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Michele Dal-Bo
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Journal Articles

KRAS , NRAS and BRAF Mutations Are Highly Enriched in TRI12 Chronic Lymphocytic Leukemia and Are Associated to Shorter Time to First Treatment

Elena Vendramini, PhD, Riccardo Bomben, PhD, Federico Pozzo, PhD, Dania Benedetti, PhD, Maria Francesca Rossi, PhD, Michele Dal Bo, PhD, Gabriele Pozzato, MD, Francesco Zaja, MD, Annalisa Chiarenza, MD PhD, Francesco Di Raimondo, MD, Giovanni Del Poeta, MD, Valter Gattei, MD, Antonella Zucchetto
Journal: Blood
Blood (2018) 132 (Supplement 1): 3113.
https://doi.org/10.1182/blood-2018-99-111864
Published: 2018
Journal Articles

SF3B1 Mutations Associate with Low CD20 Expression in CLL: Another NOTCH1 -Dependent Mechanism?

Federico Pozzo, PhD, Tamara Bittolo, PhD, Erika Tissino, PhD, Filippo Vit, MSc, Elena Vendramini, PhD, Riccardo Bomben, PhD, Antonella Zucchetto, Michele Dal Bo, PhD, Luca Laurenti, MD, Giovanni Francesco D'Arena, MD, Francesco Di Raimondo, MD, Annalisa Chiarenza, MD PhD, Gabriele Pozzato, MD, Francesco Zaja, MD, Giovanni Del Poeta, MD, Valter Gattei, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1838.
https://doi.org/10.1182/blood-2018-99-111894
Published: 2018
Journal Articles

Comprehensive Characterization of NOTCH1 Mutational Status in Chronic Lymphocytic Leukemia: Clinical Relevance of Subclonal Mutations and Mutation Types

Tiziana D'Agaro, Tamara Bittolo, Vanessa Bravin, Antonella Zucchetto, Michele Dal Bo, Francesca Rossi, Federico Pozzo, Annalisa Chiarenza, Giovanni D'Arena, Gabriele Pozzato, Francesco Zaja, Davide Rossi, MD PhD, Francesco Di Raimondo, MD, Gianluca Gaidano, MD PhD, Giovanni Del Poeta, MD, Pietro Bulian, Valter Gattei, Riccardo Bomben
Journal: Blood
Blood (2016) 128 (22): 3195.
https://doi.org/10.1182/blood.V128.22.3195.3195
Published: 2016
Journal Articles

Low Bax/Bcl-2 Ratio and NOTCH1 Mutations Represent Powerful and Synergistic Adverse Prognostic Factors within Trisomy 12 Chronic Lymphocytic Leukemia (CLL)

Giovanni Del Poeta, MD, Maria Ilaria Del Principe, MD, Massimiliano Postorino, Michele Dal Bo, Maria Francesca Rossi, Francesco Buccisano, Luca Maurillo, MD, Davide Rossi, Livio Pupo, Benedetta Mariotti, Adriano Venditti, MD, Paolo de Fabritiis, MD, Maria Cantonetti, Gianluca Gaidano, Francesco Lo Coco, MD, Valter Gattei, Sergio Amadori, MD
Journal: Blood
Blood (2016) 128 (22): 3204.
https://doi.org/10.1182/blood.V128.22.3204.3204
Published: 2016
Journal Articles

Lack of Prognostic Significance of the Conventional and Novel Prognostic Markers in Trisomy 12 Chronic Lymphocytic Leukemia (CLL)

Valter Gattei, Riccardo Bomben, Michele Dal Bo, Antonella Zucchetto, Francesca Rossi, Massimo Degan, Federico Pozzo, Tamara Bittolo, Vanessa Bravin, Tiziana D'Agaro, Claudia Perini, Annalisa Chiarenza, Kari G. Chaffee, MS, Giovanni D'Arena, MD, Francesco Zaja, Gabriele Pozzato, MD, Francesco Di Raimondo, MD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Gianluca Gaidano, MD PhD, Tait D. Shanafelt, MD, Pietro Bulian
Journal: Blood
Blood (2016) 128 (22): 4354.
https://doi.org/10.1182/blood.V128.22.4354.4354
Published: 2016
Journal Articles

The B-Cell Receptor Signaling Inhibitor Molecules CD305 and CD307b Are Markers of Favorable Prognosis in Chronic Lymphocytic Leukemia with Both Mutated and Unmutated IGHV Gene Status

Dania Benedetti, Claudia Perini, Erika Tissino, Michele Dal Bo, Pietro Bulian, Riccardo Bomben, Francesca Rossi, Massimo Degan, Alessandro Poggi, Mahdi Shabani, Fazel Shokri, Francesco Zaja, MD, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, MD, Giovanni Del Poeta, MD, Valter Gattei, Antonella Zucchetto
Journal: Blood
Blood (2016) 128 (22): 4358.
https://doi.org/10.1182/blood.V128.22.4358.4358
Published: 2016
Journal Articles

Mutations at 3' Untranslated Region (3'UTR) of NOTCH1 Are Associated with Low CD20 Expression Levels in Chronic Lymphocytic Leukemia

Tamara Bittolo, Federico Pozzo, Riccardo Bomben, Tiziana D'Agaro, Vanessa Bravin, Pietro Bulian, Francesca Rossi, Antonella Zucchetto, Massimo Degan, Paolo Macor, Giovanni D'Arena, Annalisa Chiarenza, Francesco Zaja, Gabriele Pozzato, Francesco Di Raimondo, MD, Davide Rossi, Gianluca Gaidano, Giovanni Del Poeta, MD, Valter Gattei, Michele Dal Bo
Journal: Blood
Blood (2016) 128 (22): 306.
https://doi.org/10.1182/blood.V128.22.306.306
Published: 2016
Journal Articles

HIF-1α Upregulation in TP53 Disrupted Chronic Lymphocytic Leukemia Cells and Its Potential Role As a Therapeutic Target

Valentina Griggio, Ms, Candida Vitale, MD, Maria Todaro, PhD, Chiara Riganti, MD, Joanna Kopecka, PhD, Michele Dal Bo, Davide Rossi, Gabriele Pozzato, MD, Monia Marchetti, MD PhD, Marina Ruggeri, Paola Omedè, PhD, Luca Laurenti, Giovanni Del Poeta, MD, Francesca Romana Mauro, MD PhD, Valter Gattei, Gianluca Gaidano, MD PhD, Robin Foa, Massimo Massaia, MD, Mario Boccadoro, MD, Marta Coscia, MD PhD
Journal: Blood
Blood (2016) 128 (22): 305.
https://doi.org/10.1182/blood.V128.22.305.305
Published: 2016
Journal Articles

Identification of a Novel Gene Expression Signature in Mantle Cell Lymphoma from the Fondazione Italiana Linfomi (FIL)-MCL-0208 Trial: A Focus on the B Cell Receptor Pathway

Riccardo Bomben, Simone Ferrero, Michele Dal Bo, Tiziana D'Agaro, Alessandro Re, Andrea Evangelista, Angelo Michele Carella, Alberto Zamò, Umberto Vitolo, MD, Paola Omedè, Chiara Rusconi, Luca Arcaini, Luigi Rigacci, Stefano Luminari, MD, Sergio Cortelazzo, Marco Ladetto, Valter Gattei, MD
Journal: Blood
Blood (2015) 126 (23): 701.
https://doi.org/10.1182/blood.V126.23.701.701
Published: 2015
Journal Articles

CD49d Prevails over the Novel Recurrent Mutations As Independent Prognosticator of Overall Survival in Chronic Lymphocytic Leukemia

Michele Dal Bo, Pietro Bulian, Riccardo Bomben, Antonella Zucchetto, Francesca Rossi, Federico Pozzo, Tamara Bittolo, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Hillarj Chivilò, Massimo Degan, Francesco Zaja, MD, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, MDPhD, Giovanni Del Poeta, Pr, MD, Davide Rossi, MD PhD, Gianluca Gaidano, Valter Gattei
Journal: Blood
Blood (2015) 126 (23): 1706.
https://doi.org/10.1182/blood.V126.23.1706.1706
Published: 2015
Journal Articles

Retention of inside-out VLA-4 Integrin Activation upon B-Cell Receptor Triggering in in-Vitro and in-Vivo Ibrutinib Treated Chronic Lymphocytic Leukemia Cells: Clinical Implication

Erika Tissino, Chiara Caldana, Dania Benedetti, Francesca Rossi, Michele Dal Bo, Pietro Bulian, Riccardo Bomben, Francesco Zaja, MD, Annalisa Chiarenza, Tanja Nicole Hartmann, Alexandre Chigaev, Giovanni Del Poeta, Valter Gattei, Antonella Zucchetto
Journal: Blood
Blood (2015) 126 (23): 1708.
https://doi.org/10.1182/blood.V126.23.1708.1708
Published: 2015
Journal Articles

Apoptosis and Proliferation Synergistically Determine Overall Survival in Chronic Lymphocytic Leukemia (CLL)

Giovanni Del Poeta, Michele Dal Bo, Francesco Buccisano, Federico Pozzo, Maria Ilaria Del Principe, MD, Pietro Bulian, Davide Rossi, MD PhD, Adriano Venditti, MD, Paolo de Fabritiis, Gianluca Gaidano, MD PhD, Sergio Amadori, MD, Valter Gattei
Journal: Blood
Blood (2015) 126 (23): 1718.
https://doi.org/10.1182/blood.V126.23.1718.1718
Published: 2015
Journal Articles

The Concomitant High Expression of the B-Cell Receptor Signaling Inhibitor Molecules CD150, CD305, and CD307b Predicts Longer Overall Survival in the Context of Low-Risk Chronic Lymphocytic Leukemia

Antonella Zucchetto, Dania Benedetti, Chiara Caldana, Erika Tissino, Michele Dal Bo, Pietro Bulian, Riccardo Bomben, Francesca Rossi, Francesco Zaja, MD, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, MDPhD, Giovanni Del Poeta, Valter Gattei
Journal: Blood
Blood (2015) 126 (23): 1720.
https://doi.org/10.1182/blood.V126.23.1720.1720
Published: 2015
Journal Articles

The Hypoxia-Inducible Factor-1alpha Is Constitutively Upregulated in TP53 Disrupted CLL Cells: A Potential Target to Overcome Fludarabine Resistance

Valentina Griggio, Ms, Candida Vitale, MD, Chiara Riganti, MD, Joanna Kopecka, PhD, Michele Dal Bo, Davide Rossi, MD PhD, Gabriele Pozzato, MD, Luca Laurenti, MD, Francesco Zallio, MD, Monia Marchetti, MD PhD, Marina Ruggeri, Paola Omedè, Giovanni Del Poeta, Pr, MD, Valter Gattei, MD, Gianluca Gaidano, MD PhD, Mario Boccadoro, MD, Massimo Massaia, MD, Marta Coscia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2925.
https://doi.org/10.1182/blood.V126.23.2925.2925
Published: 2015
Journal Articles

Ibrutinib-naïve chronic lymphocytic leukemia lacks Bruton tyrosine kinase mutations associated with treatment resistance

Rosella Famà, Riccardo Bomben, Silvia Rasi, Michele Dal Bo, Carmela Ciardullo, Sara Monti, Francesca Rossi, Tiziana D’Agaro, Antonella Zucchetto, Valter Gattei, Gianluca Gaidano, Davide Rossi
Journal: Blood
Blood (2014) 124 (25): 3831–3833.
https://doi.org/10.1182/blood-2014-08-592725
Published: 2014
Includes: Supplemental data
Journal Articles

NOTCH1 Mutations Are Associated with High CD49d Expression in Chronic Lymphocytic Leukemia

Antonella Zucchetto, Chiara Caldana, Federico Pozzo, Silvia Rasi, Carmela Ciardullo, Dania Benedetti, Erika Tissino, Francesca Maria Rossi, Riccardo Bomben, Francesco Zaja, MD, Gabriele Pozzato, Francesco Di Raimondo, MD, Giovanni Del Poeta, Michele Dal Bo, Davide Rossi, MD PhD, Gianluca Gaidano, MD PhD, Valter Gattei
Journal: Blood
Blood (2014) 124 (21): 1978.
https://doi.org/10.1182/blood.V124.21.1978.1978
Published: 2014
Journal Articles

NOTCH1 Mutated IGHV Unmutated Chronic Lymphocytic Leukemia Cells Are Characterized By a Constitutive Overexpression of Nucleophosmin-1 and Ribosome-Associated Components

Federico Pozzo, Tamara Bittolo, Erika Tissino, Francesca Maria Rossi, Riccardo Bomben, Antonella Zucchetto, Dania Benedetti, Francesca Arruga, PhD, Branimir Gizdic, Massimo Degan, Pietro Bulian, Giovanni D'Arena, Francesco Di Raimondo, MD, Francesco Zaja, Gabriele Pozzato, Alberto Zamò, MD PhD, Silvia Deaglio, MD PhD, Davide Rossi, Gianluca Gaidano, Giovanni Del Poeta, Michele Dal Bo, Valter Gattei
Journal: Blood
Blood (2014) 124 (21): 3308.
https://doi.org/10.1182/blood.V124.21.3308.3308
Published: 2014
Journal Articles

NOTCH1 Mutations Are Associated with Low CD20 Expression in Chronic Lymphocytic Leukemia: Evidences for a NOTCH1 -Mediated Epigenetic Regulatory Mechanism

Federico Pozzo, Tamara Bittolo, Pietro Bulian, Erika Tissino, Francesca Maria Rossi, Paolo Macor, PhD, Riccardo Bomben, Antonella Zucchetto, Dania Benedetti, Francesca Arruga, PhD, Branimir Gizdic, Massimo Degan, Giovanni D'Arena, Francesco Di Raimondo, MD, Francesco Zaja, Gabriele Pozzato, Silvia Deaglio, MD PhD, Davide Rossi, MD PhD, Gianluca Gaidano, MD, Giovanni Del Poeta, Valter Gattei, Michele Dal Bo
Journal: Blood
Blood (2014) 124 (21): 296.
https://doi.org/10.1182/blood.V124.21.296.296
Published: 2014
Journal Articles

Clinical Significance of Apoptosis in Chronic Lymphocytic Leukemia (CLL)

Giovanni Del Poeta, Maria Ilaria Del Principe, MD, Michele Dal Bo, Francesco Buccisano, MD, Dario Ragusa, Federico Pozzo, Pietro Bulian, Luca Maurillo, MD, Davide Rossi, MD PhD, Adriano Venditti, Paolo de Fabritiis, MD, Gianluca Gaidano, Sergio Amadori, Valter Gattei
Journal: Blood
Blood (2014) 124 (21): 834.
https://doi.org/10.1182/blood.V124.21.834.834
Published: 2014
Journal Articles

Genomic Aberrations Dramatically Improve The Strong Prognostic Impact Of IGHV Mutational Status In Chronic Lymphocytic Leukemia (CLL)

Giovanni Del Poeta, MD, Dario Ragusa, Francesco Buccisano, MD, Michele Dal Bo, Luca Maurillo, MD, Antonella Zucchetto, Maria Ilaria Del Principe, Pasquale Niscola, Davide Rossi, Alessio Pio Perrotti, Adriano Venditti, MD, Paolo de Fabritiis, Valter Gattei, Gianluca Gaidano, Sergio Amadori
Journal: Blood
Blood (2013) 122 (21): 1370.
https://doi.org/10.1182/blood.V122.21.1370.1370
Published: 2013