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Journal Articles

Trajectory Inference Highlights Dynamic Expression of T-Cell Development Genes in Pediatric T-Cell Acute Lymphoblastic Leukemia

Irina Pushel, Byunggil Yoo, Daniel Louiselle, Margaret Gibson, Erin M. Guest, Midhat S Farooqi, Keith J. August
Journal: Blood
Blood (2023) 142 (Supplement 1): 2983.
https://doi.org/10.1182/blood-2023-187434
Published: 2023
Journal Articles

Single-Cell RNA Sequencing Facilitates Study of Cancer Mechanisms across Pediatric Leukemias

Irina Pushel, Byunggil Yoo, Daniel Louiselle, Margaret Gibson, Alan S Gamis, Keith J. August, Terrie Flatt, Tomi Pastinen, Erin M. Guest, Midhat S Farooqi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1614.
https://doi.org/10.1182/blood-2023-187340
Published: 2023
Journal Articles

Single-Cell Transcriptomics Reveals Similarity of Aggressive Infant Acute Lymphoblastic Leukemia Cells to Early Hematopoietic Progenitors

Irina Pushel, Midhat S. Farooqi, Byunggil Yoo, Kai Tan, Kathrin M. Bernt, Erin Guest
Journal: Blood
Blood (2022) 140 (Supplement 1): 6339–6340.
https://doi.org/10.1182/blood-2022-170028
Published: 2022
Journal Articles

Single-Cell Genomic Analysis Identifies Prognostically Significant Gene Expression Programs in Infant Acute Lymphoblastic Leukemia

Irina Pushel, Midhat S. Farooqi, Byunggil Yoo, Daniel Louiselle, Tomi Pastinen, Patrick A. Brown, Erin Guest
Journal: Blood
Blood (2021) 138 (Supplement 1): 3480.
https://doi.org/10.1182/blood-2021-152828
Published: 2021
Journal Articles

Germline Variants Associated with Cancer Predisposition and Bone Marrow Failure Are Common in KMT2A- r Infant Acute Lymphoblastic Leukemia Patients

Sarah Mc Dermott, DO, Midhat S. Farooqi, MD PhD, Azhar Saeed, MD, Byunggil Yoo, MS, Emily Farrow, PhD CGC, Neil Miller, Patrick A. Brown, MD, Erin Guest, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41.
https://doi.org/10.1182/blood-2020-139564
Published: 2020
Journal Articles

Single Cell Sequencing Reveals Heterogeneity of Gene Expression in KMT2A Rearranged Infant ALL at Relapse Compared to Diagnosis

Erin Guest, MD, Byunggil Yoo, MS, Rumen Kostadinov, PhD, Midhat S. Farooqi, MD PhD, Emily Farrow, PhD CGC, Margaret Gibson, Neil Miller, Karina Shah, Tomi Pastinen, MD PhD, Patrick A. Brown, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2756.
https://doi.org/10.1182/blood-2019-131999
Published: 2019
Journal Articles

Whole Genome Bisulfite Sequencing (WGBS) Robustly Measures the Pharmacodynamic Effect of Decitabine/Vorinostat Epigenetic Treatment in Relapsed Pediatric ALL Demonstrating Potent Hypomethylation Associated with Upregulation of PRC2 and TP53 Targets

Rumen Kostadinov, PhD, Byunggil Yoo, MS, Midhat S. Farooqi, MD PhD, Shannon Kelley, MS, Erin Guest, MD, Michael J. Burke, MD, Sarah Wheelan, MD PhD, Patrick Brown, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 918.
https://doi.org/10.1182/blood-2018-99-119206
Published: 2018
Journal Articles

Genomic Analysis and Pathway Characterization of Genes with Somatic Variants in Infant Acute Lymphoblastic Leukemia

Jillian Fry, Midhat S. Farooqi, MD PhD, Byunggil Yoo, MS, Rumen Kostadinov, PhD, Emily Farrow, PhD CGC, Shannon Kelley, MS, Margaret Gibson, Neil Miller, Jeffrey Johnston, Patrick Brown, MD, Erin Guest, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3970.
https://doi.org/10.1182/blood.V130.Suppl_1.3970.3970
Published: 2017
Journal Articles

Landscape of Somatic Mutations and Gene Expression Changes in Relapsed Infant MLL-Rearranged Acute Lymphoblastic Leukemia

Rumen Kostadinov, PhD, Midhat Farooqi, MD PhD, Byunggil Yoo, MS, Emily Farrow, PhD CGC, Shannon Kelley, Margaret Gibson, Neil Miller, Erin M. Guest, MD, Patrick Brown, MD
Journal: Blood
Blood (2016) 128 (22): 1735.
https://doi.org/10.1182/blood.V128.22.1735.1735
Published: 2016
Journal Articles

Use of Dried Blood Spots for High through-Put, Rapid Turnaround Mutational Analysis in Patients with Hemophilia

Shannon L. Carpenter, MD MS, Emily Farrow, PhD, Lauren Amos, MD, Neil Miller, BA, Margaret Gibson, BA, Sara Streeter, Byunggil Yoo, PhD, Suzanne Herd, Sarah Soden, Stephen Kingsmore, M.B., Ch.B., B.A.O., D.Sc.
Journal: Blood
Blood (2014) 124 (21): 5034.
https://doi.org/10.1182/blood.V124.21.5034.5034
Published: 2014