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Shao-An Xue
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Journal Articles

A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation

Emma C Morris, Rita Tendeiro-Rego, Rachel Richardson, MSc, Thomas A Fox, BSc, MSc, MRCP, Francesca Sillito, BSc, MRCP, FRCPath, Angelika Holler, Sharyn Thomas, Shao-An Xue, Irma Alicia Martínez-Dávila, Emma Nicholson, Mandana Ahmadi, Judith King, Panagiotis Kottaridis, Ronjon Chakraverty, BMBS, PhD, Kirsty Thomson, Stephen Robinson, MBBS, PhD BSc, Andres E. Virchis, FRCP, FRCPath, Asim Khwaja, Michelle Quaye, Hong Zhan, Waseem Qasim, MBBS, PhD, Nourredine Himoudi, Jacqueline Barry, Natalie Mount, PhD, Terri Gaskell, Michaela Sharpe, Shannon M Inman, Kurt C. Gunter, MD, Hans Stauss
Journal: Blood
Blood (2019) 134 (Supplement_1): 1367.
https://doi.org/10.1182/blood-2019-128044
Published: 2019
Journal Articles

Endogenous T Cell Receptors Drive Non-Specific Suppression by Foxp3 MHC Class I-Restricted T Cell Receptor-Transduced Polyclonal CD4+ T Cells in Models of Graft-Versus-Host Disease.

Benjamin J Uttenthal, MD, Emma Nicholson, MD, Ben Carpenter, MD, Sara Ghorashian, MD, Graham P Wright, PhD, Barry R Flutter, PhD, Shao-An Xue, PhD, Ronjon Chakraverty, MD, PhD, Emma Morris, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3152.
https://doi.org/10.1182/blood.V120.21.3152.3152
Published: 2012
Journal Articles

Enhancing the Efficacy of T Cell Receptor (TCR) Gene Therapy by Co-Transfer of TCR and Additional CD3 Molecules Into CD4+ T Cells

Emma K Nicholson, MD, Maryam Ahmadi, PhD, Angelika Holler, Rebecca Pike, PhD, Ben Carpenter, MD, Sharyn Thomas, PhD, Sara Ghorashian, MD, Shao-An Xue, PhD, Hans Stauss, MD, PhD, Emma Morris, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2044.
https://doi.org/10.1182/blood.V120.21.2044.2044
Published: 2012
Journal Articles

In Vivo Selection of Mycophenolate Mofetil-Resistant T Cells for Adoptive Immunotherapy.

James Edward Griffin, MD, Ben Carpenter, MD, Emma Nicholson, MD, Shao-an Xue, PhD, Martin Pule, MD, Hans Stauss, MD, PhD, Ronjon Chakraverty, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3008.
https://doi.org/10.1182/blood.V120.21.3008.3008
Published: 2012
Journal Articles

CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens

Sara Ghorashian, MD, Ben Carpenter, MD, Angelika Holler, Emma Nicholson, MD, Maryam Ahmadi, PhD, Mathias Zech, MD, Clare Bennett, PhD, Shao-An Xue, PhD, Emma Morris, MD, PhD, Hans Stauss, MD, PhD, Ronjon Chakraverty, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 952.
https://doi.org/10.1182/blood.V120.21.952.952
Published: 2012
Journal Articles

CD3 limits the efficacy of TCR gene therapy in vivo

Maryam Ahmadi, Judith W. King, Shao-An Xue, Cécile Voisine, Angelika Holler, Graham P. Wright, Jonathan Waxman, Emma Morris, Hans J. Stauss
Journal: Blood
Blood (2011) 118 (13): 3528–3537.
https://doi.org/10.1182/blood-2011-04-346338
Published: 2011
Journal Articles

Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen

Sharyn Thomas, Shao-An Xue, Charles R. M. Bangham, Bent K. Jakobsen, Emma C. Morris, Hans J. Stauss
Journal: Blood
Blood (2011) 118 (2): 319–329.
https://doi.org/10.1182/blood-2010-12-326736
Published: 2011
Journal Articles

Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination

Constandina Pospori, Shao-An Xue, Angelika Holler, Cecile Voisine, Mario Perro, Judith King, Farnaz Fallah-Arani, Barry Flutter, Ronjon Chakraverty, Hans J. Stauss, Emma C. Morris
Journal: Blood
Blood (2011) 117 (25): 6813–6824.
https://doi.org/10.1182/blood-2010-08-304568
Published: 2011
Journal Articles

LMP2-Specific TCR Gene Therapy for Hodgkin Lymphoma - Design of a Dominant TCR Construct for Immunotherapy.

Daniel P. Hart, MD, Sharyn Thomas, Shao-an Xue, Emma C. Morris, MD, PhD, Hans J. Stauss, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2762.
https://doi.org/10.1182/blood.V110.11.2762.2762
Published: 2007
Journal Articles

Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression

Peng H. Tan, John B. Yates, Shao-An Xue, Cliburn Chan, William J. Jordan, Jennifer E. Harper, Martin P. Watson, Rong Dong, Mary A. Ritter, Robert I. Lechler, Giovanna Lombardi, Andrew J. T. George
Journal: Blood
Blood (2005) 106 (9): 2936–2943.
https://doi.org/10.1182/blood-2005-05-1826
Published: 2005
Journal Articles

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene–transduced human T cells

Shao-An Xue, Liquan Gao, Daniel Hart, Roopinder Gillmore, Waseem Qasim, Adrian Thrasher, Jane Apperley, Boris Engels, Wolfgang Uckert, Emma Morris, Hans Stauss
Journal: Blood
Blood (2005) 106 (9): 3062–3067.
https://doi.org/10.1182/blood-2005-01-0146
Published: 2005
Journal Articles

Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy

Peng H. Tan, Sven C. Beutelspacher, Shao-An Xue, Yao-He Wang, Peter Mitchell, James C. McAlister, D. Frank P. Larkin, Myra O. McClure, Hans J. Stauss, Mary A. Ritter, Giovanna Lombardi, Andrew J. T. George
Journal: Blood
Blood (2005) 105 (10): 3824–3832.
https://doi.org/10.1182/blood-2004-10-3880
Published: 2005
Includes: Supplemental data
Journal Articles

T Cell Receptor Gene Transfer to Produce MHC Class I-Restricted CD4 Helper T Cells: Implications for Immunotherapy of Leukaemia.

Emma Morris, MD, PhD, Aristotle Tsallios, MSc, Gavin Bendle, MSc, Shao-an Xue, PhD, Hans Stauss, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 5262.
https://doi.org/10.1182/blood.V104.11.5262.5262
Published: 2004
Journal Articles

TCR gene therapy of leukemia

Hans J. Stauss, Emma C. Morris, Shao-an Xue
Journal: Blood
Blood (2003) 102 (10): 3462–3463.
https://doi.org/10.1182/blood-2003-09-3020
Published: 2003