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Giovanni D'Arena
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Journal Articles

Baseline Characteristics from Arise Study, an Italian Non-Interventional Study Assessing the Real-World Use of Acalabrutinib in the Treatment of Patients with Chronic Lymphocytic Leukemia (CLL)

Francesca Romana Mauro, Andrea Visentin, Luca Laurenti, Susanna Gallo, Vincenzo Pavone, Paolo Nicoli, Massimiliano Postorino, Ilaria Scortechini, Lydia Scarfo, Myriam Foglietta, Chiara Borella, Gaetano Palumbo, Nicola Di Rienzo, Monica Tani, Agostino Tafuri, Paolo Sportoletti, Potito Rosario Scalzulli, Elsa Pennese, Domenico Pastore, Cristina Pasquini, Luigi Malandruccolo, Ambra Di Veroli, Gaetano De Santis, Gioacchino Catania, Anna Tamburini, Caterina Stelitano, Fabrizio Pane, Pellegrino Musto, Massimo Magagnoli, Giovanni D'Arena, Daniele Caracciolo, Deborah Bongiovanni, Gianluigi Reda, Claudia Padrone, Massimo Gentile
Journal: Blood
Blood (2024) 144 (Supplement 1): 7747.
https://doi.org/10.1182/blood-2024-199041
Published: 2024
Journal Articles

High IGHV Intraclonal Diversification Identifies CLL with Good Prognosis, Features of Anergy and Specific T-Cell Profiles

Filippo Vit, Tamara Bittolo, Antonella Zucchetto, Robel Papotti, Erika Tissino, Federico Pozzo, Andrea Stacchetti, Francesca Rossi, Massimo Degan, Eva Zaina, Ilaria Cattarossi, Paola Varaschin, Paola Nanni, Michele Berton, Alessandra Braida, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Azzurra Anna Romeo, Annalisa Biagi, Giovanni D'Arena, Enrica Antonia Martino, Pietro Bulian, Massimo Gentile, Massimiliano Postorino, Laura Ballotta, Francesco Zaja, Francesco Di Raimondo, Maria Ilaria Del Principe, Valter Gattei, Riccardo Bomben
Journal: Blood
Blood (2024) 144 (Supplement 1): 75.
https://doi.org/10.1182/blood-2024-203003
Published: 2024
Journal Articles

A Snapshot of the Management of Chronic Lymphocytic Leukemia in Italy. Preliminary Analysis on over 3000 Patients Enrolled in the Gimema CLL2121 Trial

Lydia Scarfo, Marta Coscia, Alfredo Molteni, Alessandro Rambaldi, Roberto Marasca, Sara Steffanoni, Roberta Murru, Nilla Maschio, Ilaria Scortechini, Carlo Gambacorti-Passerini, Elsa Pennese, Livio Trentin, Riccardo Moia, Lucia Farina, Vanessa Innao, Pellegrino Musto, Alessandro Sanna, Davide Facchinelli, Paolo Falcucci, Massimo Pini, Luca Laurenti, Marzia Varettoni, Ilaria Angeletti, Lorella Orsucci, Angela Rago, Giovanni D'Arena, Lorella Maria Antonia Melillo, Alessandro Maggi, Fiorella Ilariucci, Massimo Massaia, Domenico Pastore, Daniele Vallisa, Paola Fazi, Alfonso Piciocchi, Monica Messina, Francesca Paola Paoloni, Robin Foà, Ilaria Del Giudice, Gian Matteo Rigolin, Antonio Cuneo, Paolo Ghia
Journal: Blood
Blood (2023) 142 (Supplement 1): 6544.
https://doi.org/10.1182/blood-2023-188454
Published: 2023
Journal Articles

An Unsupervised Machine Learning Method Stratifies Chronic Lymphocytic Leukemia Patients in Novel Categories with Different Risk of Early Treatment

Francesca Cuturello, Federico Pozzo, Edith Natalia Villegas Garcia, Francesca Maria Rossi, Massimo Degan, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Paola Varaschin, Alessandra Braida, Michele Berton, Laura Zannier, Filippo Vit, Erika Tissino, Tamara Bittolo, Roberta Laureana, Giovanni D'Arena, Luca Laurenti, Agostino Tafuri, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Stefano Cozzini, Alessio Ansuini, Alberto Cazzaniga, Valter Gattei
Journal: Blood
Blood (2022) 140 (Supplement 1): 4111–4112.
https://doi.org/10.1182/blood-2022-159981
Published: 2022
Journal Articles

Mutations of the Exportin 1 (XPO1) Gene Predict Shorter Time to First Treatment in 1092 Early Stage Chronic Lymphocytic Leukemia Patients. Α Training/Validation Study

Riccardo Moia, MD, Chiara Favini, PhD, Valentina Ferri, PhD, Riccardo Bomben, PhD, Sruthi Sagiraju, MSc, Tamara Bittolo, PhD, Lydia Scarfo, Silvia Bonfiglio, Rossana Maffei, Stefano Baldoni, Sara Raponi, PhD, Valeria Spina, PhD, Alessio Bruscaggin, PhD, Lodovico Terzi di Bergamo, Lorenzo De Paoli, Gloria Margiotta Casaluci, Clara Deambrogi, PhD, Silvia Rasi, Adalgisa Condoluci, MD, Ahad Ahmed Kodipad, Msc, Ramesh Adhinaveni, Msc, Katia Mokabari, Abdurraouf Mokhtar Mahmoud, MSc, Andrea Patriarca, MD, Jacopo Olivieri, Giovanni D'Arena, MD, Francesco Zaja, Annalisa Chiarenza, MD PhD, Giovanni Del Poeta, MD, Antonella Zucchetto, PhD, Francesca Maria Rossi, PhD, Ilaria Del Giudice, MD PhD, Paolo Sportoletti, MD, Roberto Marasca, MD, Paolo Ghia, MD PhD, Robin Foà, MD, Gianluca Gaidano, Davide Rossi, MD PhD, Valter Gattei, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-136389
Published: 2020
Journal Articles

CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression

Erika Tissino, Federico Pozzo, Dania Benedetti, Chiara Caldana, Tamara Bittolo, Francesca Maria Rossi, Riccardo Bomben, Paola Nanni, Hillarj Chivilò, Ilaria Cattarossi, Eva Zaina, Kevin Norris, Jerry Polesel, Massimo Gentile, Giovanni Tripepi, Riccardo Moia, Enrico Santinelli, Idanna Innocenti, Jacopo Olivieri, Giovanni D’Arena, Luca Laurenti, Francesco Zaja, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, Davide Rossi, Chris Pepper, Tanja Nicole Hartmann, Gianluca Gaidano, Giovanni Del Poeta, Valter Gattei, Antonella Zucchetto
Journal: Blood
Blood (2020) 135 (15): 1244–1254.
https://doi.org/10.1182/blood.2019003179
Published: 2020
Includes: Supplemental data
Journal Articles

Preliminary Results of CML1214, a Survey on Ponatinib Compassionate Use in Italy By the Gimema CML Working Party

Carmen Fava, Matteo Emidio Dragani, MD, Paola Boggione, Francesca Paoloni, Luigiana Luciano, Antonella Gozzini, MD, Patrizia Pregno, Elisabetta Abruzzese, MD, Carlo Gambacorti-Passerini, MD, Giorgina Specchia, MD, Chiara Elena, MD, Monia Lunghi, MD, Ester Pungolino, Franca Falzetti, MD, Sara Galimberti, MD PhD, Alessandra Iurlo, MD PhD, Giovanni D'Arena, MD, Giovanni Reddiconto, Claudio Fozza, MD, Micaela Bergamaschi, MD, Enrico Crea, Giuseppe Saglio, MD, Giovanna Rege Cambrin, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2931.
https://doi.org/10.1182/blood-2019-125052
Published: 2019
Journal Articles

A CRISPR/Cas9-Generated Murine Model Reveals Cooperation between BCR Signaling and CDKN2A/2B and TP53 Disruption in Richter Syndrome

Supriya Chakraborty, PhD, Ilaria Fortunati, BS, Claudio Martines, MS, Brijesh Yadav, PhD, Marija Dimishkovska, PhD, Idanna Innocenti, MD PhD, Rosa Fazio, BS, Giovanni D'Arena, MD, Aleksandar Dimovski, MD PhD, Luca Laurenti, MD, Dimitar G Efremov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4278.
https://doi.org/10.1182/blood-2019-128425
Published: 2019
Journal Articles

Comprehensive Characterization of NOTCH1 Mutational Status in Chronic Lymphocytic Leukemia: Clinical Relevance of Subclonal Mutations and Mutation Types

Tiziana D'Agaro, Tamara Bittolo, Vanessa Bravin, Antonella Zucchetto, Michele Dal Bo, Francesca Rossi, Federico Pozzo, Annalisa Chiarenza, Giovanni D'Arena, Gabriele Pozzato, Francesco Zaja, Davide Rossi, MD PhD, Francesco Di Raimondo, MD, Gianluca Gaidano, MD PhD, Giovanni Del Poeta, MD, Pietro Bulian, Valter Gattei, Riccardo Bomben
Journal: Blood
Blood (2016) 128 (22): 3195.
https://doi.org/10.1182/blood.V128.22.3195.3195
Published: 2016
Journal Articles

Chlorambucil PLUS Rituximab As FRONT-LINE Therapy for Elderly and/or Unfit CLL Patients. LONG-TERM Follow-up and Correlation with Biologic-Based Risk Stratification

Luca Laurenti, Idanna Innocenti, MD, Francesco Autore, MD, Raffaella Pasquale, Barbara Vannata, MD, Stefania Ciolli, Francesca Romana Mauro, MD PhD, Donato Mannina, MD, Giovanni Del Poeta, MD, Giovanni D'Arena, MD, Massimo Massaia, MD, Marta Coscia, MD PhD, Stefano Molica, MD, Gabriele Pozzato, MD, Dimitar G Efremov, MD PhD, Roberto Marasca, MD, Piero Galieni, Antonio Cuneo, MD, Sonia Orlando, Alfonso Piciocchi, BS, Riccardo Boncompagni, Donatella Iolanda Vincelli, MD, Anna Marina Liberati, MD, Filomena Russo, Robin Foa
Journal: Blood
Blood (2016) 128 (22): 3240.
https://doi.org/10.1182/blood.V128.22.3240.3240
Published: 2016
Journal Articles

LDH Levels Predict Progression-Free Survival in Treatment-NaÏVe Patients with Trisomy 12 Chronic Lymphocytic Leukemia

Francesco Autore, MD, Paolo Strati, MD, Idanna Innocenti, MD, Francesco Corrente, Livio Trentin, MD, Agostino Cortelezzi, MD, Marta Coscia, MD PhD, Alessandro Gozzetti, MD, Massimo Gentile, MD, Fortunato Morabito, MD, Giovanni D'Arena, MD, Roberta Murru, MD, Donatella Iolanda Vincelli, MD, Gianluigi Reda, MD, Candida Vitale, MD, Alessandra Ferrajoli, MD, Luca Laurenti
Journal: Blood
Blood (2016) 128 (22): 3211.
https://doi.org/10.1182/blood.V128.22.3211.3211
Published: 2016
Journal Articles

Real Life, Retrospective Analysis of Bortezomib Re-Use As Second Treatment for Relapsed Multiple Myeloma Patients Previously Exposed to Bortezomib-Based Therapies As First Line: The Rebound Study

Pellegrino Musto, MD, Vittorio Simeon, PhD, Nicola Cascavilla, MD, Antonietta Falcone, MD, Maria Teresa Petrucci, MD, Laura Cesini, MD, Francesco Di Raimondo, MD, Concetta Conticello, MD, Roberto Ria, MD, Lucio Catalano, MD, Dalila Salvatore, MD, Lucia Mastrullo, MD, Alfredo Gagliardi, MD, Oreste Villani, MD, Giuseppe Pietrantuono, MD, Giovanni D'Arena, MD, Giovanna Mansueto, MD, Andrea Patriarca, MD, Sara Bringhen, MD, Mariella Genuardi, MD, Nicola Di Renzo, MD, Giovanni Reddiconto, MD, Alberto Fragasso, MD, Tommaso Caravita, MD, Silvia Mangiacavalli, MD, Antonio Palumbo, MD, Alessandro Corso, MD
Journal: Blood
Blood (2016) 128 (22): 4494.
https://doi.org/10.1182/blood.V128.22.4494.4494
Published: 2016
Journal Articles

Characterization and Prognostic Relevance of Circulating Microvesicles in Chronic Lymphocytic Leukemia

Luciana De Luca, Giovanni D'Arena, MD, Vittorio Simeon, PhD, Stefania Trino, PhD, Ilaria Laurenzana, PhD, Antonella Caivano, Francesco La Rocca, Oreste Villani, MD, Giovanna Mansueto, MD, Silvia Deaglio, MD PhD, Idanna Innocenti, MD, Luca Laurenti, Stefano Molica, MD, Giuseppe Pietrantuono, MD, Angelo De Stradis, Luigi Del Vecchio, MD, Pellegrino Musto, MD
Journal: Blood
Blood (2016) 128 (22): 4375.
https://doi.org/10.1182/blood.V128.22.4375.4375
Published: 2016
Journal Articles

Lack of Prognostic Significance of the Conventional and Novel Prognostic Markers in Trisomy 12 Chronic Lymphocytic Leukemia (CLL)

Valter Gattei, Riccardo Bomben, Michele Dal Bo, Antonella Zucchetto, Francesca Rossi, Massimo Degan, Federico Pozzo, Tamara Bittolo, Vanessa Bravin, Tiziana D'Agaro, Claudia Perini, Annalisa Chiarenza, Kari G. Chaffee, MS, Giovanni D'Arena, MD, Francesco Zaja, Gabriele Pozzato, MD, Francesco Di Raimondo, MD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Gianluca Gaidano, MD PhD, Tait D. Shanafelt, MD, Pietro Bulian
Journal: Blood
Blood (2016) 128 (22): 4354.
https://doi.org/10.1182/blood.V128.22.4354.4354
Published: 2016
Journal Articles

Mutations at 3' Untranslated Region (3'UTR) of NOTCH1 Are Associated with Low CD20 Expression Levels in Chronic Lymphocytic Leukemia

Tamara Bittolo, Federico Pozzo, Riccardo Bomben, Tiziana D'Agaro, Vanessa Bravin, Pietro Bulian, Francesca Rossi, Antonella Zucchetto, Massimo Degan, Paolo Macor, Giovanni D'Arena, Annalisa Chiarenza, Francesco Zaja, Gabriele Pozzato, Francesco Di Raimondo, MD, Davide Rossi, Gianluca Gaidano, Giovanni Del Poeta, MD, Valter Gattei, Michele Dal Bo
Journal: Blood
Blood (2016) 128 (22): 306.
https://doi.org/10.1182/blood.V128.22.306.306
Published: 2016
Journal Articles

SLAMF1/CD150 Activates Autophagy in Chronic Lymphocytic Leukemia Cells, Modulating Chemotaxis and Responses to Therapy

Cinzia Bologna, Roberta Buonincontri, PhD, Sara Serra, PhD, Tiziana Vaisitti, PhD, Valentina Audrito, PhD, Davide Brusa, PhD, Andrea Pagnani, Marta Coscia, Giovanni D'Arena, Erica B. Bhavsar, Richard R. Furman, Davide Rossi, MD PhD, Gianluca Gaidano, Cox Terhorst, Silvia Deaglio
Journal: Blood
Blood (2015) 126 (23): 1728.
https://doi.org/10.1182/blood.V126.23.1728.1728
Published: 2015
Journal Articles

NOTCH1 Mutated IGHV Unmutated Chronic Lymphocytic Leukemia Cells Are Characterized By a Constitutive Overexpression of Nucleophosmin-1 and Ribosome-Associated Components

Federico Pozzo, Tamara Bittolo, Erika Tissino, Francesca Maria Rossi, Riccardo Bomben, Antonella Zucchetto, Dania Benedetti, Francesca Arruga, PhD, Branimir Gizdic, Massimo Degan, Pietro Bulian, Giovanni D'Arena, Francesco Di Raimondo, MD, Francesco Zaja, Gabriele Pozzato, Alberto Zamò, MD PhD, Silvia Deaglio, MD PhD, Davide Rossi, Gianluca Gaidano, Giovanni Del Poeta, Michele Dal Bo, Valter Gattei
Journal: Blood
Blood (2014) 124 (21): 3308.
https://doi.org/10.1182/blood.V124.21.3308.3308
Published: 2014
Journal Articles

NOTCH1 Mutations Are Associated with Low CD20 Expression in Chronic Lymphocytic Leukemia: Evidences for a NOTCH1 -Mediated Epigenetic Regulatory Mechanism

Federico Pozzo, Tamara Bittolo, Pietro Bulian, Erika Tissino, Francesca Maria Rossi, Paolo Macor, PhD, Riccardo Bomben, Antonella Zucchetto, Dania Benedetti, Francesca Arruga, PhD, Branimir Gizdic, Massimo Degan, Giovanni D'Arena, Francesco Di Raimondo, MD, Francesco Zaja, Gabriele Pozzato, Silvia Deaglio, MD PhD, Davide Rossi, MD PhD, Gianluca Gaidano, MD, Giovanni Del Poeta, Valter Gattei, Michele Dal Bo
Journal: Blood
Blood (2014) 124 (21): 296.
https://doi.org/10.1182/blood.V124.21.296.296
Published: 2014
Journal Articles

Bendamustine with Rituximab Is Safe and Effective As FRONT LINE Therapy in Elderly B-CLL Patients. an ITALIAN RETROSPECTIVE MULTICENTER Experience

Luca Laurenti, MD, Francesco Autore, MD, Idanna Innocenti, Barbara Vannata, Maria Cantonetti, MD, Maria Ilaria Del Principe, Francesca Romana Mauro, Anticoli Borza Paola, Velia Bongarzoni, Stefania Ciolli, MD, Riccardo Boncompagni, Mariarita Sciumé, MD, Daniele Vincenti, MD, Francesco Ghio, MD, Nadia Cecconi, Vincenzo Pitini, Patrizia Mondello, Maria Rosa Lanza Cariccio, Alessandro Gozzetti, Giovanni D'Arena, Roberta Murru, MD, Nicola Piccirillo, Mario Petrini, MD PhD, Agostino Cortelezzi, MD, Giovanni Del Poeta, Robin Foà, MD, Simona Sica, MD
Journal: Blood
Blood (2014) 124 (21): 5655.
https://doi.org/10.1182/blood.V124.21.5655.5655
Published: 2014
Journal Articles

Functional Effects Of NOTCH1 Mutations In Chronic Lymphocytic Leukemia Patients

Francesca Arruga, PhD, Branimir Gizdic, Sara Serra, Tiziana Vaisitti, PhD, Davide Rossi, Marta Coscia, MD, PhD, Luca Laurenti, MD, Giovanni D'Arena, Ozren Jaksic, MD, PhD, Giorgio Inghirami, Gianluca Gaidano, Silvia Deaglio, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4117.
https://doi.org/10.1182/blood.V122.21.4117.4117
Published: 2013