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Journal Articles

Chromosome 9p Duplication Promotes T-Cell Exhaustion and Enhances Stem Cell Clonogenic Potential in JAK2-Mutant Myeloproliferative Neoplasms

Blood (2023) 142 (Supplement 1): 1780.

https://doi.org/10.1182/blood-2023-182420

Published: 2023

Journal Articles

Peripheral Blood Cytotoxic T Cells from Myelofibrosis Patients Show Early Exhausted Features Targetable By CTLA-4 Inhibition

Lara Tavernari, Sebastiano Rontauroli, Monica Maccaferri, Barbara Mora, Elia Venturelli, Elisa Bianchi, Sandra Parenti, Elena Genovese, Paola Guglielmelli, Chiara Carretta, Margherita Mirabile, Stefano Sartini, Corrado Colasante, Leonardo Potenza, Francesco Passamonti, Enrico Tagliafico, Mario Luppi, Alessandro M. Vannucchi, Rossella Manfredini

Blood (2022) 140 (Supplement 1): 9600–9601.

https://doi.org/10.1182/blood-2022-167161

Published: 2022

Journal Articles

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

Simona Salati, PhD, Elena Genovese, BSc, Zelia Prudente, BSc, PhD, Chiara Carretta, Niccolò Bartalucci, PhD BSc, Valentina Pennucci, PhD, Samantha Ruberti, BSc, PhD, Chiara Rossi, PharmD, Sebastiano Rontauroli, BSc, Carmela Mannarelli, PhD, Roberta Zini, BSc, PhD, Elisa Bianchi, BSc, PhD, Paola Guglielmelli, MD PhD, Enrico Tagliafico, MDPhD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhD

Blood (2018) 132 (Supplement 1): 4332.

https://doi.org/10.1182/blood-2018-99-112550

Published: 2018

Journal Articles

The Role of the Axis TGF-β1/Mir-382-5p/SOD2 in the Induction of Oxidative Stress in CD34+ Hematopoietic Stem/Progenitor Cells from Primary Myelofibrosis

Chiara Rossi, PharmD, Roberta Zini, BSc, PhD, Samantha Ruberti, BSc, PhD, Sebastiano Rontauroli, BSc, Zelia Prudente, BSc, PhD, Greta Barbieri, BSc, Elisa Bianchi, BSc, PhD, Simona Salati, BSc, PhD, Elena Genovese, BSc, Carmela Mannarelli, MSc, PhD, Paola Guglielmelli, MD PhD, Enrico Tagliafico, MDPhD, Vittorio Rosti, MD, Giovanni Barosi, MD, Alessandro M. Vannucchi, Rossella Manfredini, BSc, PhD

Blood (2017) 130 (Supplement 1): 1655.

https://doi.org/10.1182/blood.V130.Suppl_1.1655.1655

Published: 2017

Journal Articles

MiR-494-3p Overexpression Leads to SOCS6 Downregulation and Supports Megakaryocytopoiesis in Primary Myelofibrosis CD34+ Hematopoietic Stem/Progenitor Cells

Sebastiano Rontauroli, BSc, Ruggiero Norfo, PhD, Valentina Pennucci, PhD, Roberta Zini, PhD, Samantha Ruberti, BSc, Elisa Bianchi, PhD, Simona Salati, PhD, Zelia Prudente, PhD, Chiara Rossi, BSc, Vittorio Rosti, Paola Guglielmelli, MD PhD, Giovanni Barosi, Alessandro M. Vannucchi, MD, Enrico Tagliafico, MD PhD, Rossella Manfredini, PhDBSc

Blood (2016) 128 (22): 4272.

https://doi.org/10.1182/blood.V128.22.4272.4272

Published: 2016

Journal Articles

MAF Induces Inflammatory Mediators Involved in the Pathogenesis of Primary Myelofibrosis

Samantha Ruberti, BSc, Elisa Bianchi, PhD, Tiziana Fanelli, MSc, Sebastiano Rontauroli, BSc, Valentina Pennucci, PhD, Giuditta Corbizzi Fattori, BSc, Carmela Mannarelli, MSc, PhD, Ruggiero Norfo, PhD, Chiara Rossi, BSc, Roberta Zini, PhD, Simona Salati, PhD, Zelia Prudente, PhD, Enrico Tagliafico, MDPhD, Paola Guglielmelli, MD PhD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhDBSc

Blood (2016) 128 (22): 3132.

https://doi.org/10.1182/blood.V128.22.3132.3132

Published: 2016

Journal Articles

Genomic landscape of megakaryopoiesis and platelet function defects

Elisa Bianchi, Ruggiero Norfo, Valentina Pennucci, Roberta Zini, Rossella Manfredini

Blood (2016) 127 (10): 1249–1259.

https://doi.org/10.1182/blood-2015-07-607952

Published: 2016

Journal Articles

Integrative Analysis of Copy Number and Gene Expression Data Suggests Novel Pathogenetic Mechanisms in Primary Myelofibrosis

Blood (2015) 126 (23): 2830.

https://doi.org/10.1182/blood.V126.23.2830.2830

Published: 2015

Journal Articles

C-Myb Restrains Megakaryopoiesis through the Hsa-MiR-486-3p-Driven Down-Regulation of C-Maf

Elisa Bianchi, PhD, Jenny Bulgarelli, PhD, Giorgia Sacchi, BiSci, Samantha Ruberti, BiSci, Ruggiero Norfo, PhD, Sebastiano Rontauroli, BiSci, Valentina Pennucci, PhD, Roberta Zini, PhD, Simona Salati, PhD, Zelia Prudente, BiSci, Sergio Ferrari, MD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhD

Blood (2014) 124 (21): 5124.

https://doi.org/10.1182/blood.V124.21.5124.5124

Published: 2014

Journal Articles

miRNA-mRNA integrative analysis in primary myelofibrosis CD34 + cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

Blood (2014) 124 (13): e21–e32.

https://doi.org/10.1182/blood-2013-12-544197

Published: 2014

Includes: Supplemental data

Journal Articles

Abnormal Expression Of WT1-As, MEG3 and ANRIL Long Non-Coding RNAs In Primary Myelofibrosis and Their Clinical Correlates

Blood (2013) 122 (21): 2845.

https://doi.org/10.1182/blood.V122.21.2845.2845

Published: 2013

Journal Articles

Integrative Analysis Of mRNA/miRNA Expression Profiles Identified JARID2 As a Shared Target Of Deregulated Mirnas In Primary Myelofibrosis

Blood (2013) 122 (21): 1600.

https://doi.org/10.1182/blood.V122.21.1600.1600

Published: 2013

Journal Articles

Targeted Cancer Exome Sequencing Discovers Novel Recurrent Mutations In MPN

Elena Tenedini, PhD, Isabella Bernardis, MSc, Valentina Artusi, MSc, Lucia Artuso, PhD, Enrica Roncaglia, PhD, Paola Guglielmelli, PhD MD, Lisa Pieri, PhD MD, Costanza Bogani, PhD, Flavia Biamonte, BiSci, PhD, Elisa Bianchi, PhD, Alessandro Pancrazzi, BiSci, Carmela Mannarelli, BiSci, Tiziana Fanelli, BiSci, Giada Rotunno, BiSci, Guidantonio Malagoli Tagliazucchi, MSc, Sergio Ferrari, MD, Rossella Manfredini, PhD, Alessandro M Vannucchi, MD, Enrico Tagliafico, MD PhD

Blood (2013) 122 (21): 4099.

https://doi.org/10.1182/blood.V122.21.4099.4099

Published: 2013

Journal Articles

Regulatory Mrna/Microrna Networks in CD34+ Cells From Primary Myelofibrosis.

Blood (2012) 120 (21): 2854.

https://doi.org/10.1182/blood.V120.21.2854.2854

Published: 2012

Journal Articles

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice

Valentina Salvestrini, Roberta Zini, Lara Rossi, Sara Gulinelli, Rossella Manfredini, Elisa Bianchi, Wanda Piacibello, Luisa Caione, Giorgia Migliardi, Maria Rosaria Ricciardi, Agostino Tafuri, Marco Romano, Simona Salati, Francesco Di Virgilio, Sergio Ferrari, Michele Baccarani, Davide Ferrari, Roberto M. Lemoli

Blood (2012) 119 (1): 217–226.

https://doi.org/10.1182/blood-2011-07-370775

Published: 2012

Includes: Supplemental data

Journal Articles

C-Myb Transactivates the Expression of Erythroid Hsa-miR16-2 Gene,

Elisa Bianchi, PhD, Paola Guglielmelli, MD, Lorenzo Tozzi, BiSci, Costanza Bogani, PhD, Simona Salati, PhD, Roberta Zini, PhD, Ruggiero Norfo, PhD, Valentina Pennucci, PhD, Alessandro M. Vannucchi, M.D., Rossella Manfredini, BiSci, PhD

Blood (2011) 118 (21): 3386.

https://doi.org/10.1182/blood.V118.21.3386.3386

Published: 2011

Journal Articles

c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression

Elisa Bianchi, Roberta Zini, Simona Salati, Elena Tenedini, Ruggiero Norfo, Enrico Tagliafico, Rossella Manfredini, Sergio Ferrari

Blood (2010) 116 (22): e99–e110.

https://doi.org/10.1182/blood-2009-08-238311

Published: 2010

Includes: Supplemental data

Journal Articles

Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34 − cell population with intrinsic resistance to imatinib

Roberto M. Lemoli, Valentina Salvestrini, Elisa Bianchi, Francesco Bertolini, Miriam Fogli, Marilina Amabile, Agostino Tafuri, Simona Salati, Roberta Zini, Nicoletta Testoni, Cristina Rabascio, Lara Rossi, Ines Martin-Padura, Fausto Castagnetti, Paola Marighetti, Giovanni Martinelli, Michele Baccarani, Sergio Ferrari, Rossella Manfredini

Blood (2009) 114 (25): 5191–5200.

https://doi.org/10.1182/blood-2008-08-176016

Published: 2009

Includes: Supplemental data

Journal Articles

Deranged MicroRNA 16-2 Expression Contributes to Erythropoiesis in Polycythemia Vera.

Paola Guglielmelli, MD, Lorenzo Tozzi, BSc, Vanessa Ponziani, PhD, Elisa Bianchi, PhD, Ilaria Iacobucci, PhD, Betty Giusti, PhD, Luciana Rossi, PhD, Giovanni Martinelli, MD, Rossella Manfredini, MD, Alberto Bosi, MD, Alessandro M. Vannucchi, MD

Blood (2009) 114 (22): 3896.

https://doi.org/10.1182/blood.V114.22.3896.3896

Published: 2009

Journal Articles

Molecular and Functional Analysis of Stem Cell Compartment of Chronic Myelogenous Leukemia Reveals the Presence of a CD34 − cell Population with Intrinsic Resistance to IMATINIB Treatment

Valentina Salvestrini, Rossella Manfredini, MD, Miriam Fogli, Elisa Bianchi, Simona Salati, PhD, Marilina Amabile, Francesco Bertolini, Agostino Tafuri, Roberta Zini, Nicoletta Testoni, Cristina Rabascio, Lara Rossi, Giovanni Martinelli, Michele Baccarani, MD, Sergio Ferrari, Roberto M Lemoli

Blood (2008) 112 (11): 4221.

https://doi.org/10.1182/blood.V112.11.4221.4221

Published: 2008

NARROW

Chromosome 9p Duplication Promotes T-Cell Exhaustion and Enhances Stem Cell Clonogenic Potential in JAK2-Mutant Myeloproliferative Neoplasms

Peripheral Blood Cytotoxic T Cells from Myelofibrosis Patients Show Early Exhausted Features Targetable By CTLA-4 Inhibition

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

The Role of the Axis TGF-β1/Mir-382-5p/SOD2 in the Induction of Oxidative Stress in CD34+ Hematopoietic Stem/Progenitor Cells from Primary Myelofibrosis

MiR-494-3p Overexpression Leads to SOCS6 Downregulation and Supports Megakaryocytopoiesis in Primary Myelofibrosis CD34+ Hematopoietic Stem/Progenitor Cells

MAF Induces Inflammatory Mediators Involved in the Pathogenesis of Primary Myelofibrosis

Genomic landscape of megakaryopoiesis and platelet function defects

Integrative Analysis of Copy Number and Gene Expression Data Suggests Novel Pathogenetic Mechanisms in Primary Myelofibrosis

C-Myb Restrains Megakaryopoiesis through the Hsa-MiR-486-3p-Driven Down-Regulation of C-Maf

miRNA-mRNA integrative analysis in primary myelofibrosis CD34 + cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

Abnormal Expression Of WT1-As, MEG3 and ANRIL Long Non-Coding RNAs In Primary Myelofibrosis and Their Clinical Correlates

Integrative Analysis Of mRNA/miRNA Expression Profiles Identified JARID2 As a Shared Target Of Deregulated Mirnas In Primary Myelofibrosis

Targeted Cancer Exome Sequencing Discovers Novel Recurrent Mutations In MPN

Regulatory Mrna/Microrna Networks in CD34+ Cells From Primary Myelofibrosis.

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice

C-Myb Transactivates the Expression of Erythroid Hsa-miR16-2 Gene,

c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression

Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34 − cell population with intrinsic resistance to imatinib

Deranged MicroRNA 16-2 Expression Contributes to Erythropoiesis in Polycythemia Vera.

Molecular and Functional Analysis of Stem Cell Compartment of Chronic Myelogenous Leukemia Reveals the Presence of a CD34 − cell Population with Intrinsic Resistance to IMATINIB Treatment

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American Society of Hematology

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American Society of Hematology

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