1-11 of 11
Mira Patel
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Predictive Biomarker Analysis from the GBT021601 Survival Study in Townes Sickle Mice

Mira Patel Pochron, Jiaxin Sun, Alka A Potdar, Carsten Alt, Francis DeGuzman, Michael W. Connor, Brian Cathers, Kobina Dufu, David R Archer
Journal: Blood
Blood (2023) 142 (Supplement 1): 14.
https://doi.org/10.1182/blood-2023-177776
Published: 2023
Journal Articles

Preliminary Pharmacodynamic Results from a Multicenter Phase 2/3 Study of Next-Generation HbS Polymerization Inhibitor GBT021601 for the Treatment of Patients with Sickle Cell Disease

Mira Patel Pochron, Adeseye Michael Akinsete, Shehu Umar Abdullahi, Foluke A Fasola, Modupe Idowu, Sharon Pennington, William B Ershler, Marshall Patrick Stagg, Earl Fields, Morgan Sterling, Satheesh Chonat, Yuvika Paliwal, Karena Kong, David R Archer, Adeyemi Adenola, Eleanor A Lisbon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1155.
https://doi.org/10.1182/blood-2023-188929
Published: 2023
Journal Articles

Evaluation of GBT021601 As a Therapeutic Agent to Restore Bone Marrow Health and Effective Erythropoiesis in a Sickle Mouse Model

Britney Hernandez, Anupama Priyadarshini, Zachary Kostamo, Yankai Zhang, Ashwin P Patel, Michael A Pendergast, Madhulika Jupelli, Heli Huang, Annie Nguyen Dang, Mira Patel Pochron, Kobina Dufu, Vivien A Sheehan
Journal: Blood
Blood (2023) 142 (Supplement 1): 16.
https://doi.org/10.1182/blood-2023-175022
Published: 2023
Journal Articles

Preliminary Results from a Multicenter Phase 2/3 Study of Next-Generation HbS Polymerization Inhibitor GBT021601 for the Treatment of Patients with Sickle Cell Disease

Santosh L. Saraf, Shehu Umar Abdullahi, Adeseye Michael Akinsete, Foluke A Fasola, Modupe Idowu, Sharon Pennington, William B Ershler, Marshall Patrick Stagg, Wai Chin, Eric Zimmerman, Adeyemi Adenola, Mira Patel Pochron, Eleanor A Lisbon
Journal: Blood
Blood (2023) 142 (Supplement 1): 274.
https://doi.org/10.1182/blood-2023-177781
Published: 2023
Journal Articles

A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease

Clinical Trials & Observations
Jo Howard, Claire Jane Hemmaway, Paul Telfer, D. Mark Layton, John Porter, Moji Awogbade, Timothy Mant, Daniel D. Gretler, Kobina Dufu, Athiwat Hutchaleelaha, Mira Patel, Vincent Siu, Sandra Dixon, Noel Landsman, Margaret Tonda, Joshua Lehrer-Graiwer
Journal: Blood
Blood (2019) 133 (17): 1865–1875.
https://doi.org/10.1182/blood-2018-08-868893
Published: 2019
Journal Articles

GBT1118 Diminishes Vaso-Occlusion in Sickle Cell Disease Mice

Carsten Alt, PhD, Perry Liu, Chien-Ming Li, PhD, Abel Silva, Peter Rademacher, PhD, Hilary Zou, Mira Patel, PhD, Kobina Dufu, PhD, Donna Oksenberg, PhD, Katalin Kauser, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3516.
https://doi.org/10.1182/blood.V130.Suppl_1.3516.3516
Published: 2017
Journal Articles

Long-Term Dosing in Sickle Cell Disease Subjects with GBT440, a Novel HbS Polymerization Inhibitor

Josh Lehrer-Graiwer, MDMPhil, FACC, Jo Howard, MB, BChir, Claire Jane Hemmaway, MD, Moji Awogbade, Paul Telfer, FRCPath,MD, Mark Layton, MB, FRCP, John B. Porter, MD, Timothy Mant, MB, FFPM, FRCP, Kobina Dufu, PhD, Athiwat Hutchaleelaha, PhD, Donna Oksenberg, PhD, Mira Patel, PhD, Margaret Eleanor Tonda, PharmD, Kenneth Bridges, MD, Eleanor Ramos, MD
Journal: Blood
Blood (2016) 128 (22): 2488.
https://doi.org/10.1182/blood.V128.22.2488.2488
Published: 2016
Journal Articles

GBT440 Demonstrates High Specificity for Red Blood Cells in Nonclinical Species

Athiwat Hutchaleelaha, PhD, Mira Patel, PhD, Abel Silva, Donna Oksenberg, PhD, Brian Metcalf, PhD
Journal: Blood
Blood (2015) 126 (23): 2172.
https://doi.org/10.1182/blood.V126.23.2172.2172
Published: 2015
Journal Articles

GBT440, a Potent Anti-Sickling Hemoglobin Modifier Reduces Hemolysis, Improves Anemia and Nearly Eliminates Sickle Cells in Peripheral Blood of Patients with Sickle Cell Disease

Josh Lehrer-Graiwer, MDMPhil, FACC, Jo Howard, MD, Claire Jane Hemmaway, MD, Moji Awogbade, Paul Telfer, FRCPath,MD, Mark Layton, MB, FRCP, Timothy Mant, MB, FFPM, FRCP, Kobina Dufu, PhD, Athiwat Hutchaleelaha, PhD, Teri Koller, MBA, Donna Oksenberg, PhD, Mira Patel, PhD, Eleanor Ramos, MD
Journal: Blood
Blood (2015) 126 (23): 542.
https://doi.org/10.1182/blood.V126.23.542.542
Published: 2015
Journal Articles

GTx011, an Anti-Sickling Compound, Improves SS Blood Rheology By Reduction of HbS polymerization Via Allosteric Modulation of O 2 Affinity

Mira Patel, PhD, Pedro Cabrales, PhD, Kobina Dufu, PhD, Brian Metcalf, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2014) 124 (21): 1370.
https://doi.org/10.1182/blood.V124.21.1370.1370
Published: 2014
Journal Articles

GTx011, a Novel Agent That Improves Rheological Properties Of Sickle Cell Blood By Increasing Oxygen Affinity For Hemoglobin

Mira Patel, PhD, Donna Oksenberg, PhD, Abel Silva, BS, Andreas Betz, PhD, Brian Metcalf, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2013) 122 (21): 2207.
https://doi.org/10.1182/blood.V122.21.2207.2207
Published: 2013