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Journal Articles

Clinical Implications of Central Nervous System Involvement in Acute Myeloid Leukemia

Giovangiacinto Paterno, Flavia Mallegni, Elisa Buzzatti, Maria Irno Consalvo, Elisa Meddi, Federico Moretti, Lucrezia De Marchi, Kristian Taka, Camilla Page, Massimiliano Marinoni, Luca Maurillo, Carmelo Gurnari, Raffaele Palmieri, Francesco Buccisano, Adriano Venditti, Maria Ilaria Del Principe
Journal: Blood
Blood (2024) 144 (Supplement 1): 4252.
https://doi.org/10.1182/blood-2024-209847
Published: 2024
Journal Articles

The Use of Next Generation Flow in Multiple Myeloma Patients: A Preliminary Real-Life Multicenter MRD Harmonization Experience

Stefania Oliva, Elona Saraci, Valentina Trimarco, Marco Chiarini, Nunziatina Laura Parrinello, Renato Zambello, Iole Cordone, Tania Villanova, Serena Masi, Giovanni Rossi, Sara Marino, Anna Maria Triolo, Aldo Roccaro, Angelo Michele Carella, Francesco Buccisano, Angelo Belotti, Maria Irno Consalvo, Alessandra Romano, Alessia Tonini, Silvio Mercadante, Benedetto Bruno, Carolina Terragna, Elena Zamagni
Journal: Blood
Blood (2023) 142 (Supplement 1): 7161.
https://doi.org/10.1182/blood-2023-186536
Published: 2023
Journal Articles

Results of the 6-Year Follow-up of the Gimema AML1310 Trial: A Risk-Adapted, MRD-Directed Therapy for Young Adults with Newly Diagnosed Acute Myeloid Leukemia

Adriano Venditti, Alfonso Piciocchi, Raffaele Palmieri, Valentina Arena, Anna Candoni, Valeria Calafiore, Lorella MA Melillo, Roberto Cairoli, Paolo De Fabritiis, Gabriella Storti, Prassede Salutari, Francesco Lanza, Giovanni Martinelli, Mario Luppi, Saveria Capria, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Elisa Buzzatti, Maria Teresa Voso, Tiziana Ottone, Maria irno Consalvo, Paola Fazi, Marco Vignetti, William Arcese, Sergio Amadori, Francesco Buccisano
Journal: Blood
Blood (2021) 138 (Supplement 1): 2359.
https://doi.org/10.1182/blood-2021-147200
Published: 2021
Journal Articles

Clinical Relevance of- Limit of Detection (LOD) - Limit of Quantification (LOQ) - Based Flow Cytometry Approach for Measurable Residual Disease (MRD) Assessment in Acute Myeloid Leukemia (AML)

Raffaele Palmieri, MD, Alfonso Piciocchi, Valentina Arena, MS, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Tiziana Ottone, Mariadomenica Divona, Serena Lavorgna, Maria Irno Consalvo, Consuelo Conti, Cristina Attrotto, Daniela Fraboni, Maria Teresa Voso, MD, William Arcese, MD PhD, Adriano Venditti, MD, Francesco Buccisano, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-139557
Published: 2020
Journal Articles

Multiparametric Flow-Cytometry Is a Reliable Tool for Measurable Residual Disease Assessment and Risk-Stratification of FLT3-Mutated AML Patients

Raffaele Palmieri, MD, Luca Maurillo, Alfonso Piciocchi, Maria Ilaria Del Principe, Valentina Arena, Stefano Soddu, Ambra Di Veroli, MD, Giovangiacinto Paterno, Eleonora De Bellis, Raffaella Cerretti, Gottardo De Angelis, Benedetta Mariotti, Tiziana Ottone, Mariadomenica Divona, Serena Lavorgna, Maria Irno Consalvo, Consuelo Conti, Cristina Attrotto, Daniela Fraboni, William Arcese, Maria Teresa Voso, MD, Adriano Venditti, Francesco Buccisano, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5083.
https://doi.org/10.1182/blood-2019-129184
Published: 2019
Journal Articles

Leukemic Stem Cells Persistence Measured By Multiparametric Flow Cytometry Is a Biomarker of Poor Prognosis in Adult Patients with Acute Myeloid Leukemia

Francesco Buccisano, MD, Raffaele Palmieri, MD, Maria Irno Consalvo, Alfonso Piciocchi, Luca Maurillo, Maria Ilaria Del Principe, Valentina Arena, Stefano Soddu, Ambra Di Veroli, MD, Giovangiacinto Paterno, Eleonora De Bellis, Daniela Fraboni, Consuelo Conti, Maria Teresa Voso, MD, William Arcese, Adriano Venditti
Journal: Blood
Blood (2019) 134 (Supplement_1): 2688.
https://doi.org/10.1182/blood-2019-128025
Published: 2019
Journal Articles

Mutational Profile of Leukemic Stem Cells in FLT3 -ITD Mutated AML

Tiziana Ottone, Serena Travaglini, Valentina Alfonso, PhD, Daniela Angelini, PhD, Gisella Guerrera, PhD, Serena Lavorgna, Mariadomenica Divona, Anna Maria Nardozza, Antonio Cristiano, Maria irno Consalvo, PhD, Marco de Bardi, PhD, Benedetta Neri, MD, Francesco Marchesi, Carmelo Gurnari, MD, Giovangiacinto Paterno, Vincenza Martini, MD, Luca Battistini, MD, PhD, Adriano Venditti, Francesco Buccisano, MD, William Arcese, Francesco Lo-Coco, Maria Teresa Voso, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1458.
https://doi.org/10.1182/blood-2019-126040
Published: 2019
Journal Articles

GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia

Clinical Trials & Observations
Adriano Venditti, Alfonso Piciocchi, Anna Candoni, Lorella Melillo, Valeria Calafiore, Roberto Cairoli, Paolo de Fabritiis, Gabriella Storti, Prassede Salutari, Francesco Lanza, Giovanni Martinelli, Mario Luppi, Patrizio Mazza, Maria Paola Martelli, Antonio Cuneo, Francesco Albano, Francesco Fabbiano, Agostino Tafuri, Anna Chierichini, Alessia Tieghi, Nicola Stefano Fracchiolla, Debora Capelli, Robin Foà, Caterina Alati, Edoardo La Sala, Paola Fazi, Marco Vignetti, Luca Maurillo, Francesco Buccisano, Maria Ilaria Del Principe, Maria Irno-Consalvo, Tiziana Ottone, Serena Lavorgna, Maria Teresa Voso, Francesco Lo-Coco, William Arcese, Sergio Amadori
Journal: Blood
Blood (2019) 134 (12): 935–945.
https://doi.org/10.1182/blood.2018886960
Published: 2019
Includes: Supplemental data
Journal Articles

Clinical Significance of Occult Central Nervous System Disease in Adult ACUTE Lymphoblastic Leukemia. a Multicenter,Report from the Campus ALL/Gimema Network

Maria Ilaria Del Principe, MD, Elisa Buzzati, MD, Fabio Forghieri, MD, Federica Lessi, MD, Silvia Imbergamo, MD, Enrico Orciulo, MD, Giovanni Rossi, Nicola Fracchiolla, MD, Silvia Trappolini, MD, Benedetta Neri, MD, Chiara Sarlo, MD, Patrizia Zappasodi, MD, Michelina Dargenio, MD, Mariagiovanna Cefalo, MD, Maria irno Consalvo, PhD, Gottardo De Angelis, MD, Mariarita Sciumè, Irene Della Starza, PhD, Anna Guarini, PhD, Robin Foà, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 658.
https://doi.org/10.1182/blood-2018-99-114177
Published: 2018
Journal Articles

Longitudinal Detection of DNMT3A R882H Transcripts in Patients with Acute Myeloid Leukemia

Tiziana Ottone, PhD, Valentina Alfonso, BS, Licia Iaccarino, BS, Syed Khizer Hasan, PhD, Melissa Mancini, PhD, Mariadomenica Divona, BS, Serena Lavorgna, PhD, Laura Cicconi, Paola Panetta, PhD, Luca Maurillo, MD, PhD, Maria Ilaria Del Principe, Maria irno Consalvo, PhD, Luca Franceschini, MD, PhD, Daniela Angelini, PhD, Luca Battistini, MD, PhD, Gisella Guerrera, PhD, Marco de Bardi, PhD, Emiliano Fabiani, PhD, Giulia Falconi, PhD, William Arcese, MD, Sergio Amadori, MD, Francesco Buccisano, MD, Adriano Venditti, MD, Maria Teresa Voso, MD, Francesco Lo Coco, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3959.
https://doi.org/10.1182/blood.V130.Suppl_1.3959.3959
Published: 2017
Journal Articles

Pattern of Central Nervous System (CNS) Involvement in Adult Acute Myeloid Leukemia (AML) and Its Impact on Outcome

Maria Ilaria Del Principe, MD, Francesco Buccisano, Stefano Soddu, Luca Maurillo, MD, Mariagiovanna Cefalo, Alfonso Piciocchi, Giovangiacinto Paterno, MD, Chiara Sarlo, Gottardo De Angelis, MD, Vittorio Forte, Maria Irno Consalvo, Daniela Fraboni, Eleonora De Bellis, MD, Annagiulia Zizzari, MD, Mariadomenica Divona, Giuseppe Sconocchia, Maria Teresa Voso, MD, Giovanni Del Poeta, MD, Francesco Lo Coco, MD, Sergio Amadori, MD, William Arcese, Adriano Venditti, MD
Journal: Blood
Blood (2016) 128 (22): 2789.
https://doi.org/10.1182/blood.V128.22.2789.2789
Published: 2016
Journal Articles

Cytogenetic and molecular diagnostic characterization combined to postconsolidation minimal residual disease assessment by flow cytometry improves risk stratification in adult acute myeloid leukemia

Clinical Trials & Observations
Francesco Buccisano, Luca Maurillo, Alessandra Spagnoli, Maria Ilaria Del Principe, Daniela Fraboni, Paola Panetta, Tiziana Ottone, Maria Irno Consalvo, Serena Lavorgna, Pietro Bulian, Emanuele Ammatuna, Daniela F. Angelini, Adamo Diamantini, Selenia Campagna, Licia Ottaviani, Chiara Sarlo, Valter Gattei, Giovanni Del Poeta, William Arcese, Sergio Amadori, Francesco Lo Coco, Adriano Venditti
Journal: Blood
Blood (2010) 116 (13): 2295–2303.
https://doi.org/10.1182/blood-2009-12-258178
Published: 2010
Includes: Supplemental data
Journal Articles

A monoclonal antibody against mutated nucleophosmin 1 for the molecular diagnosis of acute myeloid leukemias

Alicja M. Gruszka, Serena Lavorgna, Maria Irno Consalvo, Tiziana Ottone, Chiara Martinelli, Mario Cinquanta, Giuseppe Ossolengo, Giancarlo Pruneri, Francesco Buccisano, Mariadomenica Divona, Michele Cedrone, Emanuele Ammatuna, Adriano Venditti, Ario de Marco, Francesco Lo-Coco, Pier Giuseppe Pelicci
Journal: Blood
Blood (2010) 116 (12): 2096–2102.
https://doi.org/10.1182/blood-2010-01-266908
Published: 2010
Includes: Supplemental data
Journal Articles

The Amount of Spontaneous Apoptosis Is An Independent Strong Disease Progression Indicator in B-Cell Chronic Lymphocytic Leukemia (B-CLL)

Giovanni Del Poeta, Maria Ilaria Del Principe, Francesco Buccisano, Daniela Piccioni, Luca Maurillo, Chiara Sarlo, Maria Irno Consalvo, Pietro Bulian, Antonella Zucchetto, Laura Giannì, Cristina Simotti, Paolo de Fabritiis, Adriano Venditti, Valter Gattei, Sergio Amadori
Journal: Blood
Blood (2009) 114 (22): 1252.
https://doi.org/10.1182/blood.V114.22.1252.1252
Published: 2009
Journal Articles

ZAP-70 Expression Evaluated by Mean Fluorescence Intensity T/B Ratio Is a More Useful Prognosticator Than Percentage of Positive Cells in Chronic Lymphocytic Leukemia (CLL).

Francesca Maria Rossi, Maria Ilaria Del Principe, Davide Rossi, Maria Irno Consalvo, Fabrizio Luciano, Antonella Zucchetto, Pietro Bulian, Riccardo Bomben, Dania Benedetti, Michele Dal-Bo, Massimo Degan, Gianluca Gaidano, Giovanni Del Poeta, Valter Gattei
Journal: Blood
Blood (2009) 114 (22): 1257.
https://doi.org/10.1182/blood.V114.22.1257.1257
Published: 2009
Journal Articles

The Earliest Activation Marker CD69 Is An Independent and Strong Progression Indicator in B-Cell Chronic Lymphocytic Leukemia.

Giovanni Del Poeta, Maria Ilaria Del Principe, Cristina Simotti, Francesco Buccisano, Luca Maurillo, Antonella Zucchetto, Licia Ottaviani, Pietro Bulian, Chiara Sarlo, Maria Irno Consalvo, Adriano Venditti, Paolo de Fabritiis, Valter Gattei, Sergio Amadori
Journal: Blood
Blood (2009) 114 (22): 2359.
https://doi.org/10.1182/blood.V114.22.2359.2359
Published: 2009
Journal Articles

The Amount of Mitochondrial Apoptosis Exerts Prognostic Impact on Normal Karyotype Acute Myeloid Leukemia.

Giovanni Del Poeta, Maria Ilaria Del Principe, Francesco Buccisano, Luca Maurillo, Benedetta Neri, Licia Ottaviani, Fabrizio Luciano, Daniela Piccioni, Maria Irno Consalvo, Emanuele Ammatuna, Antonio Bruno, Paolo de Fabritiis, Valter Gattei, Adriano Venditti, Francesco Lo Coco, Sergio Amadori
Journal: Blood
Blood (2008) 112 (11): 1481.
https://doi.org/10.1182/blood.V112.11.1481.1481
Published: 2008
Journal Articles

Flow-Cytometric Minimal Residual Disease Determination Is a Surrogate Prognosticator in Adult AML Patients Lacking Specific Molecular Signatures.

Francesco Buccisano, MD, Luca Maurillo, MD, Giovanni Del Poeta, MD, Maria Ilaria Del Principe, MD, Daniela Fraboni, PhD, Emanuele Ammatuna, MD, Maria Irno Consalvo, PhD, Paola Panetta, PhD, Licia Ottaviani, MD, Sabrina Faccia, MD, Manuela Rizzo, MD, Massimiliano Postorino, MD, Maria Cantonetti, MD, Francesco Lo Coco, MD, Sergio Amadori, MD, Adriano Venditti, MD
Journal: Blood
Blood (2007) 110 (11): 3498.
https://doi.org/10.1182/blood.V110.11.3498.3498
Published: 2007
Journal Articles

Detection of Minimal Residual Disease by Flow-Cytometry Otimizes Risk Stratification When Combined with Cytogenetics in AML.

Francesco Buccisano, MD, Luca Maurillo, MD, Giovanni Del Poeta, MD, Maria Ilaria Del Principe, MD, Paola Panetta, PhD, Daniela Fraboni, PhD, Maria Irno Consalvo, PhD, Daniela Renzi, MD, Selenia Campagna, MD, Chiara Sarlo, MD, Luca Franceschini, MD, Laura Giannì, MD, Emanuele Ammatuna, MD, Francesco Lo Coco, MD, Sergio Amadori, MD, Adriano Venditti, MD
Journal: Blood
Blood (2007) 110 (11): 4242.
https://doi.org/10.1182/blood.V110.11.4242.4242
Published: 2007
Journal Articles

Optimal Post-Remission Therapy for Flow-Cytometry Minimal Residual Disease Positive Patients with Acute Myeloid Leukemia.

Francesco Buccisano, MD, Luca Maurillo, MD, Valter Gattei, MD, Giovanni Del Poeta, MD, Maria Ilaria Del Principe, MD, Fraboni Fraboni, Phd, Paola Panetta, Phd, Maria Irno Consalvo, Phd, Selenia Campagna, MD, Laura Giannì, MD, Licia Ottaviani, MD, Massimiliano Postorino, MD, Paolo De Fabritiis, MD, William Arcese, MD, Francesco Lo Coco, MD, Sergio Amadori, MD, Adriano Venditti, MD
Journal: Blood
Blood (2006) 108 (11): 610.
https://doi.org/10.1182/blood.V108.11.610.610
Published: 2006