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Journal Articles

DNA-Based Digital PCR for the Quantification of Residual Disease in CML — Sensitivity or Specificity?

Mary Alikian, Rebecca Ellwood, Olga Tatarinova, Graham David Rose, George Nteliopoulos, Gareth Gerrard, Jamshid S Khorashad, MD PhD, Dragana Milojkovic, MBBS, PhD, Alistair Reid, BSc, PhD, Letizia Foroni, MD PhD, Richard Clark, MBBS, MRCP, MRCPath, MD, Jane Apperley, MB ChB MD

Blood (2018) 132 (Supplement 1): 1738.

https://doi.org/10.1182/blood-2018-99-117616

Published: 2018

Journal Articles

Differential Expression of Genes Associated with Oncogene-Induced Senescence and Senescence Associated Secretory Phenotype in the Absence of Differential Expression of High Molecular Risk Genes and Genes Associated with JAK-STAT Pathway in Sorted Cells of Patients with Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Andrew Innes, Baoshan Ma, Gareth Gerrard, Zainul Abidin Norziha, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Jameela Sathar, Siew Fen Lye, Letizia Foroni, Tim Aitman, Liming Liang, Jesus Gil, Michael Laffan

Blood (2016) 128 (22): 4283.

https://doi.org/10.1182/blood.V128.22.4283.4283

Published: 2016

Journal Articles

Somatic Mutations in Epigenetic Modifiers Identified Using Next Generation Sequencing (NGS) in Diagnostic Samples of CML-CP Can Predict Poor Outcome on Imatinib Which Is Abrogated By Frontline 2G-TKI Therapy

Georgios Nteliopoulos, MSc, PhD, Alexandra Bazeos, MB, BS, MRCP, Gareth Gerrard, PhD, Simone Claudiani, MD, Ed Curry, PhD, Mary Alikian, MSc, PhD, Hui En Foong, Letizia Foroni, MD PhD FRCPath, Jane F. Apperley, MD

Blood (2016) 128 (22): 1223.

https://doi.org/10.1182/blood.V128.22.1223.1223

Published: 2016

Journal Articles

Assessment of Molecular Response in CML Patients with Atypical BCR-ABL Tanscripts. Recommendations By the EUTOS Collaboration

Thomas Ernst, MD, Vivien Schäfer, Helen E White, PhD, Susanne Saussele, MD, Thoralf Lange, MD, Gareth Gerrard, PhD, Nicholas CP Cross, PhD, Andreas Hochhaus, MD

Blood (2016) 128 (22): 1918.

https://doi.org/10.1182/blood.V128.22.1918.1918

Published: 2016

Journal Articles

Germline Calr exon 9 Variant and Somatic JAK2 V617F Mutation in a Patient with Polycythemia Vera Associated with Late Presentation and Severe Clinical Phenotype

Chieh Lee Wong, Gareth Gerrard, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Jameela Sathar, Liming Liang, Tim Aitman, Letizia Foroni, Michael Laffan

Blood (2016) 128 (22): 5485.

https://doi.org/10.1182/blood.V128.22.5485.5485

Published: 2016

Journal Articles

Gene Expression Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Baoshan Ma, Gareth Gerrard, Martyna Adamowicz-Brice, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Gin Gin Gan, Jameela Sathar, Siew Fen Lye, Letizia Foroni, Tim Aitman, Liming Liang, Michael Laffan

Blood (2015) 126 (23): 5201.

https://doi.org/10.1182/blood.V126.23.5201.5201

Published: 2015

Journal Articles

DNA Methylation Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Baoshan Ma, Martyna Adamowicz-Brice, Gareth Gerrard, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Gin Gin Gan, Jameela Sathar, Letizia Foroni, Tim Aitman, Liming Liang, Michael Laffan

Blood (2015) 126 (23): 5204.

https://doi.org/10.1182/blood.V126.23.5204.5204

Published: 2015

Journal Articles

Targeted Sequencing of Sorted Peripheral Blood Cells Reveals Novel Germline and Somatic Variants in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

Chieh Lee Wong, Gareth Gerrard, Martyna Adamowicz-Brice, Zainul Abidin Norziha, Nor Rafeah Tumian, Soon Keng Cheong, Chooi Fun Leong, Ping Chong Bee, Gin Gin Gan, Jameela Sathar, Baoshan Ma, Liming Liang, Tim Aitman, Letizia Foroni, Michael Laffan

Blood (2015) 126 (23): 5213.

https://doi.org/10.1182/blood.V126.23.5213.5213

Published: 2015

Journal Articles

Excellent Outcome and Good Tolerability of Long-Term Imatinib in Patients with Chronic Myeloid Leukemia (CML)

Simone Claudiani, Nikhita Gupta, BSc, Ji Soo Baik, BSc, Simona Deplano, MDPhD, Renuka Palanicawander, Gareth Gerrard, Alistair G Reid, BSc, PhD, Richard M Szydlo, BSc, PhD, Dragana Milojkovic, Letizia Foroni, Jane F. Apperley, MD

Blood (2015) 126 (23): 2794.

https://doi.org/10.1182/blood.V126.23.2794.2794

Published: 2015

Journal Articles

Elucidation of the EP defect in Diamond-Blackfan anemia by characterization and prospective isolation of human EPs

Deena Iskander, Bethan Psaila, Gareth Gerrard, Aristeidis Chaidos, Hui En Foong, Yvonne Harrington, Leena C. Karnik, Irene Roberts, Josu de la Fuente, Anastasios Karadimitris

Blood (2015) 125 (16): 2553–2557.

https://doi.org/10.1182/blood-2014-10-608042

Published: 2015

Includes: Supplemental data

Journal Articles

Prognostic Value of Multi-Drug Resistance 1 Gene (MDR1) Expression in Newly Diagnosed Patients with Chronic Myeloid Leukemia on Nilotinib Treatment—a Subanalysis of the ENEST1st Study

Christian Dietz, PhD, Michael Lauseker, PhD, Benjamin Hanfstein, MD, Philippe Rousselot, MD, Thoralf Lange, MD, Jacqueline Maier, PhD, Letizia Foroni, Gareth Gerrard, Rodica Talmaci, PhD, Jeroen JWM Janssen, MD, Oliver Frank, PhD, Susanne Saussele, MD, Frank Giles, MDMB, Andreas Hochhaus, MD, Martin C. Müller, MD

Blood (2014) 124 (21): 3144.

https://doi.org/10.1182/blood.V124.21.3144.3144

Published: 2014

Journal Articles

Incidence of Vascular Thrombotic Events in 183 Consecutive Patients Treated with Nilotinib: A Single Centre Experience

James Gilbert, BSc, Simona Deplano, Richard Szydlo, BSc PhD, Renuka Palanicawandar, MD, Gareth Gerrard, Letizia Foroni, Jane F. Apperley, MD, Dragana Milojkovic

Blood (2014) 124 (21): 3147.

https://doi.org/10.1182/blood.V124.21.3147.3147

Published: 2014

Journal Articles

Clinical Outcome Following Change of Tyrosine Kinase Inhibitor (TKI) According to the Detection of an ABL Kinase Mutation

Renuka Palani, Richard M Szydlo, Jane F. Apperley, Gareth Gerrard, Chrissy Giles, Simona Deplano, Alistair Reid, Letizia Foroni, Dragana Milojkovic

Blood (2014) 124 (21): 4557.

https://doi.org/10.1182/blood.V124.21.4557.4557

Published: 2014

Journal Articles

UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia

Adele K. Fielding, Jacob M. Rowe, Georgina Buck, Letizia Foroni, Gareth Gerrard, Mark R. Litzow, Hillard Lazarus, Selina M. Luger, David I. Marks, Andrew K. McMillan, Anthony V. Moorman, Bella Patel, Elisabeth Paietta, Martin S. Tallman, Anthony H. Goldstone

Blood (2014) 123 (6): 843–850.

https://doi.org/10.1182/blood-2013-09-529008

Published: 2014

Includes: Supplemental data

Journal Articles

NGS-Assisted DNA-Based Digital qPCR Facilitates Stratification Of CML Patients In Long-Term Molecular Remission Based On The Presence Of Detectable BCR-ABL1 DNA

Mary Alikian, Peter Ellery, Matrin Forbes, Gareth Gerrard, PhD, Tim Aitman, Dalia Kasperaviciute, Dragana Milojkovic, PhD, David Marin, MD, John M Goldman, MD, Jane F Apperley, MD, Letizia Foroni, MD, Alistair Reid, PhD

Blood (2013) 122 (21): 4006.

https://doi.org/10.1182/blood.V122.21.4006.4006

Published: 2013

Journal Articles

Targeted High-Throughput Sequencing For The Detection Of Mutations Associated With Myeloproliferative Neoplasms

Ferrari Robin, BSc, Sakuntala Ale, Aysha Patel, BSc, Mikel Valgañón, PhD, Hui En Foong, MSc, Mary Alikian, Kikkeri Naresh, Dragana Milojkovic, PhD, Jane F Apperley, MD, Letizia Foroni, MD, Gareth Gerrard, PhD

Blood (2013) 122 (21): 1613.

https://doi.org/10.1182/blood.V122.21.1613.1613

Published: 2013

Journal Articles

The Depth Of ‘Complete’ Molecular Response Predicts Molecular Relapse In Chronic Myeloid Leukaemia Patients On Tyrosine Kinase Inhibitor Therapy

Heledd Thomas, BSc, Jane F Apperley, MD, Richard M Szydlo, PhD, Gareth Gerrard, PhD, David Marin, MD, Dragana Milojkovic, PhD, Letizia Foroni, MD

Blood (2013) 122 (21): 5201.

https://doi.org/10.1182/blood.V122.21.5201.5201

Published: 2013

Journal Articles

Dose Interruption/Reduction Of Tyrosine Kinase Inhibitors In The First 3 Months Of Treatment of CML Is Associated With Inferior Early Molecular Responses and Predicts For An Increased Likelihood Of Discontinuation Of The 1st Line Agent

Jane F Apperley, MD, Richard M Szydlo, PhD, Gareth Gerrard, PhD, James R McCue, Jamie Wardle, Richard E Clark, MD, Stephen G O'Brien, Letizia Foroni, MD

Blood (2013) 122 (21): 93.

https://doi.org/10.1182/blood.V122.21.93.93

Published: 2013

Journal Articles

Combining BCR-ABL1 transcript levels at 3 and 6 months in chronic myeloid leukemia: implications for early intervention strategies

Pratap Neelakantan, Gareth Gerrard, Claire Lucas, Dragana Milojkovic, Philippa May, Lihui Wang, Christos Paliompeis, Marco Bua, Alistair Reid, Katayoun Rezvani, Stephen O'Brien, Richard Clark, John Goldman, David Marin

Blood (2013) 121 (14): 2739–2742.

https://doi.org/10.1182/blood-2012-11-466037

Published: 2013

Includes: Supplemental data

Journal Articles

A Novel Splice Site Variant of hOCT-1 and Response to Imatinib.

Jacob Grinfeld, Juan M Alonso-Dominguez, Mary Alikian, Mikel Valgañón, PhD, Georgios Nteliopoulos, PhD, Deborah L. White, PhD, FFSc(RCPA), David Marin, Corinne Hedgley, Stephen O'Brien, Richard E. Clark, MD, Richard M Szydlo, Jane Apperley, John M Goldman, MD, Letizia Foroni, Gareth Gerrard, PhD

Blood (2012) 120 (21): 2555.

https://doi.org/10.1182/blood.V120.21.2555.2555

Published: 2012

NARROW

DNA-Based Digital PCR for the Quantification of Residual Disease in CML — Sensitivity or Specificity?

Somatic Mutations in Epigenetic Modifiers Identified Using Next Generation Sequencing (NGS) in Diagnostic Samples of CML-CP Can Predict Poor Outcome on Imatinib Which Is Abrogated By Frontline 2G-TKI Therapy

Assessment of Molecular Response in CML Patients with Atypical BCR-ABL Tanscripts. Recommendations By the EUTOS Collaboration

Germline Calr exon 9 Variant and Somatic JAK2 V617F Mutation in a Patient with Polycythemia Vera Associated with Late Presentation and Severe Clinical Phenotype

Gene Expression Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Polycythemia Vera and Primary Myelofibrosis

DNA Methylation Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

Targeted Sequencing of Sorted Peripheral Blood Cells Reveals Novel Germline and Somatic Variants in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocythemia, Polycythemia Vera and Primary Myelofibrosis

Excellent Outcome and Good Tolerability of Long-Term Imatinib in Patients with Chronic Myeloid Leukemia (CML)

Elucidation of the EP defect in Diamond-Blackfan anemia by characterization and prospective isolation of human EPs

Prognostic Value of Multi-Drug Resistance 1 Gene (MDR1) Expression in Newly Diagnosed Patients with Chronic Myeloid Leukemia on Nilotinib Treatment—a Subanalysis of the ENEST1st Study

Incidence of Vascular Thrombotic Events in 183 Consecutive Patients Treated with Nilotinib: A Single Centre Experience

Clinical Outcome Following Change of Tyrosine Kinase Inhibitor (TKI) According to the Detection of an ABL Kinase Mutation

UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia

NGS-Assisted DNA-Based Digital qPCR Facilitates Stratification Of CML Patients In Long-Term Molecular Remission Based On The Presence Of Detectable BCR-ABL1 DNA

Targeted High-Throughput Sequencing For The Detection Of Mutations Associated With Myeloproliferative Neoplasms

The Depth Of ‘Complete’ Molecular Response Predicts Molecular Relapse In Chronic Myeloid Leukaemia Patients On Tyrosine Kinase Inhibitor Therapy

Dose Interruption/Reduction Of Tyrosine Kinase Inhibitors In The First 3 Months Of Treatment of CML Is Associated With Inferior Early Molecular Responses and Predicts For An Increased Likelihood Of Discontinuation Of The 1st Line Agent

Combining BCR-ABL1 transcript levels at 3 and 6 months in chronic myeloid leukemia: implications for early intervention strategies

A Novel Splice Site Variant of hOCT-1 and Response to Imatinib.

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American Society of Hematology

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American Society of Hematology

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