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Journal Articles

Tvt CAR7: Phase 1 Clinical Trial of Base-Edited "Universal” CAR7 T Cells for Paediatric Relapsed/Refractory T-ALL

Robert Chiesa, Christos Georgiadis, Giorgio Ottaviano, Farhatullah Syed, Toni Braybrook, Annie Etuk, Hong Zhan, Soragia Athina Gkazi, Roland Preece, Stuart Adams, Rebecca Thomas, Arnold Awuah, Kimberly Gilmour, Lana Mhaldien, Jan Chu, Danielle Pinner, Agnieszka Kubat, Paul Veys, Kanchan Rao, Giovanna Lucchini, David O'Connor, Ajay Vora, Waseem Qasim
Journal: Blood
Blood (2022) 140 (Supplement 1): 4579–4580.
https://doi.org/10.1182/blood-2022-169114
Published: 2022
Journal Articles

Single and Combinational Multiplex Base-Edited 'Universal' CAR T Cells in a Humanised Model of Primary CD7+CD33+ AML

Arnold Kloos, Christos Georgiadis, Annie Etuk, Soragia Athina Gkazi, Farhatullah Syed, Toni Braybrook, Hong Zhan, Renuka Kadirkamanathan, Nadine Kattre, Kerstin Görlich, Thomas Fangmann, Axel Schambach, Martin G. Sauer, Michael Heuser, Waseem Qasim
Journal: Blood
Blood (2022) 140 (Supplement 1): 7425–7426.
https://doi.org/10.1182/blood-2022-168719
Published: 2022
Journal Articles

TT52CAR19: Phase 1 Trial of CRISPR/Cas9 Edited Allogeneic CAR19 T Cells for Paediatric Relapsed/Refractory B-ALL

Giorgio Ottaviano, Christos Georgiadis, Farhatullah Syed, Soragia Athina Gkazi, Hong Zhan, Annie Etuk, Jan Chu, Danielle Pinner, Sarah Inglott, Kimberly Gilmour, Stuart Adams, Susanne Kricke, Natalia Izotova, Dariusz Ladon, Agnieszka Kubat, Paul Veys, Ajay Vora, Kanchan Rao, Waseem Qasim
Journal: Blood
Blood (2021) 138 (Supplement 1): 4838.
https://doi.org/10.1182/blood-2021-152426
Published: 2021
Journal Articles

A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation

Emma C Morris, Rita Tendeiro-Rego, Rachel Richardson, MSc, Thomas A Fox, BSc, MSc, MRCP, Francesca Sillito, BSc, MRCP, FRCPath, Angelika Holler, Sharyn Thomas, Shao-An Xue, Irma Alicia Martínez-Dávila, Emma Nicholson, Mandana Ahmadi, Judith King, Panagiotis Kottaridis, Ronjon Chakraverty, BMBS, PhD, Kirsty Thomson, Stephen Robinson, MBBS, PhD BSc, Andres E. Virchis, FRCP, FRCPath, Asim Khwaja, Michelle Quaye, Hong Zhan, Waseem Qasim, MBBS, PhD, Nourredine Himoudi, Jacqueline Barry, Natalie Mount, PhD, Terri Gaskell, Michaela Sharpe, Shannon M Inman, Kurt C. Gunter, MD, Hans Stauss
Journal: Blood
Blood (2019) 134 (Supplement_1): 1367.
https://doi.org/10.1182/blood-2019-128044
Published: 2019
Journal Articles

A Novel Second Generation CD19 CAR for Therapy of High Risk/Relapsed Paediatric CD19 + Acute Lymphoblastic Leukaemia and Other Haematological Malignancies: Preliminary Results from the Carpall Study

Sara Ghorashian, MD PhD FRCPath, Anne Marijn Kramer, MD, Sarah Jayne Albon, BSc, MSc, Catherine Irving, BSc, Lucas Chan, PhD, Fernanda Castro, PhD, Bilyana Popova, Kim Champion, PhD, Gary Wright, Hong Zhan, PhD, Waseem Qasim, MBBS PhD, Robert Wynn, Rachael Hough, MD BMBS, FRCP, FRCPath, Farzin Farzaneh, Martin A Pule, MD PhD, Persis J Amrolia, Professor
Journal: Blood
Blood (2016) 128 (22): 4026.
https://doi.org/10.1182/blood.V128.22.4026.4026
Published: 2016
Journal Articles

Automated Lentiviral Transduction of T Cells with Cars Using the Clinimacs Prodigy

Ulrike Mock*, PhD, Lauren Nickolay*, PhD, Gordon Weng-Kit Cheung, Hong Zhan, PhD, Karl Peggs, MBBChir, MRCP, FRCPath, Ian CD Johnston, PhD, Andrew Kaiser, PhD, Martin Pule, PhD, Adrian Thrasher, MD PhD, Waseem Qasim, MBBS PhD
Journal: Blood
Blood (2015) 126 (23): 2043.
https://doi.org/10.1182/blood.V126.23.2043.2043
Published: 2015
Journal Articles

First Clinical Application of Talen Engineered Universal CAR19 T Cells in B-ALL

Waseem Qasim, MBBS PhD, Persis Jal Amrolia, Sujith Samarasinghe, MD PhD, Sara Ghorashian, MD PhD FRCPath, Hong Zhan, PhD, Sian Stafford, PhD, Katie Butler, PhD, Gul Ahsan, Kimberly Gilmour, Stuart Adams, PhD, Danielle Pinner, Robert Chiesa, Steve Chatters, PhD, Sue Swift, PhD, Nicholas Goulden, MD PhD, Karl Peggs, MBBChir, MRCP, FRCPath, Adrian J Thrasher, MD PhD, Paul Veys, Martin Pule, PhD
Journal: Blood
Blood (2015) 126 (23): 2046.
https://doi.org/10.1182/blood.V126.23.2046.2046
Published: 2015
Journal Articles

Multiplex Genome Editing As a Platform for “Off-the-Shelf” Adoptive CAR T-Cell Immunotherapies

Sophie Derniame, Hong Zhan, Laurent Poirot, Cecile Schiffer-Mannioui, Roman Galetto, Marine Beurdeley, Stephan Reynier, Sylvain Arnould, Waseem Qasim, Julianne Smith
Journal: Blood
Blood (2014) 124 (21): 1111.
https://doi.org/10.1182/blood.V124.21.1111.1111
Published: 2014