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Gabriele Pozzato
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Journal Articles

CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression

Erika Tissino, Federico Pozzo, Dania Benedetti, Chiara Caldana, Tamara Bittolo, Francesca Maria Rossi, Riccardo Bomben, Paola Nanni, Hillarj Chivilò, Ilaria Cattarossi, Eva Zaina, Kevin Norris, Jerry Polesel, Massimo Gentile, Giovanni Tripepi, Riccardo Moia, Enrico Santinelli, Idanna Innocenti, Jacopo Olivieri, Giovanni D’Arena, Luca Laurenti, Francesco Zaja, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, Davide Rossi, Chris Pepper, Tanja Nicole Hartmann, Gianluca Gaidano, Giovanni Del Poeta, Valter Gattei, Antonella Zucchetto
Journal: Blood
Blood (2020) 135 (15): 1244–1254.
https://doi.org/10.1182/blood.2019003179
Published: 2020
Includes: Supplemental data
Journal Articles

Clinical Impact of Clonal and Subclonal TP53 Mutations and Deletions in Chronic Lymphocytic Leukemia: An Italian Multicenter Experience

Riccardo Bomben, PhD, Francesca Maria Rossi, PhD, Tiziana D'Agaro, Fellow, Tamara Bittolo, PhD, Filippo Vit, MSc, Antonella Zucchetto, Erika Tissino, PhD, Federico Pozzo, MSc, Mario Ballerini, MD, Pietro Bulian, Massimo Degan, PhD, Jerry Polesel, Eva Zaina, Ilaria Cattarossi, Paola Nanni, Hillarj Chivilò, Giovanni Francesco D'Arena, MD, Enrico Santinelli, MD, Annalisa Biagi, MD, Annalisa Chiarenza, MD PhD, Francesco Zaja, MD, Gabriele Pozzato, MD, Francesco Di Raimondo, MD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Valter Gattei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 480.
https://doi.org/10.1182/blood-2019-124647
Published: 2019
Journal Articles

The VLA-4 Integrin Is Constitutively Activated in a Fraction of CD49d-Expressing Chronic Lymphocytic Leukemia Via Autonomous BCR-Mediated Signaling

Erika Tissino, PhD, Tamara Bittolo, PhD, Dania Benedetti, PhD, Riccardo Bomben, PhD, Andrea Härzschel, Palash Maity, Gabriela Forestieri, Antonella Nicolò, M.Sc; B.Sc., Moumita Datta, Enrico Santinelli, MD, Francesca Maria Rossi, PhD, Alexandre Chigaev, Larry A. Sklar, Francesco Zaja, MD, Gabriele Pozzato, MD, Pietro Bulian, MD, Giovanni Francesco D'Arena, MD, Annalisa Chiarenza, MD PhD, Francesco Di Raimondo, MD, Hassan Jumaa, PhD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Tanja Nicole Hartmann, Antonella Zucchetto, Valter Gattei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 849.
https://doi.org/10.1182/blood-2019-124313
Published: 2019
Journal Articles

A Laboratory Based Scoring System Predicts Early Treatment in Rai 0/Binet a CLL

Jared A Cohen, MD, Francesca Maria Rossi, PhD, Riccardo Bomben, PhD, Lodovico Terzi-di-Bergamo, Pietro Bulian, MD, Massimo Degan, PhD, Antonella Zucchetto, Giovanni Francesco D'Arena, MD, Enrico Santinelli, MD, Francesco Zaja, MD, Gabriele Pozzato, MD, Davide Rossi, MD PhD, Annalisa Chiarenza, MD PhD, Francesco Di Raimondo, MD, Luca Laurenti, MD, Idanna Innocenti, MD, Giovanni Del Poeta, MD, Christopher Fegan, MD, Chris Pepper, BSc, PhD, Kari G. Chaffee, MS, Sameer A. Parikh, MD, Neil E. Kay, MD, Valter Gattei, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4399.
https://doi.org/10.1182/blood-2018-99-112162
Published: 2018
Journal Articles

SF3B1 Mutations Associate with Low CD20 Expression in CLL: Another NOTCH1 -Dependent Mechanism?

Federico Pozzo, PhD, Tamara Bittolo, PhD, Erika Tissino, PhD, Filippo Vit, MSc, Elena Vendramini, PhD, Riccardo Bomben, PhD, Antonella Zucchetto, Michele Dal Bo, PhD, Luca Laurenti, MD, Giovanni Francesco D'Arena, MD, Francesco Di Raimondo, MD, Annalisa Chiarenza, MD PhD, Gabriele Pozzato, MD, Francesco Zaja, MD, Giovanni Del Poeta, MD, Valter Gattei, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1838.
https://doi.org/10.1182/blood-2018-99-111894
Published: 2018
Journal Articles

Intraclonal Diversification Occurs in Chronic Lymphocytic Leukemia Expressing B Cell Receptors Belonging to the IGHV4 Gene Family

Filippo Vit, MSc, Francesca Maria Rossi, PhD, Tiziana D'Agaro, Fellow, Tamara Bittolo, PhD, Antonella Zucchetto, Erika Tissino, PhD, Federico Pozzo, PhD, Pietro Bulian, MD, Massimo Degan, PhD, Eva Zaina, Ilaria Cattarossi, Paola Nanni, Hillarj Chivilò, Giovanni Francesco D'Arena, MD, Enrico Santinelli, MD, Annalisa Chiarenza, MD PhD, Francesco Zaja, MD, Gabriele Pozzato, MD, Francesco Di Raimondo, MD, Giovanni Del Poeta, MD, Valter Gattei, MD, Riccardo Bomben, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 944.
https://doi.org/10.1182/blood-2018-99-112423
Published: 2018
Journal Articles

Clinical Impact of Clonal and Subclonal TP53 Mutations in Chronic Lymphocytic Leukemia

Riccardo Bomben, PhD, Maria Francesca Rossi, PhD, Tiziana D'Agaro, Fellow, Tamara Bittolo, PhD, Antonella Zucchetto, Erika Tissino, PhD, Federico Pozzo, PhD, Filippo Vit, MSc, Pietro Bulian, MD, Massimo Degan, PhD, Eva Zaina, Ilaria Cattarossi, Paola Nanni, Hillarj Chivilò, Giovanni Francesco D'Arena, MD, Annalisa Chiarenza, MD PhD, Enrico Santinelli, MD, Francesco Zaja, MD, Gabriele Pozzato, MD, Francesco Di Raimondo, MD, Giovanni Del Poeta, MD, Valter Gattei, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 945.
https://doi.org/10.1182/blood-2018-99-111452
Published: 2018
Journal Articles

The VLA-4 Integrin Is Constitutively Activated in a Subset of CD49d-Expressing CLL: A Relationship with the Autonomous BCR-Mediated Signaling?

Erika Tissino, PhD, Tamara Bittolo, PhD, Dania Benedetti, PhD, Riccardo Bomben, PhD, Gabriela Forestieri, Eva Szenes, Andrea Haerzschel, PhD, Enrico Santinelli, MD, Maria Francesca Rossi, PhD, Alexandre Chigaev, Larry A. Sklar, Francesco Zaja, MD, Pietro Bulian, MD, Giovanni Francesco D'Arena, MD, Annalisa Chiarenza, MD PhD, Francesco Di Raimondo, MD, Gabriele Pozzato, MD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Tanja N. Hartmann, PhD, Antonella Zucchetto, Valter Gattei, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5531.
https://doi.org/10.1182/blood-2018-99-111450
Published: 2018
Journal Articles

The Engineered MIPI (e-MIPI), a Candidate Data-Mining Based Mantle Cell Lymphoma Prognostic Index Developed from the Dataset of the Fondazione Italiana Linfomi (FIL) MCL0208 Phase III Trial

Gian Maria Zaccaria, PhD, Simone Ferrero, MD, Roberto Passera, PhD, Andrea Evangelista, PhD, Mariella Loschirico, MD, Irene Dogliotti, MD, Marco Ghislieri, Elisa Genuardi, PhD, Riccardo Bomben, PhD, Valter Gattei, MD, Giovannino Ciccone, Monica Tani, MD, Gianluca Gaidano, MD PhD, Stefano Volpetti, MD, Maria Giuseppina Cabras, MD, Nicola Di Renzo, MD, Francesco Merli, MD, Daniele Vallisa, MD, Michele Spina, MD, Anna Pascarella, MD, Giancarlo Latte, MD, Caterina Patti, Gabriele Pozzato, MD, Alberto Fabbri, MD, Sergio Cortelazzo, MD, Marco Ladetto
Journal: Blood
Blood (2018) 132 (Supplement 1): 2890.
https://doi.org/10.1182/blood-2018-99-114168
Published: 2018
Journal Articles

KRAS , NRAS and BRAF Mutations Are Highly Enriched in TRI12 Chronic Lymphocytic Leukemia and Are Associated to Shorter Time to First Treatment

Elena Vendramini, PhD, Riccardo Bomben, PhD, Federico Pozzo, PhD, Dania Benedetti, PhD, Maria Francesca Rossi, PhD, Michele Dal Bo, PhD, Gabriele Pozzato, MD, Francesco Zaja, MD, Annalisa Chiarenza, MD PhD, Francesco Di Raimondo, MD, Giovanni Del Poeta, MD, Valter Gattei, MD, Antonella Zucchetto
Journal: Blood
Blood (2018) 132 (Supplement 1): 3113.
https://doi.org/10.1182/blood-2018-99-111864
Published: 2018
Journal Articles

HIF-1α Upregulation in TP53 Disrupted Chronic Lymphocytic Leukemia Cells and Its Potential Role As a Therapeutic Target

Valentina Griggio, Ms, Candida Vitale, MD, Maria Todaro, PhD, Chiara Riganti, MD, Joanna Kopecka, PhD, Michele Dal Bo, Davide Rossi, Gabriele Pozzato, MD, Monia Marchetti, MD PhD, Marina Ruggeri, Paola Omedè, PhD, Luca Laurenti, Giovanni Del Poeta, MD, Francesca Romana Mauro, MD PhD, Valter Gattei, Gianluca Gaidano, MD PhD, Robin Foa, Massimo Massaia, MD, Mario Boccadoro, MD, Marta Coscia, MD PhD
Journal: Blood
Blood (2016) 128 (22): 305.
https://doi.org/10.1182/blood.V128.22.305.305
Published: 2016
Journal Articles

Mutations at 3' Untranslated Region (3'UTR) of NOTCH1 Are Associated with Low CD20 Expression Levels in Chronic Lymphocytic Leukemia

Tamara Bittolo, Federico Pozzo, Riccardo Bomben, Tiziana D'Agaro, Vanessa Bravin, Pietro Bulian, Francesca Rossi, Antonella Zucchetto, Massimo Degan, Paolo Macor, Giovanni D'Arena, Annalisa Chiarenza, Francesco Zaja, Gabriele Pozzato, Francesco Di Raimondo, MD, Davide Rossi, Gianluca Gaidano, Giovanni Del Poeta, MD, Valter Gattei, Michele Dal Bo
Journal: Blood
Blood (2016) 128 (22): 306.
https://doi.org/10.1182/blood.V128.22.306.306
Published: 2016
Journal Articles

Comprehensive Characterization of NOTCH1 Mutational Status in Chronic Lymphocytic Leukemia: Clinical Relevance of Subclonal Mutations and Mutation Types

Tiziana D'Agaro, Tamara Bittolo, Vanessa Bravin, Antonella Zucchetto, Michele Dal Bo, Francesca Rossi, Federico Pozzo, Annalisa Chiarenza, Giovanni D'Arena, Gabriele Pozzato, Francesco Zaja, Davide Rossi, MD PhD, Francesco Di Raimondo, MD, Gianluca Gaidano, MD PhD, Giovanni Del Poeta, MD, Pietro Bulian, Valter Gattei, Riccardo Bomben
Journal: Blood
Blood (2016) 128 (22): 3195.
https://doi.org/10.1182/blood.V128.22.3195.3195
Published: 2016
Journal Articles

Chlorambucil PLUS Rituximab As FRONT-LINE Therapy for Elderly and/or Unfit CLL Patients. LONG-TERM Follow-up and Correlation with Biologic-Based Risk Stratification

Luca Laurenti, Idanna Innocenti, MD, Francesco Autore, MD, Raffaella Pasquale, Barbara Vannata, MD, Stefania Ciolli, Francesca Romana Mauro, MD PhD, Donato Mannina, MD, Giovanni Del Poeta, MD, Giovanni D'Arena, MD, Massimo Massaia, MD, Marta Coscia, MD PhD, Stefano Molica, MD, Gabriele Pozzato, MD, Dimitar G Efremov, MD PhD, Roberto Marasca, MD, Piero Galieni, Antonio Cuneo, MD, Sonia Orlando, Alfonso Piciocchi, BS, Riccardo Boncompagni, Donatella Iolanda Vincelli, MD, Anna Marina Liberati, MD, Filomena Russo, Robin Foa
Journal: Blood
Blood (2016) 128 (22): 3240.
https://doi.org/10.1182/blood.V128.22.3240.3240
Published: 2016
Journal Articles

FcμR Triggering Activates BCR Signaling Pathways and Increases Survival of CLL Cells

Stefania Gobessi, PhD, Binu K Sasi, PhD, Gabriele Pozzato, MD, Idanna Innocenti, MD, Luca Laurenti, Dimitar G Efremov, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2015.
https://doi.org/10.1182/blood.V128.22.2015.2015
Published: 2016
Journal Articles

Lack of Prognostic Significance of the Conventional and Novel Prognostic Markers in Trisomy 12 Chronic Lymphocytic Leukemia (CLL)

Valter Gattei, Riccardo Bomben, Michele Dal Bo, Antonella Zucchetto, Francesca Rossi, Massimo Degan, Federico Pozzo, Tamara Bittolo, Vanessa Bravin, Tiziana D'Agaro, Claudia Perini, Annalisa Chiarenza, Kari G. Chaffee, MS, Giovanni D'Arena, MD, Francesco Zaja, Gabriele Pozzato, MD, Francesco Di Raimondo, MD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Gianluca Gaidano, MD PhD, Tait D. Shanafelt, MD, Pietro Bulian
Journal: Blood
Blood (2016) 128 (22): 4354.
https://doi.org/10.1182/blood.V128.22.4354.4354
Published: 2016
Journal Articles

The B-Cell Receptor Signaling Inhibitor Molecules CD305 and CD307b Are Markers of Favorable Prognosis in Chronic Lymphocytic Leukemia with Both Mutated and Unmutated IGHV Gene Status

Dania Benedetti, Claudia Perini, Erika Tissino, Michele Dal Bo, Pietro Bulian, Riccardo Bomben, Francesca Rossi, Massimo Degan, Alessandro Poggi, Mahdi Shabani, Fazel Shokri, Francesco Zaja, MD, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, MD, Giovanni Del Poeta, MD, Valter Gattei, Antonella Zucchetto
Journal: Blood
Blood (2016) 128 (22): 4358.
https://doi.org/10.1182/blood.V128.22.4358.4358
Published: 2016
Journal Articles

BCR signaling inhibitors differ in their ability to overcome Mcl-1–mediated resistance of CLL B cells to ABT-199

Kamil Bojarczuk, Binu K. Sasi, Stefania Gobessi, Idanna Innocenti, Gabriele Pozzato, Luca Laurenti, Dimitar G. Efremov
Journal: Blood
Blood (2016) 127 (25): 3192–3201.
https://doi.org/10.1182/blood-2015-10-675009
Published: 2016
Includes: Supplemental data
Journal Articles

CD49d Prevails over the Novel Recurrent Mutations As Independent Prognosticator of Overall Survival in Chronic Lymphocytic Leukemia

Michele Dal Bo, Pietro Bulian, Riccardo Bomben, Antonella Zucchetto, Francesca Rossi, Federico Pozzo, Tamara Bittolo, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Hillarj Chivilò, Massimo Degan, Francesco Zaja, MD, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, MDPhD, Giovanni Del Poeta, Pr, MD, Davide Rossi, MD PhD, Gianluca Gaidano, Valter Gattei
Journal: Blood
Blood (2015) 126 (23): 1706.
https://doi.org/10.1182/blood.V126.23.1706.1706
Published: 2015
Journal Articles

The Concomitant High Expression of the B-Cell Receptor Signaling Inhibitor Molecules CD150, CD305, and CD307b Predicts Longer Overall Survival in the Context of Low-Risk Chronic Lymphocytic Leukemia

Antonella Zucchetto, Dania Benedetti, Chiara Caldana, Erika Tissino, Michele Dal Bo, Pietro Bulian, Riccardo Bomben, Francesca Rossi, Francesco Zaja, MD, Gabriele Pozzato, Annalisa Chiarenza, Francesco Di Raimondo, MDPhD, Giovanni Del Poeta, Valter Gattei
Journal: Blood
Blood (2015) 126 (23): 1720.
https://doi.org/10.1182/blood.V126.23.1720.1720
Published: 2015