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Journal Articles

Evidence-Based Risk Stratification of TP53 -Mutated Myeloid Neoplasms

Mithun V Shah, Kevin Hung, Anmol Baranwal, Zoe Price, Aref Al-Kali, Carla Toop, Patricia Greipp, Anna Brown, Dariusz Ladon, Dong Chen, Kebede Begna, Monika Kutyna, Danielle Rud, Mark R. Litzow, William J. Hogan, Peter Bardy, Talha Badar, Sharad Kumar, David T Yeung, Mrinal M. Patnaik, James M. Foran, Rong He, Naseema Gangat, Hamish S Scott, Cecilia Y. Arana Yi, Hassan B Alkhateeb, Abhishek A. Mangaonkar, Daniel Thomas, Christopher N. Hahn, Attilio Orazi, Daniel A. Arber, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase
Journal: Blood
Blood (2024) 144 (Supplement 1): 3213.
https://doi.org/10.1182/blood-2024-198269
Published: 2024
Journal Articles

Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53 -Mutations Using an Independent International Cohort

Mithun V Shah, Monika Kutyna, Syed Shah, Elizabeth Ngoc Hoa Tran, Anmol Baranwal, Dariusz Ladon, Aref Al-Kali, Anna Brown, Dong Chen, Patricia Greipp, Kebede Begna, Mark R. Litzow, William J. Hogan, Peter Bardy, Sharad Kumar, David T Yeung, Mrinal M. Patnaik, James M. Foran, Rong He, Naseema Gangat, Hamish S Scott, Cecilia Y. Arana Yi, Hassan Alkhateeb, Abhishek A Mangaonkar, Daniel Thomas, Christopher Norman Hahn, Attilio Orazi, Daniel A. Arber, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase
Journal: Blood
Blood (2023) 142 (Supplement 1): 3243.
https://doi.org/10.1182/blood-2023-187860
Published: 2023
Journal Articles

TP53 mutation in therapy-related myeloid neoplasm defines a distinct molecular subtype

Devendra Hiwase, Christopher Hahn, Elizabeth Ngoc Hoa Tran, Rakchha Chhetri, Anmol Baranwal, Aref Al-Kali, Kirsty Sharplin, Dariusz Ladon, Rachel Hollins, Patricia Greipp, Monika Kutyna, Hassan Alkhateeb, Talha Badar, Paul Wang, David M. Ross, Deepak Singhal, Naranie Shanmuganathan, Peter Bardy, Ashanka Beligaswatte, David Yeung, Mark R. Litzow, Abhishek Mangaonkar, Pratyush Giri, Cindy Lee, Angie Yong, Noemi Horvath, Nimit Singhal, Raghu Gowda, William Hogan, Naseema Gangat, Mrinal Patnaik, Kebede Begna, Ing S. Tiong, Andrew Wei, Sharad Kumar, Anna Brown, Hamish Scott, Daniel Thomas, Chung H. Kok, Ayalew Tefferi, Mithun Vinod Shah
Journal: Blood
Blood (2023) 141 (9): 1087–1091.
https://doi.org/10.1182/blood.2022018236
Published: 2023
Includes: Supplemental data
Journal Articles

Senolytic Therapy Can Reverse Senescent Bone Marrow Stroma of Therapy-Related Myeloid Neoplasm

Monika M Kutyna, Chung Hoow Kok, Yoon Lim, David Campbell, Sharon Paton, Chloe AL Thompson-Peach, Kelly SY Lim, Timothy Hughes, Sharad Kumar, Daniel Thomas, Stan Gronthos, Devendra Hiwase
Journal: Blood
Blood (2022) 140 (Supplement 1): 9755–9756.
https://doi.org/10.1182/blood-2022-167994
Published: 2022
Journal Articles

Integrated Personalized Prediction Model Identifies a Subgroup of Wild-Type TP53 therapy-Related Myeloid Neoplasm Patients with Poor Outcome

Mithun V. Shah, Christopher N Hahn, Rakchha Chhetri, Elizabeth Ngoc Hoa Tran, Deepak Singhal, William J. Hogan, Monika M Kutyna, Hassan B. Alkhateeb, Aref Al-Kali, Naseema Gangat, Mark R. Litzow, Begna Kebede, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Ayalew Tefferi, Anmol Baranwal, Naranie Shanmuganathan, Sharad Kumar, Daniel Thomas, Chung Hoow Kok, Devendra Hiwase
Journal: Blood
Blood (2022) 140 (Supplement 1): 6964–6965.
https://doi.org/10.1182/blood-2022-168349
Published: 2022
Journal Articles

Personalized Prediction Model to Risk Stratify Patients with Therapy-Related Myeloid Neoplasms

Chung Hoow Kok, Elizabeth Ngoc Hoa Tran, Dariusz Ladon, Rakchha Chhetri, Anmol Baranwal, Kirsty M Sharplin, Hassan B. Alkhateeb, Deepak Singhal, Aref Al-Kali, Naseema Gangat, David T Yeung, Mark R. Litzow, David M Ross, William J. Hogan, Ashanka Begna Kebede, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Ayalew Tefferi, Naranie Shanmuganathan, Sharad Kumar, Daniel Thomas, Mithun V. Shah, Devendra Hiwase
Journal: Blood
Blood (2022) 140 (Supplement 1): 6962–6963.
https://doi.org/10.1182/blood-2022-167978
Published: 2022
Journal Articles

TP53 Mutation Status Defines a Distinct Clinicopathological Entity of Therapy-Related Myeloid Neoplasm, Characterized By Genomic Instability and Extremely Poor Outcome

Mithun V. Shah, Christopher N Hahn, Elizabeth Ngoc Hoa Tran, Kirsty M Sharplin, Rakchha Chhetri, Anmol Baranwal, Monika M Kutyna, Paul Wang, Dariusz Ladon, Aref Al-Kali, Hassan B. Alkhateeb, David M Ross, David T Yeung, Naranie Shanmuganathan, Mark R. Litzow, Abhishek A. Mangaonkar, William J. Hogan, Naseema Gangat, Mrinal M.M. Patnaik, Begna Kebede, Sharad Kumar, Deepak Singhal, Anna L. Brown, Hamish S Scott, Daniel Thomas, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase
Journal: Blood
Blood (2022) 140 (Supplement 1): 9798–9799.
https://doi.org/10.1182/blood-2022-165859
Published: 2022
Journal Articles

Ndfip1 -deficient mice have impaired DMT1 regulation and iron homeostasis

Natalie J. Foot, Yew Ann Leong, Loretta E. Dorstyn, Hazel E. Dalton, Kristen Ho, Lin Zhao, Michael D. Garrick, Baoli Yang, Devendra Hiwase, Sharad Kumar
Journal: Blood
Blood (2011) 117 (2): 638–646.
https://doi.org/10.1182/blood-2010-07-295287
Published: 2011
Includes: Supplemental data
Journal Articles

Blocking of Cytokine Survival Signals along with Intense Bcr-Abl Kinase Inhibition May Eradicate CML Progenitor Cells.

Devendra K Hiwase, MD, Deborah L White, PhD, Jason A Powell, PhD, Verity A Saunders, Stephanie Zrim, Amity Frede, Mark Guthridge, Richard D'Andrea, PhD, L. Bik To, MD, Junia V. Melo, MD, PhD, Sharad Kumar, PhD, Timothy Hughes, MD
Journal: Blood
Blood (2009) 114 (22): 3250.
https://doi.org/10.1182/blood.V114.22.3250.3250
Published: 2009
Journal Articles

Short –Term Intense Bcr-Abl Kinase Inhibition Is Adequate to Trigger Cell Death in CML Cell Lines but Not in CML-CD34+ Cells Unless They Are Growth Factor Deprived.

Devendra K. Hi Wase, MD, Deborah L. White, PhD, Verity A. Saunders, Junia V. Melo, MD, PhD, Sharad Kumar, PhD, Timothy P. Hughes, MD
Journal: Blood
Blood (2008) 112 (11): 1086.
https://doi.org/10.1182/blood.V112.11.1086.1086
Published: 2008
Journal Articles

Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2

Natalie J. Foot, Hazel E. Dalton, Linda M. Shearwin-Whyatt, Loretta Dorstyn, Seong-Seng Tan, Baoli Yang, Sharad Kumar
Journal: Blood
Blood (2008) 112 (10): 4268–4275.
https://doi.org/10.1182/blood-2008-04-150953
Published: 2008
Includes: Supplemental data