 2021
Journal Articles

Indoleamine 2,3-Dioxygenase Mediates Survival of Chronic Lymphocytic Leukemia B Cells through Aryl Hydrocarbon Receptor By Inducing Mcl1

Claudio Giacinto Atene, Rossana Maffei, Stefania Fiorcari, Silvia Martinelli, Patrizia Zucchini, Monica Maccaferri, Giulia Debbia, Leonardo Potenza, Mario Luppi, Roberto Marasca
Journal: Blood
Blood (2020) 136 (Supplement 1): 19.
https://doi.org/10.1182/blood-2020-142345
Published: 2020
Journal Articles

Validation of ELN2017 Risk Stratification in a Post-Hoc Analysis of the Prospective Biomarker-Based Gimema AML1310 Protocol

Raffaele Palmieri, MD, Francesco Buccisano, MD, Alfonso Piciocchi, MS, Valentina Arena, MS, Anna Candoni, Lorella MA Melillo, MD, Valeria Calafiore, Roberto Cairoli, MD, Paolo De Fabritiis, MD, Gabriella Storti, Prassede Salutari, MD, Francesco Lanza, MD, Giovanni Martinelli, MD, Mario Luppi, Saveria Capria, MD, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Maria Teresa Voso, MD, Tiziana Ottone, Serena Lavorgna, Paola Fazi, MD, Marco Vignetti, MD, William Arcese, MD PhD, Adriano Venditti, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-139773
Published: 2020