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Li-San Wang
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Journal Articles

Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia

Karen A. Urtishak, Alena Y. Z. Edwards, Li-San Wang, Amanda Hudome, Blaine W. Robinson, Jeffrey S. Barrett, Kajia Cao, Lori Cory, Jonni S. Moore, Andrew D. Bantly, Qian-Chun Yu, I-Ming L. Chen, Susan R. Atlas, Cheryl L. Willman, Mondira Kundu, Andrew J. Carroll, Nyla A. Heerema, Meenakshi Devidas, Joanne M. Hilden, ZoAnn E. Dreyer, Stephen P. Hunger, Gregory H. Reaman, Carolyn A. Felix
Journal: Blood
Blood (2013) 121 (14): 2689–2703.
https://doi.org/10.1182/blood-2012-04-425033
Published: 2013
Includes: Supplemental data
Journal Articles

Mechanisms in Leukemia-Associated Chromosomal Translocations: Novel, High-Throughput Sequencing Method to Detect Topoisomerase II (TOP2) Cleavage Complexes Genome-Wide with Exact Base Resolution,

Carolyn A. Felix, MD, Marie L. Carillo, MS, Karen A. Urtishak, PhD, Isabelle C. Dragomir, BS, Michele E. Paessler, DO, Andrew D. Bantly, BS, Marybeth Helfrich, BS, Li-San Wang, PhD, Brian D. Gregory, PhD
Journal: Blood
Blood (2011) 118 (21): 3445.
https://doi.org/10.1182/blood.V118.21.3445.3445
Published: 2011
Journal Articles

Infant Acute Lymphoblastic Leukemias Are Pan-Sensitive to Obatoclax Across molecular/Cytogenetic Subtypes, Especially MLL - ENL , and gene Expression Profiles Determine Obatoclax IC 50 : A Report on the Children's Oncology Group (COG) P9407 Trial

Karen A. Urtishak, PhD, Li-San Wang, PhD, Richard Harvey, PhD, Susan R Atlas, PhD, I-Ming L. Chen, DVM, MS, Blaine W. Robinson, PhD, Lea Moukarzel, Kajia Cao, PhD, Meenakshi Devidas, PhD, Andrew J. Carroll, PhD, Nyla A. Heerema, Ph.D., Stephen Hunger, MD, Gregory H. Reaman, MD, Joanne M. Hilden, MD, Bruce Camitta, MD, Naomi Winick, MD, William L. Carroll, MD, Alena Y. Zhang, PhD, Lori Cory, Steven Mc Veigh, Jeffery S. Barrett, PhD, Zoann E. Dreyer, MD, Cheryl L. Willman, MD, Carolyn A. Felix, MD
Journal: Blood
Blood (2010) 116 (21): 2757.
https://doi.org/10.1182/blood.V116.21.2757.2757
Published: 2010
Journal Articles

Pan-Anti-Apoptotic BCL-2 Family Inhibitor, Obatoclax, Activates Autophagic Cell Death Pathway and Has Potent Cytotoxicity in Infant and Pediatric MLL -Rearranged Leukemias

Alena Y. Zhang, PharmD, PhD, Blaine W. Robinson, PhD, Li-San Wang, PhD, Kajia Kao, PhD, Lori Cory, Jeffrey S. Barrett, PhD, Susan Atlas, PhD, I-Ming Chen, MS, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Meenakshi Devidas, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Jonni S. Moore, PhD, Craig B. Thompson, MD, Mondira Kundu, MD, PhD, Carolyn A. Felix, MD
Journal: Blood
Blood (2008) 112 (11): 2647.
https://doi.org/10.1182/blood.V112.11.2647.2647
Published: 2008
Journal Articles

Age Is the Strongest Determinant of Leukemia Blast Cell Gene Expression in MLL -Rearranged Infant ALL and MLL-AF4 Directs a Distinct Gene Expression Profile Related to CNS Disease.

Blaine W. Robinson, PhD, Kajia Cao, PhD, Joanne M. Hilden, MD, Patricia A. Dinndorf, MD, Nyla A. Heerema, PhD, Harland N. Sather, Ron McGlennen, Stephen P. Hunger, MD, Gregory H. Reaman, MD, Li-San Wang, PhD, Carolyn A. Felix, MD
Journal: Blood
Blood (2008) 112 (11): 1200.
https://doi.org/10.1182/blood.V112.11.1200.1200
Published: 2008
Journal Articles

Cell Death Regulatory Gene Expression Correlates with MLL Rearrangement Status and Prognostic Clinical Covariates in Acute Leukemia in Infants.

Alena Y. Zhang, PharmD, PhD, Blaine W. Robinson, PhD, Kajia Kao, PhD, Kathryn Behling, MD, PhD, Meenakshi Devidas, PhD, Todd Alonzo, PhD, Susana C. Raimondi, PhD, Andrew Carroll, PhD, Robert J. Arceci, MD, PhD, Alan Gamis, MD, Stephen P. Hunger, MD, Gregory H. Reaman, MD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Li-San Wang, PhD, Carolyn A. Felix, MD
Journal: Blood
Blood (2008) 112 (11): 2255.
https://doi.org/10.1182/blood.V112.11.2255.2255
Published: 2008