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Journal Articles

Matched donor allogeneic CAR-T for adult B-ALL: toxicity, efficacy, repeat dosing, and the importance of lymphodepletion

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Clinical Trials & Observations
Claire Roddie, Juliana Dias, Maeve A. O’Reilly, Mahnaz Abbasian, Amaia Cadinanos-Garai, Ketki Vispute, Leticia Bosshard-Carter, Marina Mitsikakou, Eftychia Charalambous, Vedika Mehra, Harriet Roddy, Gordon Weng-Kit Cheung, John A. Hartley, Nasir Mahmoud, Leah Ensell, Yashma Patel, Maria A. V. Marzolini, Farzin Farzaneh, Lauren Nickolay, Nourredine Himoudi, Farhatullah Syed, Bilyana Popova, Sevasti Galani, Alexander Day, Mark W. Lowdell, Karl S. Peggs
Journal: Blood
Blood (2025) 146 (14): 1664–1676.
https://doi.org/10.1182/blood.2025028790
Published: 2025
Includes: Supplemental data
Journal Articles

Non-Western Real-World Experience of Axi-Cel CAR-T in Refractory/Relapsed B-Cell Lymphoma from a Tertiary Center in Saudi Arabia

Free
Khalid Alsuhaibani, Amal Hejab, Syed Osman Ahmed, Ali Alahmari, Amr Hanbali, Walid Rasheed, Alfadel Alshaibani, Naeem A. Chaudhri, Ayman Saad, Shaykhah Alotaibi, Hanan Alkhaldi, Abdullah Alamer, Mansour Alfayez, Saud Alhayli, Marwan Shaheen, Feras Abdulaziz Alfraih, Ahmad S. Alotaibi, Hadeel Samarkandi, Farhatullah Syed, Fahad Alsharif, Fahad Almohareb, Hazza Alzahrani, Mahmoud Aljurf, Riad Elfakih, Abdulwahab Albabtain
Journal: Blood
Blood (2024) 144 (Supplement 1): 7824.
https://doi.org/10.1182/blood-2024-203769
Published: 2024
Journal Articles

Favorable Outcomes with Bridging Radiation Therapy Prior to Anti-CD19 Chimeric Antigen Receptor T-Cell CART in B Cell Lymphoma, a Report from Saudi Arabia

Free
Amal Hejab, Khalid Alsuhaibani, Syed Osman Ahmed, Yasser Khafaga, Mohamed Alshabanah, Ali Alahmari, Amr Hanbali, Walid Rasheed, Alfadel Alshaibani, Naeem A. Chaudhri, Ayman Saad, Shaykhah Alotaibi, Hanan Alkhaldi, Abdullah Alamer, Mansour Alfayez, Saud Alhayli, Hadeel H Samarkandi, Tusneem Ahmed M Elhassan, Farhatullah Syed, Marwan Shaheen, Feras Abdulaziz Alfraih, Ahmad S. Alotaibi, Fahad Alsharif, Fahad Almohareb, Hazza A. Alzahrani, Mahmoud Aljurf, Riad Elfakih, Abdulwahab Albabtain
Journal: Blood
Blood (2024) 144 (Supplement 1): 7754.
https://doi.org/10.1182/blood-2024-202399
Published: 2024
Journal Articles

Tvt CAR7: Phase 1 Clinical Trial of Base-Edited "Universal” CAR7 T Cells for Paediatric Relapsed/Refractory T-ALL

Free
Robert Chiesa, Christos Georgiadis, Giorgio Ottaviano, Farhatullah Syed, Toni Braybrook, Annie Etuk, Hong Zhan, Soragia Athina Gkazi, Roland Preece, Stuart Adams, Rebecca Thomas, Arnold Awuah, Kimberly Gilmour, Lana Mhaldien, Jan Chu, Danielle Pinner, Agnieszka Kubat, Paul Veys, Kanchan Rao, Giovanna Lucchini, David O'Connor, Ajay Vora, Waseem Qasim
Journal: Blood
Blood (2022) 140 (Supplement 1): 4579–4580.
https://doi.org/10.1182/blood-2022-169114
Published: 2022
Journal Articles

Single and Combinational Multiplex Base-Edited 'Universal' CAR T Cells in a Humanised Model of Primary CD7+CD33+ AML

Free
Arnold Kloos, Christos Georgiadis, Annie Etuk, Soragia Athina Gkazi, Farhatullah Syed, Toni Braybrook, Hong Zhan, Renuka Kadirkamanathan, Nadine Kattre, Kerstin Görlich, Thomas Fangmann, Axel Schambach, Martin G. Sauer, Michael Heuser, Waseem Qasim
Journal: Blood
Blood (2022) 140 (Supplement 1): 7425–7426.
https://doi.org/10.1182/blood-2022-168719
Published: 2022
Journal Articles

TT52CAR19: Phase 1 Trial of CRISPR/Cas9 Edited Allogeneic CAR19 T Cells for Paediatric Relapsed/Refractory B-ALL

Free
Giorgio Ottaviano, Christos Georgiadis, Farhatullah Syed, Soragia Athina Gkazi, Hong Zhan, Annie Etuk, Jan Chu, Danielle Pinner, Sarah Inglott, Kimberly Gilmour, Stuart Adams, Susanne Kricke, Natalia Izotova, Dariusz Ladon, Agnieszka Kubat, Paul Veys, Ajay Vora, Kanchan Rao, Waseem Qasim
Journal: Blood
Blood (2021) 138 (Supplement 1): 4838.
https://doi.org/10.1182/blood-2021-152426
Published: 2021
Journal Articles

ALLCAR19: Updated Data Using AUTO1, a Novel Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Free
Claire Roddie, PhD MD, Maeve A O'Reilly, MBBCHBAO, Maria A V Marzolini, Leigh Wood, BA, Juliana Dias, Amaia Cadinanos Garai, BSc MSc, Leticia Bosshard, Mahnaz Abbasian, Mark W. Lowdell, BSc, MSc, PhD FRCPath, Graham Wheeler, Joanna Olejnik, Bilyana Popova, MSc, Laura Clifton-Hadley, PhDBSc, Yashma Pathak, Victoria Spanswick, Helen Lowe, John A. Hartley, PhD, Farhatullah Syed, Waseem Qasim, MBBS, PhD, Farzin Farzaneh, PhD, David C. Linch, Martin Pule, MDPhD, Karl S Peggs, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-137768
Published: 2020
Journal Articles

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1

Free
Clinical Trials & Observations
Julien Record, Dessislava Malinova, Helen L. Zenner, Vincent Plagnol, Karolin Nowak, Farhatullah Syed, Gerben Bouma, James Curtis, Kimberly Gilmour, Catherine Cale, Scott Hackett, Guillaume Charras, Dale Moulding, Sergey Nejentsev, Adrian J. Thrasher, Siobhan O. Burns
Journal: Blood
Blood (2015) 126 (13): 1527–1535.
https://doi.org/10.1182/blood-2014-12-611012
Published: 2015
Includes: Multimedia, Supplemental data