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Angelika Holler
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Journal Articles

Enhancement of mTORC1 Activity in Engineered Therapeutic CD4+ T Cells Amplifies Tumour Infiltration but Impairs Cytotoxicity

Francesca Emily Sillito, Angelika Holler, Aideen T O'Neill, Lauren A Callender, Sian M Henson, Hans Stauss, Ronjon Chakraverty
Journal: Blood
Blood (2024) 144 (Supplement 1): 7196.
https://doi.org/10.1182/blood-2024-207047
Published: 2024
Journal Articles

CD27 is required for protective lytic EBV antigen–specific CD8 + T-cell expansion

Yun Deng, Bithi Chatterjee, Kyra Zens, Hana Zdimerova, Anne Müller, Patrick Schuhmachers, Laure-Anne Ligeon, Antonino Bongiovanni, Riccarda Capaul, Andrea Zbinden, Angelika Holler, Hans Stauss, Wolfgang Hammerschmidt, Christian Münz
Journal: Blood
Blood (2021) 137 (23): 3225–3236.
https://doi.org/10.1182/blood.2020009482
Published: 2021
Includes: Supplemental data
Journal Articles

A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation

Emma C Morris, Rita Tendeiro-Rego, Rachel Richardson, MSc, Thomas A Fox, BSc, MSc, MRCP, Francesca Sillito, BSc, MRCP, FRCPath, Angelika Holler, Sharyn Thomas, Shao-An Xue, Irma Alicia Martínez-Dávila, Emma Nicholson, Mandana Ahmadi, Judith King, Panagiotis Kottaridis, Ronjon Chakraverty, BMBS, PhD, Kirsty Thomson, Stephen Robinson, MBBS, PhD BSc, Andres E. Virchis, FRCP, FRCPath, Asim Khwaja, Michelle Quaye, Hong Zhan, Waseem Qasim, MBBS, PhD, Nourredine Himoudi, Jacqueline Barry, Natalie Mount, PhD, Terri Gaskell, Michaela Sharpe, Shannon M Inman, Kurt C. Gunter, MD, Hans Stauss
Journal: Blood
Blood (2019) 134 (Supplement_1): 1367.
https://doi.org/10.1182/blood-2019-128044
Published: 2019
Journal Articles

T Cells Engineered For Resistance To Mycophenolate Mofetil Demonstrate Enhanced Expansion and Improved Tumour Control In Immunosuppressed Hosts

James Edward Griffin, MD, Shoa-An Xue, Benjamin J Carpenter, Pedro Velica, PhD, Angelika Holler, Sara Ghorashian, MD, Emma Nicholson, MD, Martin Pule, MD, Ronjon Chakraverty, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4486.
https://doi.org/10.1182/blood.V122.21.4486.4486
Published: 2013
Journal Articles

Targeting Therapeutic T Cells to Tumour Niches.

Ben Carpenter, MD, Sara Ghorashian, MD, Emma Nicholson, MD, James Edward Griffin, MD, Maryam Ahmadi, PhD, Angelika Holler, Barry Flutter, PhD, Noha Edwards, Hans Stauss, MD, PhD, Emma Morris, MD, PhD, Ronjon Chakraverty, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3009.
https://doi.org/10.1182/blood.V120.21.3009.3009
Published: 2012
Journal Articles

Enhancing the Efficacy of T Cell Receptor (TCR) Gene Therapy by Co-Transfer of TCR and Additional CD3 Molecules Into CD4+ T Cells

Emma K Nicholson, MD, Maryam Ahmadi, PhD, Angelika Holler, Rebecca Pike, PhD, Ben Carpenter, MD, Sharyn Thomas, PhD, Sara Ghorashian, MD, Shao-An Xue, PhD, Hans Stauss, MD, PhD, Emma Morris, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2044.
https://doi.org/10.1182/blood.V120.21.2044.2044
Published: 2012
Journal Articles

CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens

Sara Ghorashian, MD, Ben Carpenter, MD, Angelika Holler, Emma Nicholson, MD, Maryam Ahmadi, PhD, Mathias Zech, MD, Clare Bennett, PhD, Shao-An Xue, PhD, Emma Morris, MD, PhD, Hans Stauss, MD, PhD, Ronjon Chakraverty, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 952.
https://doi.org/10.1182/blood.V120.21.952.952
Published: 2012
Journal Articles

CD3 limits the efficacy of TCR gene therapy in vivo

Maryam Ahmadi, Judith W. King, Shao-An Xue, Cécile Voisine, Angelika Holler, Graham P. Wright, Jonathan Waxman, Emma Morris, Hans J. Stauss
Journal: Blood
Blood (2011) 118 (13): 3528–3537.
https://doi.org/10.1182/blood-2011-04-346338
Published: 2011
Journal Articles

Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination

Constandina Pospori, Shao-An Xue, Angelika Holler, Cecile Voisine, Mario Perro, Judith King, Farnaz Fallah-Arani, Barry Flutter, Ronjon Chakraverty, Hans J. Stauss, Emma C. Morris
Journal: Blood
Blood (2011) 117 (25): 6813–6824.
https://doi.org/10.1182/blood-2010-08-304568
Published: 2011