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David A. Irvine
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Journal Articles

A UK Intention to Treat Analysis of Brexucabtagene Autoleucel for Relapsed or Refractory Adult Acute Lymphoblastic Leukaemia Following 1 Year of Therapy Access

Anna Z Castleton, Michelle Lannon, Ned Atiyah, Alexandra Smith, Lindsay George, Sridhar Chaganti, Eleni Tholouli, Pakhshan Farshi, Nicholas Cunningham, Claire Arnold, Nick Morley, Philippa Kelsey, Prudence Hardefeldt, Katja Kimberger, Manish Jain, Maeve O'Reilly, Richard Burt, Tobias Menne, Ahmed Abdulgawad, Katharine Hodby, Aniruddha Dayama, David A. Irvine, Anne Louise Latif, Deborah Susan Richardson, Mariam Amer, Ram Malladi, James Aries, Seda Cakmak, Johannes De Vos, Gerardo Errico, Emma Nicholson, Kirsty Marie Sharplin, Andrew Peniket, Bela Patel Wrench, Anthony Moorman, Clare Rowntree, David Marks, Adele Fielding, Deborah Yallop
Journal: Blood
Blood (2024) 144 (Supplement 1): 2823.
https://doi.org/10.1182/blood-2024-199287
Published: 2024
Journal Articles

Safety, Efficiency and Long-Term Follow-up of AUTO1, a Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Claire Roddie, Juliana Dias Alves Pinto, Maeve A O'Reilly, Marina Mitsikakou, Eftychia Charalambous, Louisa Green, Mhairi Vaughan, Giulia Agliardi, John Garcia, Evie Lewin, Mark W. Lowdell, Maria A V Marzolini, Leigh Wood, Helen Holmes, Yenting Ngai, Bilyana Popova, William Wilson, Sangeetha Kunaseelan, Victoria Spanswick, Helen Lowe, Leah Ensell, John A. Hartley, Simon Morley, David C. Linch, Adrian Bloor, David A. Irvine, Martin Pule, Karl S Peggs
Journal: Blood
Blood (2022) 140 (Supplement 1): 7452–7453.
https://doi.org/10.1182/blood-2022-167053
Published: 2022
Journal Articles

First in Human Study of AUTO4, a TRBC1-Targeting CAR T-Cell Therapy in Relapsed/Refractory TRBC1-Positive Peripheral T-Cell Lymphoma

Kate Cwynarski, Gloria Iacoboni, Eleni Tholouli, Tobias F. Menne, David A. Irvine, Nivetha Balasubramaniam, Leigh Wood, Justin Shang, Yiyun Zhang, Silvia Basilico, Birgit Huber, Mary Vinson, Koki Lilova, Wolfram Brugger, Martin Pule
Journal: Blood
Blood (2022) 140 (Supplement 1): 10316–10317.
https://doi.org/10.1182/blood-2022-165971
Published: 2022
Journal Articles

Real-World Data of High-Grade Lymphoma Patients Treated with CD19 CAR-T in England

Andrea Kuhnl, Claire Roddie, PhD MD, Nuria Martinez-Cibrian, Tobias F Menne, MD PhD FRCPath, Kim Linton, MBChB PhD, Sanne Lugthart, Sridhar Chaganti, MDPhDMRCP,FRCPath, Robin Sanderson, MRCP,FRCPath, Maria A V Marzolini, Jane Norman, MD, Wendy Osborne, MD, John Radford, Stephen Robinson, MBBS, PhD BSc, Ram Malladi, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Maeve A O'Reilly, MBBCHBAO, Muhammad Saif, MD, Geoff Shenton, Adrian Bloor, FRCPath, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David A. Irvine, BSc, MBBChir, MRCP, FRCPath, PhD, Orla Stewart, Arzhang Ardavan, Kate Robinson, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Kristian M Bowles, MBBS, PhD, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Rod Johnson, Andrew K McMillan, FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 767.
https://doi.org/10.1182/blood-2019-124177
Published: 2019
Journal Articles

CD93 Is a Novel Biomarker of Leukemia Stem Cells in Chronic Myeloid Leukemia

Ross Kinstrie, PhD BSc, Gillian A. Horne, BSc hons, MBChB, MRCP, MRES, Heather Morrison, BSc hons, Hothri A. Moka, BSc hons, Jennifer Cassels, BSc hons, Karen Dunn, BSc hons, Pawel Herzyk, MSc, PhD, David A. Irvine, BSc, MBBChir, MRCP, FRCPath, PhD, Mhairi Copland, BSc (Hons) MB ChB PhDFRCP FRCPath
Journal: Blood
Blood (2015) 126 (23): 49.
https://doi.org/10.1182/blood.V126.23.49.49
Published: 2015
Journal Articles

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

Kimberly Cramer-Morales, Margaret Nieborowska-Skorska, Kara Scheibner, Michelle Padget, David A. Irvine, Tomasz Sliwinski, Kimberly Haas, Jaewoong Lee, Huimin Geng, Darshan Roy, Artur Slupianek, Feyruz V. Rassool, Mariusz A. Wasik, Wayne Childers, Mhairi Copland, Markus Müschen, Curt I. Civin, Tomasz Skorski
Journal: Blood
Blood (2013) 122 (7): 1293–1304.
https://doi.org/10.1182/blood-2013-05-501072
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

Targeting hedgehog in hematologic malignancy

David A. Irvine, Mhairi Copland
Journal: Blood
Blood (2012) 119 (10): 2196–2204.
https://doi.org/10.1182/blood-2011-10-383752
Published: 2012
Journal Articles

Combination of the Hedgehog Pathway Inhibitor LDE225 and Nilotinib Eliminates Chronic Myeloid Leukemia Stem and Progenitor Cells.

David A Irvine, roMB, ChB, Bin Zhang, MD, PhD, Elaine K Allan, BSc, Tessa L Holyoake, PhD, MB, ChB, FRCP, FRCPath, FRSE, Marion Dorsch, PhD, Paul W Manley, PhD, Ravi Bhatia, MD, PhD, Mhairi Copland, PhD, BSc, MB, ChB, MRCP, FRCPath
Journal: Blood
Blood (2009) 114 (22): 1428.
https://doi.org/10.1182/blood.V114.22.1428.1428
Published: 2009
Journal Articles

Induction Therapy with High-Dose Dex Alone in Newly Diagnosed Myeloma Patients Produces a 57% Partial Response and Is Predictive of Progression Free Survival.

David A. Irvine, Michael J. Barnett, Ryan Brinkman, Donna L. Forrest, Donna E. Hogge, Julye Lavoie, Linda Lei, Stephen H. Nantel, Thomas J. Nevill, Janet Nitta, John Shepherd, Kevin Song, Cynthia Toze, Heather Sutherland
Journal: Blood
Blood (2006) 108 (11): 3098.
https://doi.org/10.1182/blood.V108.11.3098.3098
Published: 2006