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Karen A. Urtishak
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Journal Articles

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Karen A. Urtishak, PhD, Wang Li-San, PhD, David T. Teachey, MD, Tasian K. Sarah, MD, Jeffrey S. Barrett, PhD, I-Ming L. Chen, Susan R. Atlas, PhD, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Carolyn A. Felix, MD
Journal: Blood
Blood (2013) 122 (21): 1669.
https://doi.org/10.1182/blood.V122.21.1669.1669
Published: 2013
Journal Articles

Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia

Karen A. Urtishak, Alena Y. Z. Edwards, Li-San Wang, Amanda Hudome, Blaine W. Robinson, Jeffrey S. Barrett, Kajia Cao, Lori Cory, Jonni S. Moore, Andrew D. Bantly, Qian-Chun Yu, I-Ming L. Chen, Susan R. Atlas, Cheryl L. Willman, Mondira Kundu, Andrew J. Carroll, Nyla A. Heerema, Meenakshi Devidas, Joanne M. Hilden, ZoAnn E. Dreyer, Stephen P. Hunger, Gregory H. Reaman, Carolyn A. Felix
Journal: Blood
Blood (2013) 121 (14): 2689–2703.
https://doi.org/10.1182/blood-2012-04-425033
Published: 2013
Includes: Supplemental data
Journal Articles

Predicting Clinical Dose-Exposure and Exposure-Response Relationships of Pan-Antiapoptotic BCL-2 Family Inhibitor Obatoclax in MLL Rearranged Infant Leukemias From Preclinical Disease Models and Adult Experience

Jeffrey S Barrett, PhD, Alena Y. Zhang, PhD, Karen A. Urtishak, PhD, Gwenn Danet-Desnoyers, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Carolyn A. Felix, MD
Journal: Blood
Blood (2011) 118 (21): 2580.
https://doi.org/10.1182/blood.V118.21.2580.2580
Published: 2011
Journal Articles

Unique Familial MLL -rearranged Precursor B Cell Infant Acute Lymphoblastic Leukemia (ALL) in Non-Twin Siblings

Karen A. Urtishak, PhD, Blaine W. Robinson, PhD, Jaclyn A. Biegel, PhD, Kim E. Nichols, MD, Julie W. Stern, MD, Carolyn A. Felix, MD
Journal: Blood
Blood (2011) 118 (21): 2417.
https://doi.org/10.1182/blood.V118.21.2417.2417
Published: 2011
Journal Articles

Mechanisms in Leukemia-Associated Chromosomal Translocations: Novel, High-Throughput Sequencing Method to Detect Topoisomerase II (TOP2) Cleavage Complexes Genome-Wide with Exact Base Resolution,

Carolyn A. Felix, MD, Marie L. Carillo, MS, Karen A. Urtishak, PhD, Isabelle C. Dragomir, BS, Michele E. Paessler, DO, Andrew D. Bantly, BS, Marybeth Helfrich, BS, Li-San Wang, PhD, Brian D. Gregory, PhD
Journal: Blood
Blood (2011) 118 (21): 3445.
https://doi.org/10.1182/blood.V118.21.3445.3445
Published: 2011
Journal Articles

Infant Acute Lymphoblastic Leukemias Are Pan-Sensitive to Obatoclax Across molecular/Cytogenetic Subtypes, Especially MLL - ENL , and gene Expression Profiles Determine Obatoclax IC 50 : A Report on the Children's Oncology Group (COG) P9407 Trial

Karen A. Urtishak, PhD, Li-San Wang, PhD, Richard Harvey, PhD, Susan R Atlas, PhD, I-Ming L. Chen, DVM, MS, Blaine W. Robinson, PhD, Lea Moukarzel, Kajia Cao, PhD, Meenakshi Devidas, PhD, Andrew J. Carroll, PhD, Nyla A. Heerema, Ph.D., Stephen Hunger, MD, Gregory H. Reaman, MD, Joanne M. Hilden, MD, Bruce Camitta, MD, Naomi Winick, MD, William L. Carroll, MD, Alena Y. Zhang, PhD, Lori Cory, Steven Mc Veigh, Jeffery S. Barrett, PhD, Zoann E. Dreyer, MD, Cheryl L. Willman, MD, Carolyn A. Felix, MD
Journal: Blood
Blood (2010) 116 (21): 2757.
https://doi.org/10.1182/blood.V116.21.2757.2757
Published: 2010